Researcher Database

SUGAHARA, Takuya

FacultyGraduate School of Agriculture Department of Bioscience
PositionProfessor
Last Updated :2019/09/06

Researcher Profile and Settings

Profile and Settings

Name

  • Name

    SUGAHARA, Takuya

Profile & Settings

  • ハンドル

    mars95

Affiliations

Affiliation & Job

  • Section

    Faculty of Agriculture Department of Bioresources
  • Job title

    Associate Professor

Education, Etc.

Education

  • 1993
  • 1990
  • 1988
  • 1993, Kyushu University, Graduate School, Division of Agriculture, Department of Food Science and Technology
  • 1990, Kyushu University, Graduate School, Division of Agriculture, Department of Food Science and Technology
  • 1988, Kyushu University, Faculty of Agriculture, Department of Food Science and Technology

Degree

  • Ph. D

その他基本情報

Association Memberships

  • The INTERNATIONAL SOCIETY FOR NUTRACEUTICALS AND FUNCTIONAL FOODS (ISNFF)
  • JAPANESE SOCIETY OF ALLERGOLOGY
  • Japan Society for Bioscience
  • Biotechnology
  • and Agrochemistry
  • Japanese Association for Animal Cell Technology

Committee Memberships

  • 2019/03 - Today
  • 2019/03 - Today
  • 2018/08 - Today
  • 2018/04 - Today
  • 2018/04 - Today
  • 2015/04 - Today
  • 2015/04 - Today
  • 2012/04 - Today
  • 2001 - 2002
  • 2007/04 - Today
  • 2001 - 2002, Japan Society for Bioscience, Biotechnology, and Agrochemistry, Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • 2007 - 2008, Japan Society for Bioscience, Biotechnology, and Agrochemistry, Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • 2011 - 2012, Japan Society for Bioscience, Biotechnology, and Agrochemistry, Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • 2009 - 2010, Japan Society for Bioscience, Biotechnology, and Agrochemistry, Japan Society for Bioscience, Biotechnology, and Agrochemistry

Academic & Professional Experience

  • 2016/04 - Today, Professor, Graduate School of Agriculture, Ehime University
  • 2016/04 - Today
  • 2013/04 - Today
  • 2013/02 - 2016/03
  • 2007/04 - 2013/02
  • 2006/07 - 2007/03
  • 2002/02 - 2002/11
  • 1994/01 - 2006/06
  • 2007 - , - Ehime University
  • 2006 - 2007,  Ehime University
  • 2002 - , University of Texas Health Center at Tyler
  • 1994 - 2006,  Ehime University

Research Activities

Research Areas, Etc.

Research Areas

  • Agricultural chemistry, Food science
  • Process/Chemical engineering, Biofunction/Bioprocess
  • Society medicine, Hygiene and public health

Research Interests

  • Nobiletin
  • TLR4
  • JNK
  • Cell Biology
  • Food Science and Nutritional Chemistry

