Researchers Database

UNO, Hidemitsu

    Ehime University Executive Director
Last Updated :2020/10/13

Researcher Information

Degree

  • Dr of Science(Kyoto University)

J-Global ID

Research Interests

  • ペリ環状分解反応   クムレン   フロリン   ポルフィリン   分子認識   近赤外色素   ヘキサフィリン   BODIPY   テトラチオシン   消耗性電極   構造有機化学   ピロロイソインドール   硫黄炭素混合電極   グルタミン酸   テトラベンゾポルフィリン   有機電子材料   ペンタチエピン   ボロンジピロメテン   ビニルスルフィド   トリフルオロメチル基   ペンタセン   ポルフィリノイド   逆Diels-Alder反応   高共役化合物   キレトロピー分解反応   ポルフィリシ   構造解析   SS43405E   共役拡張ポルフィリノイド   AH-1763 IIa   コロネン   ペリ環状反応   有機合成   有機化学   色素フィルター   抗ウイルス剤   抗生物質   有機発光ダイオード   有機トランジスタ   有機太陽電池   Coronene   Pentacene   Porphyrinoid   retro-Diels-Alder reaction   pericyclic reaction   Highly conjugated compounds   Organic synthesis   Organic chemistry   Color filter   Antivirus   Antibiotics   Organic light emitting diode   Organic transistor   Organic solar cell   

Research Areas

  • Manufacturing technology (mechanical, electrical/electronic, chemical engineering) / Electronic devices and equipment
  • Life sciences / Bioorganic chemistry
  • Nanotechnology/Materials / Structural/physical organic chemistry
  • Nanotechnology/Materials / Functional solid-state chemistry
  • Nanotechnology/Materials / Synthetic organic chemistry

Academic & Professional Experience

  • 2015/04 - Today  Ehime UniversityExecutive Director and Vice President
  • 2009 - Today  Ehime University大学院・理工学研究科教授
  • 2013/04 - 2015/03  Ehime UniversityFaculty of ScienceDean
  • 2012/04 - 2013/03  Ehime UniversityFaculty of ScienceVice Dean
  • 2008/08 - 2011/03  Kyushu UniversityInstitute for Materials Chemistry and EngineeringSpecially-appointed Professor
  • 2008/04 - 2011/03  The Open University of JapanEhime Study CenterVisiting Professor
  • 2008 - 2011  University of Air
  • 2003/04 - 2009/03  Ehime UniversityIntegrated Center for SciencesProfessor
  • 2003 - 2009  Integrated Center for Sciences, Ehime University
  • 2009  - Department of Chemistry and Biology, Graduate School of Science and Engineering, Ehime University
  • 2006/04 - 2008/03  Ehime UniversityTrustee
  • 2008  - Institute for Materials Chemistry and Engineering, Kyushu University
  • 2005/04 - 2006/03  Kyushu UniversityInstitute for Materials Chemistry and EngineeringPart-time lecturer
  • 1989/06 - 2003/03  Ehime UniversityAdvanced Instrumentation Center for Chemical AnalysisAssociate professor
  • 2002 - 2003  The University of the Air
  • 1989 - 2003  Advanced Instrumentation Center for Chemical Analysis, Ehime University
  • 2002/04 - 2002/09  The Open University of JapanEhime Study CenterPart-time lecturer
  • 1984/06 - 1989/05  Ehime UniversityAdvanced Instrumentation Center for Chemical AnalysisAssistant professor
  • 1984 - 1989  Advanced Instrumentation Center for Chemical Analysis, Ehime University

Education

  • 1982/04 - 1984/05  Kyoto University  Graduate School of Science、Ph D  Department of Chemistry
  • 1980/04 - 1982/03  Kyoto University  Graduate School of Science  Department of Chemistry
  •        - 1982  Kyoto University  Graduate School, Division of Natural Science
  • 1976/04 - 1980/03  Kyoto University  Faculty of Science  Department of Chemistry

Association Memberships

  • Royal Society of Chemistry   臭素化学懇話会   光化学協会   ポルフィリン・フタロシアニン学会   国際複素環学会   電気化学協会   有機合成協会   日本化学会   Royal Society of Chemistry   Community of bromine application   Japanese Photochemistry Association   American Chemical Society   Society of Porphyrins and Phthalocyanines   International Society of Heterocyclic Chemistry   Electrochemical Society of Japan   Synthetic Organic Chemistry   Chemical Society of Japan   