Book, papers, etc

Published Papers

  • Inhibitory effect of aqueous extract of <i>Cuminum cyminum</i> L. seed on degranulation of RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice., M. Hada, K. Nishi, M. Ishida, H. Onda, S. Nishimoto and T. Sugahara, Cytotechnology, 2019/04, [Refereed]
  • Lysozyme from hen egg white ameliorates lipopolysaccharide-induced systemic inflammation in mice, A. Tagashira, K. Nishi and T. Sugahara, Cytotechnology, 2019/04, [Refereed]
  • The design of 92 new 9-Norlignan derivatives and their effect on the cell viabilities of cancer and insect cells., S. Yamauchi, Y. Shoji, A. Nishimoto, M. Uzura, H. Nishiwaki, K. Nishi and T. Sugahara, J. Agric. Food Chem., 2019/07, [Refereed]
  • Anti-degranulation Activity of Caffeine: <i>In Vitro</i> and <i>In Vivo</i> Study, A.D. Nugrahini, M. Ishida, K. Nishi, T. Nakagawa and T. Sugahara, 2019, [Refereed]
  • Anti-inflammatory effect of aqueous extract from Kawachi-bankan (<i>Citrus maxima</i>) peel <i>in vitro</i> and <i>in vivo</i>., M. Ishida, C. Takekuni, K. Nishi and T. Sugahara, Cytotechnology, 2019/08, [Refereed]
  • A simple and versatile authenticity assay of coffee products by single nucleotide polymorphism genotyping, T. Nakagawa, M. Doi, K. Nishi, T. Sugahara, H. Nishimukai and M. Asano, Biosci. Biotechnol. Biochem., 2019/10, [Refereed]
  • Anti-allergy potential of petis extract on immunoglobulin E production by U266 cells, R.V. Tansy, A.B.N. Putra, T. Sugahara, Canrea Journal, 2018/12, [Refereed]
  • IgE production-suppressing effect of asam kandis (dried Garcinia xantochymus) extracts by mouse hybridoma aDNP-Hy Cells., N. Supardi, A. Sumarpo, R. Sutejo, A.B.N. Putra, N. Kageyama, M. Kawano and T. Sugahara, Biodiversitas, 2018/01, [Refereed]
  • Immunostimulatory effect of tempoyak (fermented durian) on inducing cytokine production (IL-6 and TNF- ) by RAW 264.7 cells., S. Susanto, A. Sumarpo, A.A. Parikesit, A.B.N. Putra, E. Ishii, K. Tabuchi and T. Sugahara, Biodiversitas, 2018/01, [Refereed]
  • Inhibitory effect of Japanese black vinegar on IgE-mediated degranulation of RBL-2H3 cells and a murine model of Japanese cedar pollinosis., S. Awane, K. Nishi, M. Ishida, M. Nagano, K. Hashiguchi, A. Fujiic and T. Sugahara, Cytotechnology, 2018/06, [Refereed]
  • Anti-inflammatory effect of lysozyme from hen egg white on mouse peritoneal macrophages., A. Tagashira, K. Nishi, S. Matsumoto, M. Ishida and T. Sugahara, Cytotechnology, 2018/06, [Refereed]
  • Immunomodulatory activity of octenyl succinic anhydride modified porang (Amorphophallus oncophyllus) glucomannan on mouse macrophage-like J774.1 cells and mouse primary peritoneal macrophages., S. Gurusmatika, K. Nishi, E. Harmayani, Y. Pranoto and T. Sugahara, Molecules, 2017/07, [Refereed]
  • Suppressive effect of ethanol extract from passion fruit seeds on IgE production., A. Mizusaki, K. Nishi, H. Nishiwaki, M. Ishida, T. Tamamoto and T. Sugahara, J. Funct. Foods, 2017/05, [Refereed], 10.1016/j.jff.2017.02.030
  • Immunostimulatory effect of dried bonito extract on mouse Macrophage cell lines and mouse primary peritoneal macrophages., M. Ishida, K. Nishi, K. Shinohara, N. Kunihiro, K. Osajima, T. Suemitsu and T. Sugahara, Cytotechnology, 2017/04, [Refereed], 10.1007/s10616-016-0053-4
  • Effect of mandarin orange yogurt on allergic conjunctivitis induced by conjunctival allergen challenge., Y. Hara, A. Shiraishi, Y. Sakane, Y. Takezawa, T. Kamao, Y. Ohashi, S. Yasunaga and T. Sugahara, Invest. Ophth. Vis. Sci., 2017/06, [Refereed]
  • Suppressive effect of ethanol extract from mango (<i>Mangifera indica</i> L.) peel on IgE production <i>in vitro</i> and <i>in vivo</i>., M. Ishida, T. Sasaki, K. Nishi, T. Tamamoto and T. Sugahara, Biosci. Biotechnol. Biochem., 2018/05, [Refereed]
  • Syntheses of cytotoxic novel arctigenin derivatives bearing halogen and alkyl groups on aromatic rings., S. Yamauchi, T. Wukirsari, Y. Ochi, H. Nishiwaki, K. Nishi, T. Sugahara, K. Akiyama and T. Kishida, Bioorg. Med. Chem. Lett., 2017/09, [Refereed], 10.1016/j.bmcl.2017.06.070
  • Immunostimulatory effect of aqueous extract of Coriandrum sativum L. seed on macrophages., M. Ishida, K. Nishi, N. Kunihiro, H. Onda, S. Nishimoto and T. Sugahara, J. Sci. Food Agr., 2017/11, [Refereed], 10.1002/jsfa.8341
  • Efficacy of chlorophyll c2 for seasonal allergic rhinitis; single-center double blind randomized control trial., T. Fujiwara, N. Nishida, J. Nota, T. Kitani, K. Aoishi, H. Takahashi, T. Sugahara and N. Hato, Eur. Arch. Oto Rhino Laryngol., 2016/12, [Refereed], 10.1007/s00405-016-4133-z
  • Immunostimulatory activity of snake fruit peel extract on murine macrophage-like J774.1 cells., S. Wijanarti, A.B.N. Putra, K. Nishi, E. Harmayani and T. Sugahara, Cytotechnology, 2016/10, [Refereed], 10.1007/s10616-015-9925-2
  • Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids., S. Yamauchi, R. Tanimura, H. Nishiwaki, K. Nishi, T. Sugahara, M. Maruyama, Y. Ano, K. Akiyama and T. Kishida, Bioorg. Med. Chem. Lett., 2016/07, [Refereed], 10.1016/j.bmcl.2016.05.020
  • Immunostimulatory effect of spinach aqueous extract on mouse macrophage-like J774.1 cells and mouse primary peritoneal macrophages., M. Ishida, S. Ose, K. Nishi and T. Sugahara, Biosci. Biotechnol. Biochem., 2016/06, [Refereed], 0916-8451, 10.1080/09168451.2016.1146068
  • Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells., S. Yasunaga, M. Domen, K. Nishi, A. Kadota and T. Sugahara, J. Funct. Foods, 2016/12, [Refereed], 10.1016/j.jff.2016.09.025
  • Effect of the structure of dietary epoxylignan on its cytotoxic activity: relationship between the structure and the activity of 7,7'-epoxylignan and the introduction of apoptosis by caspase 3/7., T. Wukirsari, H. Nishiwaki, K. Nishi, T. Sugahara, K. Akiyama, T. Kishida and S. Yamauchi, Biosci. Biotechnol. Biochem., 2016/04, [Refereed], 10.1080/09168451.2015.1123603
  • Effect of concurrent administration of nobiletin and β-lactoglobulin on the symptoms of Japanese cedar pollinosis models in mice., S. Yasunaga, A. Kadota, T. Kikuchi, C. Kubo, K. Nishi and T. Sugahara, J. Funct. Foods, 2016/04, [Refereed], 10.1016/j.jff.2016.01.045
  • Inhibitory effects of enzyme-treated dried sardine extract on IgE-mediated degranulation of RBL-2H3 cells and a murine model of Japanese cedar pollinosis., S. Awane, M. Nakamoto, K. Nishi, K. Osajima, T. Suemitsu and T. Sugahara, RSC Advances, 2016, [Refereed], 10.1039/c6ra14967g
  • Effects of an equol-producing bacterium isolated from human feces on isoflavone and lignan metabolism in mice., Tamura M, Hori S, Nakagawa H, Yamauchi S, Sugahara T, J. Sci. Food Agr., 2016/07, [Refereed], 0022-5142, 10.1002/jsfa.7490
  • Methoxychlor enhances degranulation of murine mast cells by regulating FcεRI-mediated signal transduction., Yasunaga S, Nishi K, Nishimoto S, Sugahara T, Journal of Immunotoxicology, 2015/07, [Refereed], 1547-691X, 10.3109/1547691X.2014.962122
  • Jellyfish collagen stimulates maturation of mouse bone marrow-derived dendritic cells., A.B.N. Putra, K. Nishi, R. Shiraishi, M. Doi and T. Sugahara, J. Funct. Foods, 2015/04, [Refereed], 10.1016/j.jff.2015.02.008
  • Ishizuchi dark tea suppresses IgE-mediated degranulation of RBL-2H3 cells and nasal rubbing behavior of pollinosis in mice., M. Kondo, K. Nishi and T. Sugahara, J. Funct. Foods, 2015/04, [Refereed], 10.1016/j.jff.2015.02.045
  • Acute larvicidal activity against mosquitoes and oxygen consumption inhibitory activity of dihydroguaiaretic acid derivatives., Nishiwaki H, Tabara Y, Kishida T, Nishi K, Shuto Y, Sugahara T, Yamauchi S, Journal of agricultural and food chemistry, 2015/03, [Refereed], 0021-8561, 10.1021/jf504816a
  • Revised stereochemistry of ficifolidione and its biological activities against insects and cells., Nishiwaki H, Fujiwara S, Wukirsari T, Iwamoto H, Mori S, Nishi K, Sugahara T, Yamauchi S, Shuto Y, Journal of natural products, 2015/01, [Refereed], 0163-3864, 10.1021/np5006746
  • Gene transfection into HeLa cells by vesicles containing cationic peptide lipid., Y. Ohama, Y. Heike, T. Sugahara, K. Sakata, N. Yoshimura, Y. Hisaeda, M. Hosokawa, S. Takashima and K. Kato, Biosci. Biotechnol. Biochem., 2015, [Refereed], 10.1271/bbb.69.1453
  • Isoflavone changes during fermentation of kerandang (Canavalia virosa) milk using Lactobacillus plantarum-pentosus and its anticancer activity., D.T. Farianti, T. Sugahara, E.S. Rahayu, M.N. Cahyanto , U. Santoso and K. Nishi, Agriculture and Natural Resources, 2015, [Refereed]
  • Activation of J774.1 murine macrophages by lactate dehydrogenase., Daifuku M, Nishi K, Okamoto T, Sugahara T, Cytotechnology, 2014/12, [Refereed], 0920-9069, 10.1007/s10616-013-9646-3
  • The major whey protein -lactoglobulin inhibits IgE-mediated degranulation of RBL-2H3 cells and passive cutaneous anaphylaxis in mice., K. Nishi, M. Teranishi, S. Yasunaga, M. Iitsuka, S. Matsumoto and T. Sugahara, Int. Dairy J., 2014/11, [Refereed], 10.1016/j.idairyj.2014.05.006
  • Studies on anti-allergic activity of Sargassum horneri extract., H. Yoshioka, M. Ishida, K. Nishi, H. Oda, H. Toyohara and T. Sugahara, J. Funct. Foods, 2014/09, [Refereed], 10.1016/j.jff.2014.06.002
  • Cytotoxic activity of butane type of 1,7-seco-2,7'-cyclolignanes and apoptosis induction by Caspase 9 and 3., Wukirsari T, Nishiwaki H, Nishi K, Sugahara T, Akiyama K, Kishida T, Yamauchi S, Bioorganic & Medicinal Chemistry Letters, 2014/09, [Refereed], 0960-894X, 10.1016/j.bmcl.2014.07.033
  • Nobiletin, a polymethoxy flavonoid, exerts anti-allergic effect by suppressing activation of phosphoinositide 3-kinase., S. Onishi, K. Nishi, S. Yasunaga, A. Muranaka, K. Maeyama, A. Kadota and T. Sugahara, J. Funct. Foods, 2014/07, [Refereed], 10.1016/j.jff.2013.12.005
  • Activation of macrophages stimulated by the bengkoang fiber extract through toll-like receptor 4., Kumalasari ID, Nishi K, Putra AB, Sugahara T, Food & Function, 2014/07, [Refereed], 2042-6496, 10.1039/c3fo60360a
  • Cytotoxic activity of dietary lignan and its derivatives: structure-cytotoxic activity relationship of dihydroguaiaretic acid., Wukirsari T, Nishiwaki H, Nishi K, Sugahara T, Akiyama K, Kishida T, Yamauchi S, Journal of Agricultural and Food Chemistry, 2014/06, [Refereed], 0021-8561, 10.1021/jf5010572
  • Tributyltin induces cell cycle arrest at G1 phase in the yeast Saccharomyces cerevisiae., Sekito T, Sugimoto N, Ishimoto M, Kawano-Kawada M, Akiyama K, Nishimoto S, Sugahara T, Kakinuma Y, The Journal of Toxicological Sciences, 2014/04, [Refereed], 0388-1350, 10.2131/jts.39.311
  • Jellyfish collagen stimulates production of TNF-α and IL-6 by J774.1 cells through activation of NF-κB and JNK via TLR4 signaling pathway., Putra AB, Nishi K, Shiraishi R, Doi M, Sugahara T, Molecular Immunology, 2014/03, [Refereed], 0161-5890, 10.1016/j.molimm.2013.11.003
  • Immunomodulatory activity of Bengkoang (Pachyrhizus erosus) fiber extract in vitro and in vivo., Kumalasari ID, Nishi K, Harmayani E, Raharjo S, Sugahara T, Cytotechnology, 2014/01, [Refereed], 0920-9069, 10.1007/s10616-013-9539-5
  • Antiproliferative activity and its underlying mechanisms of methanol extract from leaves of Saururus chinensis (Lour.) Baill. on mouse Colon-26 carcinoma cells., M. Daifuku, K. Nishi, H. Nishiwaki, I.-H. Kim, S. Kim and T. Sugahara, J. Appl. Res. Nat. Prod., 2014, [Refereed]
  • Cellular mechanism of the cytotoxic effect of extracts from Syzygium polyanthum leaves., Sulistiyani, S. Falah, W.T. Wahyuni, T. Sugahara, S. Tachibana and Syaefudin, Am. J. Drug Discov. Dev., 2014, [Refereed], 10.3923/ajdd.2014.90.101
  • Structure-cytotoxic activity relationship of sesquilignan, morinol A., Yamauchi S, Kawahara S, Wukirsari T, Nishiwaki H, Nishi K, Sugahara T, Akiyama K, Kishida T, Bioorganic & Medicinal Chemistry Letters, 2013/09, [Refereed], 0960-894X, 10.1016/j.bmcl.2013.06.067
  • Quantitative structure-activity relationship analysis of antifungal (+)-dihydroguaiaretic acid using 7-phenyl derivatives., Hasebe A, Nishiwaki H, Akiyama K, Sugahara T, Kishida T, Yamauchi S, Journal of Agricultural and Food Chemistry, 2013/09, [Refereed], 0021-8561, 10.1021/jf4015526
  • Effect of bengkoang (Pachyrhizus erosus) fiber extract on murine macrophage-like J774.1 cells and mouse peritoneal macrophages., I.D. Kumalasari, K. Nishi, E. Harmayani, S. Raharjo and T. Sugahara, J. Funct. Foods, 2013/04, [Refereed], 10.1016/j.jff.2012.12.005
  • Inhibitory effect of chlorophyll c2 from brown algae, Sargassum horneri, on degranulation of RBL-2H3 cells., H. Yoshioka, A. Kamata, T. Konishi, J. Takahashi, H. Oda, T. Tamai, H. Toyohara and T. Sugahara, J. Funct. Foods, 2013/01, [Refereed], 10.1016/j.jff.2012.10.006
  • Inhibitory effect of aqueous spinach extract on degranulation of RBL-2H3 cells., Ishida M, Nishi K, Watanabe H, Sugahara T, Food Chemistry, 2013/01, [Refereed], 0308-8146, 10.1016/j.foodchem.2012.08.079
  • Phenylhydroquinone induces loss of thymocytes through cell cycle arrest and apoptosis elevation in p53-dependent pathway., Nakata Y, Nishi K, Nishimoto S, Sugahara T, The Journal of Toxicological Sciences, 2013, [Refereed], 0388-1350, 10.2131/jts.38.325
  • Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs., Kurogi K, Alazizi A, Liu MY, Sakakibara Y, Suiko M, Sugahara T, Liu MC, Biochemical Pharmacology, 2012/11, [Refereed], 0006-2952, 10.1016/j.bcp.2012.08.009
  • Effect of substituents at phenyl group of 7,7'-dioxo-9,9'-epoxylignane on antifungal activity., Nishiwaki H, Ouchi M, Matsugi J, Akiyama K, Sugahara T, Kishida T, Yamauchi S, Bioorganic & Medicinal Chemistry Letters, 2012/11, [Refereed], 0960-894X, 10.1016/j.bmcl.2012.08.078
  • Immunomodulatory effects of citrus fruit auraptene in vitro and in vivo., S. Nishimoto, A. Muranaka, K. Nishi, A. Kadota and T. Sugahara, J. Funct. Foods, 2012/10, [Refereed], 10.1016/j.jff.2012.06.005
  • Immunomodulatory effects of lactate dehydrogenase in vitro and in vivo., M. Daifuku, K. Nishi, T. Okamoto, S. Nishimoto and T. Sugahara, J. Funct. Foods, 2012/10, [Refereed], 10.1016/j.jff.2012.07.005
  • Immunochromatographic assay of cadmium levels in oysters., Nishi K, Kim IH, Itai T, Sugahara T, Takeyama H, Ohkawa H, Talanta, 2012/08, [Refereed], 0039-9140, 10.1016/j.talanta.2012.04.028
  • Immunostimulatory effect of b-cryptoxanthin in vitro and in vivo., K. Nishi, A. Muranaka, S. Nishimoto, A. Kadota and T. Sugahara, J. Funct. Foods, 2012/07, [Refereed], 10.1016/j.jff.2012.04.001
  • Effect of collagens from jellyfish and bovine Achilles tendon on the activity of J774.1 and mouse peritoneal macrophage cells., A.B.N. Putra, H. Morishige, S. Nishimoto, K. Nishi, R. Shiraishi, M. Doi and T. Sugahara, J. Funct. Foods, 2012/04, [Refereed], 10.1016/j.jff.2012.02.011
  • Nobiletin suppresses adipocyte differentiation of 3T3-L1 cells by an insulin and IBMX mixture induction., Kanda K, Nishi K, Kadota A, Nishimoto S, Liu MC, Sugahara T, Biochimica et Biophysica Acta, 2012/04, [Refereed], 0006-3002, 10.1016/j.bbagen.2011.11.015
  • Evaluation of immunostimulatory effect of the arrowroot (Maranta arundinacea. L) in vitro and in vivo., Kumalasari ID, Harmayani E, Lestari LA, Raharjo S, Asmara W, Nishi K, Sugahara T, Cytotechnology, 2012/03, [Refereed], 0920-9069, 10.1007/s10616-011-9403-4
  • Immunostimulatory effects of water extract from bulbus arteriosus in tuna in vitro., M. Daifuku, K. Nishi, T. Okamoto, H. Nakano, S. Nishimoto and T. Sugahara, J. Funct. Foods, 2012/01, [Refereed], 10.1016/j.jff.2011.12.002
  • (-)-Secoisolariciresinol attenuates high-fat diet-induced obesity in C57BL/6 mice., Tominaga S, Nishi K, Nishimoto S, Akiyama K, Yamauchi S, Sugahara T, Food & Function, 2012/01, [Refereed], 2042-6496, 10.1039/c1fo10166h
  • Immunostimulatory effects of collagen from jellyfish in vivo., Morishige H, Sugahara T, Nishimoto S, Muranaka A, Ohno F, Shiraishi R, Doi M, Cytotechnology, 2011/10, [Refereed], 0920-9069, 10.1007/s10616-011-9371-8
  • Heavy oil fraction induces the dysplastic sperm in male mouse., S. Nishimoto, K. Akiyama, Y. Kakinuma, S. Kitamura and T. Sugahara, J. Toxicol. Sci., 2011/08, 10.2131/jts.36.487
  • Immunomodulatory effect of (-)-matairesinol <i>in vivo</i> and <i>ex vivo</i>., M. Yamawaki, K. Nishi, S. Nishimoto, S. Yamauchi, K. Akiyama, T. Kishida, M. Maruyama, H. Nishiwaki and T. Sugahara, Biosci. Biotechnol. Biochem., 2011, 0916-8451|1347-6947, 10.1271/bbb.100781
  • Disruption of ion homeostasis by verrucosin and its related compound., K. Akiyama, J. Tone, S. Yamauchi, T. Sugahara, M. Maruyama and Y. Kakinuma, Biosci. Biotechnol. Biochem., 2011, 0916-8451|1347-6947, 10.1271/bbb.110004
  • Inhibition of myotube formation by paraquat in the myoblast cell line C2C12., K. Akiyama, J. Tone, M. Okabe, S. Nishimoto, T. Sugahara and Y. Kakinuma, J. Toxicol. Sci., 2011/04, [Refereed], 0388-1350|1880-3989, 10.2131/jts.36.243
  • Immunostimulation effects of yellowtail heart extracts <i>in vitro</i> and <i>in vivo</i>., M. Daifuku, Y. Yaguchi, K. Nishi, T. Okamoto, H. Nakano, S. Nishimoto, S. Nishikawa, H. Yamashita, S. Takimoto and T. Sugahara, Biosci. Biotechnol. Biochem., 2011, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.100713
  • Bfr1p is responsible for tributyltin resistance in Schizosaccharomyces pombe., K. Akiyama, T. Iwaki, N. Sugimoto, S. Chardwiriyapreecha, M. Kawano, S. Nishimoto, T. Sugahara, T. Sekito and Y. Kakinuma, J. Toxicol. Sci., 2011/02, [Refereed], 0388-1350|1880-3989, 10.2131/jts.36.117
  • Immunostimulatory <i>in vitro</i> and <i>in vivo</i> effects of a water-soluble extract from kale., K. Nishi, A. Kondo, T. Okamoto, H. Nakano, M. Daifuku, S. Nishimoto, K. Ochi, T. Takaoka and T. Sugahara, Biosci. Biotechnol. Biochem., 2011, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.100490
  • Antifungal activity of morinol B derivatives of tetrahydropyran sesquilignan., K. Masuda, H. Nishiwaki, K. Akiyama, S. Yamauchi, M. Maruyama, T. Sugahara and T. Kishida, Biosci. Biotechnol. Biochem., 2010, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.100422
  • Zebrafish as a model for the study of the phase II cytosolic sulfotransferases., T.-A. Liu, S. Bhuiyan, M.-Y. Liu, T. Sugahara, Y. Sakakibara, M. Suiko, S. Yasuda, Y. Kakuta, M. Kimura, F.E. Williams and M.-C. Liu, Curr. Drug Metab., 2010, [Refereed], 10.2174/138920010791636158