Published Papers

  • Yoshiki Sasaki, Masayoshi Takase, Shigeki Mori, Hidemitsu Uno
    Molecules 25 (11) 2486 - 2486 2020/05 [Peer-reviewed]
     Scientific journal 
    Hexapyrrolohexaazacoronene (HPHAC) is one of the N-containing polycyclic aromatic hydrocarbons in which six pyrroles are fused circularly around a benzene. Despite the recent development of HPHAC analogues, there is no report on direct introduction of functional groups into the HPHAC skeleton. This work reports the first example of nitration reaction of decaethylHPHAC. The structures of nitrodecaethylHPHAC including neutral and two oxidized species (radical cation and dication), intramolecular charge transfer (ICT) character, and global aromaticity of the dication are discussed.
  • Hidemitsu Uno, Kota Muramatsu, Shogo Hiraoka, Hiroyuki Tahara, Mako Hirose, Eidai Tamura, Tatsumi Shiraishi, John Mack, Nagao Kobayashi, Shigeki Mori, Tetsuo Okujima, Masayoshi Takase
    Chemistry – A European Journal 26 (25) 5701 - 5708 0947-6539 2020/05 [Peer-reviewed]
     Scientific journal
  • Akio Kamimura, Tomoyuki Itaya, Tatsuro Yoshinaga, Ryo Nozawa, Takuji Kawamoto, Michinori Sumimoto, Hidemitsu Uno
    European Journal of Organic Chemistry 2020 (11) 1700 - 1707 1434-193X 2020/03 [Peer-reviewed]
     Scientific journal 
    © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Treatment of 1,6-azaeneyne compounds with Ph3SnH resulted in the stereoselective formation of 5-(E)-alkylidene-2,3-cis-piperidine in moderate to good yields. Intermediate products including methylenepyrrolidine and stannomethylene pyrrolidine were also detected in the reaction mixture, suggesting that the reaction progressed via a highly cumulated radical cascade process involving sequential six radical processes, i.e. radical addition, 5-exo cyclization, substitution (1,4-tin migration), 3-exo cyclization, ring cleavage of cycloprolane, and hydrogen abstraction from Ph3SnH. The product distribution depended on the lower Ph3SnH concentration, resulting in higher piperidine yields. The E/Z selectivity of the exo-methylene unit was also sensitive to the reaction temperature. The vinylic triphenyltin group was converted into hydrogen and iodine. A kinetic analysis of the reaction indicated that the 1,4-tin migration and ring expansion progressed as irreversible reactions and that their reaction rates were large enough to progress the cascade reaction smoothly and to prevent side reactions such as hydrogen abstraction from Ph3SnH.
  • Kosuke Oki, Masayoshi Takase, Shigeki Mori, Hidemitsu Uno
    Journal of the American Chemical Society 141 (41) 16255 - 16259 0002-7863 2019/10 [Peer-reviewed]
     Scientific journal 
    Copyright © 2019 American Chemical Society. An antiaromatic cation of the expanded hexapyrrolohexaazacoronene (HPHAC) 1+ was synthesized by a Vilsmeier-type reaction of the partially unfused HPHAC 2. X-ray diffraction analysis revealed the formation of a seven-membered ring with a methyne linkage between the pyrrole moieties. Although 1+ is a monocation, upfield shifts of the peripheral ethyl protons were clearly observed in the 1H NMR spectra, indicating 24πantiaromaticity. Global antiaromaticity was also supported by nucleus-independent chemical shift and anisotropy of the induced current density calculations. Cation 1+ displayed two reversible oxidations and one irreversible reduction in the cyclic voltammetry measurements. Treatment of 1+ with NOSbF6 gave aromatic trication 13+ with 22π-electron conjugation.
  • Taniyuki Furuyama, Tetsuo Okujima, Kota Muramatsu, Yuichi Takahashi, Akihiro Mikami, Tomoteru Fukumura, Shigeki Mori, Takahiro Nakae, Masayoshi Takase, Hidemitsu Uno, Nagao Kobayashi
    European Journal of Organic Chemistry 2019 (20) 3224 - 3235 1434-193X 2019/06 [Peer-reviewed]
     Scientific journal 
    © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim A series of free-base and phosphorus(V) complexes of tetrabenzoporphyrin (TBP) and some phosphorus(V) porphyrins containing four or eight phenyl groups on the periphery have been synthesized and characterized by X-ray crystallography, electronic absorption, and magnetic circular dichroism (MCD) spectroscopy, together with quantum chemical calculations. All phosphorus TBP and meso-tetraphenyl porphyrin complexes adapted ruffled conformations due to the small P(V) ion, although the Zn(II)TBPs containing eight phenyl (Φ) groups at the so-called β and α positions showed planar and saddled structures in the solid state, due to, respectively, marginal or severe steric hindrance between the neighboring Φ groups. All P(V)TBPs showed the Soret and Q bands beyond 450 and 700 nm, respectively, which are some of the longest wavelengths exhibited by metallated TBPs reported to date. Of the eight Φ group-substituted P(V)TBPs, those substituted at α positions always showed absorption bands at longer wavelengths than those at β positions, which was reproduced by calculated absorption spectra. The Soret band positions of meso-tetraphenylated P(V) species without fused benzo-groups (ca. 430–440 nm) were also some of the longest among metalloporphyrins of this type.
  • Shigeki Mori, Naoki Kawamoto, Hidemitsu Uno
    ChemPlusChem 84 (6) 686 - 693 2019/06 [Peer-reviewed]
     Scientific journal 
    © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Bis(bicyclic) molecules dimethanochrysene and diethanochrysene were prepared by Diels-Alder reaction of the naphthodiyne equivalent with cyclopentadiene and 1,3-cyclohexadiene, respectively. Reaction of dimethanochrysene and 7,9-diphenyl-8H-cyclopent[a]acenaphthylen-8-one resulted in the generation of a fluorescent hydrocarbon in unexpected multistep pericyclic reactions. Syn-oriented diethanochrysene-connected bisporphyrin tweezers was prepared from the reaction of chrysene-bridged syn-dipyrrole with tripyrranedicarbaldehyde. The structure of the receptor and its 1 : 1 complex with C60 or C70 was determined by X-ray diffraction analysis. The dihedral angles of the bicyclo[2.2.2]octadiene moieties were narrowed by complexation of the receptor with the fullerenes. The binding affinities of the tweezers with C60 and C70 were calculated to be 2.7(4)×104 and 8.01(7)×104 M−1, respectively by UV-vis and fluorescence spectroscopy.
  • Yoshiki Sasaki, Masayoshi Takase, Tetsuo Okujima, Shigeki Mori, Hidemitsu Uno
    Organic Letters 21 (6) 1900 - 1903 1523-7060 2019/03 [Peer-reviewed]
     Scientific journal 
    © 2019 American Chemical Society. Synthesis of an azacoronene, in which both pyrrole and azulene moieties are circularly fused, was achieved just in three steps. This new azacoronene exhibited multistep reversible oxidations under electrochemical and chemical conditions. Formation of an aromatic 22π-electron conjugation and a tropylium cation (6π-electron conjugation) in the dicationic state was revealed by the single-crystal X-ray crystallographic analysis as well as the nucleus-independent chemical shift (NICS) and anisotropy of the induced current density (ACID) calculations.
  • Tetsuo Okujima, Yusuke Hashimoto, Tomoya Furuta, Ritsuko Yamanaka, Guangnan Jin, Saika Otsubo, Shinji Aramaki, Shigeki Mori, Hiroko Yamada, Hidemitsu Uno, Noboru Ono
    Bulletin of the Chemical Society of Japan 92 (8) 1370 - 1378 0009-2673 2019 [Peer-reviewed]
     Scientific journal
  • Masahiro Narita, Takaaki Teraoka, Toshihiro Murafuji, Yoshihito Shiota, Kazunari Yoshizawa, Shigeki Mori, Hidemitsu Uno, Shinji Kanegawa, Osamu Sato, Kenta Goto, Fumito Tani
    Bulletin of the Chemical Society of Japan 92 (11) 1867 - 1873 0009-2673 2019 [Peer-reviewed]
     Scientific journal 
    © 2019 The Chemical Society of Japan. A helicene compound called AIBTh, wherein two azulene units are fused with isobenzothiophene, has been prepared and characterized by spectroscopic and crystallographic methods. The enantiomers of AIBTh were resolved by HPLC, exhibiting stable optical activity. AIBTh showed two reversible oxidation and one irreversible reduction waves with a HOMO-LUMO gap of 2.07 eV. Upon one-electron oxidation of AIBTh, its air-stable cation radical was isolated and analyzed by EPR as well as X-ray crystallography. Based on the EPR spectrum, the crystal structure, and DFT calculation, it is suggested that favorable resonance structures including aromatic tropylium cation forms and wide delocalization of electronic spin are dominating in the electronic structure of the cation radical.
  • Hidemitsu Uno, Mako Hirose, Takayuki Honda, Shigeki Mori, Masayoshi Takase, Tetsuo Okujima
    Bulletin of the Chemical Society of Japan 92 (5) 1001 - 1007 0009-2673 2019 [Peer-reviewed]
     Scientific journal 
    © 2019 The Chemical Society of Japan Di(acenaphtho)-fused BODIPYs with four electron-withdrawing N,N-dimethylcarbamoyl groups were obtained by complexation of the corresponding dipyrrins, which were also proven to be a stable deep-red dye.
  • Hidemitsu Uno, Misaki Ishiwata, Kota Muramatsu, Masayoshi Takase, Shigeki Mori, Tetsuo Okujima
    Bulletin of the Chemical Society of Japan 92 (5) 973 - 981 0009-2673 2019 [Peer-reviewed]
     Scientific journal 
    © 2019 The Chemical Society of Japan. 1,3-Dihydrothieno[3,4-a]- and 1,3,8,10-tetrahydrodithieno-[3,4-a;3¤4¤-m]-HPHACs were prepared by the successive SNAr reactions of hexafluorobenzene with 1,3-dihydrothieno[3,4-c]-pyrrole and 3,4-dihexylpyrrole followed by Scholl oxidation. Oxidation of 1,3-dihydrothieno-fused HPHACs with excess amounts of iodine at room temperature quantitatively gave the corresponding dication bis(triiodide)s. Further dehydrogenative oxidation of the dicationic species with iodine giving a thieno-[3,4-a]HPHAC dication was achieved at a higher temperature by removing hydrogen iodide generated during the reaction. Neutral species of thieno[3,4-a]HPHAC could not be isolated.
  • Tetsuo Okujima, Kota Muramatsu, Shigeki Mori, Masayoshi Takase, Hidemitsu Uno
    Heterocycles 99 (2) 1434 - 1443 0385-5414 2019 [Peer-reviewed]
     Scientific journal 
    © 2019 The Japan Institute of Heterocyclic Chemistry. We have successfully synthesized 2,3-di(3-thienyl)benzo[b]porphyrin based on retro Diels-Alder reaction of bicyclo[2.2.2]octadiene(BCOD)-fused porphyrin and investigated its photoisomerization reaction.
  • Tetsuo Okujima, Hayato Inaba, Shigeki Mori, Masayoshi Takase, Hidemitsu Uno
    Journal of Porphyrins and Phthalocyanines 1088-4246 2019 [Peer-reviewed]
     Scientific journal 
    © 2019 World Scientific Publishing Company. A ring-contracted carbaporphyrin, azulitriphyrin(2.1.1), was synthesized via intramolecular McMurry coupling reaction. Absorption, NMR spectra and NICS calculations of protonated azulitriphyrin(2.1.1) revealed its Hückel aromatic character as a 14 porphyrinoid.
  • Akio Kamimura, Ryusuke Watanabe, Tomoki Fukumitsu, Kazuki Ikeda, Takuji Kawamoto, Michinori Sumimoto, Shigeki Mori, Hidemitsu Uno
    Tetrahedron 74 (38) 5303 - 5308 0040-4020 2018/09 [Peer-reviewed]
     Scientific journal 
    © 2018 Elsevier Ltd New types of macrocyclic compounds, deltaarenes, are prepared. The compounds were readily synthesized in three steps from an arenedithiol and benzoquinone, and the yields of the macrocyclization reaction reached up to 40% under high dilution conditions. X-ray crystallographic analysis revealed that the macrocycle has a relatively rigid trimeric structure with a unique triangular hole, the size of which was approximately 11 Å along each side. NMR data suggests that the ring has a C3-symmetric structure. The X-ray analysis showed that the hole is large enough to capture one molecule of chlorobenzene. Use of a variety of dithiols allowed the synthesis of different types of deltaarene derivatives. MO calculations showed that the hole size depends on the dithiol unit. Deprotection of the twelve methoxyl groups was easily achieved by treatment with BBr3 and yielded the free-OH deltaarene derivative.
  • Kosuke Oki, Masayoshi Takase, Shigeki Mori, Akitoshi Shiotari, Yoshiaki Sugimoto, Keishi Ohara, Tetsuo Okujima, Hidemitsu Uno
    Journal of the American Chemical Society 140 (33) 10430 - 10434 0002-7863 2018/08 [Peer-reviewed]
     Scientific journal 
    Copyright © 2018 American Chemical Society. A core-expanded, pyrrole-fused azacoronene analogue containing two unusual N-doped heptagons was obtained from commercially available octafluoronaphthalene and 3,4-diethylpyrrole in two steps as a heteroatom-doped nonplanar nanographene. Full fusion with the formation of the tetraazadipleiadiene framework and the longitudinally twisted structure was unambiguously confirmed by single-crystal X-ray diffraction analysis. The edge-to-edge dihedral angle along the acene moiety was 63°. This electron-rich π-system showed four reversible oxidation peaks. Despite the nonplanar structure, the Hückel aromaticity owing to a peripheral π-conjugation in the dicationic state was concluded from the bond-length alternation and nucleus-independent chemical shift (NICS) and anisotropy of the induced current density (ACID) calculations.
  • Akitoshi Shiotari, Koichi Tanaka, Takahiro Nakae, Shigeki Mori, Tetsuo Okujima, Hidemitsu Uno, Hiroshi Sakaguchi, Yoshiaki Sugimoto
    Journal of Physical Chemistry C 122 (9) 4997 - 5003 1932-7447 2018/03 [Peer-reviewed]
     Scientific journal 
    © 2018 American Chemical Society. The adsorption configurations of heptahelicene ([7]H) molecules on Cu(001) are investigated with noncontact atomic force microscopy (ncAFM) and scanning tunneling microscopy (STM). Because of the suppression of thermal diffusion at 5 K, racemic [7]H molecules exist as monomers, dimers, trimers, and tetramers on the surface. The terminal naphthaleno part of the molecule is attached horizontally to the substrate so that the two benzene ring centers are located at the hollow sites, whereas the other terminal is protruded toward a vacuum. A procedure for picking a [7]H molecule up from the surface (vertical manipulation) enables us to functionalize the tip apex to enhance the spatial resolution of ncAFM. The ncAFM images with the helicene tip clarify that whereas the tetramers are homochiral, the dimers and trimers are heterochiral. In contrast, homochiral dimers and trimers are unobservable probably because of the rapid formation of the stable homochiral tetramers. Thus, ncAFM imaging can identify the geometries and chiralities of the individual component molecules in a nondestructive manner, which would be an indispensable method to characterize complicated chiral aggregates at the single-molecule level.
  • Hidemitsu Uno, Takayuki Honda, Manami Kitatsuka, Shogo Hiraoka, Shigeki Mori, Masayoshi Takase, Tetsuo Okujima, Takahiro Nakae
    RSC Advances 8 (25) 14072 - 14083 2018 [Peer-reviewed]
     Scientific journal 
    © 2018 The Royal Society of Chemistry. Benzene-fused bis(acenaphthoBODIPY)s prepared by retro-Diels-Alder reaction of bicyclo[2.2.2]octadiene-fused precursors showed strong absorption bands in the near-infrared region and very weak absorptions in the visible region.
  • Genki Watanabe, Hiroshi Sekiya, Eiji Tamai, Ryosuke Saijo, Hidemitsu Uno, Shigeki Mori, Toru Tanaka, Jun Maki, Masami Kawase
    Chemical and Pharmaceutical Bulletin 66 (7) 732 - 740 0009-2363 2018 [Peer-reviewed]
     Scientific journal 
    © 2018 The Pharmaceutical Society of Japan. Three 2-fluoroacetonylbenzoxazole ligands 1a–c and their new Zn(II) complexes 2a–c have been synthesized. In addition, syntheses of new metal [Mg(II), Ni(II), Cu(II), Pd(II), and Ag(I)] complexes from 1a have been also described. The molecular and crystal structures of six metal complexes 2b and 2d–h were determined by single-crystal X-ray diffraction analyses. Their antibacterial activities against six Gram-positive and six Gram-negative bacteria were evaluated by minimum inhibitory concentrations (MIC), which were compared with those of appropriate antibiotics and silver nitrate. The results indicate that some metal compounds have more antibacterial effects in comparison with free ligands and have preferred antibacterial activities that may have potential pharmaceutical applications. Noticeably, the Ag(I) complex 2h exhibited low MIC value of 0.7µM against Pseudomonas aeruginosa, which was even superior to the reference drug, Norfloxacin with that of 1.5µM. Against P. aeruginosa, 2h is bacteriostatic, exerts the cell surface damage observed by scanning electron microscopy (SEM) and is less likely to develop resistance. The new 2h has been found to display effective antimicrobial activity against a series of bacteria.
  • Tetsuo Okujima, Toshiki Abe, Shigeki Mori, Takahiro Nakae, Hidemitsu Uno
    Heterocycles 96 (7) 1239 - 1247 0385-5414 2018 [Peer-reviewed]
     Scientific journal 
    © 2018 The Japan Institute of Heterocyclic Chemistry. A series of sapphyrins fused with bicyclo[2.2.2]octadiene were successfully synthesized via [3+1+1] porphyrinoid synthesis. The retro Diels-Alder thermal conversion afforded the corresponding di-, tri-, tetra-, and pentabenzosapphyrins.
  • Hidemitsu Uno, Kazunari Tagawa, Shigeki Mori, Tetsuo Okujima, Masayoshi Takase, Takahiro Nakae
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 90 (12) 1375 - 1381 0009-2673 2017/12 Scientific journal 
    In this study, a benzene-fused bis(thiaporphyrin) was synthesized by the retro-Diels-Alder reaction of a bicyclo[2.2.2]octadiene (BCOD)-fused bis(thiaporphyrin) precursor. This precursor was prepared by the double [3+ 1] porphyrin synthesis of the BCOD-fused dipyrrole with thiatripyrrane. The ultraviolet-visible (UV-vis) spectrum of benzene-fused bis( thiaporphyrin) in dichloromethane was extremely different from that of the corresponding benzene-fused bis(porphyrin). In contrast, extremely similar spectra were obtained in the presence of trifluoroacetic acid. The similar electronic structures in the protonated states were supported by X-ray analysis and time-dependent density-functional theory (TD-DFT) calculations.
  • Shaotang Song, Guanbo Huang, Takahiro Kojima, Takahiro Nakae, Hidemitsu Uno, Hiroshi Sakaguchi
    CHEMISTRY LETTERS 46 (10) 1525 - 1527 0366-7022 2017/10 [Peer-reviewed]
     Scientific journal 
    We report covalently interchain-linked graphene nanoribbons fabricated on Au(111) by a stepwise growth process via two-zone chemical vapor deposition. Prepolymer arrays were grown by surface-assisted polymerization of a precursor, 1,9-dibromodibenzo[g,p]chrysene at 250 degrees C. Further annealing at 450 degrees C converted the prepolymers into interchain-linked graphene nanoribbons via intramolecular and intermolecular dehydrogenation reactions.
  • Akio Kamimura, Ryuichiro Yo, Hidemitsu Uno
    TETRAHEDRON 73 (32) 4770 - 4778 0040-4020 2017/08 [Peer-reviewed]
     Scientific journal 
    Chiral 2,3-trans-substituted piperidines were readily prepared in three steps from beta-amino-alpha-methylene esters, which were prepared by the Michael/Mannich domino reaction of chiral sulfinimines. Hydrogenation of the N-tosyl-2-aryl-1,2,5,6-tetrahydropyridine intermediates took place smoothly in the presence of a Pd/C catalyst to give trans-2,3-disubstituted piperidines in good yields and in a highly stereoselective manner. The total synthesis of optically active (25,3R)-(-)-epi-CP-99,994 was achieved in six-steps from an unsaturated piperidine. (C) 2017 Elsevier Ltd. All rights reserved.
  • Akitoshi Shiotari, Takahiro Nakae, Kota Iwata, Shigeki Mori, Tetsuo Okujima, Hidemitsu Uno, Hiroshi Sakaguchi, Yoshiaki Sugimoto
    Nature Communications 8 2041-1723 2017/07 [Peer-reviewed]
     Scientific journal 
    Controlling the structural deformation of organic molecules can drive unique reactions that cannot be induced only by thermal, optical or electrochemical procedures. However, in conventional organic synthesis, including mechanochemical procedures, it is difficult to control skeletal rearrangement in polycyclic aromatic hydrocarbons (PAHs). Here, we demonstrate a reaction scheme for the skeletal rearrangement of PAHs on a metal surface using high-resolution noncontact atomic force microscopy. By a combination of organic synthesis and on-surface cyclodehydrogenation, we produce a well-designed PAH - diazuleno[1,2,3-cd:1′,2′,3′-fg]pyrene - adsorbed flatly onto Cu(001), in which two azuleno moieties are highly strained by their mutual proximity. This local strain drives the rearrangement of one of the azuleno moieties into a fulvaleno moiety, which has never been reported so far. Our proposed thermally driven, strain-induced synthesis on surfaces will pave the way for the production of a new class of nanocarbon materials that conventional synthetic techniques cannot attain.
  • Kazunari Tagawa, Shigeki Mori, Tetsuo Okujima, Masayoshi Takase, Hidemitsu Uno
    TETRAHEDRON 73 (6) 794 - 801 0040-4020 2017/02 [Peer-reviewed]
     Scientific journal 
    The protonation behavior of bicyclo[2.2.2]octadiene (BCOD)-fused thiaporphyrin and thiabenzoporphyrin was examined by titration with trifluoroacetic acid. Neutral, monorotonated, and diprotonated species of thiaporphyrins were easily detected by UV-vis spectral measurement. The first (K-1) and second (K-2) equilibrium constants were found to be K-1 = 520 and K-2 approximate to 7.1 for BCOD-fused thiaporphyrin and K-1 = 1.4 x 10(4) and K-2 approximate to 1.4 for thiabenzoporphyrin. The difference between K-1 and K-2 values of thiaporphyrins is larger than that observed for porphyrins (N-4-porphyrins). The main contributing conjugation pathways for thiaporphyrins in both protonated species were investigated by NICS and AICD quantum calculations using their atomic geometries obtained by X-ray structural analysis. The 18 pi-conjugation pathways of the neutral, monoprotonated, and diprotonated species thiaporphyrins were found to contain 18, 19, and 20 atoms, respectively. Results of H-1 NMR studies also support the major contributing pathways. (C) 2016 Elsevier Ltd. All rights reserved.
  • Shogo Hiraoka, Hiroyuki Tahara, Shigeki Mori, Tetsuo Okujima, Masayoshi Takase, Takahiro Nakae, Hidemitsu Uno
    TETRAHEDRON 73 (7) 957 - 963 0040-4020 2017/02 [Peer-reviewed]
     Scientific journal 
    Parikh-Doering oxidation of diethyl 9-hydroxy-2,6-dimethy1-4,8-dihydro-4,8-methanopyrrol[3,4-f]isoindole-1,7-dicarboxylate produced diethyl 9-oxo-2,6-dimethy1-4,8-dihydro-4,8-methanopyrrol[3,44] isoindole-1,7-dicarboxylate. This carbonyl derivative spontaneously underwent cheletropic extrusion of carbon monoxide, producing diethyl 2,6-dimethylpyrrol[3,4-f]isoindole-1,7-dicarboxylate, which showed 14 pi-electronic aromaticity on the whole five-six-five ring system. (C) 2017 Elsevier Ltd. All rights reserved.
  • Kosuke Oki, Kazunari Tagawa, Shigeki Mori, Masayoshi Takase, Tetsuo Okujima, Hidemitsu Uno
    CHEMISTRY LETTERS 46 (2) 243 - 244 0366-7022 2017/02 [Peer-reviewed]
     Scientific journal 
    A cyclophane composed of diethanoanthracene (DEA)-fused dipyrrole and tetrafluorobenzene was synthesized by one-pot aromatic nucleophilic substitution (SNAr). Reflecting the fixed angle of DEA-fused dipyrrole, X-ray single-crystal structure analysis of the cyclophane revealed its rice-ball-shaped structure.
  • Masami Kawase, Ryosuke Saijo, Shigeki Mori, Hidemitsu Uno
    Heterocycles 94 (11) 2103 - 2110 0385-5414 2017 Scientific journal 
    © 2017 The Japan Institute of Heterocyclic Chemistry. 4-Trifluoroacetyl-3-phenylsydnone was first synthesized by trifluoromethylation of 4-formyl-3-phenylsydnone followed by oxidation of the corresponding trifluoromethyl alcohol. The structure of the product was determined by single-crystal X-ray analysis.
  • Akio Kamimura, Koichiro Miyazaki, Takuji Kawamoto, Hidemitsu Uno
    TETRAHEDRON 72 (48) 7722 - 7726 0040-4020 2016/12 [Peer-reviewed]
     Scientific journal 
    The radical cascade reaction of allyltin with aza-1,6-enyne compounds was studied. Optically active aza-1,6-enynes underwent a radical cascade process in the presence of a high concentration of allyltributyltin to give stannolanes as the major isomer. Piperidines were also observed in small amounts when an allylic unit was introduced stereoselectively to the trans-position of the aryl group at the C2 position. The yield of the products dramatically decreased with concentrations of tin reagent. The E/Z selectivity at the exomethylene group in piperidine depended on the reaction temperature, and it almost doubled when the reaction was carried out at 30 degrees C. In this study, the reaction mechanism of the radical cascade is discussed. (C) 2016 Elsevier Ltd. All rights reserved.
  • Ryosuke Saijo, Hidemitsu Uno, Masami Kawase
    HETEROCYCLES 92 (11) 2047 - 2058 0385-5414 2016/11 [Peer-reviewed]
     Scientific journal 
    A novel one-pot conversion of mesoionic 4-trifluoroacetyl-1,3-oxazolium-5-olates into imidazo[1,5-a]pyrazin-8(7.H)-ones by the reaction with TosMIC is described. The structure of the product was determined by single-crystal X-ray analysis.
  • Tetsuo Okujima, John Mack, Jun Nakamura, Gugu Kubheka, Tebello Nyokong, Hua Zhu, Naoki Komobuchi, Noboru Ono, Hiroko Yamada, Hidemitsu Uno, Nagao Kobayashi
    CHEMISTRY-A EUROPEAN JOURNAL 22 (41) 14730 - 14738 0947-6539 2016/10 [Peer-reviewed]
     Scientific journal 
    A series of porphyrins fused with acenaphthylene, phenanthroline, and benzofluoranthene polycyclic aromatic rings were prepared by means of a 3+1 porphyrin synthesis approach and subsequent retro-Diels-Alder reaction of bicyclo[2.2.2]octadiene-fused precursors. Analysis of the magnetic circular dichroism spectra and the results of time-dependent DFT calculations are used to identify the reasons for the trends observed in the wavelengths and relative intensities of the Q bands of the products. Michl's perimeter model is used as a conceptual framework to explain the changes in the relative energies of the frontier -molecular orbitals.
  • Chika Nozaki Kato, Wataru Unno, Sakie Kato, Tsukasa Ogasawara, Toshifumi Kashiwagi, Hidemitsu Uno, Kosuke Suzuki, Noritaka Mizuno
    CATALYSIS LETTERS 146 (10) 2119 - 2128 1011-372X 2016/10 [Peer-reviewed]
     Scientific journal 
    The organozirconium complex with alpha-Keggin-type mono-aluminum-substituted silicotungstate, [(n-C4H9)(4)N](6)[alpha-SiW11Al(OH)(2)O38ZrCp2](2)center dot 2H(2)O (TBA-Si-Al-Zr) was synthesized by the reaction of Cp2Zr(OTf)(2)center dot THF (or Cp2ZrCl2) with [(n-C4H9)(4)N](4)K0.5H0.5[alpha-SiW11{Al(OH2)}O-39]center dot H2O in acetonitrile. This compound showed high catalytic activities for Meerwein-Ponndorf-Verley reduction of ketones with 2-propanol in both homogeneous and heterogeneous system. [GRAPHICS] .
  • Masatoshi Ishida, Toshihiro Omagari, Ryuji Hirosawa, Keisuke Jono, Young Mo Sung, Yuhsuke Yasutake, Hidemitsu Uno, Motoki Toganoh, Hajime Nakanotani, Susumu Fukatsu, Dongho Kim, Hiroyuki Furuta
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55 (39) 12045 - 12049 1433-7851 2016/09 [Peer-reviewed]
     Scientific journal 
    Complexation of novel multiply N-confused expanded calix[n]phyrins with boron difluoride afforded a new class of cyclic BODIPY (boron-dipyrromethene) arrays. The structures of circularly arranged BODIPY subunits linked in an N-confused fashion give rise to such photophysical properties unique to the macrocycles as red-shifted emission wavelengths along with apparent large Stokes shifts, long emission lifetimes, and solid-state lasing. The DFT calculations support the size-dependent excited-state dynamics of the macrocycles.
  • Kazunari Tagawa, Shigeki Mori, Masayoshi Takase, Tetsuo Okujima, Ichiro Hisaki, Hidemitsu Uno
    TETRAHEDRON LETTERS 57 (36) 4079 - 4081 0040-4039 2016/09 [Peer-reviewed]
     Scientific journal 
    In this study, hexagonal shape-persistent cyclophane with D-2h symmetry and rigid dihedral angles was obtained through the key SNAr reaction of perfluorobenzene moieties and dipyrroles. The X-ray analysis of the compound thus obtained revealed a hexagonal macrocyclic structure with D-2h symmetry due to the dihedral angles of 120 degrees and double 120 degrees for bicyclo[2.2.2]octadiene:fused dipyrrole and syn-diethanotetrahydroanthracene-fused dipyrrole, respectively. (C) 2016 Elsevier Ltd. All rights reserved.
  • Takaaki Moriyama, Takuji Kawamoto, Hidemitsu Uno, Akio Kamimura
    HETEROCYCLES 92 (8) 1479 - 1489 0385-5414 2016/08 [Peer-reviewed]
     Scientific journal 
    Treatment of optically active 6-nitrohex-1-en-3-ols with Ag2O and iodine under basic conditions resulted in an oxidative intramolecular cyclization reaction to give isoxazoline-N-oxide along with bicyclo[3.1.0]hexane. The stereoselectivity and chemoselectivity of the reaction depended on the configuration of the stereogenic center adjacent to the alkenyl group. The structure was determined by X-ray crystallographic analyses as well as coupling constants from NMR data. Stereochemical preferences in the transition structure of the reaction are discussed.
  • Tetsuo Okujima, Hiroki Matsumoto, Shigeki Mori, Takahiro Nakae, Masayoshi Takase, Hidemitsu Uno
    TETRAHEDRON LETTERS 57 (29) 3160 - 3162 0040-4039 2016/07 [Peer-reviewed]
     Scientific journal 
    A complex of Cyclo[8]pyrrole with polyoxometalate, POM-to-Rings, was synthesized by anion exchange from cyclo[8]pyrrole sulfate. X-ray crystallographic study revealed the double-decker structure. (C) 2016 Elsevier Ltd. All rights reserved.
  • Akio Kamimura, Takaaki Moriyama, Yuji Ito, Takuji Kawamoto, Hidemitsu Uno
    JOURNAL OF ORGANIC CHEMISTRY 81 (11) 4664 - 4681 0022-3263 2016/06 [Peer-reviewed]
     Scientific journal 
    Optically active bicyclic nitrocyclopropanes are readily prepared from primary chiral nitro compounds, prepared by the conjugate addition of propionaldehyde to a nitro alkene in the presence of proline-derived organocatalysts. The one-step cyclopropanation took place smoothly in a highly stereoselective manner regardless of the stereogenic center adjacent to the allylic unit. Although the allylation reaction catalyzed by BF3 center dot OEt2, provides a mixture of two possible diastereomers, subsequent oxidation of the alcoholic carbon after the formation of nitrocyclopropanes gave diastereomerically pure single products. As a result, separation of the diastereomers during the reaction sequence is unnecessary. Baeyer-Villiger oxidation of the bicyclic nitrocyclopropane ketones followed by enolization resulted in stereoselective formation of a novel cyclopenta[b]furan ring in good yield via ring expansion followed by transannular nudeophilic cyclization.
  • Tetsuo Okujima, Chie Ando, Saurabh Agrawal, Hiroki Matsumoto, Shigeki Mori, Keishi Ohara, Ichiro Hisaki, Takahiro Nakae, Masayoshi Takase, Hidemitsu Uno, Nagao Kobayashi
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 138 (24) 7540 - 7543 0002-7863 2016/06 [Peer-reviewed]
     Scientific journal 
    An acenaphthylene-fused cyclo[10]pyrrole 1b was selectively synthesized via an oxidative coupling reaction of the corresponding 2,2'-bipyrrole with the appropriate dianion template, croconate anion. The structure of 1b as the isolated largest cyclo[n]pyrrole was elucidated by X-ray crystallographic analysis. The absorption spectrum exhibited a markedly red-shifted, intensified L band at 1982 nm, which was interpreted by application of Michl's perimeter and Gouterman's 4-orbital models, supported by magnetic circular dichroism (MCD) data and theoretical calculations.
  • Ryosuke Saijo, Hidemitsu Uno, Shigeki Mori, Masami Kawase
    CHEMICAL COMMUNICATIONS 52 (51) 8006 - 8009 1359-7345 2016 [Peer-reviewed]
     Scientific journal 
    Trialkyl phosphites were evaluated as phosphorus nucleophiles for addition to mesoionic 4-trifluoroacetyl-1,3-oxazolium-5-olates (1), thereby producing tetravalent phosphorus zwitterions (2) in good yields. The structure of 2 was determined to be a tetravalent phosphonium enolate via single crystal X-ray analysis.
  • Akio Kamimura, Mari Ishikawa, Ryusuke Watanabe, Sanshiro Sakamoto, Hidemitsu Uno
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS 190 (8) 1219 - 1224 1042-6507 2015/08 Scientific journal 
    Unsymmetrically substituted 8-methoxy-2-hydroxy-3,7-diarylthiodibenzofurans were readily prepared by the intramolecular oxidative condensation reaction of hydroquinone dimers in good yields.
  • Syntheses and X-Ray Crystal Structures of Magnesium-Substituted Polyoxometalates
    Chika Nozaki Kato, Nami Ukai, Daisuke Miyamae, Shunya Arata, Toshifumi Kashiwagi, Masaru Nagami, Toshiya Mori, Yusuke Kataoka, Yasutaka Kitagawa, Hidemitsu Uno
    Advanced Topics in Crystallization 2015/06 [Peer-reviewed]
     Scientific journal
  • Toshiki Nokami, Yu Yamane, Shunsuke Oshitani, Jun-ka Kobayashi, Shin-ichiro Matsui, Takashi Nishihara, Hidemitsu Uno, Shuichi Hayase, Toshiyuki Itoh
    ORGANIC LETTERS 17 (12) 3182 - 3185 1523-7060 2015/06 [Peer-reviewed]
     Scientific journal 
    Iron salt-catalyzed Friedel-Crafts alkylation of chiral alpha-aryl alcohols with a trimethylsilyl group was found to proceed with retention of the configuration of the hydroxyl group as a leaving group. The memory of chirality of this system stems from the beta-silyl effect of the trimethylsilyl group on the carbocation intermediate.
  • Akio Kamimura, Tatsuro Yoshinaga, Fumiaki Noguchi, Koichiro Miyazaki, Hidemitsu Uno
    Organic Chemistry Frontiers 2 (6) 713 - 720 2052-4129 2015 [Peer-reviewed]
     Scientific journal 
    A kinetic study on radical cascade reactions of 1,6-enyne compounds was undertaken. The efficiency of the reaction depended on the presence of an ester group at the alkene unit, which clearly suggests that the addition of a tin radical was accelerated by the alpha,beta-unsaturated system. Stannolane formation progressed very quickly after a short induction period and completed within 12 min in the presence of Bu3SnH at 10(-2) M concentration at 110 degrees C. Product ratios between stannolane and exo-methylene compound depended on the concentration of Bu3SnH; a linear relationship was observed between the ratios of the two and the concentration of Bu3SnH. These results clearly indicate that the S(H)i process is irreversible. The slope of the graph allowed us to estimate the k(s) value, the S(H)i reaction rate at the tin atom, as 4.23 x 10(8) s(-1) at 303 K. The use of Bu2PhSnH for the reaction suggests that the S(H)i process partially progresses by the frontside attack of the vinyl radical, which generates a methylene radical that undergoes neophyl rearrangement to give methylene piperidine in a cis-selective manner.
  • Hidemitsu Uno, Mitsunori Nakamura, Kazuki Jodai, Shigeki Mori, Tetsuo Okujima
    HETEROCYCLES 90 (2) 1158 - 1167 0385-5414 2015/01 Scientific journal 
    4,8-Dihydropyrrol[3,4-f]isoindole was prepared from 4,7-dihydroisoindole based on the modified Barton-Zard reaction. Addition of phenylsulfenyl chloride followed by oxidation and dehydrochlorination gave phenylsulfonyldihydroisoindole, which underwent the smooth reaction with an isocyanoacetate under basic conditions to give 4,8-dihydropyrrol[3,4-f]isoindole-1,5- and 1,7-dicarboxylates in good yields. The pyrrolisoindole was successfully converted to the benzene-fused bisBODIPY, absorption maximum of which was 758 nm.
  • Hidemitsu Uno, Masaki Yoshino, Aya Seike, Shigeki Mori, Takahiro Nakae, Tetsuo Okujima
    HETEROATOM CHEMISTRY 25 (5) 367 - 378 1042-7163 2014/11 Scientific journal 
    Electrophilic phenylsulfenylation of syn-7-tert-butoxy-2-phenylsulfonyl- bicyclo[2.2.1] hepta-2,5-diene with phenylsulfenyl chloride yielded a mixture of three simple adducts, two of which were derived by the endo face attack of the phenylsulfenyl cation. In the analogous reaction with the anti derivative, only one adduct with the exo phenylsulfanyl group at the nearer carbon was obtained. This product was derived by the attack of the phenylsulfenyl cation from the exo face followed by the endo attack of a chloride anion at the carbon opposite to the phenylsulfonyl group. The similar reaction of 7-tert-butoxybicyclo[2.2.1]hepta-2,5-diene itself underwent no Wager-Meerwein-type rearrangement or transannular reaction, and simple adducts were formed in good combined yield. The combined yield of the products reacted at the syn double bond was ca. 80%.
  • Masatoshi Ishida, Kensuke Nakahara, Ryuichi Sakashita, Tomoya Ishizuka, Motonori Watanabe, Hidemitsu Uno, Atsuhiro Osuka, Hiroyuki Furuta
    JOURNAL OF PORPHYRINS AND PHTHALOCYANINES 18 (10-11) 909 - 918 1088-4246 2014/10 [Peer-reviewed]
     Scientific journal 
    Synthesis of bona fide N-confused phlorin derivatives through simple chemical reduction of N-confused porphyrin precursors using sodium borohydride, p-toluenesulfonyl hydrazide, etc. is described. Spectroscopic, X-ray diffraction analyses and DFT-assisted calculations of these species support the nonaromatic phlorin electronic structure.
  • Tetsuo Okujima, Yoichi Shida, Keishi Ohara, Yuya Tomimori, Motoyoshi Nishioka, Shigeki Mori, Takahiro Nakae, Hidemitsu Uno
    JOURNAL OF PORPHYRINS AND PHTHALOCYANINES 18 (8-9) 752 - 761 1088-4246 2014/08 Scientific journal 
    A series of O-chelated BODIPYs fused with aromatic rings such as benzene and acenaphthylene at beta,beta-positions was synthesized as a near-infrared dye. The photophysical properties were examined by UV-vis-NIR absorption and fluorescence measurement. Acenaphthylene-fused O-BODIPYs showed a intense absorption at 750-840 nm with the epsilon of 10(5) M-1.cm(-1). and a fluorescene emission at 770-850 nm with the high Phi value of 0.06-0.43.
  • Akio Kamimura, Yu Yamane, Ryuichiro Yo, Toshiyuki Tanaka, Hidemitsu Uno
    JOURNAL OF ORGANIC CHEMISTRY 79 (16) 7696 - 7702 0022-3263 2014/08 [Peer-reviewed]
     Scientific journal 
    Optically active seven-membered lactones, dimethyleneoxazepanones, were readily prepared in good yields from chiral beta-(N-propargylic)-amino-alpha-methylene carboxylic add tert-butyl esters in the presence of catalytic amounts of Ph3PAuCl and Cu(OTf)(2) A smooth 7-exo-dig cyclization was observed.
  • Chika Nozaki Kato, Toshifumi Kashiwagi, Wataru Unno, Miyuki Nakagawa, Hidemitsu Uno
    INORGANIC CHEMISTRY 53 (10) 4824 - 4832 0020-1669 2014/05 [Peer-reviewed]
     Scientific journal 
    The syntheses and molecular structures of the two types of alpha-Dawson-type trialuminum-substituted polyoxometalates, [B-alpha-H3P2W15O59{Al(OH2)}(3)](6-) (1) and [B-alpha-H3P2W15O59{Al(OH)}(2){Al(OH2)}](2)(16-) (2), are described herein. The potassium and cesium salts of 1, K-6[B-alpha-H3P2W15O59{Al(OH2)}(3)]center dot 14H(2)O (K-1), and Cs-6[B-alpha-H3P2W15O59{Al(OH2)}(3)]center dot 13H(2)O (Cs-1) were formed by a stoichiometric reaction in water of trilacunary alpha-Dawson polyoxotungstate with aluminum nitrate under acidic conditions (pH similar to 3). The potassium/sodium and tetramethylammonium/sodium salts of 2, K14Na2[B-alpha-H3P2W15O59{Al(OH)}(2) {Al (OH2)}](2) center dot 30H(2)O (KNa-2) and [(CH3)(4)N](14)Na-2[B-alpha-H3P2W15O59{Al(OH)}(2){Al(OH2)}](2) center dot 39H(2)O (TMANa-2) were obtained under basic conditions (pH similar to 9). These compounds were characterized by X-ray structure analyses elemental analyses, thermogravimetric/differential thermal analyses, Fourier transform infrared, and solution P-31, Al-27, and W-183 NMR spectroscopy. The polyoxoanion 1 is a monomeric, alpha-Dawson-type structure, resulting in an overall C-3v symmetry, while the polyoxoanion 2 is a hydrogen-bonded dimeric structure, resulting in an overall S-3 symmetry in the solid state. The pH dependence of polyoxoanions 1 and 2 in aqueous solution was also investigated by P-31 NMR spectroscopy.
  • Takahiro Nakae, Takashi Kikuchi, Shigeki Mori, Tetsuo Okujima, Toshihiro Murafuji, Hidemitsu Uno
    CHEMISTRY LETTERS 43 (4) 504 - 506 0366-7022 2014/04 Scientific journal 
    1,3-Bisarylated-2,2'-biazulene 1 and 1,1'-bisarylated-2,2'-biazulene 1' were obtained by the Suzuki-Miyaura crosscoupling reaction of 1,1',3,3'-tetrahalo-2,2'-biazulene 2 with 4-tert-butylphenylboronic acid (3b). The other two halogen atoms were reductively removed by hydrogenation under the same reaction conditions. The major regioisomer 1 was obtained with a selectivity of up to 94% (15:1) and a combined yield of 1 and 1' of up to 77%.
  • Ken-ichi Sakaguchi, Takuya Kamimura, Hidemitsu Uno, Shigeki Mori, Shuwa Ozako, Hirofumi Nobukuni, Masatoshi Ishida, Fumito Tani
    JOURNAL OF ORGANIC CHEMISTRY 79 (7) 2980 - 2992 0022-3263 2014/04 [Peer-reviewed]
     Scientific journal 
    Free-bases and a nickel(11) complex of phenothiazine-bridged cyclic porphyrin dimers bearing self-ssembling 4-pyridyl groups (M(2)PtzCPD(Py)(OCn); M = H-2 or Ni, OCn = OC6 or OC3) at opposite mesopositions have been prepared as host molecules for fullerenes. The freebase dimer (H(4)Ptz-CPDPy(OC6)) includes fullerenes with remarkably high association constants such as 3.9 +/- 0.7 x 10(6) M-1 for C-60 and 7.4 +/- 0.8 x 10(7) M-1 for C-70 in toluene. This C-60 affinity is the highest value ever among reported receptors composed of freebase porphyrins. The nickel dimer (Ni-2-Ptz-CPDPy(OC6)) also shows high affinities for C-60 (1.3 +/- 0.2 x 10(6) M-1) and C-70 (over 10(7) M-1). In the crystal structure of the inclusion complex of C-60 within H(4)PtzCPD(Py)(OC3()), the C-60 molecule is located just above the centers of the porphyrins. The two porphyrin planes are almost parallel to each other and the center-to-center distance (12.454 angstrom) is close to the optimal separation (similar to 12.5 angstrom) for C-60 inclusion. The cyclic porphyrin dimer forms a nanotube through its self-assembly induced by C-H center dot center dot center dot N hydrogen bonds between porphyrin beta-CH groups and pyridyl nitrogens as well as pi-pi interactions of the pyridyl groups. The C-60 molecules are linearly arranged in the inner channel of this nanotube.
  • Akio Kamimura, Tomomi Nokubi, Ryusuke Watanabe, Mari Ishikawa, Kotaro Nasu, Hidemitsu Uno, Michinori Sumimoto
    JOURNAL OF ORGANIC CHEMISTRY 79 (3) 1068 - 1083 0022-3263 2014/02 [Peer-reviewed]
     Scientific journal 
    4,4'-Disulfanyl-2,2',5,5'-tetrahydrobiaryl (5,5'-disulfanyl hydroquinone dimer) derivatives were readily synthesized from benzoquinone and thiols via an oxidative coupling reaction. The hydroquinone dimers showed strong fluorescence upon excitation at 330 nm, and it was observed that the presence of the sulfanyl groups at the C4 and C4' positions is important for achieving strong photoluminescence. The tetrapotassium salts of the hydroquinone dimers also showed good water solubility, but the fluorescence disappeared rapidly on dissolution in water. 2,2'- and 5,5'-protected biaryls were synthesized. The dipotassium salt of the 5,5'-dimethoxy-2,2'-dihydroxy derivative was observed to show good and stable fluorescence in water, while the dipotassium salt of the 2,2'-dirnethoxy-5,5'-dihydroxy derivative showed less water solubility. Introduction of propargyl groups was demonstrated to provide a convenient method for installing amino acids derivatives. This derivatization afforded potentially useful compounds for attaching the biologically active fragment to the fluorescent unit.
  • Tetsuo Okujima, Yoichi Shida, Keishi Ohara, Yuya Tomimori, Motoyoshi Nishioka, Shigeki Mori, Takahiro Nakae, Hidemitsu Uno
    J. Porphyrins Phthalocyanines 18 (8-9) 752 - 761 1099-1409 2014 [Peer-reviewed]
     Scientific journal 
    A series of O-chelated BODIPYs fused with aromatic rings such as benzene and acenaphthylene at β,β-positions was synthesized as a near-infrared dye. The photophysical properties were examined by UV-vis-NIR absorption and fluorescence measurement. Acenaphthylene-fused O-BODIPYs showed a intense absorption at 750–840 nm with the ε of 105 M-1.cm-1. and a fluorescence emission at 770–850 nm with the high Φ value of 0.06–0.43.