  • IgE suppressive activity of (-)-matairesinol and structure-activity relationship., S. Kawahara, I. Iwata, E. Fujita, M. Yamawaki, H. Nishiwaki, T. Sugahara, S. Yamauchi, K. Akiyama and T. Kishida, Biosci. Biotechnol. Biochem., 2010, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.100275
  • Improved syntheses of morinol C and D by employing Mizoroki-Heck 4 reaction and their cytotoxic and antimicrobial activities., K. Ogura, T. Sugahara, M. Maruyama, K. Akiyama and S. Yamauchi, Biosci. Biotechnol. Biochem., 2010, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.100255
  • Proteose peptone fraction of bovine milk depressed IgE production <i>in vitro</i> and <i>in vivo</i>., F. Ohno, T. Sugahara, K. Kanda and S. Nishimoto, Biosci. Biotechnol. Biochem., 2010, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.90809
  • In vitro and in vivo anti-tumor effects of novel Span 80 vesicles containing immobilized Eucheuma serra agglutinin., Y. Omokawa, T. Miyazaki, P. Walde, K. Akiyama, T. Sugahara, S. Masuda, A. Inada, Y. Ohnishi, T. Saeki and K. Kato, Int. J. Pharm., 2010, [Refereed], 0378-5173, 10.1016/j.ijpharm.2010.01.033
  • Oral administration of paraquat perturbs immunoglobulin productivity in mouse., M. Okabe, S. Nishimoto, T. Sugahara, K. Akiyama and Y. Kakinuma, J. Toxicol. Sci., 2010/04, 0388-1350|1880-3989, 10.2131/jts.35.257
  • The differentiation of myoblast cells to myotube by paraquat., M. Okabe, K. Akiyama, S. Nishimoto, T. Sugahara and Y. Kakinuma, Animal Cell Technology: Basic & Applied Aspects, 2010
  • The effect of secoisolariciresinol on 3T3-L1 adipocytes and the relationship between molecular structure and the activity., S. Tominaga, T. Sugahara, S. Nishimoto, M. Yamawaki, Y. Nakashima, T. Kishida, K. Akiyama, M. Maruyama and S. Yamauchi, Animal Cell Technology: Basic & Applied Aspects, 2010
  • The effects of pesticides on immune cells., S. Nishimoto, K. Kanda, M. Okabe, K. Akiyama, Y. Kakinuma and T. Sugahara, Animal Cell Technology: Basic & Applied Aspects, 2010
  • Heavy oil fractions induce negative influences on mouse immune system., S. Nishimoto, K. Kanda, M. Yamawaki, M. Okabe, K. Akiyama, Y. Kakinuma and T. Sugahara, J. Toxicol. Sci., 2009/10, [Refereed], 0388-1350, 10.2131/jts.34.459
  • Tributyltin induces Yca1p-dependent cell death of yeast Saccharomyces cerevisiae., T. Chahomchuen, K. Akiyama, T. Sekito, N. Sugimoto, M. Okabe, S. Nishimoto, T. Sugahara and Y. Kakinuma, J. Toxicol. Sci., 2009/10, [Refereed], 0388-1350, 10.2131/jts.34.541
  • Severe abnormalities in the reproductive organs of mice caused by chemical substances contained in heavy oil., S. Nishimoto, M. Yamawaki, K. Akiyama, S. Kitamura and T. Sugahara, J. Toxicol. Sci., 2009/04, [Refereed], 0388-1350, 10.2131/jts.34.239
  • Paraquat modulates the differentiation of C2C12 cells to myotube., M. Okabe, K. Akiyama, S. Nishimoto, T. Sugahara and Y. Kakinuma, Interdisciplinary Studies on Environmental Chemistry: Environmental Research in Asia for Establishing a Scientist's Network, 2009
  • Abnormal response induced by pesticides on mammalian immune system., S. Nishimoto, K. Kanda, M. Okabe, K. Akiyama, Y. Kakinuma and T. Sugahara, Interdisciplinary Studies on Environmental Chemistry: Environmental Research in Asia for Establishing a Scientist's Network, 2009
  • White sorghum (<i>Sorghum bicolor</i> (L.) Moench) bran extracts suppressed IgE production by U266 cells., T. Sugahara, S. Nishimoto, Y. Morioka, K. Nakano and K. Nakano, Biosci. Biotechnol. Biochem., 2009, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.90245
  • Inhibition of discoloration of yellowtail dark muscle by lignan., S. Yamauchi, T. Kishida, T. Sugahara, M. Yamawaki, S. Nishimoto, Y. Shinomiya and T. Yamamoto, Biosci. Biotechnol. Biochem., 2009, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.80830
  • Antimicrobial activity of stereoisomers of butane type of lignans., Y. Kawaguchi, S. Yamauchi, K. Masuda, H. Nishiwaki, K. Akiyama, M. Maruyama, T. Sugahara, T. Kishida and Y. KobaMASUDA, Hisashi NISHIWAKI, Koichi AKIYAMA, Masafumi MARUYAMA, Takuya SUGAHARA, Taro KISHIDA, Yojiro KOBA, Biosci. Biotechnol. Biochem., 2009, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.90167
  • Syntheses and antimicrobial activity of tetrasubstituted tetrahydrofuran lignan stereoisomers., T. Nakato, S. Yamauchi, R. Tago, K. Akiyama, M. Maruyama, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 2009, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.90107
  • The Effect of secoisolariciresinol on 3T3-L1 adipocytes and the relationship between molecular structure and the activity., S. Tominaga, T. Sugahara, S. Nishimoto, M. Yamawaki, Y. Nakashima, T. Kishida, K. Akiyama, M. Maruyama and S. Yamauchi, 2009, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.80393
  • Antimicrobial activity of stereoisomers of morinol A and B, tetrahydropyran sesquineolignan., K. Akiyama, S. Yamauchi, M. Maruyama, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 2009, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.80536
  • Characterization of amino acid recycling process in yeast autophagy., T. Chahomchuen, T. Sekito, K. Hondo, S. Nishimoto, T. Sugahara and Y. Kakinuma, Interdisciplinary Studies on Environmental Chemistry: Biological Responses to Chemical Pollutants, 2008
  • Vacuolar-type H+-translocating ATPase is the target of tributylin Chloride., K. Akiyama, S. Chardwiriyapreecha, T. Chahomchuen, N. Sugimoto, T. Sekito, S. Nishimoto, T. Sugahara and Y. Kakinuma, Interdisciplinary Studies on Environmental Chemistry: Biological Responses to Chemical Pollutants, 2008
  • Risk assessment of heavy oil on terrestrial mammals., S. Nishimoto, M. Yamawaki, S.-I. Kitamura, K. Akiyama, Y. Kakinuma and T. Sugahara, Interdisciplinary Studies on Environmental Chemistry: Biological Responses to Chemical Pollutants, 2008
  • The structure-activity relationship of flaxseed lignan, secoisolariciresinol., T. Sugahara, S. Yamauchi, S. Nishimoto, A. Kondo, F. Ohno, S. Tominaga, Y. Nakashima, T. Kishida, K. Akiyama, M. Maruyama and Y. Kakinuma, Interdisciplinary Studies on Environmental Chemistry: Biological Responses to Chemical Pollutants, 2008
  • Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid., S. Yamauchi, T. Masuda, T. Sugahara, Y. Kawaguchi, M. Ohuchi, T. Someya, J. Akiyama, S. Tominaga, M. Yamawaki, T. Kishida, K. Akiyama and M. Maruyama, Biosci. Biotechnol. Biochem., 2008, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.80461
  • The mode of action of the immunostimulatory effect of collagen from jellyfish., S. Nishimoto, Y. Goto, H. Morishige, R. Shiraishi, M. Doi, K. Akiyama, S. Yamauchi and T. Sugahara, Biosci. Biotechnol. Biochem., 2008, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.80154
  • Syntheses of all stereoisomers of goniodiol from yeast-reduction products and their antimicrobiological activity., T. Yoshida, S. Yamauchi, R. Tago, M. Maruyama, K. Akiyama, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 2008, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.80262
  • Structure-antibacterial activity relationship of 9-O,9'-O-demethyl (+)-virgatusin., R. Tago, M. Maruyama, K. Akiyama, T. Sugahara, T. Kishida, Y. Koba and S. Yamauchi, Biosci. Biotechnol. Biochem., 2008, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.70783
  • Effects of polyamines on proliferation and IgM productivity of human-human hybridoma, HB4C5 cells., T. Sugahara, S. Nishimoto and Y. Miyazaki, Cytotechnology, 2008, [Refereed], 0920-9069, 10.1007/s10616-007-9115-y
  • Stereoselective construction of tetra-substituted tetrahydrofuran compounds from benzylic hemiacetal in the presence of H2 and Pd catalyst: stereoselective synthesis of stereoisomer of (-)-virgatusin and antimicrobiological activity., T. Nakato, S. Yamauchi, R. Tago, K. Akiyama, M. Maruyama, T. Sugahara and T. Kishida, Biosci. Biotechnol. Biochem., 2008, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.70554
  • Immunostimulation effect of the jellyfish collagen., T. Sugahara, M. Ueno, Y. Goto, K. Akiyama, S. Yamauchi, R Shiraishi and M. Doi, Animal Cell Technology: Basic & Applied Aspects, 2008
  • First stereoselective synthesis of meso-secoisolariciresinol and comparison of biological activity with (+) and (-)-secoisolariciresinol., T. Sugahara, S. Yamauchi, A. Kondo, F. Ohno, S. Tominaga, Y. Nakashima, T. Kishida, K. Akiyama and M. Maruyama, Biosci. Biotechnol. Biochem., 2007, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.70358
  • Use of benzyl mesylate for the synthesis of tetrahydrofuran lignan: syntheses of 7,8-trans, 7',8'-trans, 7,7'-cis, 8,8'-cis-virgatusin stereoisomers., S. Yamauchi, T. Nakato, M. Tsuchiya, K. Akiyama, M. Maruyama, T. Sugahara and T. Kishida, Biosci. Biotechnol. Biochem., 2007, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.70236
  • Effect of benzylic structure of lignan on antioxidant activity., S. Yamauchi, T. Sugahara, J. Matsugi, T. Someya, T. Masuda, T. Kishida, K. Akiyama and M. Maruyama, Biosci. Biotechnol. Biochem., 2007, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.70275