    Read More: http://www.worldscientific.com/doi/abs/10.1142/S1088424614500503
  • Kazunari Tagawa, Shigeki Mori, Takahiro Nakae, Tetsuo Okujima, Hidemitsu Une
    HETEROCYCLES 88 (1) 453 - 462 0385-5414 2014/01 Scientific journal 
    The Hinsberg thiophene synthesis using 4,5,6,7-tetrahydro-4,7-ethanothiophene-5,6-dione and diethyl thiodiglycolate afforded a mixture of diethyl 4,8-dihydro-4,8-ethanobenzo[1,2-c;4,5-c']dithiophene-1,3-dicarboxylate and its dihydrate, although the yields were low. The latter dihydrate was converted to the former dithiophene in a good yield by the treatment with Ac2O and DMAP.
  • Tetsuo Okujima, Chie Ando, Shigeki Mori, Takahiro Nakae, Hiroko Yamada, Hidemitsu Uno
    HETEROCYCLES 88 (1) 417 - 424 0385-5414 2014/01 [Peer-reviewed]
     Scientific journal 
    Cyclo[8]pyrrole with eight 9,10-dihydroanthracene wings was synthesized by oxidative coupling of the corresponding 2,2'-bipyrrole in good yield. The molecular structure was determined by single crystal X-ray analysis. The three-dimensionally structured cyclo[8]pyrrole possessed a cavity created by a pair of slip-stacked cyclo[8]pyrroles.
  • Mitsunori Nakamura, Manami Kitatsuka, Kohtaro Takahashi, Toshi Nagata, Shigeki Mori, Daiki Kuzuhara, Tetsuo Okujima, Hiroko Yamada, Takahiro Nakae, Hidemitsu Uno
    ORGANIC & BIOMOLECULAR CHEMISTRY 12 (8) 1309 - 1317 1477-0520 2014 [Peer-reviewed]
     Scientific journal 
    Bicyclo[2.2.2]octadiene-fused (BCOD-fused) bis(benzoborondipyrromethene)s (bisbenzoBODIPYs) bearing electron-withdrawing groups such as fluorine and cyano groups were prepared either by incorporating tetrafluoroisoindole moieties into BODIPY chromophores or by introducing cyano or ethoxycarbonyl groups at the 3,5-positions. The BCOD-fused bisbenzoBODIPYs were quantitatively converted to the corresponding benzene-fused bisbenzoBODIPYs by a retro-Diels-Alder reaction. The pi-fused bisbenzoBODIPYs were found to have intense absorption in the near-infrared region and not to have any strong absorption bands in the visible region. Moreover, the bisbenzoBODIPYs were stable under atmospheric conditions.
  • Daiki Kuzuhara, Zhaoli Xue, Shigeki Mori, Tetsuo Okujima, Hidemitsu Uno, Naoki Aratani, Hiroko Yamada
    Chemical Communications 49 (79) 8955 - 8957 1359-7345 2013/10 [Peer-reviewed]
     Scientific journal 
    Boron complexes of [14]triphyrins(2.1.1) were prepared from free-base [14]triphyrins(2.1.1) with phenylboron dichloride. The absorption spectrum of the meso-free β-alkyl-triphyrin boron complex in CH2Cl 2 showed a broad weak band at around 640 nm assigned to transition from B-phenyl to the triphyrin, while that of the meso-aryl benzotriphyrin boron complex showed only Soret and Q bands. © 2013 The Royal Society of Chemistry.
  • Tetsuo Okujima, Chie Ando, John Mack, Shigeki Mori, Ichiro Hisaki, Takahiro Nakae, Hiroko Yamada, Keishi Ohara, Nagao Kobayashi, Hidemitsu Uno
    CHEMISTRY-A EUROPEAN JOURNAL 19 (41) 13970 - 13978 0947-6539 2013/10 [Peer-reviewed]
     Scientific journal 
    An acenaphthylene-fused cyclo[8]pyrrole was synthesized by using an oxidative coupling reaction of the corresponding 2,2-bipyrrole. Two conformational isomers 1a and 1b were isolated, and their molecular structures were elucidated by X-ray crystallographic studies. The less-polar and lower-symmetry 1b isomer can be converted into the 1a isomer through a thermal ring flip. Application of the perimeter model developed by Michl to magnetic circular dichroism spectroscopic data and theoretical calculations demonstrate that there is a marked redshift of the near-IR absorption maxima relative to cyclo[8]isoindole because there is a significant stabilization of the LUMO due to the differing effects of a fused ring expansion with acenaphthylene and benzene moieties on the frontier molecular orbitals.
  • Kazuki Tanaka, Naoki Aratani, Daiki Kuzuhara, Sadaaki Sakamoto, Tetsuo Okujima, Noboru Ono, Hidemitsu Uno, Hiroko Yamada
    RSC Advances 3 (35) 15310 - 15315 2046-2069 2013/09 Scientific journal 
    We have synthesized 13,13′-(3,5-bis(trifluoromethyl)phenyl)-6, 6′-bipentacene from a soluble bispentacenequinone precursor. Bispentacene takes orthogonal conformation in the solid state and exhibits four reversible redox potentials. In addition, a tetracyanobipentacenequinodimethane was obtained for the first time from the pure bispentacenequinone. © The Royal Society of Chemistry 2013.
  • Ryosuke Saijo, Ken-ichi Kurihara, Kazuki Akira, Hidemitsu Uno, Masami Kawase
    TETRAHEDRON LETTERS 54 (33) 4418 - 4421 0040-4039 2013/08 Scientific journal 
    Treatment of mesoionic 1,3-oxazolium-5-olates with TosMIC in the presence of a base causes a novel ring transformation affording 2(1H)-pyrazinones in moderate yields. The origin of C-2 carbonyl oxygen in the product was elucidated to be molecular oxygen, based on O-18-labeling experiments. [GRAPHICS] . (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved.
  • Noriyuki Hatae, Jun Nakamura, Tetsuo Okujima, Minoru Ishikura, Takumi Abe, Satoshi Hibino, Tominari Choshi, Chiaki Okada, Hiroko Yamada, Hidemitsu Uno, Eiko Toyota
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 23 (16) 4637 - 4640 0960-894X 2013/08 [Peer-reviewed]
     Scientific journal 
    9,10-Phenanthrenequinone (9,10-PQ) is one of the most abundant quinones among diesel exhaust particulates. Recent data have suggested that quinones induce apoptosis in immune, epithelial and tumor cells, leading to respirator illness; however, the mechanisms by which quinones induce apoptosis and the structure required for this remain unknown. We studied the antitumor activity of 9,10-PQ analogs against two human tumor cell lines, HCT-116 colon tumor cells and HL-60 promyelocytic leukemia cells. The loss of the cis-orthoquinone unit in 9,10-PQ abrogated its ability to induce apoptosis in the two tumor cell lines, and the LC50 values of these analogs were indicated over 10 mu M. An analog of 9,10-PQ in which the biaryl unit had been deleted displayed a reduced ability to induce tumor cell apoptosis, while the analogs 1,10-phenanthroline-5,6-dione (9) and pyrene-4,5-dione (10), which also had modified biaryl units, exhibited increased tumor cell apoptotic activity. The cis-orthoquinone unit in 9,10-PQ was identified as essential for its ability to induce apoptosis in tumor cells, and its biaryl unit is also considered to influence orthoquinone-mediated apoptotic activity. (C) 2013 Elsevier Ltd. All rights reserved.
  • Akio Kamimura, Koichiro Miyazaki, Yu Yamane, Ryuichiro Yo, Shingo Ishikawa, Hidemitsu Uno, Michinori Sumimoto
    JOURNAL OF ORGANIC CHEMISTRY 78 (16) 7816 - 7822 0022-3263 2013/08 [Peer-reviewed]
     Scientific journal 
    Bicyclic dihydrothiophenes are readily prepared by a radical cascade cyclization reaction triggered by the addition of a thiyl radical under thermal or photoirradiation conditions. The translocated radical attacks the sulfur atom in the initial radical donor unit in an S(H)i manner. Sufficient stereoselectivity is achieved when a large excess of disulfide is used for the reaction under photoirradiation conditions. The reaction in the absence of solvents provides vinylsulfides instead of dihydrothiophenes. Thus, the sulfur atom in the thiyl radical serves as a sulfur biradical synthetic equivalent.
  • Koichiro Miyazaki, Yu Yamane, Ryuichiro Yo, Hidemitsu Uno, Akio Kamimura
    Beilstein Journal of Organic Chemistry 9 1326 - 1332 1860-5397 2013/07 [Peer-reviewed]
     Scientific journal 
    Bicyclodihydrosiloles were readily prepared from optically active enyne compounds by a radical cascade reaction triggered by tris(trimethylsilyl)silane ((Me3Si)3SiH). The reaction was initiated by the addition of a silyl radical to an α,β-unsaturated ester, forming an α-carbonyl radical that underwent radical cyclization to a terminal alkyne unit. The resulting vinyl radical attacked the silicon atom in an SHi manner to give dihydrosilole. The reaction preferentially formed trans isomers of bicyclosiloles with an approximately 7:3 to 9:1 selectivity. © 2013 Miyazaki et al.
  • Zhaoli Xue, Daiki Kuzuhara, Shinya Ikeda, Yuka Sakakibara, Kei Ohkubo, Naoki Aratani, Tetsuo Okujima, Hidemitsu Uno, Shunichi Fukuzumi, Hiroko Yamada
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 52 (28) 7306 - 7309 1433-7851 2013/07 [Peer-reviewed]
     Scientific journal
  • Tatsuya Aotake, Hiroshi Tanimoto, Hidekatsu Hotta, Daiki Kuzuhara, Tetsuo Okujima, Hidemitsu Uno, Hiroko Yamada
    Chemical Communications 49 (35) 3661 - 3663 1364-548X 2013/05 [Peer-reviewed]
     Scientific journal 
    The non-luminous precursor, 2-(1-pyrenyl)-9,10-dihydro-9,10- ethanoanthracene-11,12-dione, was photochemically converted to highly-fluorescent 2-(1-pyrenyl)anthracene quantitatively in solution and in the PMMA film and the fluorescence quantum yield of the acene in benzonitrile was as high as 0.99. © The Royal Society of Chemistry 2013.
  • Tatsuya Aotake, Yuko Yamashita, Tetsuo Okujima, Nobuhiko Shirasawa, Yukari Jo, Shigeo Fujimori, Hidemitsu Uno, Noboru Ono, Hiroko Yamada
    Tetrahedron Letters 54 (14) 1790 - 1793 0040-4039 2013/04 Scientific journal 
    Highly fluorescent naphthacene derivatives and their photoconvertible precursors were synthesized for irreversibly photo-responsive fluorescent molecules. The fluorescence quantum yields (Φf) of the precursors were less than 0.02, and the precursors can be converted to the highly fluorescent naphthacene derivatives (Φf = 0.67-0.70) quantitatively by photo-irradiation. © 2013 Elsevier Ltd. All rights reserved.
  • Akio Kamimura, Yu Yamane, Hidemitsu Uno
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS 188 (4) 356 - 366 1042-6507 2013/04 Scientific journal 
    Optically active 4-aminopyrolidines were prepared by radical cyclization induced by addition of tin radical to N-(2-(methoxyimino)ethyl)--amino--methylene esters, which were readily prepared by Michael/aldol domino reaction to chiral sulfinimines.
  • Akio Kamimura, Kosuke Ikeda, Takaaki Moriyama, Hidemitsu Uno
    TETRAHEDRON LETTERS 54 (14) 1842 - 1844 0040-4039 2013/04 Scientific journal 
    Reductive treatment of bicyclic nitrocyclopropanes with zinc powder under acidic conditions resulted in the double cleavage of carbon-carbon bonds in the cyclopropane to give vinyl nitrile in good yields. The reductive cleavage of carbon-carbon bond depended on the reaction conditions and sufficient acidic treatment gave alkenyl nitriles in good yields, while weak acidic treatment afforded oxime derivative instead. (C) 2013 Elsevier Ltd. All rights reserved.
  • Shin-ichi Nagaoka, Hidemitsu Uno, Dan Huppert
    JOURNAL OF PHYSICAL CHEMISTRY B 117 (16) 4347 - 4353 1520-6106 2013/04 [Peer-reviewed]
     Scientific journal 
    Time-resolved emission of aloesaponarin I was studied with the fluorescence up-conversion and time-correlated single-photon-counting techniques. The rates of the excited-state intramolecular proton transfer, of the solvent and molecular rearrangements, and of the decay from the excited proton-transferred species were determined and interpreted in the light of time-dependent density functional calculations. These results were discussed in conjunction with UV protection and singlet-oxygen quenching activity of aloe.
  • Akio Kamimura, Masahiro So, Shingo Ishikawa, Hidemitsu Uno
    Organic Letters 15 (6) 1402 - 1405 1523-7060 2013/03 [Peer-reviewed]
     Scientific journal 
    A novel double Migita-Kosugi-Stille coupling reaction with dihydrostannolanes, which are readily available from a radical cascade reaction, was achieved with dihalobenzenes in the presence of a palladium catalyst. Use of unsymmetrical 1-bromo-2-iodobenzene derivatives accomplished the double coupling reaction which gave tetrahydrobenz[f]isoindoles in a regioselective manner. © 2013 American Chemical Society.
  • Zhaoli Xue, Daiki Kuzuhara, Shinya Ikeda, Tetsuo Okujima, Shigeki Mori, Hidemitsu Uno, Hiroko Yamada
    INORGANIC CHEMISTRY 52 (4) 1688 - 1690 0020-1669 2013/02 [Peer-reviewed]
     Scientific journal 
    Metalation of 6,13,20,21-tetrakis(4-methyl-phenyl)-22H-tribenzo[14]triphyrin(2.1.1) with PtCl2 gave a platinum(II) complex having a square-planar coordination structure with two pyrrolic nitrogen atoms and two chloride ions, with a saddle-shaped macrocycle. This platinum(II) complex was easily oxidized by air to an octahedral platinum(IV) complex coordinated by three pyrrolic nitrogen atoms as a tridentate monoanionic cyclic ligand and three chloride ions. When platinum(II) triphyrin was crystallized in air, an oxygen atom was incorporated between two alpha-carbon atoms of the pyrroles as an oxygen bridge to intercept the 14 pi aromatic system.
  • Aya Seike, Kaoru Yamagami, Yoshimasa Kakitani, Miki Kuwajima, Hiroki Uoyama, Shin-ichi Nagaoka, Takahiro Nakae, Shigeki Mori, Tetsuo Okujima, Hidemitsu Uno
    RSC ADVANCES 3 (9) 3006 - 3016 2046-2069 2013 Scientific journal 
    Ethyl 12-oxo-4,11-dihydro-4,11-ethanonaphth[2,3-f]isoindole-1-carboxylate (2) was prepared from 7-tert-butoxynorbornadiene and quantitatively converted to ethyl naphth[2,3-f]isoindole-1-carboxylate (3) by the thermal or photochemical cheletropic reaction. Ethyl naphth[2,3-f] isoindole-1-carboxylate (3) existed in a 2H-form both in solution and as a solid, and gradually dimerized to give a dianthradiazafulvalene derivative under aerobic conditions.
  • John Mack, Jun Nakamura, Tetsuo Okujima, Hiroko Yamada, Hidemitsu Uno, Nagao Kobayashi
    Journal of Porphyrins and Phthalocyanines 17 (10) 996 - 1007 1099-1409 2013 Scientific journal 
    Magnetic circular dichroism (MCD) spectroscopy and TD-DFT calculations are used to analyze the electronic structure and optical properties of low-symmetry acenaphthoporphyrins with AAAB, ABAB and AABB structures. Evidence for dual fluorescence caused by tautomerism has been identified in the emission spectra of the AAAB and ABAB compounds. The sign sequences observed for the Q and B bands in the MCD spectra have been used to validate the results of the TD-DFT calculations. An anomalous +/- sign sequence is observed in the B band region with ascending energy similar to that reported previously for metal tetraphenyltetraacenaphthoporphyrin complexes. Copyright © 2013 World Scientific Publishing Company.
  • Chika Nozaki Kato, Yuki Makino, Wataru Unno, Hidemitsu Uno
    DALTON TRANSACTIONS 42 (4) 1129 - 1135 1477-9226 2013 [Peer-reviewed]
     Scientific journal 
    The synthesis and crystal structure of a zirconocene derivative with alpha-Keggin mono-aluminum-substituted polyoxotungstate, [alpha-PW11Al(OH)O39ZrCp2](2)(6-) (Cp = C5H5-) (1), which was obtained by the reaction of alpha-Keggin mono-aluminum-substituted polyoxotungstate with a biscyclopentadienylzirconium(IV) complex, is described herein. Analytically pure, homogeneous, yellow crystals of the tetra-n-butylammonium salt of polyoxoanion 1, [(n-C4H9)(4)N](6)[alpha-PW11Al(OH)O39ZrCp2](2) (TBA-1), were obtained from the ca. 1 : 1 reaction of [(n-C4H9)(4)N](4)[alpha-PW11{Al(OH2)}O-39] with Cp2Zr(OTf)(2)center dot THF (OTf = O3SCF3-) in acetonitrile solution under an argon atmosphere, followed by precipitation from water and crystallization from acetonitrile. TBA-1 was characterized based on X-ray structure analysis, elemental analysis, thermogravimetric/differential thermal analysis (TG/DTA), Fourier transform infrared (FTIR), and solution (P-31, Al-27, F-19, H-1, and C-13) nuclear magnetic resonance (NMR) spectroscopy. Single-crystal X-ray structure analysis revealed that the two {PW11AlO40} units are bridged by two "bent sandwich" Cp2Zr2+ fragments with C-2 symmetry. Each zirconium center was bound to a terminal oxygen atom of the aluminum and tungsten sites and an edge-sharing oxygen atom at the Al-O-W linkage. Further, the stability towards water was investigated by NMR (P-31, H-1, and C-13) and FTIR spectroscopy. The eta(5)-cyclopentadienylzirconium fragments were not eliminated from the surface of [alpha-PW11{Al(OH2)}O-39](4-) even after 24 h exposure to 50 equiv. of water.
  • Daiki Kuzuhara, Yuka Sakakibara, Shigeki Mori, Tetsuo Okujima, Hidemitsu Uno, Hiroko Yamada
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 52 (12) 3360 - 3363 1433-7851 2013 [Peer-reviewed]
     Scientific journal
  • Pyosang Kim, Sujin Ham, Juwon Oh, Hiroki Uoyama, Hajime Watanabe, Kazunari Tagawa, Hidemitsu Uno, Dongho Kim
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS 15 (26) 10612 - 10615 1463-9076 2013 [Peer-reviewed]
     Scientific journal 
    In this study, we have investigated the shape-dependence of TPA cross-section values of two-dimensionally extended benzoporphyrin arrays to determine the relationship between the directionality of pi-conjugation pathways and TPA properties.
  • Hiroko Yamada, Yuji Yamaguchi, Ryuta Katoh, Takao Motoyama, Tatsuya Aotake, Daiki Kuzuhara, Mitsuharu Suzuki, Tetsuo Okujima, Hidemitsu Uno, Naoki Aratani, Ken-ichi Nakayama
    CHEMICAL COMMUNICATIONS 49 (99) 11638 - 11640 1359-7345 2013 [Peer-reviewed]
     Scientific journal 
    P-n junction solar cells based on anthradithiophene (ADT) as a p-type semiconductor were fabricated by using the photoprecursor method in which an alpha-diketone-type precursor was spin-coated and then transformed to ADT in situ by photoirradiation. Combination with PC71BM as an n-layer material led to 1.54% photoconversion efficiency.
  • Hiroki Uoyama, Hiroko Yamada, Tetsuo Okujima, Hidemitsu Uno
    HETEROCYCLES 86 (1) 515 - 534 0385-5414 2012/12 Scientific journal 
    Ethanonaphthoporphyrins with a halogen atom at the zeta position were prepared by the [3+1] porphyrin synthesis of halogen-substituted ethanobenz[f]isoindole with a tripyrrane derivative. The halogeno porphyrins were converted to the corresponding ethynyl and pinacolatoboronyl compounds by Sonogashira and borylation reactions, respectively. Suzuki, Sonogashira, and Glaser coupling reactions of these ethanonaphthoporphyrins gave bis-porphyrins connected with no atom, acetylene, and butadiyne, respectively. Retro Diels-Alder reaction of these bis-porphyrins brought about the conversion of bicyclo[2.2.2]octadiene (BCOD) to benzene moieties to give bis-naphthoporphyrins, quantitatively.
  • Tetsuo Okujima, Akiko Toda, Yoko Miyashita, Ayumi Nonoshita, Hiroko Yamada, Noboru Ono, Hidemitsu Uno
    HETEROCYCLES 86 (1) 637 - 648 0385-5414 2012/12 Scientific journal 
    Bis(azulenylethynyl)thiophenes, terthiophenes, and dithienothiophenes have been synthesized by the Pd-catalyzed cross-coupling of the corresponding diiodothiophenes with 1- and 6-ethynylazulenes under Sonogashira-Hagihara conditions.
  • Takaaki Yamamoto, Motoki Toganoh, Shigeki Mori, Hidemitsu Uno, Hiroyuki Furuta
    CHEMICAL SCIENCE 3 (11) 3241 - 3248 2041-6520 2012/11 Scientific journal 
    Peripherally pi-extended N-confused porphyrin rhenium complexes were synthesized by the rhenium-mediated reactions of N-confused porphyrins with 2-methyl azaarene and the structures were elucidated by X-ray crystallographic analyses. Extension of the pi-conjugation in the complexes was supported by the absorption spectra, electrochemical measurements and theoretical calculations.
  • Tetsuo Okujima, Tasuku Kikkawa, Haruyuki Nakano, Hiroshi Kubota, Nobumasa Fukugami, Noboru Ono, Hiroko Yamada, Hidemitsu Uno
    CHEMISTRY-A EUROPEAN JOURNAL 18 (40) 12854 - 12863 0947-6539 2012/10 [Peer-reviewed]
     Scientific journal 
    Bicyclo[2.2.2]octadiene (BCOD) fused azuliporphyrins were synthesized by 3+1 porphyrin synthesis of azulitripyrranes with diformylpyrroles. Subsequent retro-Diels-Alder reaction of the BCOD-fused azuliporphyrins afforded azulibenzo, azulidibenzo-, and azulitribenzoporphyrins 1-5. NMR and UV/Vis spectra, as well as nucleus-independent chemical shift (NICS) calculations revealed that 1-5 and their diprotonated dications exhibit relatively low porphyrinoid aromaticity, which was dependent on the position and number of fused benzene rings present.
  • Akio Kamimura, Tomomi Nokubi, Kotaro Nasu, Yasuko Takechi, Yuriko Ishihara, Kazunari Kato, Saori Noguchi, Masanori Watanabe, Masashi Shirai, Michinori Sumimoto, Hidemitsu Uno
    CHEMISTRY LETTERS 41 (9) 950 - 951 0366-7022 2012/09 Scientific journal 
    Quinone dimers are readily prepared quantitatively from 2-sulfanyl-1,4-dimethoxybenzene by oxidative treatment. The oxidative coupling progressed in a highly regioselective manner. Removal of O-protection and subsequent oxidation gave 5,5'-bis(sulfanylquinone) dimer in good yields. Physical properties of the dimer derivatives are also investigated.
  • Akio Kamimura, Hideki Matsu, Hiroyuki Suzukawa, Eisuke Sato, Michinori Sumimoto, Hidemitsu Uno
    CHEMISTRY LETTERS 41 (9) 984 - 986 0366-7022 2012/09 Scientific journal 
    One-pot treatment of commercially available 1,3,3-tributoxy-2-cyanopropene with 2 equivalents of primary aromatic amines readily afforded 1,5-diaryl-1,5-diaza-3-cyanopenta-1,3-dienes. UV properties varied as steric size of the orthosubstituent in the N-aryl units increased. X-ray crystallographic analyses indicated preferable conformation of these compounds, and the twist angles between 1,5-diazapentadiene and aromatic units were measured. The relationship between the twisted angles and UV absorptions was rationalized by MO calculation, and the UV peak wavelengths are useful for the estimation of the twisted angles. A novel tetracoordinate diaryl-1,5-diazapentadiene was prepared. UV spectrum for its lithium complex in CHCl3 supported that the complex had a twisted conformation of the aryl units because the two etharial oxygen atoms coordinated to lithium cation.
  • Hirofumi Nobukuni, Takuya Kamimura, Hidemitsu Uno, Yuichi Shimazaki, Yoshinori Naruta, Fumito Tani
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 85 (8) 862 - 868 0009-2673 2012/08 Scientific journal 
    Cyclic nickel and free-base porphyrin dimers (Ni-2-CPDpy and H-4-CPDpy) include [6,6]-phenyl-C-61-butyric acid methyl ester (PCBM) both in solution and in the crystals. In the crystal packing of the inclusion complex of Ni-2-CPDpy and PCBM, a nanotubular structure is constructed through the self-assembly of the porphyrin moiety. The PCBM molecules are linearly arranged in the inner channel of the nanotube to give a supramolecular peapod. On the other hand, in the crystal of the inclusion complex of H-4-CPDpy and PCBM, a dimeric structure of the PCBM molecules is formed through pi-pi interaction between their phenyl groups.
  • Quan Liu, Fan-Tai Kong, Tetsuo Okujima, Hiroko Yamada, Song-Yuan Dai, Hidemitsu Uno, Noboru Ono, Xiao-Zeng You, Zhen Shen
    TETRAHEDRON LETTERS 53 (26) 3264 - 3267 0040-4039 2012/06 Scientific journal 
    Bisdimethylfluorenylamino-based push-pull dyes bearing one or two benzo[c]thiophene and its precursor bicyclo[2.2.2]octadiene (BCOD) fused thiophene as it bridge have been synthesized. The effect of fused-ring on thiophene bridge for the spectroscopic and electrochemical properties of these dyes has been investigated. Dye-sensitized solar cells fabricated with these dyes show moderate photovoltaic properties. (C) 2012 Elsevier Ltd. All rights reserved.
  • Hiroshi Nozaki, Ken-ichiro Hayashi, Mikiko Kawai, Taichi Mitsui, Masahiro Kido, Hiroyuki Tani, Daisuke Takaoka, Hidemitsu Uno, Susumu Ohira, Atsuto Kuboki, Nobuyasu Matsuura
    NATURAL PRODUCT COMMUNICATIONS 7 (4) 427 - 430 1934-578X 2012/04 [Peer-reviewed]
     Scientific journal 
    Four new eremophilane-type sesquiterpenes, culcitiolides A-D, were isolated from the stem of Senecio culcitioides Sch. Bip (Asteraceae). Their structures were established by detailed 2D NMR spectroscopic and single-crystal X-ray experiments. These compounds were assessed for inhibitory activity against nuclear factor kappa B (NF-kappa B). Culcitiolides C and D at 20 mu M showed 97 and 100% inhibition of NF-kappa B activity, respectively.
  • Tatsuya Aotake, Shinya Ikeda, Daiki Kuzuhara, Shigeki Mori, Tetsuo Okujima, Hidemitsu Uno, Hiroko Yamada
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (9) 1723 - 1729 1434-193X 2012/03 Scientific journal 
    5,14-alpha-Diketopentacene, a structural isomer of 6,13-alpha-diketopentacene, was prepared from pentacene in three steps. In addition to the typical n-pi* absorption of the diketone moiety at around 468 nm and the anthracene-like absorption at 333, 349, and 367 nm, a broad absorption was observed at around 386 nm, which could be assigned to an intramolecular charge-transfer absorption from anthracene to the diketone moiety. 5,14-alpha-Diketopentacene could be converted into pentacene quantitatively by photoirradiation at 405 and 468 nm in toluene with quantum yields of 2.3 and 2.4%, respectively, and these values are higher than the quantum yield of 1.4% obtained for 6,13-alpha-diketopentacene irradiated at 468 nm. The quantum yields in acetonitrile were lowered to 0.33 and 0.28% with irradiation at 405 and 468 nm. The crystal structure of 5,14-alpha-diketopentacene showed a CH-pi interaction and pi-pi stacking between neighbouring anthracene and benzene moieties. The lower solubility of 5,14-alpha-diketopentacene compared with the 6,13-isomer could be explained by this crystal structure.
  • Takahiro Nakae, Ryuji Ohnishi, Yoshiharu Kitahata, Tatsuya Soukawa, Hisako Sato, Shigeki Mori, Tetsuo Okujima, Hidemitsu Uno, Hiroshi Sakaguchi
    TETRAHEDRON LETTERS 53 (13) 1617 - 1619 0040-4039 2012/03 Scientific journal 
    6,13-Diiododibenzo[a,h]anthracene and 5,8-diiodopicene were synthesized by AuCl-catalyzed double cyclization. The highly selective reaction yielded a new class of pen-halogenated fused aromatics. (C) 2012 Elsevier Ltd. All rights reserved.
  • Shin Ichi Nagaoka, Akiko Fujii, Megumi Hino, Mai Takemoto, Misaki Yasuda, Mariko Mishima, Keishi Ohara, Akane Masumoto, Hidemitsu Uno, Umpei Nagashima
    Journal of Physical Chemistry B 116 2338  1520-6106 2012/02
  • Cai Chenxin, Hiroki Uoyama, Mitsunori Nakamura, Hidemitsu Uno
    HETEROCYCLES 84 (2) 829 - 841 0385-5414 2012/01 Scientific journal 
    Esters of 4,9-dihydro-2H-benz[2,3-f] isoindole-1-carboxylate and 4,11-dihydro-2H-naphth[2,3-f]isoindole-1-carboxylate were prepared by the modified Barton-Zard reaction of 2,3-bis(phenylsulfonyl)-1,2,3,4-tetrahydro-naphthalene and anthracene with isocyanoacetate esters, respectively. The bis(phenylsulfonyl) derivatives were, in turn, prepared by the pericyclic reactions of the corresponding sultines with trans-1,2-bis(phenylsulfonyl)ethylene. The pyrrole esters were converted to the corresponding mono-naphthoporphyrin and mono-anthraporphyrin in good overall yields.
  • Xiu-Zhao Jiang, Chen-Xin Cai, Tao Liu, Hidemitsu Uno
    ORGANIC & BIOMOLECULAR CHEMISTRY 10 (15) 3110 - 3115 1477-0520 2012 [Peer-reviewed]
     Scientific journal 
    o-Quinodimethane (o-QDM) generated from benzosultine was used to extend the pyrrole system for the preparation of octabromo-tetranaphtho[2,3]porphyrins via oxidative aromatization. The properties of these bromoporphyrins were presented and chemical transformation via Pd-catalyzed Suzuki reaction was also effectively achieved.
  • Sabapathi Gokulnath, Motoki Toganoh, Keisuke Yamaguchi, Shigeki Mori, Hidemitsu Uno, Hiroyuki Furuta
    DALTON TRANSACTIONS 41 (20) 6283 - 6290 1477-9226 2012 [Peer-reviewed]
     Scientific journal 
    Singly N-confused [26] and [28]hexaphyrins (4, 5) with planar and twisted structures, respectively, were prepared via the acid catalyzed [3 + 3] condensation of N-confused and regular tripyrrane precursors. Huckel aromaticity is observed for [26]hexaphyrin, while the [28]hexaphyrin and its mono-Pd(II) complex exhibit "nonaromaticity" in spite of their Mobius-type structures, judging from the spectroscopic features and theoretical calculations.
  • Akio Kamimura, Koichiro Miyazaki, Shuzo Suzuki, Shingo Ishikawa, Hidemitsu Uno
    ORGANIC & BIOMOLECULAR CHEMISTRY 10 (22) 4362 - 4366 1477-0520 2012 [Peer-reviewed]
     Scientific journal 
    Optically active ent-calystegine B4 was prepared in 13 steps from commercially available chiral L-dimethyl tartrate. The synthesis was achieved by the Michael addition and the aldol reaction of nitromethane to form cycloheptanone in a stereoselective manner. Reduction of the nitro group in the presence of Boc(2)O accomplished an efficient conversion to amino cycloheptanone, which readily afforded the desired ent-calystegine B4.
  • Akio Kamimura, Shingo Ishikawa, Fumiaki Noguchi, Takaaki Moriyama, Masahiro So, Toshihiro Murafuji, Hidemitsu Uno
    CHEMICAL COMMUNICATIONS 48 (52) 6592 - 6594 1359-7345 2012 [Peer-reviewed]
     Scientific journal 
    Optically active stannolanes and trigonal bipyramidal penta-coordinated tin complexes were readily prepared by radical cyclization of N-propargylated chiral aza-Morita-Baylis-Hillman adducts induced by Bu3SnH. A translocated radical through the cyclization attacked the Bu3Sn group in an S(H)2 manner.
  • Chika Nozaki Kato, Yusuke Morii, Shota Hattori, Ryuta Nakayama, Yuki Makino, Hidemitsu Uno
    DALTON TRANSACTIONS 41 (33) 10021 - 10027 1477-9226 2012 [Peer-reviewed]
     Scientific journal 
    The synthesis and molecular structure of a monomeric diplatinum(II) complex composed of mono-lacunary alpha-Keggin polyoxometalate is described. The polyoxometalate, Cs-3[alpha-PW11O39-{cis-Pt(NH3)(2)}(2)]center dot 8H(2)O (Cs-1), afforded by a stoichiometric reaction of mono-lacunary Keggin polyoxotungstate with cis-diamminedichloroplatinum(II) in water, followed by crystallization from water, was obtained as analytically pure, homogeneous, yellow crystals. The compound Cs-1 was characterized by elemental analysis, thermogravimetric/differential thermal analysis (TG/DTA), Fourier transform infrared (FTIR) and UV-visible spectroscopy, solution H-1 and P-31 nuclear magnetic resonance (NMR), and X-ray crystallography. The single-crystal X-ray structure analysis revealed that the two cis-platinum(II) moieties, [cis-Pt(NH3)(2)](2+), were coordinated each to two oxygen atoms in a mono-vacant site of [alpha-PW11O39](7-) with asymmetric configuration, resulting in an overall C-1 symmetry. Furthermore, hydrogen evolution from an EDTA center dot 2Na (ethylenediamine tetraacetic acid disodium salt) aqueous solution under visible-light irradiation (>= 400 nm) was achieved by using polyoxoanion 1 and titanium dioxide.
  • Mitsunori Nakamura, Hiroyuki Tahara, Kohtaro Takahashi, Toshi Nagata, Hiroki Uoyama, Daiki Kuzuhara, Shigeki Mori, Tetsuo Okujima, Hiroko Yamada, Hidemitsu Uno
    ORGANIC & BIOMOLECULAR CHEMISTRY 10 (34) 6840 - 6849 1477-0520 2012 [Peer-reviewed]
     Scientific journal 
    Benzene-fused bis-(borondipyrromethene)s (bis-BODIPYs) were synthesized by retro-Diels-Alder reaction of the corresponding bicyclo[2.2.2]octadiene-fused (BCOD-fused) bis-BODIPYs, which were, in turn, prepared from 4,8-ethano-4,8-dihydropyrrolo[3,4-f]isoindole derivatives. The pi-fused bis-BODIPY chromophores were designed to show intensive absorption and strong fluorescence in the near-infrared region and not to have any strong absorption in the visible region. A 6,10-dibora-5a,6a,9a,10a-tetraaza-s-indaceno[2,3-b:6,5-b']difluorene derivative (syn-bis-benzoBODIPY) obtained by a thermal retro-Diels-Alder reaction of the corresponding BCOD-fused BODIPY dimer has strong absorption and emission bands at 775 and 781 nm, respectively. The absolute quantum yield is 0.36. The absorption is more than 5.0 times stronger than other absorptions observed in the visible region. In the case of 6,15-dibora-5a,6a,14a,15a-tetraaza-s-indaceno[2,3-b:6,7-b']difluorene derivatives (anti-bis-benzoBODIPY), the absorption and emission maxima exceed 840 nm.
  • Motoki Toganoh, Yasunori Kawabe, Hidemitsu Uno, Hiroyuki Furuta
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 51 (35) 8753 - 8756 1433-7851 2012 [Peer-reviewed]
     Scientific journal
  • Hiroko Yamada, Chika Ohashi, Tatsuya Aotake, Shuhei Katsuta, Yoshihito Honsho, Hiroo Kawano, Tetsuo Okujima, Hidemitsu Uno, Noboru Ono, Shu Seki, Ken-ichi Nakayama
    CHEMICAL COMMUNICATIONS 48 (90) 11136 - 11138 1359-7345 2012 [Peer-reviewed]
     Scientific journal 
    Hole mobility was evaluated by top-contact bottom gate field effect transistor and time resolved microwave conductivity measurements in 2,6-dithienylanthracene and hexyl-substituted 2,6-dithienylanthracene films prepared by spin-coating of their alpha-diketone precursors followed by photoirradiation, revealing enough high potentials for semiconducting films with charge carrier mobilities of 0.8-0.9 cm(2) V-1 s(-1) in the photo-irradiated films.
  • Hirofumi Nobukuni, Takuya Kamimura, Hidemitsu Uno, Yuichi Shimazaki, Yoshinori Naruta, Fumito Tani
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 84 (12) 1321 - 1328 0009-2673 2011/12 Scientific journal 
    Cyclic nickel and free-base porphyrin dimers (Ni-2-CPDpy and H-4-CPDpy) include fullerene C-70 both in solution and in the crystals. Based on the C-13 NMR spectra in solution, the included C(70 molecu)le inside the cavity of Ni-2-CPDpy shows both end-on and side-on orientations, whereas the C-70 molecule within H-4-CPDPy has only a side-on orientation toward the porphyrin rings. X-ray crystallography revealed both "end-on" and "side-on" orientations of C-70 in the crystal structure of the inclusion complex of Ni-2-CPDPy and C-70. This is the first example of an X-ray crystallographic determination for an end-on orientation of C-70 cocrystallized with porphyrins. On the other hand, only a side-on orientation of C-70 was observed in the crystal structure of the complex of H-4-CPDPy and C-70. Further, a zigzag array of C-70 molecules through van der Waals contacts with each other is formed along the monoclinic b axis in the latter crystal.
  • Daiki Kuzuhara, Hiroko Yamada, Shigeki Mori, Tetsuo Okujima, Hidemitsu Uno
    JOURNAL OF PORPHYRINS AND PHTHALOCYANINES 15 (9-10) 930 - 942 1088-4246 2011/09 Scientific journal 
    A series of benzoporphycenes and naphthoporphycenes and their zinc complexes were prepared from bicyclo[2.2.2]octadiene fused porphycenes by a retro-Diels-Alder reaction and their photophysical properties were studied. Free-base tetranaphthoporphycene was not soluble in common organic solvents, but zinc tetranaphthoporphycene was slightly soluble in pyridine and showed B- and Q-bands at 507 and 690 nm, respectively. Dinaphthoporphycene showed broad B- and Q-bands due to its lower symmetry. Tetrabenzo-, dibenzo-, and dinaphthoporphycenes showed fluorescence at 673, 654, and 670 nm with quantum yields of 0.32, 0.42, and 0.31, respectively, although their precursors were non-fluorescent. Zinc complexes of tetrabenzo-, dibenzo-, tetranaphtho-, dinaphthoporphycenes and their bicyclo[2.2.2]octadiene-fused precursors revealed moderate fluorescence with quantum yields of 0.15-0.37. The crystal structures of tetrabenzo-and dibenzoporphycenes showed herringbone structures, while the zinc tetrabenzoporphycene showed a hexagonal box-structure with six pyridine ligands inside.
  • Hidemitsu Uno, Mina Furukawa, Akiko Fujimoto, Hiroki Uoyama, Hajime Watanabe, Tetsuo Okujima, Hiroko Yamada, Shigeki Mori, Makoto Kuramoto, Tatsunori Iwamura, Noriyuki Hatae, Fumito Tani, Naoki Komatsu
    JOURNAL OF PORPHYRINS AND PHTHALOCYANINES 15 (9-10) 951 - 963 1088-4246 2011/09 Scientific journal 
    Facing zinc bisporphyrins connected with diethanoanthracene and diethanonaphthacene (syn-1 and syn-2) are prepared by double [3+1] porphyrin synthesis of tripyrranedicarbaldehyde with syn-5,11-dimethoxy-4,6,10,12-tetrahydro-4,12;6,10-diethanoanthracene[2,3-c;7,8-c']dipyrrole and syn-4,7,11,14-tetrahydro-4,14;7,11-diethanonaphthacene[2,3-c;8,9-c']dipyrrole. These bisporphyrins contain large clefts with different sizes capable for complexation with fullerenes such as C-60 and C-70. These designed syn-oriented bisporphyrins serve as effective and selective molecular tweezers for C-70. Binding affinity of the zinc bisporphyrins, namely, syn-1 and syn-2, towards C-60 and C-70 in solution is determined by employing UV-vis spectrophotometric technique. Values of binding constants (K) in toluene for the non-covalent complexes of syn-1 with C-60 and C-70 are estimated to be 3.1(4) x 10(4) and 5.0(2) x 10(5) M-1, respectively, and those of syn-2 with C-60 and C-70 are enumerated to be 2.1(4) x 10(4) and 1.70(13) x 10(5) M-1, respectively. Binding of C-60 and C-70 in the clefts of syn-1 and syn-2 is clearly demonstrated by the crystal structures of C-60/syn-1, C-70/syn-1, C-60/syn-2, and C-70/syn-2 complexes. In the crystal structures with C-70, the directions of the long axis of C-70 are found to be quite different: in the case of C-70/syn-1 complex the axis lies perpendicularly to the line connecting two zinc atoms; however, for the C-70/syn-2 complex, the axis occupies in-plane to the same line. Both the clefts of syn-1 and syn-2 are induced to fit the included fullerenes by domed out-of-plane distortion of porphyrin rings. Moreover, the bicyclo[2.2.2]octadiene moieties of syn-1 are widened by complexation with the fullerenes, while the same moieties of syn-2 are narrowed by the complexation. Therefore, syn-1 catches the fullerenes at the shallow part of the cleft. On the other hand, syn-2 catches the fullerenes at the bottom part of the cleft. NMR experiments of the complexes in THF-d(8) also support these orientations even in solution.
  • Yusuke Iima, Daiki Kuzuhara, Zhao-Li Xue, Hidemitsu Uno, Seiji Akimoto, Hiroko Yamada, Keisuke Tominaga
    CHEMICAL PHYSICS LETTERS 513 (1-3) 67 - 71 0009-2614 2011/09 Scientific journal 
    Excited state dynamics of benzotriphyrin(2.1.1) is investigated by time-resolved fluorescence techniques. The fluorescence quantum yield is found to be 0.005, and the lifetime of the excited state of triphyrin(2.1.1) is found to be 140 ps. Fluorescence anisotropy clearly shows that intramolecular proton transfer does not occur within the excited state lifetime. The short lifetime of the excited state is due to fast internal conversion (IC) from the S(1) state, and to the nonplanarity of the macrocycle enhancing IC decay pathways. (C) 2011 Elsevier B. V. All rights reserved.
  • Hiroko Yamada, Daiki Kuzuhara, Shuhei Katsuta, Tetsuo Okujima, Hidemitsu Uno
    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN 69 (7) 802 - 813 0037-9980 2011/07 Scientific journal 
    This paper focuses on the synthesis of new aromatic compounds by thermal, photochemical, or oxidative cleavage reaction of the corresponding precursors. The precursor-methods are useful for the derivatization of the non-soluble aromatic compounds. We have applied retro Diels-Alder reactions for the preparation of new pi-expanded porphyrinoid compounds such as [14] tribenzo-triphyrin (2.1.1), tetrabenzoporphycene, dodecasubstituted porphycene, tetraanthraporphyin, butadiyne-linked tetrabenzoporphyrin dimer, and so on. We have investigated the photocleavage synthesis of pentacenes from the corresponding alpha-diketone precursors. This photoreaction enabled us to prepare 1,4,8,11-tetrasubstituted pentacene. The synthesis of new pentacene derivatives with electron-withdrawing substituents at 6,13-positions by oxidative cleavage reaction will be also reported.
  • Tetsuo Okujima, Guangnan Jin, Saika Otsubo, Shinji Aramaki, Noboru Ono, Hiroko Yamada, Hidemitsu Uno
    JOURNAL OF PORPHYRINS AND PHTHALOCYANINES 15 (7-8) 697 - 703 1088-4246 2011/07 Scientific journal 
    Bicyclo[2.2.2]octadiene(BCOD)-fused diazaporphyrin was synthesized by the reaction of BCOD-fused dipyrromethane with sodium nitrite in acetic acid/ethanol in the presence of copper(II) acetylacetonate. This soluble precursor was converted into the semiconducting thin film of (tetrabenzodiazaporphyrinato)copper(II) by heating after fabrication via spin-coating.
  • Yuya Tornimori, Tetsuo Okujima, Tomoko Yano, Shigeki Mori, Noboru Ono, Hiroko Yamada, Hidemitsu Uno
    TETRAHEDRON 67 (18) 3187 - 3193 0040-4020 2011/05 Scientific journal 
    A pi-expanded BODIPY dye with an intramolecular boronate skeleton was synthesized by retro Diets-Alder reaction of the bicyclo[2.2.2]octadiene (BCOD)-fused BODIPY and the subsequent O-chelation. The photophysical and electrochemical properties were examined by UV-vis, fluorescence, CV measurements, and DFT calculation. This BODIPY exhibited the absorption and emission over a visible-NIR region at 600-850 nm. O-chelated BODIPY showed a bathocromic shift compared to F-BODIPYs. This dye showed a bright fluorescence emission at 733 nm with the high phi value of 0.58. (C) 2011 Elsevier Ltd. All rights reserved.
  • Pyosang Kim, Jooyoung Sung, Hiroki Uoyama, Tetsuo Okujima, Hidemitsu Uno, Dongho Kim
    JOURNAL OF PHYSICAL CHEMISTRY B 115 (14) 3784 - 3792 1520-6106 2011/04 [Peer-reviewed]
     Scientific journal 
    We have investigated the role of fused benzo rings on the electronic structures and intramolecular energy relaxation dynamics in a series of benzoporphyrins (Bpl, syn-Bp2, anti-Bp2, Bp3, and Bp4) by using time-resolved fluorescence measurements and theoretical calculations. Interestingly, even though anti- and syn-Bp2 have the same number of fused anti-Bp2 benzo rings, in the respective absorption spectra, shows an obvious splitting of B(x) (Q(x)) and B(y) (Q(y)) states, whereas syn-Bp2 exhibits degenerate B and Q bands. These features provide two dynamical models for the effect of the position of substituted benzo rings on the intramolecular energy relaxation dynamics. syn-Bp2 gives rise to similar intrarnolecular dynamics from the B state to the Q state in the case of ZnTPP having Do molecular symmetry. On the other hand, anti-Bp2 shows split B and Q bands in the order B(y) > B(x) > Q(x) > Q(y), which leads a superimposition of the Q(x) (0,0) and Q(y) (1,0) bands. This overlap generates a strong coupling between these two states, which results in a direct internal conversion from B(x) (0,0) to Q(y) (0,0). This observation suggests that the anti-type fused position of benzo rings leads to a new mechanism in internal conversion from the B to the Q state. On the basis of this work, further insight was obtained into the effect of fused benzo rings on the photophysical properties of benzoporphyrins, providing a detailed understanding of the structure-property relationship in a series of benzoporphyrins.
  • Shuhei Katsuta, Daichi Miyagi, Hiroko Yamada, Tetsuo Okujima, Shigeki Mori, Ken-ichi Nakayama, Hidemitsu Uno
    ORGANIC LETTERS 13 (6) 1454 - 1457 1523-7060 2011/03 [Peer-reviewed]
     Scientific journal 
    5,12-Dicyanonaphthacene and 6,13-dicyanopentacene have been synthesized for the first time. The LUMO and HOMO levels are deepened as predicted and fabricated organic field-effect transistors (OFETs) showed ambipolar responses with carrier mobilities of 10(-3) cm(2)/V.s.
  • Daiki Kuzuhara, Hiroko Yamada, Keiko Yano, Tetsuo Okujima, Shigeki Mori, Hidemitsu Uno
    CHEMISTRY-A EUROPEAN JOURNAL 17 (12) 3376 - 3383 0947-6539 2011/03 [Peer-reviewed]
     Scientific journal 
    The synthesis of dodecasubstituted porphycenes has not been reported, to date. Herein, the preparation of tetramethyloctaethylporphycene by a McMurry-type coupling of 3,3', 4,4'-tetraethyl-5,5'-diformyl-2,2'-bipyrrole was attempted at first, but dodecasubstituted porphycene was not successfully obtained and only pyrrolocyclophene was obtained. The structure of the pyrrolocyclophene was determined by H-1 NMR spectroscopy, FAB MS, and X-ray crystal-structure analysis. The pyrrolocyclophene was not successfully oxidized to porphycene. Then, the McMurry-type coupling of bicyclo[2.2.2]octadiene (BCOD)-fused 5,5'diacyl-2,2'-bipyrroles was performed and tetra-meso-octa-beta-substituted (dodecasubstituted) porphycenes were successfully obtained for the first time. The structures were determined by H-1 NMR spectroscopy and X-ray crystal-structure analysis. The crystal structures and NMR spectra were compared carefully with octasubstituted porphycenes, and there was a good correlation between the position of the substituents, the N1-N2 and N1-N4 distances of the porphycene inner nitrogen atoms, and NMR chemical shifts of the inner NH protons, which expressed the strength of N-H center dot center dot center dot N hydrogen bonding between N1 and N2. These results suggested that the BCOD structure was relatively compact compared with common alkyl groups and that was why the dodecasubstituted porphycenes were available this time. UV/Vis absorption and fluorescence properties are also discussed.
  • Seizo Sato, Fumie Iwata, Jiro Takeo, Hiroyuki Kawahara, Makoto Kuramoto, Hidemitsu Uno
    CHEMISTRY LETTERS 40 (2) 186 - 187 0366-7022 2011/02 Scientific journal 
    A new cytotoxic imidazole alkaloid, stellettazole D, containing norsesquiterpene and aminopropylimidazolium units, has been isolated from the marine sponge Jaspis duoaster. The structure of stellettazole D was assigned on the basis of NMR, mass spectrometry, and IR spectral data. Stellettazole D has moderate cytotoxicity against a limited number of tumor cells.
  • Debabrata Pal, Mina Furukawa, Naoki Komatsu, Hidemitsu Uno, Sumanta Bhattacharya
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 78 (1) 185 - 190 1386-1425 2011/01 Scientific journal 