  • Determination of the stereochemistry of the tetrahydropyran sesquineolignans morinols A and B., S. Yamauchi, T. Sugahara, K. Akiyama, M. Maruyama and T. Kishida, J. Nat. Prod., 2007, [Refereed], 0163-3864, 10.1021/np060461j
  • Antimicrobiological activity of lignan: effect of benzylic oxygen and stereochemistry of 2,3-dibenzyl-4-butanolide and 3,4-dibenzyltetrahydrofuran lignans on activity., K. Akiyama, M. Maruyama, S. Yamauchi, Y. Nakashima, T. Nakato, R. Tago, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 2007, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.70168
  • Antifungal activity of tetra-substituted tetrahydrofuran lignan, (-)-virgatusin, and its structure-activity relationship., K. Akiyama, S Yamauchi, T. Nakato, M. Maruyama, T. Sugahara and T. Kishida, Biosci. Biotechnol. Biochem., 2007, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.60696
  • Antibacterial activity of virgatusin-related compound., M. Maruyama, S. Yamauchi, K. Akiyama, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 2007, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.60429
  • The anti-tumor effect of Euchema serra agglutinin on colon cancer cells in vitro and in vivo., Y. Fukuda, T. Sugahara, M. Ueno, Y. Fukuta, Y. Ochi, K. Akiyama, T. Miyazaki, S. Masuda, A. Kawakubo and K. Kato, Anti-cancer Drugs, 2006/09, [Refereed], 0959-4973, 10.1097/01.cad.0000224458.13651.b4
  • Effect of benzylic oxygen on the cytotoxic activity for Colon 26 cell line of phenolic lignans., S. Yamauchi, T. Sugahara, Y. Nakashima, K. Abe, Y. Hayashi, K. Akiyama, T. Kishida and M. Maruyama, Biosci. Biotechnol. Biochem., 2006, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.60353
  • Radical and superoxide scavenging activity of matairesinol and oxidized matairesinol., S. Yamauchi, T. Sugahara, Y. Nakashima, A. Okada, K. Akiyama, T. Kishida, M. Maruyama and T. Masuda, Biosci. Biotechnol. Biochem., 2006, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.60096
  • Immunostimulation effect of the jellyfish collagen., T. Sugahara, M. Ueno, Y. Goto, R Shiraishi, M. Doi, K. Akiyama and S. Yamauchi, Biosci. Biotechnol. Biochem., 2006, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.60076
  • Molecular composition of non-ionic vesicles prepared from Span 80 or Span 85 by a two-step emulsification method., K. Kato, P. Walde, K. Akiyama and T. Sugahara, J. Disper. Sci. Technol., 2006, [Refereed], 10.1080/01932690600859903
  • Immunostimulation effect of the fermented milk on human hybridomas and peripheral blood lymphocytes., T. Sugahara, K. Nakamoto and K. Hara, Animal Cell Technology: Basic & Applied Aspects, 2006
  • Preparation of cationic immunovesicles containing cationic peptide lipid for specific drug delivery to target cells., T. Sugahara, S. Kawashima, A. Oda, Y. Hisaeda and K. Kato, Cytotechnology, 2005, [Refereed], 0920-9069, 10.1007/s10616-005-3764-5
  • Gene transfection into HeLa cells by vesicles containing cationic peptide lipid., Y. Ohama, Y. Heike, T. Sugahara, K. Sakata, N. Yoshimura, Y. Hisaeda, M. Hosokawa, S. Takashima and K. Kato, Biosci. Biotechnol. Biochem., 2005, 0916-8451|1347-6947, 10.1271/bbb.69.1453
  • Immunostimulation effects of proteose-peptone component 3 fragment on human hybridomas and peripheral blood lymphocytes., T. Sugahara, H. Onda, Y. Shinohara, M. Horii, K. Akiyama, K. Nakamoto and K. Hara, Biochim. Biophys. Acta, 2005, [Refereed], 10.1016/j.bbagen.2005.05.008
  • First enantioselective synthesis of (-)- and (+)-virgatusin,tetra-substituted tetrahydrofuran lignan., S. Yamauchi, M. Okazaki, K. Akiyama, T. Sugahara, T. Kishida and T. Kashiwagi, Org. Biomol. Chem., 2005, 1477-0520, 10.1039/b501151e
  • Identification of a novel zebrafish SULT1 cytosolic sulfotransferase: cloning, expression, characterization, and developmental expression study., M.-Y. Liu, Y.-S. Yang, T. Sugahara, S. Yasuda and M.-C. Liu, Arch. Biochem. Biophys., 2005, [Refereed], 0003-9861, 10.1016/j.abb.2005.02.029
  • Specific targeting at ERM5-1 cell as a model human-brain tumor cell and the anti-tumor effect by using immunovesicles., K. Kato, T. Manabe, T. Sugahara, K. Akiyama, Y. Omokawa, N. Kamata and H. Yamazaki, Congress Proceedings of 10th The Asian Pacific Confederation of Chemical Engineering Congress, 2004
  • Anti-cancer effect to colon cancer in either vitro or vivo using lipid vesicle combined with alga lectin ESA., K. Kato, Y. Omokawa, K. Akiyama, T. Sugahara, A. Kawakubo and T. Saeki, Congress Proceedings of 10th The Asian Pacific Confederation of Chemical Engineering Congress, 2004
  • Lactate dehydrogenase enhances immunoglobulin production by human hybridoma and human peripheral blood lymphocytes., S. Takenouchi and T. Sugahara, Cytotechnology, 2003, [Refereed], 0920-9069, 10.1023/B:CYTO.0000015838.06536.de
  • Sulphonation of dehydroepiandrosterone and neurosteroids: molecular cloning, expression, and functional characterization of a novel zebrafish SULT2 cytosolic sulphotransferase., T. Sugahara, Y.S. Yang, C.-C. Liu, T.G. Pai and M.-C. Liu, Biochem. J., 2003, [Refereed], 0264-6021, 10.1042/BJ20031050
  • Sulfonation of environmental estrogens by zebrafish cytosolic sulfotransferases., K. Ohkimoto, T. Sugahara, Y. Sakakibara, M. Suiko, M.-Y. Liu, G. Carter and M.-C. Liu, Biochem. Biophys. Res. Commun., 2003, [Refereed], 0006-291X, 10.1016/S0006-291X(03)01524-9
  • Sulfation of hydroxychlorobiphenyls: molecular cloning, expression, and functional characterization of zebrafish SULT1 sulfotransferases., T. Sugahara, C.-C. Liu, T.G. Pai, P. Collodi, M. Suiko, Y. Sakakibara, K. Nishiyama and M.-C. Liu, Eur. J. Biochem., 2003, [Refereed], 0014-2956, 10.1046/j.1432-1033.2003.03608.x
  • cDNA cloning, expression, and functional characterization of a zebrafish SULT1 cytosolic sulfotransferase., T. Sugahara, C.-C. Liu, G. Carter, T.G. Pai and M.-C. Liu, Arch. Biochem. Biophys., 2003, [Refereed], 0003-9861, 10.1016/S0003-9861(03)00172-3
  • High IgM production by human-human hybridoma HB4C5 cells cultured in microtubes., T. Sugahara, S. Yano and T. Sasaki, Biosci. Biotechnol. Biochem., 2003, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.67.393
  • Differential roles of human monoamine (M)-form and simple phenol (P)-form phenol sulfotransferases in drug metabolism., T. Sugahara, T.G. Pai, M. Suiko, Y. Sakakibara and M.-C. Liu, J. Biochem.-Tokyo, 2003, [Refereed], 0021-924X|1756-2651, 10.1093/jb/mvg033
  • Molecular cloning, expression, and functional characterization of a novel zebrafish cytosolic sulfotransferase., T. Sugahara, C.-C. Liu, T.G. Pai and M.-C. Liu, Biochem. Biophys. Res. Commun., 2003, [Refereed], 0006-291X, 10.1016/S0006-291X(02)02915-7
  • Structure-function relationships in the stereospecific and manganese-dependent 3,4-dihydroxyphenylalanine/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase, SULT1A3., T.G. Pai, I. Oxendine, T. Sugahara, M. Suiko, Y. Sakakibara and M.-C. Liu, J. Biol. Chem., 2003, [Refereed], 0021-9258, 10.1074/jbc.M203108200
  • Manganese stimulation and stereospecificity of the Dopa (3,4-dihydroxyphenylalanine)/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase. Kinetic studies of the mechanism using wild-type and mutant enzymes., T.G. Pai, K. Ohkimoto, Y. Sakakibara, M. Suiko, T. Sugahara and M.-C. Liu, J. Biol. Chem., 2002, [Refereed], 0021-9258, 10.1074/jbc.M200785200
  • Increase of immunoglobulin productivity of human-human hybridoma HB4C5 cells by histone., T. Okamoto, T. Sugahara, H. Tachibana and K. Yamada, Biosci. Biotechnol. Biochem., 2002, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.66.1241
  • Differential xenoestrogen-sulfating activities of the human cytosolic sulfotransferases: molecular cloning, expression, and purification of human SULT2B1a and SULT2B1b sulfotransferases., T.G. Pai, T. Sugahara, M. Suiko, Y. Sakakibara, F. Xu and M.-C. Liu, Biochim. Biophys. Acta, 2002, [Refereed], 10.1016/S0304-4165(02)00416-6
  • Heat denaturation enhanced immunoglobulin production stimulating activity of lysozyme from hen egg white., T. Sugahara, Y. Yamada, S. Yano and T. Sasaki, Biochim. Biophys. Acta, 2002, [Refereed], 10.1016/S0304-4165(02)00272-6
  • The cytotoxic effect of Eucheuma serra agglutinin (ESA) on cancer cells and its application to molecular probe for drug delivery system using lipid vesicles., T. Sugahara, Y. Ohama, A. Fukuda, M. Hayashi, A. Kawakubo and K. Kato, Cytotechnology, 2001, [Refereed], 0920-9069, 10.1023/A:1014057407251
  • Immunoglobulin production stimulating activity of heat-denatured lysozyme., T. Sugahara, Y. Yamada, Y. Ueda, S. Matsubara and T. Sasaki, Animal Cell Technology: Basic & Applied Aspects, 2001
  • Alcohol dehydrogenase-I from horse liver serves as an immunoglobulin production stimulating factor., OKAMOTO T, FURUTANI H, SASAKI T, SUGAHARA T, Enzyme Microb. Technol., 2001, 0141-0229, 10.1016/S0141-0229(01)00371-4
  • Application of the lipid vesicle immobilized Eucheuma serra lectin for target-specific drug delivery., T. Sugahara, K. Kato, A. Fukuda, A. Yoshihiro, N. Yohimura, N. Tateishi, and A. Kawakubo, Proc. of Biotechnology 2000 (The World Congress on Biotechnology), 2000