    The present paper reports the photophysical investigations of a designed bisporphyrin (1), and its supramolecular complexes with C-60 and C-70 in toluene medium. UV-vis studies reveal appreciable ground state interaction between fullerenes and 1. The stoichiometry of the fullerene complexes of 1 is found to be 1:1. Steady state fluorescence studies elicit quenching of fluorescence oil in the presence of fullerenes. The binding constants of the C-60/1 and C-70/1 complexes are estimated to be 3760 and 31,222.5 dm(3) mol(-1), respectively. Time resolved emission studies establish relatively long-lived charge separated state for the C-70/1 complex. Molecular mechanics calculations in vacuo evoke the stereoscopic structures of the fullerene/1 complexes and interpret the stability difference between C-60 and C-70 complexes of 1 in terms of heat of formation values. (C) 2010 Elsevier B.V. All rights reserved.
  • Hisako Sato, Hidemitsu Uno, Haruyuki Nakano
    DALTON TRANSACTIONS 40 (6) 1332 - 1337 1477-9226 2011 Scientific journal 
    Vibrational circular dichroism (VCD) spectra were measured on the chloroform solutions of a series of mixed-ligand diamagnetic Co(III) complexes, [Co(tfac)(n)(acac)(3-n)] (n = 0-3, tfac = 1,1,1-trifluoro-2,4-pentanedionato; acac = acetylacetonato). Distinct differences were observed in the VCD spectra among the geometrical isomers of the same ligand composition. Such differentiation was hardly possible by their infra-red spectra alone. The structural identification of these isomers was performed in conjunction with DFT calculations.
  • Daiki Kuzuhara, Hiroko Yamada, ZhaoLi Xue, Tetsuo Okujima, Shigeki Mori, Zhen Shen, Hidemitsu Uno
    CHEMICAL COMMUNICATIONS 47 (2) 722 - 724 1359-7345 2011 [Peer-reviewed]
     Scientific journal 
    The metal-free and meso-free [14]triphyrin(2.1.1) compound was successfully prepared based on the intramolecular McMurry coupling reaction of diformyl-tripyrrane in 16% yield, and was converted to the bowl-shaped Mn(I)(TriP)(CO)(3) and Re(I)(TriP)(CO)(3).
  • Tetsuo Okujima, Guangnan Jin, Naoki Matsumoto, John Mack, Shigeki Mori, Keishi Ohara, Daiki Kuzuhara, Chie Ando, Noboru Ono, Hiroko Yamada, Hidemitsu Uno, Nagao Kobayashi
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 50 (25) 5698 - 5702 1433-7851 2011 [Peer-reviewed]
     Scientific journal
  • Shuhei Katsuta, Kazuki Tanaka, Yukihiro Maruya, Shigeki Mori, Sadahiro Masuo, Tetsuo Okujima, Hidemitsu Uno, Ken-ichi Nakayama, Hiroko Yamada
    CHEMICAL COMMUNICATIONS 47 (36) 10112 - 10114 1359-7345 2011 [Peer-reviewed]
     Scientific journal 
    Novel bisimide-fused acenes were synthesized via bismuth triflate mediated double-cyclization reaction of acid chlorides and isocyanates. Their optical and electrical properties revealed significantly smaller HOMO-LUMO gaps compared with those of their parent acenes. Fabricated OFET based on tetracene bisimide showed n-type OFET outputs.
  • Sabapathi Gokulnath, Keisuke Yamaguchi, Motoki Toganoh, Shigeki Mori, Hidemitsu Uno, Hiroyuki Furuta
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 50 (10) 2302 - 2306 1433-7851 2011 [Peer-reviewed]
     Scientific journal
  • Hiroko Yamada, Kei Ohkubo, Daiki Kuzuhara, Tetsuro Takahashi, Atula S. D. Sandanayaka, Tetsuo Okujima, Keishi Ohara, Osamu Ito, Hidemitsu Uno, Noboru Ono, Shunichi Fukuzumi
    JOURNAL OF PHYSICAL CHEMISTRY B 114 (45) 14717 - 14728 1520-6106 2010/11 Scientific journal 
    Free base and zinc porphyrins are linked with fullerene (C(60)) through beta,beta`-pyrrolic positions rather than meso-positions by Diels-Alder reaction of monoanthraporphyrins (H(2)P-mA and ZnP-mA) and C(60) to afford a pi-expanded free base porphyrin-fullerene dyad (H(2)P-C(60)) and its zinc porphyrin-fullerene dyad (ZnP-C(60)) in 86 and 51% yield, respectively The X-ray crystallographic analysis of ZnP-C(60) showed two comma-shaped swirls-like structure in a unit cell The intramolecular center-to-center and edge-to-edge distances between the porphyrin and fullerene moieties were 11 5 and 2 5 angstrom, respectively The porphyrins and fullerenes were packed in layer-by-layer structure and the porphyrins lied down in parallel The Intermolecular center-to-center distances between the neighboring fullerenes were 10 252, 10028, and 10 129 angstrom, which were less than typical van der Waals distance and the pi-pi interaction spread two-dimensionally The energy of the charge-separated (CS) state of ZnP-C(60) (1 11 eV) determined by differential-pulse voltammetry measurements in benzonitrile is significantly lower than those of zinc porphyrin-C(60) dyads linked at meso positions because of the low oxidation potential of the a-expanded ZnP moiety The CS energy of ZnP-C(60) in a nonpolar solvent such as toluene (1 40 V) is lower than the triplet excited state of C(60) ((3)C(60)*), enabling us to attain a longed lived triplet CS state (8 1 mu s) in toluene, detected by nanosecond laser flash photolysis experiments The distance between unpaired electrons in the triplet CS state was determined by the EPR spectrum to be 9 1 angstrom, which agreed with the distance between a zinc atom of the porphyrin and a carbon edge of C(60) in the crystal structure of ZnP-C(60) The rate constants of photoinduced electron transfer and back electron transfer of H(2)P-C(60) and ZnP-C(60), which were determined by femtosecond and nanosecond laser flash photolysis measurements, were analyzed in light of the Marcus theory of electron transfer
  • Tetsuo Okujima, Yuya Tomimori, Jun Nakamura, Hiroko Yamada, Hidemitsu Uno, Noboru Ono
    TETRAHEDRON 66 (34) 6895 - 6900 0040-4020 2010/08 Scientific journal 
    A series of pi-expanded boron-dipyrromethenes (BODIPYs) fused with aromatic rings at beta,beta-positions, such as benzene, acenaphthylene, and benzofluoranthene were prepared by the reaction of BF(3)center dot OEt(2) with bicyclo[2.2.2]octadiene-fused dipyrromethene and the subsequent retro Diels-Alder reaction. These BODIPYs exhibited the absorptions and the fluorescence emissions over wide range of visible-near infrared region at 500-800 nm. BODIPYs composed of two fluorantho[8,9-f]isoindoles absorbed and emitted at red-region over 750 nm with absolute fluorescence quantum yield (Phi(f)) of ca. 0.3, although they are unstable under air in room light. BODIPY composed fluorantho[8,9-f]isoindole and acenaphtho [1,2-c]pyrrole was stable and showed a bright fluorescence emission at 695 nm with high Phi(f) of 0.70. (C) 2010 Elsevier Ltd. All rights reserved.
  • Hiroki Uoyama, Hiroko Yamada, Tetsuo Okujima, Hidemitsu Uno
    TETRAHEDRON 66 (34) 6889 - 6894 0040-4020 2010/08 Scientific journal 
    15-Acetoxy- and 15-hydroxy-6,13-dihydro-6,13-ethanopentacenes sublimed over 300 degrees C and no pentacene was formed below the temperature. The precursors bearing chlorinated epithiomethano bridges suffered complicated decomposition to give oligomeric pentacene derivatives. The precursor bearing an epithio-oxomethano bridge underwent smooth and clean conversion to pentacene by heat or light. An organic field-effect transistor fabricated by the spin-coating method of the precursor followed by light irradiation at 120 degrees C showed a good FET performance of mu=2.5 x 10(-2) cm(2) V-1 s(-1) and on/off ratio=3.8 x 10(4). (C) 2010 Elsevier Ltd. All rights reserved.
  • Tetsuo Okujima, Tasuku Kikkawa, Saori Kawakami, Yusuke Shimizu, Hiroko Yamada, Noboru Ono, Hidemitsu Uno
    TETRAHEDRON 66 (35) 7213 - 7218 0040-4020 2010/08 Scientific journal 
    Bicyclo[2.2.2]octadiene(BCOD)-fused trithiasapphyrin was prepared by 3+2 condensation of BCOD-fused thiatripyrrane with BCOD-fused bithiophene. The BCOD-fused trithiasapphyrin was successfully converted to pentabenzo[b,g,l,q,v]sapphyrin by the thermal retro-Diels-Alder reaction. In this case, trithiapentabenzo[b,g,l,q,v]- and trithiadibenzo[g,q]sapphyrins were selectively prepared by control of the temperature in the thermal retro-Diels-Alder reaction. (C) 2010 Elsevier Ltd. All rights reserved.
  • Shingo Ishikawa, Fumiaki Noguchi, Hidemitsu Uno, Akio Kamimura
    TETRAHEDRON LETTERS 51 (17) 2329 - 2331 0040-4039 2010/04 Scientific journal 
    The intramolecular Pauson-Khand reaction of aza-Baylis-Hillman adducts, which were prepared through the thio-Michael/imino-aldol domino reaction of optically active sulfinimines, was examined and gave optically active cis- and trans-pyrrolidine-fused cyclopentenones in a stereoselective manner. (C) 2010 Elsevier Ltd. All rights reserved.
  • Jun Nakamura, Tetsuo Okujima, Yuya Tomimori, Naoki Komobuchi, Hiroko Yamada, Hidemitsu Uno, Noboru Ono
    HETEROCYCLES 80 (2) 1165 - 1175 0385-5414 2010/03 Scientific journal 
    Tetrabenzoporphyrins fused with fluoranthenes were prepared by the retro Diels-Alder reaction of the precursors composed of a porphyrin and four fluoranthenes connected with bicyclo[2.2.2]octadiene (BCOD). These porphyrins exhibited the Soret (480-494 nm, epsilon = 243,000-277,000) and intense Q bands (739-760 nm, epsilon = 375,000-509,000). Free bases and Zn complexes of them fluoresce at 760 nm and 746 nm with small Storks shifts and high quantum yields of 30 and 10 %, respectively.
  • Shuhei Katsuta, Hiroko Yamada, Tetsuo Okujima, Hidemitsu Uno
    TETRAHEDRON LETTERS 51 (10) 1397 - 1400 0040-4039 2010/03 Scientific journal 
    The syntheses of 1,4,8,11-tetraphenylpentacene and 1,4,8,11-tetra(2'-thienyl)pentacene are described via photodecarbonylation of the corresponding alpha-diketone precursors. (C) 2010 Elsevier Ltd. All rights reserved.
  • Hiroko Yamada, Daiki Kuzuhara, Kei Ohkubo, Tetsuro Takahashi, Tetsuo Okujima, Hidemitsu Uno, Noboru Ono, Shunichi Fukuzumi
    JOURNAL OF MATERIALS CHEMISTRY 20 (15) 3011 - 3024 0959-9428 2010 Scientific journal 
    A new alpha-diketoporphyrin and the corresponding Pd complex were prepared from the monoanthroporphyins and their photochemical properties were investigated by measurements of absorption and emission spectra, fluorescence lifetimes, laser flash photolysis, cyclic voltammetry, and theoretical calculations. Intramolecular electron transfer from the porphyrin singlet excited state to the diketone moiety was observed for the free base alpha-diketoporphyrin in benzonitrile, but this was not observed in toluene. Photoreactivity of the alpha-diketoporphyrins was also examined by irradiation at the Soret and Q bands. When the Soret band of the freebase alpha-diketoporphyrin was irradiated, cleavage of the diketone moiety occurred to afford the monoanthroporphyrin with the release of two CO molecules quantitatively in both benzonitrile and toluene. When the Q band of the freebase alpha-diketoporphyrin was irradiated, no photocleavage reaction occurred in toluene. In contrast to the freebase alpha-diketoporphyrin, the photocleavage reaction of the Pd complex occurred with irradiation at the Q band as well as the Soret band to afford the monoanthroporphyrin quantitatively in toluene. The photocleavage reaction proceeded much more effectively in toluene than in benzonitrile. The occurrence of rapid photoinduced electron transfer from the singlet excited state porphyrin to the diketone moiety, which was detected by femtosecond laser flash photolysis measurements, results in a significant decrease in the singlet excited state lifetime, prohibiting the photocleavage reaction in benzonitrile. Thus, the Pd alpha-diketoporphyrin can act as an excellent precursor for the corresponding acene in toluene. The photocleavage process provides a convenient and inexpensive method to make the thin film.
  • Hiroki Uoyama, Kil Suk Kim, Kenji Kuroki, Jae-Yoon Shin, Toshi Nagata, Tetsuo Okujima, Hiroko Yamada, Noboru Ono, Dongho Kim, Hidemitsu Uno
    CHEMISTRY-A EUROPEAN JOURNAL 16 (13) 4063 - 4074 0947-6539 2010 Scientific journal 
    Tetrameric porphyrin formation of 2-hydroxymethylpyrrole fused with porphyrins through a bicyclo[2.2.2]octadiene unit gave bicyclo[2.2.2]octadiene-fused porphyrin pentamers. Thermal conversion of the pentamers gave fully pi-conjugated cruciform porphyrin pentamers fused with benzene units in quantitative yields. UV/Vis spectra of fully pi-conjugated porphyrin pentamers showed one very strong Q absorption and were quite different from those of usual porphyrins. From TD-DFT calculations, the HOMO level is 0.49 eV higher than the HOMO-1 level. The LUMO and LUMO + 1 levels are very close and are lower by more than 0.27 eV than those of other unoccupied MOs. The strong Q absorption was interpreted as two mutually orthogonal single-electron transitions (683 nm: 86%, HOMO -> LUMO; 680 nm: 86%, HOMO -> LUMO + 1). The two-photon absorption (TPA) cross section value (sigma((2))) of the benzene-fused porphyrin pentamer was estimated to be 3900 GM at 1500 nm, which is strongly correlated with a cruciform molecular structure with multidirectional pi-conjugation pathways.
  • Guangnan Jin, Tetsuo Okujima, Yusuke Hashimoto, Hiroko Yamada, Hidemitsu Uno, Noboru Ono
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS 185 (5-6) 1108 - 1116 1042-6507 2010 Scientific journal 
    This article describes the preparation of (ethylenedithio)bicyclo[2.2.2]octadiene-fused porphyrins 13 and 14a,b as soluble precursors of 2,3-dihydrobenzo[1,4]dithiin-fused porphyrins and the retro Diels-Alder conversion of the precursors 13 and 14a,b.
  • Masatoshi Ishida, Satoru Karasawa, Hidemitsu Uno, Fumito Tani, Yoshinori Naruta
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 49 (34) 5906 - 5909 1433-7851 2010 Scientific journal 
    (Figure Presented) Acid does the trick: A novel 1,10-phenanthroline- embedded sapphyrin analogue 1 (see scheme; R = COOEt, Ar = p-tolyl) bearing meso alkylidenyl double bonds has been synthesized. Interestingly, the protonated form of! ([1-3 H]3+) exhibits singlet biradicaloid character. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
  • Hirofumi Nobukuni, Yuichi Shimazaki, Hidemitsu Uno, Yoshinori Naruta, Kei Ohkubo, Takahiko Kojima, Shunichi Fukuzumi, Shu Seki, Hayato Sakai, Taku Hasobe, Fumito Tani
    CHEMISTRY-A EUROPEAN JOURNAL 16 (38) 11611 - 11623 0947-6539 2010 Scientific journal 
    A cyclic free-base porphyrin dimer H-4-CPDPy (CPD = cyclic porphyrin dimer) linked by butadiyne moieties bearing 4-pyridyl groups self-assembles to form a novel porphyrin nanotube in the crystalline state. The cyclic molecules link together through non-classical C-H center dot center dot center dot N hydrogen bonds and pi-pi interactions of the pyridyl groups along the crystallographic a axis. H-4-CPDPy includes a C-60 molecule in its cavity in solution. In the crystal structure of the inclusion complex (C-60 subset of H-4-CPDPy), the dimer "bites" a C-60 molecule by tilting the porphyrin rings with respect to each other, and there are strong pi-pi interactions between the porphyrin rings and C-60. The included C-60 molecules form a zigzag chain along the crystallographic b axis through van der Waals contacts with each other. Femtosecond laser flash photolysis of C-60 subset of H-4-CPDPy in the solid state with photoexcitation at 420 nm shows the formation of a completely charge-separated state {H-4-CPDPy center dot+ + C-60(center dot-)}, which decays with a lifetime of 470 Ps to the ground state. The charge-carrier mobility of the single crystal of C-60 subset of H-4-CPDPy was determined by flash photolysis time-resolved microwave conductivity (FP-TRMC) measurements. C-60 subset of H-4-CPDPy has an anisotropic charge mobility (Sigma mu=0.16 and 0.13 cm(2)V(-1) s(-1)) along the zigzag chain of C-60 (which runs at 45 degrees and parallel to the crystallographic b axis). To construct a photoelectro-chemical cell, C-60 subset of H-4-CPDPy was deposited onto nanostructured SnO2 films on a transparent electrode. The solar cell exhibited photovoltaic activity with an incident photon to current conversion efficiency of 17%.
  • Toshiyuki Itoh, Manabu Kanbara, Shino Nakajima, Yusuke Sakuta, Shuichi Hayase, Motoi Kawatsura, Takashi Kato, Kazutoshi Miyazawa, Hidemitsu Uno
    JOURNAL OF FLUORINE CHEMISTRY 130 (12) 1157 - 1163 0022-1139 2009/12 Scientific journal 
    The synthesis of a novel spiro type gem-difluorocyclopropane building block, 1, 1,7,7-tetrafluoro-2,8-bis(hydroxymethyl)dispiro[2.2.2.2]decane(1), has been accomplished in optically pure form using chemo-enzymatic reaction protocol. Various types of diesters or dialkyl ether were prepared from diol (+)-1 or(-)-1 in optically active form and their helical twisting power(HTP) was evaluated by addition of 1.0 wt% to a non-chiral nematic liquid crystal host. Although their HTP values were not significant, all compounds showed liquid crystal property with SmC* phase when they were dissolved (20 wt%) in achiral nematic host liquid crystal. (C) 2009 Elsevier B.V. All rights reserved.
  • Satoshi Ito, Le Thanh Phong, Takuya Komatsu, Nagisa Igarashi, Saika Otsubo, Yoshimasa Sakai, Akira Ohno, Shinji Aramaki, Yousuke Tanaka, Hidemitsu Uno, Toru Oba, Kazuhisa Hiratani
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (31) 5373 - 5382 1434-193X 2009/11 Scientific journal 
    meso-Chlorinated bicyclo[2.2.2]octadiene-fused porphyrins 2 (Cl(n)TBCODPs; n = 1-4) have been synthesized by chlorination of the free base TBCODP-H(2) (1-H(2)) using N-chlorosuccinimide (NCS). The chlorinated derivatives were easily separated by column chromatography on silica gel to give 2-H(2) in good yields. This method for the chlorination of porphyrin using NCS is mild, safe, and economic compared with the established procedure for the meso-chlorination of porphyrins. We also discovered the unexpected meso-chlorination of the porphyrin with dichlorodicyanobenzoquinone (DDQ) by single-electron transfer. Cl(n)TBCODPs 2 were converted into tetrabenzoporphyrins (Cl(n)TBPs) 3 in 100% yields by retro-Diels-Alder reaction. The derived compounds were characterized by NMR spectroscopy, UV/Vis spectrophotometry, cyclic voltammetry (CV), X-ray crystallography, and organic field-effect transistor (OFET) characteristics. The introduction of chlorine at the meso positions of the TBPs drastically changed their electronic and structural properties. The maxima of protonated Cl(4)TBP-H(2) (3d-H(2i) lambda(max) = 494, 649, and 707 nm) were redshifted by around 50-65 nm relative to those of protonated TBP-H(2) (lambda(max) = 431, 605, and 660 nm). The two Q-band maxima of the Cl(4)TBP dication are similar to those of a tetraacenaphthoporphyrin dication (lambda(max) = 525, 646, and 702 nm), which has one of the most redshifted Q-bands. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
  • Tetsuo Okujima, Akihiro Mifuji, Jun Nakamura, Hiroko Yamada, Hidemitsu Uno, Noboru Ono
    ORGANIC LETTERS 11 (18) 4088 - 4091 1523-7060 2009/09 Scientific journal 
    Synthesis of [Ru(phenP)(3)](PF(6))(2), where phenP = phenanthrolinoporphyrin, has been achieved by the reaction of phenanthrolinoporphyrins with RuCl(3) for the first time. The phenP reacted with Ru(II) to form RuL(2)(phenP)(2+) complexes (L = 2,2'-bipyridine or 1,10-phenanthroline), which were converted Into the dyads Ru-phenP(Zn) on treatment with zinc acetate.
  • Akane Masumoto, Yuko Yamashita, Shintetsu Go, Toshihiro Kikuchi, Hiroko Yamada, Tetsuo Okujima, Noboru Ono, Hidemitsu Uno
    JAPANESE JOURNAL OF APPLIED PHYSICS 48 (5) 0515051 - 0515055 0021-4922 2009/05 Scientific journal 
    Organic thin-film transistors were successfully fabricated by the spin-coating method using a photo-precursor of pentacene, 6,13-dihydro-6,13-ethanopentacene-15,16-dione. After spin coating the soluble precursor, irradiation with visible light gave a pentacene film. A good mobility of 0.34 cm(2) V(-1) s(-1) and a high on/off ratio of 2.0 x 10(6) were achieved by treatment of the insulator surface with methyl silsesquioxane and by deposition of pentacene from the precursor with visible light irradiation (>300 nm) and mild heat treatment (110-120 degrees C). In this case, small grains of pentacene crystals existed in the loosely ordered pentacene mesophase, in which pentacene molecules aligned vertically. Not only the grains of pentacene crystals but also the loosely packed pentacene phase played an important role in the field-effect transistor (FET) performance. (C) 2009 The Japan Society of Applied Physics
  • Taiji Akiyama, Hiroki Uoyama, Tetsuo Okujima, Hiroko Yamada, Noboru Ono, Hidemitsu Uno
    TETRAHEDRON 65 (22) 4345 - 4350 0040-4020 2009/05 Scientific journal 
    Nitration of 4,7-ethanoisoindoles gave 1-nitro derivatives in moderate yields. Reduction of a nitro to amino group was successfully performed by sodium hydrosulfite in the case of ethyl 3-nitro-4,7-ethanoisoindole-1-carboxylate. The amino derivative was converted to benzylidenaminoisoindoles based on the retro Diels-Alder reaction. Their UV-vis spectra showed strong absorptions at 500-700 nm. (C) 2009 Elsevier Ltd. All rights reserved.
  • Momoko Saeki, Yuri Hagimoto, Hidemitsu Uno, Masami Kawase
    HETEROCYCLES 79 821 - 830 0385-5414 2009/04 Scientific journal 
    A novel transformation of N-acylprolines (1) to enol esters (2) was realized by utilizing chlorodifluoroacetic or trifluoroacetic anhydrides in the presence of inorganic bases, in which probable intermediates were mesoionic 1,3-oxazolium-5-olates. The structure of the enol ester (2a) was determined by single crystal X-ray analysis.
  • Hidemitsu Uno, Masakazu Hashimoto, Akiko Fujimoto
    HETEROCYCLES 77 (2) 887 - 898 0385-5414 2009/02 Scientific journal 
    Various metalloporphyrins bearing a dihydroethanoisoindole unit were prepared by the inverse-type [3+1] porphyrin synthesis of a bicyclo[2.2.2]octadiene[BCOD]-connected dipyrrole with tetrahydrotripyrrin-dicarbaldehyde followed by metallation. Another [3+1] porphyrin synthesis of the pyrrole-connected porphyrins followed by the second metallation afforded BCOD-connected diporphyrins with different metals. Thermal conversion of the BCOD skeleton into benzene moiety gave pi-system-fused diporphyrin with the different metals in a highly pure form.
  • Hiroki Uoyama, Takahiro Takiue, Kazuyuki Tominaga, Noboru Ono, Hidemitsu Uno
    JOURNAL OF PORPHYRINS AND PHTHALOCYANINES 13 (1) 122 - 135 1088-4246 2009/01 Scientific journal 
    Bicyclo[2.2.2]octadiene (BCOD)-fused porphyrins with no other substituents were prepared by [2 + 2] and [3 + 1] porphyrin syntheses front ethanodihydroisoindole derivatives in fairly good yields. Thermal retro-Diels-Alder reactions of BCOD-fused porphyrins gave the corresponding benzoporphyrins with no substituents in quantitative yields. Their UV-vis spectra and crystal structures were carefully examined in terms of pi-system expansion of the porphyrin ring current. In the cases of monobenzo- and adj-dibenzo-porphyrins, a single Soret band in their UV-vis spectra and no bond alteration in the benzene ring of their crystal structures were observed, while the split Soret bands and the obvious bond alteration in their benzene rings were recorded in the case of opp-dibenzoporphyrin.
  • Yong-Shu Xie, Keisuke Yamaguchi, Motoki Toganoh, Hidemitsu Uno, Masaaki Suzuki, Shigeki Mori, Shohei Saito, Atsuhiro Suka, Hiroyuki Furuta
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 48 (30) 5496 - 5499 1433-7851 2009 Scientific journal 
    Getting in shape: Meso-pentafluorophenyl triply N-confused hexaphyrins have been synthesized in the free-base and oxidized forms and shown to have a triangular shape and efficient emission in the NIR region (see picture). The triangular shape is achieved by the presence of alternating confused and normal pyrrole rings. DFT calculations show that the triangular shape is more stable than a rectangular form. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
  • Dong-Hoon Won, Motoki Toganoh, Hidemitsu Uno, Hiroyuki Furuta
    DALTON TRANSACTIONS (31) 6151 - 6158 1477-9226 2009 Scientific journal 
    Pt(II) complex of meso-tetrakis(pentafluorophenyl) N-confused porphyrin (1-Pt) efficiently binds Cl-, Br-, and I- anions at the peripheral N-H, while deprotonation proceeds with F-, H2PO4-, and OH- in CH2Cl2 solution; neutral and anionic structures of 1-Pt were characterized by single crystal X-ray diffraction analysis.
  • Akio Kamimura, Ayako Kadowaki, Takayuki Yoshida, Ryota Takeuchi, Hidemitsu Uno
    CHEMISTRY-A EUROPEAN JOURNAL 15 (40) 10330 - 10334 0947-6539 2009 Scientific journal 
    A novel one-step radical-ionic cyclopropanation was carried out to prepare aza- or oxabicyclo[3.1.0]hexane from β-nitroamides or β-nitroethers in a stereoselective manner (see scheme). The present procedure involves a higher-order domino process that includes one-electron oxidationradical cyclization-intramolecular SN2 reaction. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
  • Akio Kamimura, Takayuki Yoshida, Hidemitsu Uno
    TETRAHEDRON 64 (49) 11081 - 11085 0040-4020 2008/12 Scientific journal 
    A concise and stereoselective formation of azepines is achieved through the Conjugate addition of formamides to nitroalkenes and the subsequent intramolecular nitrile oxide cycloaddition (INOC) reaction. High cis-selectivity was observed. The one-pot modification of the two reactions provides direct preparation of azepines from nitroalkenes and formamides in moderate yields. The formyl group was readily removed by an acidic treatment without significant epimerization. (C) 2008 Elsevier Ltd. All rights reserved.
  • Makoto Kuramoto, Norimichi Miyake, Yoshihisa Ishimaru, Noboru Ono, Hidemitsu Uno
    ORGANIC LETTERS 10 (23) 5465 - 5468 1523-7060 2008/12 Scientific journal 
    The novel alkaloids cylindradines A and B were isolated from Axinella cylindratus, and their structures were elucidated by spectroscopic analyses. Stereochemistries of these compounds were determined by X-ray analysis. Cylindradines showed moderate inhibitory activity against the murine leukemia cell line P388.
  • Hiroko Yamada, Kayo Kushibe, Satoshi Mitsuogi, Tetsuo Okujima, Hidemitsu Uno, Noboru Ono
    TETRAHEDRON LETTERS 49 (32) 4731 - 4733 0040-4039 2008/08 Scientific journal 
    One of 5-alkenyl-15-alkynyl-porphyrin and 5,15-dialkynyl-porphyrin was prepared selectively by 2+2 acid-catalyzed condensation of bicyclo[2.2.2]octadiene-fused dipyrrylmethane and TMS propynal in the presence of BF(3) OEt(2) only by the choice of the solvent. The alkenyl group was expected to be obtained by a protonation followed by intramolecular 1,2-hydride transfer from methine position of porphyrinogen. (C) 2008 Elsevier Ltd. All rights reserved.
  • Sumanta Bhattacharya, Masakazu Hashimoto, Akiko Fujimoto, Takahide Kimura, Hidemitsu Uno, Naoki Komatsu
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 70 (2) 416 - 424 1386-1425 2008/07 Scientific journal 
    The present paper highlights the photophysical aspects of the topologically new Ni(II)-diporphyrin (Ni-2-1)/fullerene host-guest ensembles. Both absorption and fluorescence studies reveal that Ni-2-1 undergoes efficient complexation with both C-60 and C-70 in toluene medium. In the fluorescence study, remarkable enhancement of the fluorescence intensity of Ni-2-1 was observed by the addition of C-60, while normal quenching of fluorescence occurred in case of C-70. From the fluorescence and UV-vis studies, the binding constants of Ni-2-1 with C-60 and C-70 were determined to be similar to 1.7 x 10(4) and similar to 2.7 x 10(4) dm(3) mol(-1), respectively. Ab initio theoretical calculations reveal that C-70/Ni-2-1 complex favor end-on orientation of C-70 rather than side-on approach. (C) 2007 Elsevier B.V. All rights reserved.
  • Hiroko Yamada, Daiki Kuzuhara, Tetsuro Takahashi, Yusuke Shimizu, Keisuke Uota, Tetsuo Okujima, Hidemitsu Uno, Noboru Ono
    ORGANIC LETTERS 10 (14) 2947 - 2950 1523-7060 2008/07 Scientific journal 
    Linearly pi-expanded novel tetraanthroporphyrins with and without aromatic rings at the meso-positions were prepared quantitatively for the first time from the corresponding precursors by a retro-Diels-Alder reaction.
  • Tomohiro Taniguchi, Taka-aki Fukuba, Shuhei Nakatsuka, Shuichi Hayase, Motoi Kawatsura, Hidemitsu Uno, Toshiyuki Itoh
    JOURNAL OF ORGANIC CHEMISTRY 73 (10) 3875 - 3884 0022-3263 2008/05 Scientific journal 
    Candida antarctica lipase B (CAL-B) is one the most frequently used enzymes in organic synthesis for the preparation of optically active alcohols. However, it has not been used for the optical resolution of (+/-)-2,2'-binaphthol. We established an efficient linker-oriented design of 2,2'-binaphthol derivatives that is appropriate for optical resolution using CAL-B-catalyzed hydrolysis reaction. Methyl 4-(1-(6-bromo-2-methoxymethoxynaphthalen-1-yl)-6-bromonaphthalen-2-yloxy)butanoate was hydrolyzed by CAL-B to afford a corresponding acid with excellent enantioselectivity (E > 200). Two types of optically active binaphthol derivatives, 1-(2-hydroxy-6-(naphthalen-1-yl)naphthalen-1-yl)-6-(naphthalen-1-yl)naphthalen-2-ol and 6-butyl-1-(6-butyl-2-hydroxynaphthalen-1-yl)naphthalen-2-ol, were prepared by this chemo-enzymatic reaction protocol and were used as chiral templates for symmetric reactions.
  • Yoshihiro Matano, Kazuaki Matsumoto, Yoshihide Nakao, Hidernitsu Uno, Shigeyoshi Sakaki, Hiroshi Imahori
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 130 (14) 4588 - + 0002-7863 2008/04 Scientific journal 
    meso-Diphenylphosphanylporphyrins were successfully prepared via Pd-catalyzed C-P cross-coupling reaction of the corresponding meso-iodoporphyrins with diphenylphosphane. The meso-phosphanylporphyrins underwent regioselective metalation at the beta carbon to produce novel classes of porphyrin dimers linked by peripherally fused phosphametallacycles. A Pd-mononucler complex was structurally characterized by X-ray crystallography, which revealed a flat structure of the Pd-linked porphyrin pi systems. Both experimental and theoretical results demonstrate that the orbital interaction between the pyrrolic p pi orbitals and the metal d pi orbital affects optical and electrochemical properties of the metal-linked coplanar porphyrin dimers.
  • Tetsuo Okujima, Yusuke Hashimoto, Guangnan Jin, Hiroko Yamada, Hidemitsu Uno, Noboru Ono
    TETRAHEDRON 64 (10) 2405 - 2411 0040-4020 2008/03 Scientific journal 
    This paper describes the preparation of dimethylbicyclo[2.2.2]octadiene-fused porphyrins as extremely soluble precursors of tetrabenzoporphyrins and thermal conversion of the precursors to tetrabenzoporphyrins. (C) 2008 Elsevier Ltd. All rights reserved.
  • Yoshihiro Matano, Kazuaki Matsumoto, Yoshihide Nakao, Hidemitsu Uno, Shigeyoshi Sakaki, Hiroshi Imahori
    Journal of the American Chemical Society American Chemical Society 130 (14) 4588 - 4589 1520-5126 2008 [Peer-reviewed]
     Scientific journal
  • Hidernitsu Uno, Yusuke Shimizu, Hiroki Uoyama, Yousuke Tanaka, Tetsuo Okujima, Noboru Ono
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2008 (1) 87 - 98 1434-193X 2008/01 Scientific journal 
    Multistep thermal fragmentation of quadruply bicyclo[2.2.2]octadiene-fused porphyrins giving tetrabenzoporphyrins was examined in detail. After the first extrusion of an ethylene molecule from the porphyrin derivative, the opposite bicyclo[2.2.2]octadiene moiety preferentially underwent the second retro-Diels-Alder reaction to give an opp-dibenzoporphyrin derivative rather than an adj-dibenzoporphyrin derivative. These two benzoporphyrin derivatives then decomposed to give a tribenzoporphyrin derivative in similar rates. The temperature regions of these fragmentations could not be distinguished by thermogravimetric analysis. In contrast, the third and the fourth fragmentations obviously occurred stepwise. There was a temperature region where the tribenzoporphyrin derivative preferentially existed. In the case of the 21,23-dithiaporphyrin derivative, opp-21,23-dithiadibenzoporphyrin, possessing benzo moieties fused at the pyrrole parts of the core-modified porphyrin chromophore was predominantly formed during the fragmentation. In the case of the 21-thiaporphyrin derivative, an ethylene molecule was extruded selectively from the bicyclo[2.2.2]octadiene moiety adjacent to the thiophene part to give 21-thiabenzo[q]phyrin and then 21-thiabenzo[g,q]porphyrin derivatives. In these cases, the last ethylene extrusion also occurred very slowly. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008).
  • John Mack, Masaru Bunya, Yusuke Shimizu, Hiroki Uoyama, Naoki Komobuchi, Tetsuo Okujima, Hidemitsu Uno, Satoshi Ito, Martin J. Stillman, Noboru Ono, Nagao Kobayashi
    CHEMISTRY-A EUROPEAN JOURNAL 14 (16) 5001 - 5020 0947-6539 2008 Scientific journal 
    The optical spectra of a series of core-modified tetrabenzoporphyrins were analyzed to determine the effects of core modification, ligand folding, and partial benzo substitution at the ligand periphery on the electronic structure by using magnetic circular dichroism (MCD) and NMR spectroscopy, X-ray crystallography, cyclic and differential pulse voltammetry, and TD-DFT calculations. Planar 21-carba-, 21-thia-, 21,23-dithia-, and 21-oxa-23thiatetrabenzo[b,g,l,q]porphyrins reported previously were studied together with the previously unreported 21-oxa- and 21-carba-23-thiatetrabenzo[b,g,l,q]porphyrins. The optical properties of these compounds are compared to those of tetrabenzo[b,g,l,q]-, 5,.10,15,20-tetraphenyl-, 5,10,15,20-tetraphenyltetrabenzo[b,g,l,q]-21-thia-, 5,10,15,20-tetraphenyltetrabenzodithia-, 5,10,15,20-tetraphenyldibenzo[g,q]21,23-dithia-, 5,10,15,20-tetraphenyldibenzo[b,t]-21,23-ditliia-, 5,10,15,20tetraphenyltribenzo[g,q]-1-21-thia-, and 5,10,15,20-tetraphenylbenzo[b]-21-thia- porphyrins. Michl's perimeter model and Gouterman's four-orbital model are used to conceptualize the results and to account for red shifts commonly observed in the spectral bands of nonplanar porphyrinoids.
  • Dong-Hoon Won, Motoki Toganoh, Yosuke Terada, Susumu Fukatsu, Hidemitsu Uno, Hiroyuki Furuta
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 47 (29) 5438 - 5441 1433-7851 2008 Scientific journal 
    Light from confusion: A set of doubly N-confused calix[6]phyrins bearing two coordination sites (NNNC,NNNC or NNNN,NNCC) were synthesized. Their bis-PtII complexes exhibit near-infrared emission around 1000 nm, which could make these compounds ideal for biological applications. (Graph Presented). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
  • Atsuko Hirao, Taiji Akiyama, Tetsuo Okujima, Hiroko Yamada, Hidemitsu Uno, Yoshimasa Sakai, Shinji Aramaki, Noboru Ono
    CHEMICAL COMMUNICATIONS (39) 4714 - 4716 1359-7345 2008 Scientific journal 
    Soluble precursors of 2,3-naphthalocyanine (Nc) and phthalocyanine (Pc) were prepared and were converted into insoluble semiconducting thin films of Pc and Nc by heating after fabrication via spin-coating.
  • Motoki Toganoh, Tomoyuki Kimura, Hidemitsu Uno, Hiroyuki Furuta
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 47 (46) 8913 - 8916 1433-7851 2008 Scientific journal 
    (Figure Presented) Are you N-fused? Doubly N-fused porphyrin (see picture; Br red, F green, N blue) exhibits exceptionally long-wavelength absorption for an 18π aromatic system (in excess of 1600 nm). The HOMO-LUMO energy gap of doubly N-fused porphyrin is extremely small for an [18]annulenic compound and results from endocyclic extension of the porphyrin π system. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
  • Hiroki Uoyama, Keisuke Nakamura, Marie Tukiji, Mina Furukawa, Hidemitsu Uno
    HETEROCYCLES 73 (1) 673 - + 0385-5414 2007/12 Scientific journal 
    The Diels-Alder reactions of tetrafluorobenzo[c]thiophene with electron-deficient olefins such p-benzoquinone and bis(phenylsulfonyl)ethylene gave adducts in moderate yields, while no product was obtained in the reaction with butyl vinyl ether. The Vilsmeier reaction gave tetrafluorobenzo[c]thiophene-1-carbaldehyde in good yield. The aldehyde was converted to tetrafluorothiabenzoporphyrin.
  • Shin-ichi Nagaoka, Akiko Fujii, Megumi Hino, Mai Takemoto, Misaki Yasuda, Mariko Mishima, Keishi Ohara, Akane Masumoto, Hidemitsu Uno, Umpei Nagashima
    JOURNAL OF PHYSICAL CHEMISTRY B 111 (45) 13116 - 13123 1520-6106 2007/11 Scientific journal 
    The UV protection and singlet oxygen quenching of aloesaponarin I have been studied by means of laser spectroscopy. The excited-state intramolecular proton transfer that provides the UV protection takes place along only one of the molecule's two intramolecular hydrogen bonds, and this can be understood by considering the nodal pattern of the wave function. The functional groups participating in the excited-state intramolecular proton transfer also play important roles in the singlet oxygen quenching. Aloesaponarin I has a quenching rate constant larger than that of vitamin E and has a long duration of action due to its resistance to UV degradation and chemical attacks by singlet oxygen and free radicals.
  • Akio Kamimura, Yoshiaki Nagata, Ayako Kadowaki, Kosuke Uchida, Hidemitsu Uno
    TETRAHEDRON 63 (48) 11856 - 11861 0040-4020 2007/11 Scientific journal 
    Optically active 5-substituted pyrrolidin-2-ones underwent conjugate addition to nitroalkenes to give the corresponding adducts in a diastereoselective manner. The presence of 18-crown-6 was crucial to achieve good stereoselective addition. Addition of 6-substituted piperidin-2-ones also gave the corresponding adduct in a stereoselective manner. The adduct was readily converted into a bicyclic lactam through intramolecular nitroaldol reaction, and the formal synthesis of indolizidine 167B was achieved. (c) 2007 Elsevier Ltd. All rights reserved.
  • Toshiyuki Itoh, Manabu Kanbara, Masakazu Ohashi, Shuichi Hayase, Motoi Kawatsura, Takashi Kato, Kazutoshi Miyazawa, Yumiko Takagi, Hidemitsu Uno
    JOURNAL OF FLUORINE CHEMISTRY 128 (10) 1112 - 1120 0022-1139 2007/10 Scientific journal 
    The synthesis of a novel chiral gem-difluorocyclopropane building block has been accomplished using chemo-enzymatic reaction protocol; the prochiral diol of 1,4-bis(2,2-difluoro-3-(hydroxymethyl)cyclopropyl)benzene (5) was converted to the corresponding chiral diacetate by Pseudomonas lipase (lipase SL-25, Meito)-catalyzed transesterification with vinyl acetate as acyl donor with > 99% enantiomeric excess. Various types of diesters or dialkyl ether were prepared from the diol and their helical twisting power (HTP) was evaluated by addition of 1.0 wt% to a non-chiral nematic liquid crystal host; the HTP was significantly dependent on the structure of ester or ether moieties and diester of diol 5 with isopropylfumalic acid showed the largest HTP. (C) 2007 Elsevier B.V. All rights reserved.
  • Hidemitsu Uno, Go Masuda, Marie Tukiji, Yulko Nishioka, Toshiya Lida
    TETRAHEDRON LETTERS 48 (42) 7512 - 7515 0040-4039 2007/10 Scientific journal 
    4,5,6,7-Tetrafluoroisoindole and their related compounds were prepared directly from the corresponding phthalonitriles by reduction of a hydride reagent such as DIBAL or catalytic hydrogenation in the presence of an acid. 4,5,6,7-Tetrafluoroisoindole was converted to fluorinated benzoporphyrins. (C) 2007 Elsevier Ltd. All rights reserved.
  • Hidemitsu Uno, Yuri Sahara, Takahiro Takiue
    TETRAHEDRON LETTERS 48 (44) 7825 - 7828 0040-4039 2007/10 Scientific journal 
    Porphyrin synthesis using 4,7-etheno-4,7-dihydro-2H-isoindole and tripyrranedicarbaldehyde gave a porphyrin derivative bearing no bicyclo[2.2.2]octatriene moiety as well as the targeted bicyclo[2.2.2 ]octatriene-fused porphyrin. (C) 2007 Elsevier Ltd. All rights reserved.
  • Masahiro Sakanaka, Pengxiang Zhu, Bo Zhang, Tong-Chun Wen, Fang Cao, Yong-Jie Ma, Keiichi Samukawa, Noriaki Mitsuda, Junya Tanaka, Makoto Kuramoto, Hidemitsu Uno, Ryuji Hatai
    JOURNAL OF NEUROTRAUMA 24 (6) 1037 - 1054 0897-7151 2007/06 Scientific journal 
    Red ginseng root (Panax Ginseng CA Meyer) has been used clinically by many Asian people for thousands of years without any detrimental effects. One of the major components of Red ginseng root is ginsenoside Rb-1 (gRb1). Previously, we showed that intravenous infusion of gRb1 ameliorated ischemic brain damage through upregulation of an anti-apoptotic factor, BCI-X-L and that topical application of gRb1 to burn wound lesion facilitated wound healing through upregulation of vascular endothelial growth factor (VEGF). In the present study, we produced dihydroginsenoside Rb1 (dgRb1), a stable chemical derivative of gRb1, and showed that intravenous infusion of dgRb1 improved spinal cord injury (SCI) as well as ischemic brain damage. As we expected, the effective dose of dgRb1 was ten times lower than that of gRb1. Intravenous infusion of dgRb1 at this effective dose did not affect brain temperature, blood pressure or cerebral blood flow, suggesting that dgRb1 rescued damaged neurons without affecting systemic parameters. In subsequent in vitro studies that focused on dgRb1-induced expression of gene products responsible for neuronal death or survival, we showed that dgRb1 could upregulate the expression of not only BCI-XL, but also a potent angiogenic and neurotrophic factor, VEGF. We also showed that dgRb1-induced expression of bcl-X-L and VEGF mRNA was HRE (hypoxia response element) and STRE (signal transducers and activators of transcription 5 (Stat5) response element) dependent, respectively.
  • Hiroki Uoyama, Noboru Ono, Hidemitsu Uno
    HETEROCYCLES 72 363 - 372 0385-5414 2007/04 Scientific journal 
    Nitration of biphenylene with bismuth subnitrate and thionyl chloride give a mixture of 2-nitrobiphenylene, 2-chloro-6-nitrobiphenylene, and 5-chloro-10-nitrobenzocyclooctene. Reactions of 2-nitrobiphenylene and 5-chloro-10-nitrobenzocyclooctene with ethyl isocyanoacetate in the presence of t-BuOK gave the corresponding pyrimidine N-oxide and pyrrole, respectively.
  • Akio Kamimura, Hidenori Okawa, Yuki Morisaki, Shingo Ishikawa, Hidemitsu Uno
    JOURNAL OF ORGANIC CHEMISTRY 72 (9) 3569 - 3572 0022-3263 2007/04 [Peer-reviewed]
     Scientific journal 
    Optically active N-sulfinimines underwent stereoselective Michael/nucleophilic addition domino reaction triggered by magnesium thiolate to give alpha-phenylthiomethyl-beta-(N-sulfinylamino) esters in high diastereomeric excess. The adducts were readily converted into optically active alpha-methylene-beta-(N-sulfinylamino)esters so that this reaction provides a useful asymmetric aza-Baylis-Hillman-equivalent method.
  • Ayako Kadowaki, Yoshiaki Nagata, Hidemitsu Uno, Akio Kamimura
    TETRAHEDRON LETTERS 48 (10) 1823 - 1825 0040-4039 2007/03 Scientific journal 
    The stereoselective intramolecular nitrile oxide cycloaddition (INOC) reaction was achieved from N-formyl-beta-nitroamides, which were prepared through the Michael addition of allylic formamides to nitroalkenes, and cis-pyrroroisoxazoles and trans-piperidinoisoxazoles were obtained in a stereoselective manner. (c) 2007 Elsevier Ltd. All rights reserved.
  • Motoi Kawatsura, Fumio Ata, Shohei Wada, Shuichi Hayase, Hidemitsu Uno, Toshiyuki Itoh
    CHEMICAL COMMUNICATIONS (3) 298 - 300 1359-7345 2007 Scientific journal 
    The regioselectivity in the ruthenium-catalysed allylic alkylation of mono substituted allyl acetates with the malonate anion was highly controlled by Ru-3(CO)(12) with 2-(diphenylphosphino)benzoic acid, and the linear-type alkylated product was obtained.
  • Sumanta Bhattacharya, Kazuyuki Tominaga, Takahide Kimura, Hidemitsu Uno, Naoki Komatsu
    CHEMICAL PHYSICS LETTERS 433 (4-6) 395 - 402 0009-2614 2007/01 Scientific journal 
    The present Letter introduces a new type of metalloporphyrin dimer, 1, to examine its optical absorption and luminescence in complexation with C-60 and C-70 in toluene medium. Large binding constants (K) in the magnitude of similar to 3 x 10(4) and similar to 2 x 10(5) dm(3) Mol(-1) were obtained for the 1: 1 complexes of 1 with C-60 and C-70, respectively. Values of K suggest that 1 serves as an effective and selective tweezers to capture C-70 in preference to C-60. Molecular mechanics and semi-empirical PM3 calculations extend a good support in interpreting the stabilization energies and electronic structures for the C-60 and C-70 complexes of 1. (c) 2006 Elsevier B.V. All rights reserved.
  • Tatsuki Morimoto, Hidemitsu Uno, Hiroyuki Furuta
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 46 (20) 3672 - 3675 1433-7851 2007 Scientific journal 
    Ring a ring of benzenes: An unsubstituted N-confused metalloporphyrin forms both C3- and C1-symmetric trimers in solution, whereas its monophenyl-substituted analogue forms exclusively C3-symmetric trimers (see picture) owing to significant stabilizing noncovalent interactions between the three phenyl groups, as evaluated both experimentally and theoretically. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
  • Hidemitsu Uno, Ken-ichi Nakamoto, Kenji Kuroki, Akiko Fujimoto, Noboru Ono
    CHEMISTRY-A EUROPEAN JOURNAL 13 (20) 5773 - 5784 0947-6539 2007 Scientific journal 
    Bicyclo[2.2.2]octadiene-connected pyrrolo-porphyrins have been prepared by an inverse-type [3+1] porphyrin synthesis of a bicyclo[2.2.2]octadiene-fused dipyrrole with a tripyrrane dicarbaldehyde. Another [3+1] porphyrin synthesis of pyrrole-connected porphyrins with the same or other tripyrrane dicarbalde- hydes gave bicyclo[2.2.2]octadiene-bridged diporphyrins, the central metals and/or peripheral substituents of which were different. Thermal decomposition of the, bicyclo[2.2.2]octadiene skeleton to a benzene moiety gave pi-system-fused porphyrin dimers in a highly pure form.