  • Preparation of an immunovesicle for specific combining to target cells toward either DDS or gene transfection., K. Kato, T. Sugahara, S. Kawashima, Y. Hayashi, A. Oda, Y. Hisaeda, T. Hayashi and T. Sasaki, Proc. of Biotechnology 2000 (The World Congress on Biotechnology), 2000
  • The mode of actions of lysozyme as an immunoglobulin production stimulating factor., T. Sugahara, F. Murakami, Y. Yamada and T. Sasaki, Biochim. Biophys. Acta, 2000, [Refereed], 10.1016/S0304-4165(00)00041-6
  • Study of the specific binding between lipid vesicles and human-human hybridoma toward either DDS or gene transfection., K. Kato, T. Sugahara, S. Kawashima, Y. Hayashi, A. Yoshihiro and T. Sasaki, Animal Cell Technology: Products from Cells, Cells as Products, 1999
  • Study of DDS for cancer therapy applying lipid vesicle immobilizing Eucheuma Serra lectin., K. Kato, T. Sugahara, Y. Maruyama, N. Yoshimura, A. Yoshihiro, N. Tateishi, Y. Suzuki, A. Kawakubo and T. Sasaki, Animal Cell Technology: Products from Cells, Cells as Products, 1999, [Refereed]
  • Effects of DNA on immunoglobulin production stimulating activity of alcohol dehydrogenase., T. Okamoto, H. Furutani, T. Sasaki and T. Sugahara, Cytotechnology, 1999, [Refereed], 0920-9069, 10.1023/A:1008024322602
  • The mode of actions of lysozyme as an immunoglobulin production stimulating factor (IPSF)., T. Sugahara, F. Murakami and T. Sasaki, Animal Cell Technology: Products from Cells, Cells as Products, 1999
  • Aldolase from rabbit muscle enhances immunoglobulin production by human hybridoma and human peripheral blood lymphocytes., T. Sugahara, F. Moriya, H. Myoga, T. Uchiyama and T. Sasaki, Enzyme Microb. Technol., 1999, [Refereed], 0141-0229, 10.1016/S0141-0229(98)00087-8
  • Inhibition of immunoglobulin production stimulating activity of glyceraldehyde-3-phosphate dehydrogenase by nucleotides., T. Sugahara and T. Sasaki, Biosci. Biotechnol. Biochem., 1998, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.62.1237
  • A novel function of enolase from rabbit muscle; an immunoglobulin production stimulating factor., T. Sugahara, S. Shimizu, M. Abiru, S. Matsuoka and T. Sasaki, Biochim. Biophys. Acta, 1998, [Refereed], 10.1016/S0304-4165(97)00137-2
  • Spermine enhances IgM productivity of human-human hybridoma HB4C5 cells and human peripheral blood lymphocytes., Y. Miyazaki, S. Nishimoto, T. Sasaki and T. Sugahara, Cytotechnology, 1998, [Refereed], 0920-9069, 10.1023/A:1007939213564
  • Enhancement of immunoglobulin production of hybridomas and lymphocytes by alcohol dehydrogenase-I., T. Sugahara, H. Furutani, F. Murakami, S. Shimizu, F. Moriya, Y. Miyazaki, S. Nishimoto and T. Sasaki, Biochemical Engineering: Marching Toward The Century of Biotechnology, 1997
  • Alcohol dehydrogenase-I from horse liver stimulates immunoglobulin production by human hybridoma and human peripheral blood lymphocytes., T. Sugahara, H. Furutani and T. Sasaki, Mol. Cell. Biochem., 1997, [Refereed]
  • Immunoglobulin production stimulating activities of basic proteins., T. Sugahara, M. Fujisawa, S. Matsuoka, F. Murakami, H. Furutani, M. Abiru, T. Uchiyama and T. Sasaki, Animal Cell Technology: Basic & Applied Aspects, 1997
  • Lysozyme stimulates immunoglobulin production by human-human hybridoma and human peripheral blood lymphocytes., F. Murakami, T. Sasaki and T. Sugahara, Cytotechnology, 1997, [Refereed], 10.1023/A:1007936629501
  • Enhancement of IgM production of human peripheral blood lymphocytes by rice fermented seasoning under serum-free cultivation., T. Sugahara, K. Fukaya and T. Sasaki, J. Ferment. Bioeng., 1996, [Refereed], 0922-338X, 10.1016/0922-338X(96)89459-1
  • Effects of sodium poly(styrene sulfonate) on antibody production and cell growth HB4C5 hybridoma cells., K. Nagira, M. Hayashida, M. Shiga, K. Sasamoto, K. Kina, K. Osada, T. Sugahara, T. Hara, Y. Yamamoto and H. Murakami, Polym. J., 1995, [Refereed], 0032-3896|1349-0540, 10.1295/polymj.27.719
  • Immunoglobulin production stimulating activities of nucleic acid-binding proteins., T. Sugahara, S. Shirahata, T. Sasaki and H. Murakami, Animal Cell Technology: Developments towards the 21st Century, 1995
  • Effects of organic pH buffers on cell growth and antibody production of human-human hybridoma HB4C5 cells in a serum-free culture., K. Nagira, M. Hayashida, K. Sasamoto, K. Kina, K. Osada, T. Sugahara and H. Murakami, Cytotechnology, 1995, [Refereed], 0920-9069, 10.1007/BF00749399
  • The mode of actions of glyceraldehyde-3-phosphate dehydrogenase identified as an immunoglobulin production stimulating factor, T. Sugahara, S. Shirahata, T. Sasaki and H. Murakami, FEBS Letters, 1995, [Refereed], 0014-5793, 10.1016/0014-5793(95)00607-B
  • Removability and permeability of DNA in protein solution using BMM., T. Hirasaki, K. Yamaguchi, A. Kono, T. Noda, T. Sugahara, N. Yamamoto and H. Murakami, Animal Cell Technology: Basic & Applied Aspects, 1994
  • Synthesis of bis-piperazine-type pH buffer agents and their application to mammalian cell cultures., K. Nagira, M. Shiga, K. Sasamoto, K. Kina, M. Hayashida, T. Sugahara and H. Murakami, Biosci. Biotechnol. Biochem., 1994, [Refereed], 0916-8451|1347-6947, 10.1271/bbb.58.1370
  • Enhancement of immunoglobulin productivity of human-human hybridoma HB4C5 cells by basic proteins and poly-basic amino acids., T. Sugahara, T. Sasaki and H. Murakami, Biosci. Biotechnol. Biochem., 1994, [Refereed], 10.1271/bbb.58.2212
  • Immunoglobulin production stimulating factors., H. Murakami, T. Sugahara and H. Nakajima, Cell Biology and Biotechnology: Novel Approaches to Increased Cellular Productivity, 1993
  • Immunoglobulin production stimulating factor (IPSF) derived from Namalwa cells., T. Sugahara, H. Nakajima, S. Shirahata, K. Nagamine and Murakami, Animal Cell Technology: Basic & Applied Aspects, 1993
  • Serum-free culture of human-human hybridoma secreting monoclonal antibody against stomach cancer., A.M. Ali, M. Hayashida, T. Sugahara, K. Akiyama, M.M. Dahan and H. Murakami, Animal Cell Technology: Basic & Applied Aspects, 1992
  • Virus containment continuous culture of animal cells., T. Sugahara, T. Noda, T. Tsuboi, T. Hirasaki, N. Yamamoto, S. Sakaeda and H. Murakami, Animal Cell Technology: Basic & Applied Aspects, 1992
  • Purification and characterization of immunoglobulin production stimulating factor-IIβ derived from Namalwa cells., T. Sugahara, H. Nakajima, S. Shirahata and H. Murakami, Cytotechnology, 1992, [Refereed], 0920-9069, 10.1007/BF00570890
  • Purification and characterization of immunoglobulin production stimulating factor IIα derived from Namalwa cells., H. Murakami, T. Sugahara, S. Shirahata and K. Yamada, Production of Biologicals from Animal Cells in Culture, 1991
  • Immunoglobulin production stimulating factor-IIα (IPSF-IIα) is glyceraldehyde-3-phosphate dehydrogenase like protein., T. Sugahara, S. Shirahata, K. Akiyoshi, T. Isobe, T. Okuyama and H. Murakami, Cytotechnology, 1991, [Refereed], 0920-9069, 10.1007/BF00373028
  • Large-scale, high-density freezing of hybridomas and its application to high-density culture., N. Ninomiya, T. Sugahara, S. Shirahata and H. Murakami, Biotechnol. Bioeng., 1991, [Refereed], 0006-3592, 10.1002/bit.260380920
  • Purification of immunoglobulin production stimulating factor IIα derived from Namalwa cells., T. Sugahara, S. Shirahata, K. Yamada and H. Murakami, Cytotechnology, 1991, 0920-9069, 10.1007/BF00556295
  • Enhancement of immunoglobulin production of human-human hybridomas by immunoglobulin production stimulating factors., Trends in Animal Cell Culture Technology, 1990
  • Relationship between oxygen consumption rate and cellular activity of mammalian cells culturedin serum-free media., K. Yamada, S. Furushou, T. Sugahara, S. Shirahata and H. Murakami, Biotechnol. Bioeng., 1990, [Refereed], 0006-3592, 10.1002/bit.260360715
  • Purification and characterization of immunoglobulin production stimulating factor derived from human B lymphoblastoid HO-323 cells., K. Toyoda, T. Sugahara, K. Inouye, K. Yamada, S. Shirahata and H. Murakami, Cytotechnology, 1990, [Refereed]
  • Stimulation of proliferation and immunoglobulin M production by lactoferrin in human-human and mouse-mouse hybridomas cultures in serum-free conditions., K. Yamada, I. Ikeda, T. Sugahara, S. Hashizume, S. Shirahata and H. Murakami, Cytotechnology, 1990, [Refereed]
  • Screening of immunoglobulin production stimulating factor (IPSF) in foodstuffs using human-human hybridoma HB4C5 cells., K. Yamada, I. Ikeda, T. Sugahara, S. Shirahata and H. Murakami, Agric. Biol. Chem., 1989, [Refereed], 0002-1369|1881-1280, 10.1271/bbb1961.53.2987
  • Stimulation of monoclonal antibody production by human-human hybridoma cells with an elevated concentration of potassium or sodium phosphate in serum-free medium., S. Sato, H. Murakami, T. Sugahara, T. Ikegami, K. Yamada, H. Omura and S. Hashizume, Cytotechnology, 1989, [Refereed]
  • Partial purification and characterization of immunoglobulin production stimulating factor derived from Namalwa cells., K. Yamada, K. Akiyoshi, H. Murakami, T. Sugahara, I. Ikeda, K. Toyoda and H. Omura, In Vitro Cell. Develop. Biol., 1989, [Refereed]