  • Taiji Akiyama, Atsuko Hirao, Tetsuo Okujima, Hiroko Yamada, Hidemitsu Uno, Noboru Ono
    HETEROCYCLES 74 835 - 842 0385-5414 2007 Scientific journal 
    Mg complex of phthalocyanine fused with bicyclo[2.2.2]octadiene (BCOD) units is prepared by the reaction of BCOD-fused phthalonitrile with Mg(OPr)(2) in PrOH at 100 degrees C overnight in 42% yield. Subsequent heating the product at 250 degrees C results in clean formation naphthalocyanine via the retro Diels-Alder reaction. An attempt to the synthesis of BCOD-fused tetraazaporphyrin by the similar cyclization of the Diels-Alder adduct of dicyanoacetylene with 1,3-cyclohexadiene was unsuccessful.
  • Tetsuo Okujima, Guangnan Jin, Yusuke Hashimoto, Hiroko Yamada, Hidemitsu Uno, Noboru Ono
    HETEROCYCLES 70 619 - + 0385-5414 2006/12 Scientific journal 
    Diels-Alder reaction of ethynyl p-tolyl sulfone with 1,3-dienes gave the corresponding tosyl-1,4-cyclohexadienes. The resulting adducts could be converted into 4,7-dihydro-2H-isoindole derivatives including bicyclo[2.2.2]ocatadiene(BCOD)-fused pyrrole as an isoindole equivalent.
  • Hiroko Yamada, Emi Kawamura, Sadaaki Sakamoto, Yuko Yamashita, Tetsuo Okujima, Hidemitsu Uno, Noboru Ono
    TETRAHEDRON LETTERS 47 (42) 7501 - 7504 0040-4039 2006/10 Scientific journal 
    A diketone precursor of air-stable bis-2-thienyl-2,6-anthracene was prepared and quantitatively converted to the target acene by photoirradiation of the n-pi* absorption both in solution and as a film, in air. (c) 2006 Elsevier Ltd. All rights reserved.
  • A Kamimura, A Kadowaki, Y Nagata, H Uno
    TETRAHEDRON LETTERS 47 (15) 2471 - 2473 0040-4039 2006/04 Scientific journal 
    Secondary acyclic formamide serves as an efficient nucleophile to nitroalkenes to give corresponding Michael adducts in good yields. The nitro group in the adducts was useful for further heterocyclic synthesis. (c) 2006 Elsevier Ltd. All rights reserved.
  • T Okujima, N Komobuchi, H Uno, N Ono
    HETEROCYCLES 67 (1) 255 - 267 0385-5414 2006/01 Scientific journal 
    Benzoporphyrins fused with acenaphthylene or fluoranthene (3) and (4) were prepared by the condensation of bicyclo[2.2.2]octadiene(BCOD)-fused tripyrrane (5) with appropriate pyrrole dialdehydes (13) or (14) and the subsequent retro Diels-Alder reaction. The absorptions of these new porphyrins were very intense at both Soret and Q bands, which might be useful as organic dyes for solar cells.
  • H Yamada, K Kushibe, T Okujima, H Uno, N Ono
    CHEMICAL COMMUNICATIONS (4) 383 - 385 1359-7345 2006/01 Scientific journal 
    5-Alkenyl-15-alkynylporphyrins have been obtained unexpectedly by [2 + 2] acid-catalyzed condensation of dipyrrylmethane and TMS propynal in addition to 5,15-dialkynylporphyrin, and the unsymmetrical porphyrin can be converted to a butadiyne-linked dimer by selective desilylation of the alkynyl TMS.
  • Tetsuo Okujima, Makoto Kikuchi, Hiroko Yamada, Hidemitsu Uno, Noboru Ono
    JOURNAL OF PORPHYRINS AND PHTHALOCYANINES 10 (9-10) 1197 - 1201 1088-4246 2006 Scientific journal 
    Soluble tetra(pyrazino)tetraazaporphyrin was synthesized by the reaction of bicyclo[2.2.2]octadiene-fused dicyanopyrazine. The retro Diels-Alder reaction of the soluble tetra(pyrazino)tetraazaporphyrin gave a tetra(quinoxalino)tetraazaporphyrin in quantitative yield. Copyright (c) 2006 Society of Porphyrins & Phthalocyanines.
  • H Yamada, Y Yamashita, M Kikuchi, H Watanabe, T Okujima, H Uno, T Ogawa, K Ohara, N Ono
    CHEMISTRY-A EUROPEAN JOURNAL 11 (21) 6212 - 6220 0947-6539 2005/10 Scientific journal 
    A novel alpha-diketone precursor of pentacene, 6,13-dihydro-6,13-ethanopentacene-15,16-dione, was prepared and converted successfully to pentacene in 74% yield by photolysis of the precursor in toluene: Irradiation of the diketone solution in toluene with light of 460 nm under an Ar atmosphere caused the solution to change from yellow to fluorescent orange-pink within a few minutes, after which, purple precipitates appeared. After 35 min, the solution changed to colorless and the purple precipitates were filtered to give pentacene in 74% yield. By contrast, in the presence of oxygen, the color of the solution changed from yellow to pale yellow., and only 6,13-endoperoxide of pentacene was quantitatively obtained. The rate of the reaction upon photolysis was measured by observing the decay of n-pi* absorption of the precursor at 460 nm, and was found to be similar in both the presence and absence of oxygen. Therefore, the photoreaction of the alpha-diketone precursor seemed to occur via the singlet excited state. Because the T-T absorption of pentacene was observed upon photolysis of the precursor in the nanosecond transient absorption measurement under an Ar atmosphere, the excited triplet state of the pentacene generated singlet oxygen by sensitization, and it reacted with the ground-state pentacene to give the 6,13-endoperoxide. The alpha-diketone deposited on glass was also converted successfully to pentacene film by photoirradiation. In addition, diketone precursors of a mixture of 2,8- and 2,9-di-bromopentacene and 2,6-trianthrylene were also prepared and their photoconversion was performed.
  • XJ Lin, Z Shen, YZ Li, H Uno, Y Song, HJ Xu, XZ You
    JOURNAL OF COORDINATION CHEMISTRY 58 (13) 1139 - 1144 0095-8972 2005/09 Scientific journal 
    A new binuclear Cu(II) complex: [Cu-2(phen)(2)(4,4'-dpy)(3)(OH)(2)] center dot 2NO(3) center dot 5.5H(2)O (phen = 1,10-phenanthroline and 4,4'-dpy = 4,4'-dipyridine) 1 has been prepared and determined by single X-ray diffraction. The two Cu2+ ions are bridged by a 4,4'-dpy ligand. The intramolecular coupling between the two Cu-II (S = 1/2) ions was found to be weakly antiferromagnetic (J = - 0.38 cm(-1)).
  • H Uno, S Murakami, A Fujimoto, Y Yamaoka
    TETRAHEDRON LETTERS 46 (23) 3997 - 4000 0040-4039 2005/06 Scientific journal 
    The first total synthesis of bhimamycin B, a novel member of naphtho[2,3-c]furan quinone antibiotics, was achieved by oxidative skeletal rearrangement of 4-acetylnaphtho[1,2-b]furan-5-ol. (c) 2005 Elsevier Ltd. All rights reserved.
  • K Ohara, W Mizukami, A Tokunaga, S Nagaoka, H Uno, K Mukai
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 78 (4) 615 - 621 0009-2673 2005/04 Scientific journal 
    A kinetic Study was performed for the free-radical scavenging actions of curcumin and half-curcumin, which has a half-structure of curcumin, in order to clarify the mechanism of free-radical-scavenging in curcumin. The second-order rate constants for radical-scavenging reactions of curcumin and half-curcumin were measured by a stopped-flow spectrophotometer in several organic solvents (methanol, ethanol, acetonitrile, chloroform, and benzene) and in aqueous Triton X-100 (5.0 wt %) micelle solutions at various pH. The difference in the rate constant and solvent dependence between curcumin and half-curcumin suggests that the enol structure with the intramolecular hydrogen-bond Of Curcumin strongly enhances the radical-scavenging activity. Furthermore, notable pH dependences were observed for the rate constants of curcumin and half-curcumin in micelle solutions, suggesting that the acid-base dissociation equilibrium of phenol-protons in curcumin and half-curcumin affects their radical-scavenging activities.
  • H Uno, Y Yamashita, M Kikuchi, H Watanabe, H Yamada, T Okujima, T Ogawa, N Ono
    TETRAHEDRON LETTERS 46 (12) 1981 - 1983 0040-4039 2005/03 Scientific journal 
    6,13-Dihydro-6,1 3-ethanopentacene-15,16-dione gave pentacene efficiently both in solid and in solution by irradiation of light. (C) 2005 Elsevier Ltd. All rights reserved.
  • T Murashima, S Tsujimoto, T Yamada, T Miyazawa, H Uno, N Ono, N Sugimoto
    TETRAHEDRON LETTERS 46 (1) 113 - 116 0040-4039 2005/01 Scientific journal 
    Water-soluble bicycloporphyrin and benzoporphyrin having octacarboxyl groups are synthesized from the corresponding octaester porphyrin by simple hydrolyzing and heating procedures. These compounds are characterized by UV-vis, NMR and mass spectroscopies. The benzoporphyrin octacarboxylic acid exhibits extremely high planarity in spite of its poly-substitution. (C) 2004 Elsevier Ltd. All rights reserved.
  • H Uno, H Watanabe, Y Yamashita, N Ono
    ORGANIC & BIOMOLECULAR CHEMISTRY 3 (3) 448 - 453 1477-0520 2005 Scientific journal 
    X-Ray analyses of free base, zinc, and nickel complexes of 2,3; 7,8; 12,13; 17,18-tetrakis(6,13-dihydro-6,13-pentaceno)-21H,23H-porphine revealed that the porphyrin chromophores adopted a heavily-saddled conformation by interlocking of the biconcave porphyrins in the crystals containing halobenzenes as crystalline solvents, while the ring was almost at in the crystals obtained from benzene or from chlorobenzene and isopropanol.
  • Y Inokuma, T Matsunari, N Ono, H Uno, A Osuka
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 44 (12) 1856 - 1860 1433-7851 2005 Scientific journal 
    A retro-Diels-Alder reaction of a β-bicyclo[2.2.2]octadiene-fused precursor yields the doubly N-fused β-benzo[28]-hexaphyrin(1.1.1.1.1.1) shown, which undergoes oxidative rearrangement upon treatment with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) to yield a macrocycle that emits fluorescence in the visible/near-IR region. (Chemical Equation Presented) © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.
  • Y Inokuma, N Ono, H Uno, DY Kim, SB Noh, D Kim, A Osuka
    CHEMICAL COMMUNICATIONS (30) 3782 - 3784 1359-7345 2005 Scientific journal 
    Enlargement of the pi-electronic network of meso-meso, beta-beta, beta-beta triply linked diporphyrin has been exploited by preparing a corresponding dibenzo-fused porphyrin dimer that exhibits a perturbed absorption spectrum and a large two-photon absorption cross section.
  • H Uno, K Moriyama, T Ishikawa, N Ono, H Yahiro
    TETRAHEDRON LETTERS 45 (49) 9083 - 9086 0040-4039 2004/11 Scientific journal 
    2,2'-Bi[-3(2H)-thioplienon]ylidene with two bicyclo[2.2.2]-octadiene moieties was quantitatively converted to thioindigo by the retro-Diels-Alder reaction. The thioindigo solid obtained from the precursor had the P2(1)/c structure which was different from the commercial thioindigo samples (P2(1)/n). (C) 2004 Elsevier Ltd. All rights reserved.
  • Z Shen, H Rohr, K Rurack, H Uno, M Spieles, B Schulz, G Reck, N Ono
    CHEMISTRY-A EUROPEAN JOURNAL 10 (19) 4853 - 4871 0947-6539 2004/10 
    The X-ray crystallographic, optical spectroscopic, and electrochemical properties of a newly synthesized class of boron-diindomethene (BDI) dyes and their tetrahydrobicyclo precursors (bc-BDP) are presented. The BDI chromophore was designed to show intensive absorption and strong fluorescence in an applicationary advantageous spectral range. Its modular architecture permits fusion of a second subunit, for example, a receptor moiety to the dye's core to yield directly linked yet perpendicularly prearranged composite systems. The synthesis was developed to allow facile tuning of the chromophore platform and to thus adjust its redox properties. X-ray analysis revealed a pronounced planarity of the chromophore in the case of the BDIs, which led to a remarkable close packing in the crystal of the simplest derivative. On the other hand, deviation from planarity was found for the diester-substituted bc-BDP benzocrown that exhibits a "butterfly"-like conformation in the crystal. Both families of dyes show charge- or electron-transfer-type fluorescence-quenching characteristics in polar solvents when equipped with a strong donor in the meso-position of the core. These processes can be utilized for signaling purposes if an appropriate receptor is introduced. Further modification of the chromophore can invoke such a guest-responsive intramolecular quenching process, also for receptor groups of low electron density, for example, benzocrowns. In addition to the design of various prototype molecules, a promising fluoroionophore for Na(+) was obtained that absorbs and emits in the 650 nm region and shows a strong fluorescence enhancement upon analyte binding. Furthermore, investigation of the remarkable solvatokinetic fluorescence properties of the "butterfly" -like bc-BDP derivatives suggested that a second intrinsic nonradiative deactivation channel can play a role in the photophysics of boron-dipyrromethene dyes.
  • T Okujima, N Komobuchi, Y Shimizu, H Uno, N Ono
    TETRAHEDRON LETTERS 45 (28) 5461 - 5464 0040-4039 2004/07 Scientific journal 
    A bicyclo[2.2.2]octadiene-fused tripyrrane was synthesized as a first versatile reagent for the preparation of pi-expanded heteroporphyrins. The reaction of the tripyrrane with 1,3-diformylindene and azulene-1,3-dicarbaldehyde afforded the corresponding heteroporphyrins. which were easily converted into tetrabenzocarbaporphyrin and tribenzoazuliporphyrin by retro Diels-Alder reaction. (C) 2004 Elsevier Ltd. All rights reserved.
  • Y Shimizu, Z Shen, T Okujima, H Uno, N Ono
    CHEMICAL COMMUNICATIONS 10 (4) 374 - 375 1359-7345 2004/02 Scientific journal 
    Successful synthesis of a series of highly conjugated porphyrin analogues, including thia-, dithia- and oxathia-tetrabenzoporphyrins, and their optical properties are reported.
  • N Ono, K Kuroki, E Watanabe, N Ochi, H Uno
    HETEROCYCLES 62 365 - 373 0385-5414 2004/01 Scientific journal 
    Sapphyrins fused with mono-bicyclo[2.2.2]octadiene (BCOD) and di-BCOD units are prepared, which are converted into mono- and dibenzosappyrins by heating at 200 degreesC; soret bands are red shifted by 10-20 nm by introduction of fused benzene rings, but Q bands are not much affected in benzosapphyrins.
  • Z Shen, H Uno, Y Shimizu, N Ono
    ORGANIC & BIOMOLECULAR CHEMISTRY 2 (23) 3442 - 3447 1477-0520 2004 Scientific journal 
    The boron trifluoride-catalyzed Rothemund condensations of phenylpropargylaldehyde with 4,7-dihydro-4,7-ethano-2H-isoindole or 3, 4-diethylpyrrole in dichloromethane at low temperature give 5,10,15,20-tetrakis(phenylethynyl) porphyrins bearing bicyclo [2.2.2] octadiene and octaethyl substituents, respectively. The former undergoes a retro Diels Alder reaction to afford 5, 10,15,20-tetrakis(phenylethynyl) benzoporphyrin quantitatively. The different conformations of the porphyrin periphery were determined by X-ray diffraction and their redox and spectroscopic properties have been investigated.
  • N Ono, T Yamamoto, N Shimada, K Kuroki, M Wada, R Utsunomiya, T Yano, H Uno, T Murashima
    HETEROCYCLES 61 433 - + 0385-5414 2003/12 Scientific journal 
    Incorporation of acenaphtho[1,2-c]pyrrole units into the pi-conjugated systems is very effective to get the narrow HOMO-LUMO gap materials, and the absorption spectra of pi-conjugated polymers, porphyrins, and boron dipyrromethene dyes fused with acenaphthene rings are extensively red-shifted.
  • H Uno, A Masumoto, N Ono
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 125 (40) 12082 - 12083 0002-7863 2003/10 Scientific journal 
    On heating, syn-diporphyrin zinc complexes fused with bis(ethano)dimethoxyanthracene, the crystal structure of which showed a unique trimeric assembly, extruded one ethylene molecule at 240-310 °C to give a porphyrin-naphthoporphyrin diad, and the second retro-Diels-Alder reaction and concomitant decomposition of the methoxy groups occurred at 280-350 °C to give the anthraquinone-fused diporphyrin, while the first thermal conversion of the anti-diporphyrin zinc complex occurred in a much lower temperature range (180-230 °C). Copyright © 2003 American Chemical Society.
  • H Uno, T Ishikawa, T Hoshi, N Ono
    TETRAHEDRON LETTERS 44 (28) 5163 - 5165 0040-4039 2003/07 Scientific journal 
    Porphyrins fused with dihydroxylated bicyclo[2.2.2]octadiene at beta-positions were quantitatively converted to the corresponding tetrabenzoporphyrins either by treatment with NaH in DMF at 0degreesC or on boehmite at room temperature. (C) 2003 Published by Elsevier Science Ltd.
  • H Uno, Y Fumoto, K Inoue, N Ono
    TETRAHEDRON 59 (5) 601 - 605 0040-4020 2003/01 Scientific journal 
    From X-ray analyses of 3,7,11-triphenylcyclonona[1,2-b;4,5-b';7,8-b"]tripyrrole-2,6,10-tricarboxylate (CNTP 1), the molecules existed as saddle forms in both crystals of 1.3ClPh and 1.1/2CHCl(3), In the former crystal, hydrogen bonds between pyrrolic hydrogen and ester carbonyl oxygen spread two-dimensionally, forming molecular sheets, between which the solvent molecules were included, while two independent molecules were bounded three-dimensionally by the hydrogen bonds in the latter. In CDCl3, CNTP was observed to adopt a crown form, while interconversion of the conformers was observed in C5D5N. (C) 2003 Elsevier Science Ltd. All rights reserved.
  • H Uno, K Inoue, T Inoue, N Ono
    ORGANIC & BIOMOLECULAR CHEMISTRY 1 (21) 3857 - 3865 1477-0520 2003 Scientific journal 
    Acid-catalyzed oligomerization of 2-(hydroxymethyl) pyrroles bearing C6F5, 2,6-Cl2C6H3, CF3 and CO2Et groups at beta-positions was examined. The reaction of ethyl pyrrole-3-carboxylates gave a mixture of oligomers and type I isomers of porphyrinogens and hexaphyrinogens were isolated when the other beta-substituents were sufficiently bulky, for example, mesityl, 2,6-Cl2C6H3 and C6F5 groups. On the other hand, the pyrroles having other electron-withdrawing groups afforded porphyrinogens as the only isolable products.
  • Y Shimizu, Z Shen, S Ito, H Uno, J Daube, N Ono
    TETRAHEDRON LETTERS 43 (47) 8485 - 8488 0040-4039 2002/11 Scientific journal 
    Bi- and tri-isothianaphtliene-alpha,omega-dicarbaidehydes were easily synthesized by using 4,7-dihydro-4,7-ethano-2-benzo[c]thiophene as a useful synthon of 1,3-unsubstituted isothianaphthene. The UV-vis absorptions of oligo-isothianaphthene derivatives exhibit a considerable bathochromic shift compared to the cases of other oligo-thiophene analogs, and their cyclic voltammetry shows narrowed HOMO-LUMO gaps of the isothianaphthene derivatives. This indicates high efficiency of pi-electron delocalization in the oligo-isothianaphthenes along the conjugated backbone. (C) 2002 Elsevier Science Ltd. All rights reserved.
  • T Murashima, K Nishi, K Nakamoto, A Kato, R Tamai, H Uno, N Ono
    HETEROCYCLES 58 301 - 310 0385-5414 2002/11 Scientific journal 
    reaction of nitropyridine derivatives with ethyl isocyanoacetate in the presence of 1,8-diazabicyclo[5.4.0]undecene proceeded tandem cyclization to give polycyclic pyrrolopyridines or imidazopyridines. On the other hand, N-protected 3-nitro- and 5-nitropyridones and N,N-diprotected 5-nitrouracil gave corresponding bicyclic pyrroles in good yields under the similar conditions.
  • H Uno, Y Kitawaki, N Ono
    CHEMICAL COMMUNICATIONS (2) 116 - 117 1359-7345 2002 Scientific journal 
    Porphyrin dimers were prepared from beta,beta'-dipyrrole derivatives via the double pyrrolylmethylation followed by double [2+2] MacDonald porphyrin synthesis.
  • 抗菌デスクマットによる接触皮膚炎の2例
    町野 博, 八幡 陽子, 倉本 誠, 宇野 英満
    西日本皮膚科 日本皮膚科学会-西部支部 63 (6) 668 - 668 0386-9784 2001/12 [Peer-reviewed]
  • S Ito, K Nakamoto, H Uno, T Murashima, N Ono
    CHEMICAL COMMUNICATIONS 1 (24) 2696 - 2697 1359-7345 2001/12 Scientific journal 
    A soluble porphyrin dimer linked with bicyclo[2.2.2]octadiene was converted in to insoluble conjugated porphyrin dimer by heating at 200 degreesC, this provides a new strategy for the process control of conjugated porphyrins.
  • Mitsuo Wada, Satoshi Ito, Hidemitsu Uno, Takashi Murashima, Noboru Ono, Toshiyuki Urano, Yasuteru Urano
    Tetrahedron Lett. 42 (38) 6711 - 6713 0040-4039 2001/09 
    A new class of boron dipyrromethene (BDP) dyes fused with rigid bicyclo[2.2.2]octadiene units are prepared, which are converted into benzo BDP dyes via a retro Diels-Alder reaction; the absorption and fluorescence spectra of the new dyes are discussed. © 2001 Elsevier Science Ltd. All rights reserved.
  • A. Kunugi, Y. Kudo, H. Uno
    J. Electroanal. Chem. 507 (1/2) 37 - 45 0022-0728 2001/07 
    The electroreduction of β-hydroxy γ,δ-unsaturated sulfones did not lead to the formation of a double bond between the α and β carbons, but a certain β-hydroxy γ,δ-unsaturated sulfone (3bA) in the absence of proton donors gave a cyclohexenol derivative. This compound was derived from fission of a carbon-carbon bond between α- and β-positions followed by recombination of the two fragments in the tandem Michael and aldol reactions. © 2001 Elsevier Science B.V.
  • Hidemitsu Uno, Yoshitsugu Sano, Akira Kunugi
    Electrochim. Acta 46 (12) 1879 - 1890 0013-4686 2001/03 
    The synthesis of polyenes by electrolysis of β-acetoxy phenyl sulfones having some double bonds was studied in acetonitrile using a Hg pool cathode and a sacrificial Mg anode. Most unsaturated β-acetoxy phenyl sulfones were subject to the electroreductive elimination of both the acetoxy and the sulfonyl groups, but did not give the desired polyenes because of partial hydrogenation of double bonds. The electrolytic reduction of a β-acetoxy phenyl sulfone having a trifluoromethyl group at the β-position was subjected to such 1,2-elimination followed by reductive removal of all fluorine atoms to afford the corresponding unsaturated hydrocarbons, whereas β-acetoxy phenyl sulfones having a fluorine atom at the α-position gave the desired fluoro-olefins in high yields. All saturated β-acetoxy phenyl sulfones afforded the desired alkenes in high yields.
  • Yumiko Fumoto, Hidemitsu Uno, Takashi Murashima, Noboru Ono
    Heterocycles 54 705 - 720 0385-5414 2001/02 
    A meso-unsubstituted porphyrin having a formyl group was synthesized both from a mono(ethoxycarbonyl)porphyrin by reduction with LiA1H4 followed by oxidation with MnO2 and from a monocyanoporphyrin by reduction with DIBALH. The monoethoxycarbonyl and monocyanoporphyrins were prepared by the acid catalyzed mixed condensation of the corresponding 4-ethoxycarbonyl- and 4-cyano-2-(hydroxymethyl)pyrroles with 3-mesityl-4-methyl-2-(hydroxymethyl)pyrrole. A porphyrin with four formyl groups at the β-positions was prepared from ethyl 4-(dithiolan-2-yl)-3-methylpyrrole-2-carboxylate by the sequential treatment of LiA1H4, p-TsOH, and NBS. Cyclic voltammetry and UV-VIS spectroscopic analyses of these porphyrins revealed the highly electron-deficient property of the porphyrin chromophore.
  • Satoshi Ito, Hikaru Watanabe, Hidemitsu Uno, Takashi Murashima, Noboru Ono, Yu Chen Tsai, Richa, G. Compton
    Tetrahedron Lett. 42 (4) 707 - 710 0040-4039 2001/01 