Books etc

Conference Activities & Talks

  • Health functions of Indonesian local products., Sugahara T., General Lecture, 2019/08, 招待有り
  • Anti-inflammatory effect of citrus peel., Sugahara T., Ishida M., Takekuni C., Nishi K., 9th International Conference on Traditional and Complementary Medicine (9th INTRACOM), 2019/08, 招待有り
  • Health function of cumin seed., Sugahara T., Seminar National Teknologi Pandan dan Hasil Pertanian 2019, 2019/08, 招待有り
  • 2019/07
  • 2019/07
  • 2019/07
  • 2019/07
  • Studies on anti-degranulation activity of caffeine., Nugrahini A.D., Ishida M., Nishi K. and Sugahara T., 2019/06
  • 2019/06
  • 2019/06
  • 2019/03
  • 2019/03
  • 2019/01, 招待有り
  • Anti-allergy effect of nobiletin from citrus peel and development of functional food, Sugahara T., Nishi K., Ishida M., 9th International Conference on Nutrition and Physical Activity (NAPA 2018), 2018/12, 招待有り
  • 2018/12, 招待有り
  • Anti-metabolic syndrome activity of flaxseed lignan., Sugahara T., ASEAN - Japan Network for Transdisciplinary Research and Practice for Reducing Environmental Problems (TRPNEP2018), 2018/12, 招待有り
  • Development of functional foods., Sugahara T., ASEAN - Japan Network for Transdisciplinary Research and Practice for Reducing Environmental Problems (TRPNEP2018), 2018/12, 招待有り
  • 2018/12, 招待有り
  • 2018/11
  • Anti-allergic effect of citrus component and development of functional foods, Sugahara T., Functional food: Potency, reseach and commercialutilization, 2018/11, 招待有り
  • 2018/10
  • Anti-allergic effect of water-soluble extract of cumin seeds., Hada M, Ishida M., Onda H., Nishimoto S., Nishi K., Sugahara T., The 11th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2018), 2018/10
  • Effect of lysozyme on lipopolysaccharide-induced inflammation model mice., Tagashira A., Nishi K., Matsumoto S., Sugahara T., ISNFF2018, 2018/10
  • Evaluation of food functions., Sugahara T., Udayana University, Guest lecture, 2018/09, 招待有り
  • Health function of citrus and development of functional foods., Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 2018/09, 招待有り
  • Immature black vinegar extract activates macrophages., Ishii E., Nishi K., Ishida M., Nagano M., Hashiguchi K., Fujii A. Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 2018/09
  • Anti-inflammatory effect of placenta water-soluble extract on macrophages., Yokotani M., Nishi K., Sasaki Y. and Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 2018/09
  • Anti-allergic effect of clove., Murielle D.T.A., Ishida M. Onda H., Nishi K. and Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 2018/09
  • Anti-inflammatory effect of aqueous extract from Kawachi-bankan peel on lipopolysaccharide-induced inflammatory responses in RAW264.7 cells., Ishida M., Takekuni C., Nishi K., Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 2018/09
  • Anti-inflammatory effect of lysozyme from hen egg white., Tagashira A., Nishi K., Matsumoto S. and Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 2018/09
  • Inhibitory effect of caffeine on degranulation of RBL-2H3 cells., Nugrahini A.D., Ishida M., Nishi K. and Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 2018/09
  • Functional foods in Japan., Sugahara T., Gadjah Mada University Guest lecture, 2018/08, 招待有り
  • 2018/08, 招待有り
  • Health functions of Indonesian local crops., Sugahara T., Airlangga University Seminar, 2018/08, 招待有り
  • The suppressive effect of tropical fruits on IgE production., Sugahara T., Recent trends and future prespectives on functional food ingredients, 2018/08, 招待有り
  • Anti-metabolic syndrome activity of foods., Sugahara T., 2018/08, 招待有り
  • Health functions of Indonesian local crops., Sugahara T., Seminr National, 2018/07, 招待有り
  • 2018/06
  • The suppressive effect of ethanol extract from passion fruit seeds on IgE production, Sugahara T., Mizusaki A., Nishi K., HiSEA 2018, Opportunities in Developing & Implementing Sustainable Functional Foods and Nutraceuticals, 2018/03, 招待有り
  • 2018/03
  • Evaluation of food functions and development of functional foods. - Anti-allergic effect of citrus -., Sugahara T., General lecture, Hasanuddin University., 2017/11, 招待有り
  • 2017/11, 招待有り
  • 2017/11, 招待有り
  • Suppressive effect of ethanol extract from mango (Mangifera indica L.) peel on IgE production in vitro and in vivo., Ishida M., Sasaki T., Nishi K., Tamamoto T., Sugahara T., The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), 2017/10
  • Anti-inflammatory effect of lysozyme from hen egg white on macrophages., Tagashira A., Nishi K., Mastumoto S., Sugahara T., The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), 2017/10
  • Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells., Sugahara T., Domen M., Yasunaga S., Nishi K., Ishida M., Kadota A., The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), 2017/10
  • Anti-allergic effect of Coriandrum sativum L. leaf extract., Kitamura Y., Ishida M., Onda H., Nishimoto S., Nishi K., Sugahara T., The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), 2017/10
  • 2017/10, 招待有り
  • Development of functional foods based on health function research on foods. - Anti-allergic effect of citrus -., Sugahara T., Guest lecture, Widya Mandala Catholic University, 2017/09, 招待有り
  • 2017/09
  • 2017/09
  • 2017/09
  • Evaluation of food functions and development of functional foods.,, Sugahara T., Guest lecture, Ahmad Dahlan University, 2017/08, 招待有り
  • Evaluation of food functions and development of functional foods., Sugahara T., Focus Group Discussion on International Collaborative Research, Jember University, 2017/08, 招待有り
  • Health Functions of Indonesian Local Crops., Sugahara T., Focus Group Discussion on International Collaborative Research, Jember University, 2017/08, 招待有り
  • 2017/07
  • 2017/07
  • 2017/07
  • 2017/07
  • 2017/07
  • 2017/07
  • 2017/07
  • 2017/06, 招待有り
  • 2017/05
  • 2017/05
  • Functional foods with the anti-allergy activity., SUGAHARA Takuya, Health Ingredients South East Asia -International Conference on Revitalising & Repositioning Functional Foods and Neutraceuticals as Essential Indicator of Wellness., 2017/03, 招待有り
  • 2017/03
  • 2017/03
  • 2017/03
  • 2017/02, 招待有り
  • 2017/02
  • 2017/01
  • Immunostimulatory effect of jellyfish collagen., Sugahara T., Workshop on Food Function, 2016/12
  • 2016/12, 招待有り
  • Academic writing and publishing for international journals., Sugahara T., University of Pembangunan Nasional “Veteran” Jawa Timur, 2016/12, 招待有り
  • The suppressive effect of ethanol extract from passion fruit seeds on IgE production., Mizusaki Ai, Nishi K. and Sugahara T., The 29th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2016), 2016/11
  • Anti-allergic effect of Awabancha-tea., Inoue E., Kondo M., Nishi K. and Sugahara T., The 29th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2016), 2016/11
  • Functional Foods with the antiallergy activity., Nishi K. and Sugahara T., The 29th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2016), 2016/11, 招待有り
  • Effect of major spice extracts on response of mammalian immune cells., Nishimoto S., Sasaki A., Onda H. and Sugahara T., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 2016/10
  • Immunostimulatory effect of dried coriander seed extract on mouse macrophage-like RAW264.7 cells and mouse peritoneal macrophages., Onda H., Kunihiro N., Ishida M., Nishi K. and Sugahara T., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 2016/10
  • Effects of 3-phenylamino-L-alanine (PAA) and 4-aminophenol (4-AP) on chemotaxis and expression of chemokine receptors in human eosinophils., Tagashira A., Okamoto T., Yamauchi A., Nakano K., Nishi K. and Sugahara T., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 2016/10
  • Immunostimulatory effect of dried bonito extract on mouse macrophage-like J774.1 cells and mouse peritoneal macrophages., Ishida M., Shinohara K., Kunihiro N., Nishi K., Osajima K., Suemitsu K. and Sugahara T., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 2016/10
  • Effect of lysozyme on RAW264.7 cells stimulated by lipopolysaccharide., Sugahara T., Matsumoto S. and Nishi K., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 2016/10
  • 2016/10, 招待有り
  • The development of functional foods: from bench to mass production., Sugahara T., Indonesia International Institute for Life Science , 2016/09, 招待有り
  • 2016/09, 招待有り
  • 2016/09
  • 2016/09
  • 2016/09
  • 2016/09
  • 2016/09
  • 2016/08, 招待有り
  • 2016/07, 招待有り
  • 2016/05
  • 2016/05, 招待有り
  • 2016/03
  • 2016/03
  • 2016/03
  • 2016/03
  • Anti-allergic function of microbial-fermented tea, Ishiduchi black tea, Sugahara T., Kondo M. and Nishi K., 国際シンポジウム 発酵茶に関する複合領域的研究, 2016/03, 招待有り
  • 2016/02
  • Anti-allergic function of microbial-fermented tea in Ehime, Japan., SUGAHARA Takuya, i3L Half-day Food Science Seminar, 2015/12, 招待有り
  • 2015/11
  • Anti-allergic effect of a microbial-fermented tea, Ishizuchi dark tea., Sugahara T., Kondo M., Ishida M. and Nishi K., The 6th International Conference on Food Factors (ICoFF 2015), 2015/11
  • 2015/11, 招待有り
  • 2015/11
  • Immunological functions of bengkoang fiber extracts., Sugahara T., The second International Conference on Agro-industry (ICoA 2015), 2015/11, 招待有り
  • Health functions of Indonesian local crops: insight from biomolecular perspective., Sugahara T., i3L Power Talk, 2015/10, 招待有り
  • Immunostimulatory effect of jellyfish collagen., Sugahara T., Putra A.B.N., Nishi K. and Doi M., Bali International Seminar on Science and Technology (BISSTECH 3 2015) (October 15-16, Bali, Indonesia), 2015/10, 招待有り
  • Effect of bengkoang (Pachyrhizus erosus) fiber extract on murine macrophage-like J774.1 cells and mouse peritoneal macrophages., Sugahara T., Kumalasari I.D., Nishi K. and Putra A.B.N., 7th International Conference and Exhibition on Nutraceuticals and Functional Foods (ISNFF 2014), 2015/10
  • Anti-allergic function of microbial-fermented tea produced in Ehime, Japan., Sugahara T., Kondo M., Putra A.B.N. and Nishi K., Bali International Seminar on Science and Technology II 2014 (BISSTECH 2014), 2015/09, 招待有り
  • Studies on the stimulatory effects of jellyfish collagen on innate immune system., Sugahara T., The 3rd Third International Conference on Sustainable Agriculture and Natural Recourses Management, 2015/08, 招待有り
  • Health function of lignan from flaxseeds., Sugahara T., 12th Asian Congress of Nutrition (ACN2015), 2015/05, 招待有り
  • 2015/02, 招待有り
  • 2014/12
  • 2014/11, 招待有り
  • Immunological functions of Indonesian local crops., Sugahara T., Synergy of Food, Feed, and Renewable Energy 2014 (SPRINT 2014), 2014/10, 招待有り
  • Immunological functions of Indonesian local crops., Sugahara T., University of Pembangunan Nasional Veteran East Java, 2014/09, 招待有り
  • 2013/12
  • 2013/11
  • 2013/07
  • Studies on immunotoxicity of o-phenylphenol (OPP) and metabolite., Sugahara T., Nakata Y., Nishi K. and Nishimoto S., The 25th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2012), 2012/11
  • 2012/11, 招待有り
  • Effect of flaxseed lignan on lipid accumulation in adipocytes., Sugahara T., Tominaga S., Yamauchi S., Nishimoto S. and Nishi K., International Conference on Food Factors (ICoFF) 2011, 2011/11
  • Effect of secoisolariciresinol on adipogenesis., Sugahara T., Tominaga S., Yamauchi S., Maruyama M., The 14th International Biotechnology Symposium and Exhibition (IBS2010), 2011/09
  • Effects of endosulfan on allergic response., Sugahara T., Nishimoto S., Atobe S., Hosoba K., Okabe M. and Kakinuma Y., The 23rd Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2010), 2011/09
  • Evaluation of food functions by animal cell culture and experimental animals., Sugahara T., Nishi K. and Nishimoto S., Gadjah Mada-Ehime Network (GEN) 2010, 2011/08
  • Anti-cancer effect of lectin from red sea alga., Sugahara T., Tominaga S., Yamauchi S., Nishimoto S. and Nishi K., The 2nd International Symposium on Temulawak, 2011/05, 招待有り

Works

  • 2017 -
  • 2004 - 2005
  • 2005 - 2006
  • 2005 - 2006
  • 2005 - 2006
  • 2005 - 2005
  • 2006 - 2006
  • 2006 - 2006
  • 2005 - 2008
  • 2007 - 2007
  • 2007 - 2007
  • 2008 - 2008
  • 2009 - 2009
  • 2008 - 2009
  • 2008 - 2008
  • 2008 - 2008
  • 2009 - 2009
  • 2008 - 2008
  • 2008 - 2010
  • 2009 - 2011
  • 2009 - 2010
  • 2009 - 2009
  • 2009 - 2010
  • 2010 - 2010
  • 2010 - 2010
  • 2010 - 2010
  • 2010 - 2010
  • 2010 - 2010
  • 2011 - 2011
  • ホワイトソルガムの生理機能評価に関する研究, 2005 - 2006
  • 発酵乳の免疫調節活性に関する研究, 2005 - 2005

Misc

  • 30, 322, 2019/03
  • 37, 3, 33, 36, 2019/03
  • 74, 2, 1, 1, 2019/02
  • 452, 1, 22, 23, 2019/01
  • 22, 7, 47, 49, 2018/07
  • 36, 2, 94, 98, 2018/02
  • 14, 9, 161, 161, 2017/09
  • 14, 9, 160, 161, 2017/09
  • 10, 6, 354, 359, 2017/06
  • 28, 9, 63, 64, 2017/05
  • 96, 3, 190, 193, 2017/03
  • 22, 2, 56, 58, 2017/02
  • 51, 10, 64, 66, 2016/10
  • 45, 10, 42, 45, 2016/10
  • 58, 60, 2016/10
  • 3, 8, 35, 40, 2015/08
  • 19, 8, 38, 41, 2015/08
  • 19, 1, 1, 6, 2015
  • 49, 3, 30, 33, 2013/03
  • 17, 1, 13, 19, 2013
  • 59, 11, 556, 561, 2012/12, 10.3136/nskkk.59.556
  • 16, 2, 45, 47, 2012/02
  • 15, 1, 24, 30, 2011
  • 22, 8, 60, 63, 2009/08
  • 55, 184, 187, 2007, 10.20665/kakyoshi.55.4_184
  • 6, 25, 31, 2002
  • 230, 238, 2001
  • 74, 10, 1107, 1112, 2000/10, 0002-1407|1883-6844, 10.1271/nogeikagaku1924.74.1107
  • 74, 9, 986, 989, 2000, 0002-1407|1883-6844, 10.1271/nogeikagaku1924.74.986
  • 45, 457, 463, 2000
  • 2, 18, 23, 1998
  • 2, 60, 64, 1998
  • 70, 801, 802, 1996

Other Research Activities

Patents

  • 免疫賦活組成物及び免疫賦活用食品組成物, 特願2017-139846
  • 抗アレルギー剤, 菅原卓也、恩田浩幸, 特願2017-070071
  • 免疫賦活剤及び免疫不活用食品組成物, 西本壮吾、恩田浩幸、菅原卓也, 特願2017-039645
  • 特願2016-179217
  • 特願2016-085996, 特開2016-169219, 特許第6113325号
  • アレルギー症状緩和剤, 菅原卓也、筬島克裕、近藤智彦、末光友和, 特願2015-202449, 特開2017-075104
  • マクロファージ活性化剤, 菅原卓也、筬島克裕、近藤智彦、末光友和, 特願2015-202454, 特開2017-075105
  • 脱顆粒抑制剤, 菅原卓也、長野正信、橋口和典、藤井 暁, 特願2015-176262, 特開2017-052710
  • マクロファージの活性促進剤および脱顆粒抑制剤, 菅原卓也、長野正信、橋口和典、藤井 暁, 特願2015-176263, 特開2017-052711
  • 特願2013-168073, 特開2015-036369, 特許第6000206号
  • 特願2013-134918, 特開2015-010041
  • 特願2009-22058
  • 特願2007-51746, 特開2008-212026
  • 特許第4656300号
  • 特許第5177468号
  • 特許第4974020号
  • 特許第4888687号
  • 特許第5137098号
  • 特許第4688457号
  • 特願2003-338777, 特開2005-068120
  • 特許第4928689号
  • 特願2001-190515, 特開2003-012503
  • 特願平11-369959, 特開2001-181213
  • 特願2008-223010, 特開2010-057367
  • 特願2009-015059, 特開2010-173937
  • 特願2009-230906, 特開2010-116391
  • 特願2010-046709, 特開2011-178750
  • 特願2011-202216, 特開2013-231679, 特許第5981114号
  • 特願2010-260076, 特開2012-111698
  • 特願2011-021257, 特開2012-157338
  • 特願2011-043850, 特開2012-180303
  • 特願2011-100261, 特開2012-231679
  • 特願2010-160104, 特開2011-116735, 特許第5688697号

Awards & Honors

  • 2017/07, 日本動物細胞工学会2017年度大会(JAACT2017), JAACT2017 Postar award
  • 2016/11
  • 2016/11
  • 2015/03
  • 2011/11, International Conference on Food Factors (ICoFF) 2011, Poster Award, Effect of flaxseed lignan on lipid accumulation in adipocytes.
  • 2000/03
  • 2017/10, 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), ISNFF2017 Poster Award, Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells.


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