    Polypyrrole annelated with bicyclo[2.2.2]octene provides a new material that possesses a raised HOMO band, extended conjugation and a rigid porous structure. © 2001 Elsevier Science Ltd.
  • Y. Fumoto, H. Uno, K. Tanaka, M. Tanaka, T. Murashima, N. Ono
    Synthesis (3) 399 - 402 0039-7881 2001/01 
    meso-Unsubstituted porphyrin dimers linked with 1,3- and 1,4-phenylenes were prepared from the corresponding phenylenedipyrroles by double [3+1] MacDonald condensation in 16% and 27% yields, respectively. These dipyrroles were in turn prepared from tere- and iso-phthalaldehydes in respective yields of 23% and 41% via the 3-step reactions involving the modified Barton-Zard reaction.
  • Satoshi Ito, Hidemitsu Uno, Takashi Murashima, Noboru Ono
    Tetrahedron Lett. 42 (1) 45 - 47 0040-4039 2001/01 
    Benzoporphyrins with octamethoxycarbonyl groups 8a,b are obtained in near 100% yields by heating the corresponding tetra(bicyclo)porphyrins 7a,b at 200°C without affecting the ester moiety. © 2000 Elsevier Science Ltd.
  • H Uno, K Sakamoto, E Honda, K Fukuhara, N Ono, J Tanaka, M Sakanaka
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (3) 229 - 238 1472-7781 2001 Scientific journal 
    Regioselective halogenation of 3-acetoxymethyl-7-chloro-5,8-dimethoxy-1-naphthol 5 was achieved by DBH or I-2/N-methylmorpholine to give the corresponding 2-halogeno-1-naphthols 8 and 11, which were converted to 1-methoxymethoxy-3-(alk-2-ynoyloxymethyl)-2-halogenonaphthalenes 17 and 18 in good yields. An intramolecular acyl-transfer reaction of the 2-halogenonaphthalenes triggered by halogen-lithium exchange with BuLi at -78 degreesC gave 1-methoxymethoxy-2- alkynoyl-3-(hydroxymethyl)naphthalenes 21 in high yields. After protection of the hydroxymethyl group as a benzoate, formation of a gamma -pyrone ring was easily achieved by deprotection of the methoxymethyl group followed by spontaneous 6-endo ring closure under mildly acidic conditions. The pyrone derivative having a 1-methylpropyl group was successfully converted to espicufolin 1.
  • H Uno, A Masumoto, E Honda, Y Nagamachi, Y Yamaoka, N Ono
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 1 (23) 3189 - 3197 1472-7781 2001 Scientific journal 
    Intramolecular condensation of 2-(acetonyl)-3-acyljuglone derivatives under basic conditions gave 1,6- and/or 1,8-dihydroxyanthraquinones depending on the conditions employed. Treatment of 6-[(3-acetyl-5-methoxy-1,4-dioxo-1,4-dihydro-2-naphthyl)methyl]-2,2-dimethyl-4H-1,3-dioxin-4-one with K2CO3, in alcohol brought about the intramolecular Knoevenagel-type reaction to give 3-hydroxy-8-methoxy-1-methyl-9,10-dioxo-9, 10-dihydro-anthracene-2-carboxylates in good yields, while the same naphthoquinone gave 4-hydroxy-5-methoxy-9,10-dioxo-9,10-dihydroanthracene-2-acetic acid in good yield by treatment with potassium bis(trimethylsilyl)amide (KHMDS). Chrysophanol, aloe-emodin, aloesaponarin I, and K 1115A were prepared in good yields.
  • H. Uno, K. Inoue, T. Inoue, Y. Fumoto, N. Ono
    Synthesis (15) 2255 - 2258 0039-7881 2001 Scientific journal 
    Ethyl pyrrole-2-carboxylates bearing trifluoromethyl and/or pentafluorophenyl groups at β-positions were converted to the corresponding α-free pyrroles in good yields by reduction with LiAlH4, oxidation with MnO2 and decarbonylation with Pd/C.
  • A Kunugi, A Jabbar, S Naitoh, M Yasuzawa, H Uno
    ELECTROCHEMISTRY 68 (12) 955 - 962 1344-3542 2000/12 Scientific journal 
    The introduction of sulfur atoms into trifluoromethylated alkenyl sulfones and chlorides were studied using a reactive sulfur-graphite electrode in N,N-dimethylformamide. A substrate, 2-(4-biphenylyl)-4,4,4-trifluoro-3-phenylsulfonyl-2-butenenitrile (1a) afforded a coupling compound bridged with a nitrogen atom of isothiazole and 1,2-dithiolane skeleton (2). 1-(4-Biphenylyl)-3,3,3-trifluoro-2-phenylsulfonylpropene (1b) without a cyano group gave a complex oligomeric compound (3) without the elimination of the phenylsulfonyl group. 2- (4-Biphenylyl)-3-chloro-4,4,4-trifluoro-2 butenenitrile (1c) having a chloro group as a leaving group gave 2,4-di (4-biphenylyl)-2,4-dicyano-1,5-bis (trifluoromethyl)-3,6-dithiabicyclo[3.1.0]hexane (4) and 2-(4-biphenylyl)-4,4,4-trifluoro-2-butenenitrile (5). Methyl 2-(4- biphenylyl)-3-chloro-4,4,4-trifluoro-2-butenoate (1d) having an ester group in the place of a cyano group afforded di-[2-(4 biphenylyl)-2-methoxycarbonyl-1 trifluoromethylethyl] disulfide (6). The formation of such sulfur-containing organofluorine compounds except for the oligomeric compound 3 is characterized as the addition of polysulfide anion(s) produced by electroreduction of elemental sulfur. followed by the elimination of the phenylsulfonyl or the chloro group.
  • T Ogawa, H Furuta, M Takahashi, A Morino, H Uno
    JOURNAL OF ORGANOMETALLIC CHEMISTRY 611 (1-2) 551 - 557 0022-328X 2000/10 Scientific journal 
    N-Confused tetraarylporphyrinatoantimony(V) dimethoxides were synthesized and their X-ray crystallographic structure, absorption spectra and voltammetric spectra were studied. X-ray crystallographic structure revealed neutral molecules with no counter anion. From the absorption spectra and voltammetric studies we estimated their energy gaps to be about 0.2 eV less than the corresponding porphyrinatoantimony(V). The axial ligands could easily be exchanged in solvent alcohol by acid promotion. These characteristics of N-confused porphyrinatoantimony(V) indicate that they are good candidates for the molecular wire component. (C) 2000 Elsevier Science S.A. All rights reserved.
  • LRC Barclay, MR Vinqvist, K Mukai, H Goto, Y Hashimoto, A Tokunaga, H Uno
    ORGANIC LETTERS 2 (18) 2841 - 2843 1523-7060 2000/09 Scientific journal 
    The antioxidant activity of curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) was determined by inhibition of controlled initiation of styrene oxidation, Synthetic nonphenolic curcuminoids exhibited no antioxidant activity; therefore, curcumin is a classical phenolic chain-breaking antioxidant, donating H atoms from the phenolic groups not the CH2 group as has been suggested (Jovanovic et at. J. Am. Chem, Sec. 1999, 121, 9677). The antioxidant activities of omicron-methoxyphenols are decreased in hydrogen bond accepting media.
  • H Uno, T Inoue, Y Fumoto, M Shiro, N Ono
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 122 (28) 6773 - 6774 0002-7863 2000/07 Scientific journal
  • H Uno, K Kasahara, N Ono
    HETEROCYCLES 53 (5) 1011 - + 0385-5414 2000/05 Scientific journal 
    In the presence of a Lewis acid, the Michael-type reaction of (3R)-5-tert-butyldimethylsiloxy-3-phenyl-1H-pyrrolo[1,2-c]oxazole (1) with nitro olefins smoothly occurred to give 7a-alkylated pyrrolo[1,2-c]oxazol-5-ones (2) in good yields. The products (2) were successfully transformed to a alpha-branched serine derivatives via reductive denitration followed by lactam-ring cleavage.
  • K Sakamoto, E Honda, N Ono, H Uno
    TETRAHEDRON LETTERS 41 (11) 1819 - 1823 0040-4039 2000/03 Scientific journal 
    An intramolecular acyl transfer reaction took place on treatment of 1-methoxymethoxy-3-(2-alkynoyloxy)methyl-2-iodonaphthalenes with n-BuLi at -78 degrees C to give 1-methoxymethoxy-2-alkynoyl-3-hydroxymethylnaphthalenes in high yields. After protection of the hydroxymethyl group as benzoates, formation of a phi-pyrone ring was easily achieved by deprotection of the MOM group followed by spontaneous 6-endo-digonal ring closure under mild acidic conditions. (C) 2000 Elsevier Science Ltd. All rights reserved.
  • H Uno, K Kasahara, N Nibu, S Nagaoka, N Ono
    JOURNAL OF ORGANIC CHEMISTRY 65 (6) 1615 - 1622 0022-3263 2000/03 Scientific journal 
    isomerization of tetraaryl tetrakis(trifluoromethyl) [4]radialenes was studied. When type II (all-Z) isomers of 5,6,7,8-tetraaryl-5,6,7,8-tetrakis(trifluromethyl)[4]radialenes were heated in tetralin at 170-200 degrees C, isomerization occurred to give mixtures of four [4]radialenes in a ratio of ca. I:II:III:IV = 1:10:5:1. However, when the isomeric mixtures were heated in the solid state-at the same temperature, selective isomerization took place to give type II isomers in good selectivity (>91%). Upon irradiation with light, the type II isomers first isomerized to mixtures of the four [4]radialene isomers (I:II:III:IV = 2:2:48:48) and then rearranged to cyclobuta[b]naphthalenes via a 6 pi-electrocyclic reaction followed by 1,3-hydrogen migration.
  • T Murashima, R Tamai, K Nishi, K Nomura, K Fujita, H Uno, N Ono
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (6) 995 - 998 0300-922X 2000 [Peer-reviewed]
     Scientific journal 
    Stable 2H-isoindoles with electron-withdrawing groups were prepared using the reaction of dinitrobenzene derivatives with isocyanoacetate in the presence of DBU. The use of acetonitrile as the solvent or a phosphazene base (BTPP) as a non-ionic base improved the yields. The structure was confirmed by X-ray crystallographic analysis of the compound 2e'. According to the X-ray analysis, this substance existed in the solid phase only as the 2H-isomer.
  • H Uno, S Ito, M Wada, H Watanabe, M Nagai, A Hayashi, T Murashima, N Ono
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (24) 4347 - 4355 1472-7781 2000 [Peer-reviewed]
     Scientific journal 
    Pyrroles fused with bicyclo[2.2.2]octene and bicyclo[2.2.1]heptene frameworks are prepared by a modified Barton-Zard method. Structures of these pyrroles and thermal behaviours of the former pyrroles are studied by X-ray and DSC analyses.
  • S Ito, N Ochi, T Murashima, H Uno, N Ono
    HETEROCYCLES 52 (1) 399 - 411 0385-5414 2000/01 Scientific journal 
    Various benzoporphyrins and their metal complexes were obtained in 100% yield by heating porphyrins fused with bicyclo[2.2.2]octadiene at 200 degrees C. This thermal (retro Diels-Alder) reaction proceeds very cleanly to give pure benzoporphyrins without further purification.
  • S Ito, N Ochi, H Uno, T Murashima, N Ono
    CHEMICAL COMMUNICATIONS (11) 893 - 894 1359-7345 2000 Scientific journal 
    A new synthesis of [2,3]naphthoporphyrins using 4,9-ethano-2H-benz[f]isoindole as a synthon of 2H-benz[f]- isoindole is described; soluble precursors of [2,3]naphthoporphyrins are converted into insoluble [2,3]naphthoporphyrins by simply heating at 290 degrees C.
  • Takashi Murashima, Ryuji Tamai, Keiji Nishi, Kentaroh Nomura, Ken-Ichi Fujita, Hidemitsu Uno, Noboru Ono
    Journal of the Chemical Society, Perkin Transactions 1 (6) 995 - 998 1470-4358 2000 Scientific journal 
    Stable 2H-isoindoles with electron-withdrawing groups were prepared using the reaction of dinitrobenzene derivatives with isocyanoacetate in the presence of DBU. The use of acetonitrile as the solvent or a phosphazene base (BTPP) as a non-ionic base improved the yields. The structure was confirmed by X-ray crystallographic analysis of the compound 2e′. According to the X-ray analysis, this substance existed in the solid phase only as the 2H-isomer. © The Royal Society of Chemistry 2000.
  • Hidemitsu Uno, Satoshi Ito, Mitsuo Wada, Hikaru Watanabe, Miho Nagai, Akiko Hayashi, Takashi Murashima, Noboru Ono
    Journal of the Chemical Society, Perkin Transactions 1 (24) 4347 - 4355 1470-4358 2000 Scientific journal 
    Pyrroles fused with bicyclo[2.2.2]octene and bicyclo[2.2.1]heptene frameworks are prepared by a modified Barton-Zard method. Structures of these pyrroles and thermal behaviours of the former pyrroles are studied by X-ray and DSC analyses. © The Royal Society of Chemistry 2000.
  • T Murashima, D Shiga, K Nishi, H Uno, N Ono
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (16) 2671 - 2675 1470-4358 2000 Scientific journal 
    Three series of dimers containing pyrrolo[3,4-e][2,1,3]benzothiadiazole units have been prepared by application of the Pd-catalyzed Suzuki coupling. The dependence of the HOMO-LUMO separation on coplanarity has been evaluated by means of electronic absorption spectra and cyclic voltammetry. The pyrrole dimer 5c shows a narrow HOMO-LUMO separation owing to its intrinsically planar structure, as confirmed by H-1 NMR.
  • Hidemitsu Uno, Yumi Nagamachi, Erina Honda, Akane Masumoto, Noboru Ono
    Chemistry Letters (9) 1014 - 1015 0366-7022 2000 Scientific journal 
    Treatment of 3-acyl-2-[(2,2-dimethyl-6-oxo-1,3-dioxin-4-yl)methyl]-5-methoxy-1,4-naphthoquino nes with K2CO3 in an alcohol brought about the intramolecular condensation to give 1-alkyl-3-hydroxy-8-methoxy-9,10-anthraquinone-2-carboxy-lates in good yields, while the same naphthoquinone gave 1-hydroxy-8-methoxy-9,10-anthraquinone-3-acetic acid in good yield by treatment with KHMDS.
  • Y Fumoto, H Uno, S Ito, Y Tsugumi, M Sasaki, Y Kitawaki, N Ono
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (17) 2977 - 2981 1470-4358 2000 Scientific journal 
    Ethyl 4-formylpyrrole-2-carboxylates were prepared from nitroacetaldehyde dimethyl acetal in 9-50% yields using the Barton-Zard reaction. These formylpyrroles were successfully transformed to cycloalkano-oligopyrroles. The conformation of cyclononatripyrroles in CDCl3 was found to be a crown form based on the NMR analysis, while cyclododecatetrapyrroles were in two interconverting boat and chair conformations.
  • Y Fumoto, T Eguchi, H Uno, N Ono
    JOURNAL OF ORGANIC CHEMISTRY 64 (17) 6518 - 6521 0022-3263 1999/08 Scientific journal
  • H Uno, N Nibu, N Misobe
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 72 (6) 1365 - 1375 0009-2673 1999/06 Scientific journal 
    The coupling reaction of perfluoroalkylated 2-aryl-1,1-dibromoalkenes using zinc and copper(I) bromide gave stereoisomeric mixtures of [3]cumulenes and [4]radialenes. The ratio of [3]cumulenes and [4]radialenes mainly depended upon the reaction temperature and the electronic character of the aryl group. When the coupling reaction was carried out at -40 degrees C, (E)- and (Z)-[3]cumulenes were obtained in good selectivity and only trace amounts of [4]radialenes were detected by a (FNMR)-F-19 analysis. On the other hand, a similar reaction at -60 degrees C afforded a considerable amount of [4]radialene isomers. When the cis-[3]cumulenes were heated at an appropriate temperature, selective isomerization to trans-[3]cumulenes occurred.
  • H Uno, K Sakamoto, E Honda, N Ono
    CHEMICAL COMMUNICATIONS (11) 1005 - 1006 1359-7345 1999/06 Scientific journal 
    l(S)-Espicufolin was synthesized from 1,4-dimethoxybenzene in 16 steps via an intramolecular acyl-transfer reaction as the key step; the absolute stereochemistry at the 14-position of natural espicufolin was determined to be R.
  • Hidemitsu Uno, Masanori Tanaka, Takashi Inoue, Noboru Ono
    Synthesis (3) 471 - 474 0039-7881 1999/01 
    Reaction of α-trifluoromethyl, α-cyano, and α-ethoxycarbonyl alkenyl sulfones with ethyl isocyanoacetate in the presence of a base gave 4- substituted pyrrole-2-carboxylates in moderate to good yields.
  • A Kunugi, K Hayashi, H Yumoto, H Uno
    ELECTROCHIMICA ACTA 44 (17) 2899 - 2907 0013-4686 1999 Scientific journal 
    Electrosynthesis of organic polysulfides from cumulenes having two trifluoromethyl groups was studied using a sacrificial sulfur-graphite electrode. The reaction with these cumulenes led to dimeric compounds with a 1,2,5,6-tetrathiocin skeleton as the major product, accompanied with 7- and 8-membered ring compounds with five and six sulfur atoms such as pentathiepins and hexathiocins in minor amounts. These dimeric compounds will be produced by further reaction of the intermediate products such as 7- and 8-membered ring compounds with the polysulfide anion(s). These cyclic compounds will be formed by a Michael addition of the polysulfide anion(s) (S-8(2-) and/or S-6(2-)) produced by electroreduction of elemental sulfur. Coulometric n-values were less than 1 e per molecule of the cumulene in spite that it needs 2 e or above per half molecules of the dimeric compound. (C) 1999 Elsevier Science Ltd. All rights reserved.
  • A Kunugi, MA Jabbar, K Mori, H Uno
    ELECTROCHIMICA ACTA 44 (25) 4583 - 4592 0013-4686 1999 Scientific journal 
    Electrosynthesis of sulfur-containing compounds from vinyl sulfones having a cyano group was studied using a reactive sulfur-graphite electrode, 3-Aryl-2-phenylsulfonylpropenenitriles (la-c) and 2-phenyl-3-phenylsulfonylpropenenitrile (Id) were used as vinyl sulfones. In acetonitrile, la-c having geminal cyano and sulfonyl groups gave dimeric 5-arylisothiazoles bridged with two or three sulfur atoms at the 3-position in moderate yields. Similarly, Id having vicinal cyano and sulfonyl groups yielded dimeric 4-phenylisothiazole bridged with two sulfur atoms together with 3-[(Z)-2-cyano-2-phenylethenylthio]-5-phenylisothiazole. In N,N-dimethylformamide products which involve the solvent were not obtained and the result was almost the same as those in acetonitrile. This electrosynthesis of sulfur-containing compounds is characterized as elimination of a phenylsulfonyl group accompanying the addition of polysulfide anion(s) produced by electroreduction of elemental sulfur. (C) 1999 Elsevier Science B.V. All rights reserved.
  • S Ito, H Uno, T Murashima, N Ono
    CHEMICAL COMMUNICATIONS (22) 2275 - 2276 1359-7345 1999 Scientific journal 
    Porphyrins fused with bicyclo[2.2.2]octene frameworks are prepared; the bicyclo[2.2.2] units rigidify the porphyrin ring to maintain planar conformations in solution.
  • Hidemitsu Uno, Noboru Mizobe, Youtarou Yamaoka, Noboru Ono
    Heterocycles 48 635 - 640 0385-5414 1998/12 
    In the presence of BF3·OEt2, the reaction of (3R)-5-t-butyldimethylsiloxy-6-methyl-3-phenyl-1H-pyrrolo[1,2-c]oxazole (3) with aliphatic aldehydes in ether occurred stereoselectively to give the corresponding (3R,7aR,1'R)-isomers (4a and 6a) as the major products, while the similar reaction with aromatic aldehydes afforded the (3R,7aR,1'S)-isomers (7b, 8b, and 9b) predominantly. The product (7b) from the reaction with benzaldehyde was successfully transformed to a lactacystin analogue.
  • S Ito, T Murashima, H Uno, N Ono
    CHEMICAL COMMUNICATIONS (16) 1661 - 1662 1359-7345 1998/08 Scientific journal 
    Heating 4,7-dihydro-4,7-ethano-2H-isoindole at 200 degrees C induces the retro-Diels-Alder reaction to give isoindole in essentially quantitative yield, which can be applied to a new synthesis of tetrabenzoporphyrins and monobenzoporphyrins.
  • T Murashima, K Hirai, Y Une, Y Uchihara, H Uno, N Ono
    TETRAHEDRON LETTERS 39 (30) 5397 - 5400 0040-4039 1998/07 Scientific journal 
    Pyrroles having long alkoxy groups on the 3-position are prepared and utilized as precursors for polypyrrolenevinylenes. The resulting polymers exhibit high solubility not only in a moderately polar solvent but also in a nonpolar solvent such as hexane. These polymers have deep-blue color in the neutral state, while in the doped state the color is completely faded to transparent. (C) 1998 Elsevier Science Ltd. All rights reserved.
  • MA Jabbar, S Bito, A Kunugi, H Uno
    ELECTROCHIMICA ACTA 43 (21-22) 3165 - 3173 0013-4686 1998 Scientific journal 
    The controlled potential electrolysis of alpha,beta-unsaturated sulfone 2 and sulfoxide 3 bearing a trifluoromethyl group in N,N-dimethylformamide containing excess benzoic acid was subjected to an electroreductive desulfurization to afford the corresponding trifluoromethyl-substituted olefin 4 in good yields. The use of a sacrificial Mg anode resulted in a large increase in the yield of 4. Furthermore, the use of the sacrificial Mg anode in the absence of the acid gave unexpected products 5 and 6 from 2, and 7 and 8 from 3, respectively, with concomitant formation of 4. In the presence of acetic anhydride or carbon dioxide any carbonylated product was not obtained and the simple reduction to 4 occurred predominantly. (C) 1998 Elsevier Science Ltd. All rights reserved.
  • H Uno, N Nibu, Y Yamaoka, N Mizobe
    CHEMISTRY LETTERS (2) 105 - 106 0366-7022 1998 Scientific journal 
    Coupling reaction of 2-aryl-1,1-dibromo-3,3,3-trifluoropropenes using zinc and copper(I) bromide gave [4]radialenes in almost statistic ratios in addition to [3]cumulenes. Thermal dimerization of the cumulenes in neat gave mixtures of four isomeric [4]radialenes in moderate yields. When the isomers were heated in solid at appropriate temperatures, thermal isomerization occurred to afford type II (all-Z) isomers of [4]radialenes in high selectivity.
  • Hidemitsu Uno, Hidemitsu Uno, Jack E. Baldwin, Ian Churcher, Andrew T. Russell, Andrew T. Russell
    Synlett 1997 390 - 392 0936-5214 1997/12 
    The stereochemistry of the Lewis acid catalysed Mukaiyama-type aldol reaction of 5-tert-butyldimethylsiloxy-3-phenyl-1H-pyrrolo[1,2-e]oxazoles with isobutyraldehyde was dependant on the nature of the Lewis acid, SnCl4 and BF3·OEt2 giving predominantly isomeric products.
  • A Kunugi, K Kuwamura, H Uno
    ELECTROCHIMICA ACTA 42 (15) 2399 - 2406 0013-4686 1997 Scientific journal 
    Electrosynthesis of sulfur-containing organic compounds from cumulene derivatives was studied using a sacrificial sulfur-graphite electrode. 1,1-Di-p-chlorophenylbuta-1,2,3-triene (1a),1,1-di-p-chlorophenyl-4,4-di-p-methylphenylbuta-1,2,3-triene (1b), 1,1,4,4-tetraphenylbuta-1,2,3-triene (1c) and 1,1-di-p-methoxyphenyl-4,4-diphenylbuta-1,2,3-triene (Id) were used as cumulenes. With la, Lb and Ic, 7-membered ring compounds with five sulfur atoms such as pentathiepins 2a, 2b and 2c were produced as the major products accompanied with dimeric compounds 3a, 3b and 3c which had a 1,2,5,6-tetrathiocin skeleton in minor amounts, respectively. However, Id, which is the most difficult to be reduced among the cumulenes studied, did not give sulfur-containing organic compounds. Yields of 2a, 2b and 2c decreased a little by the addition of a proton donor such as benzoic acid. Main products 2 will be initiated by a Michael addition of the polysulfide anion(s) (S-8(2-) and/or S-6(2-)) produced by electroreduction of elemental sulfur. By-products 3 will be probably produced by further reaction of 2 with the polysulfide anion(s). (C) 1997 Elsevier Science Ltd.
  • T Murashima, R Tamai, K Fujita, H Uno, N Ono
    TETRAHEDRON LETTERS 37 (46) 8391 - 8394 0040-4039 1996/11 Scientific journal 
    Two classes of nitro heteroaromatic compounds such as quinoxalines 7a,b and benzothia/selenadiazoles 7c,d with ethyl isocyanoacetate in the presence of 1,8-diazabicyclo[5,4,0]undec-7-ene gave the corresponding pyrimidine N-oxides 8a-d, whilst, in contrast, use of proazaphosphatrane 2 or iminophosphorane 4 as a base under similar conditions gave the corresponding pyrroles 9a-d. Copyright (C) 1996 Elsevier Science Ltd
  • N Ono, K Matsumoto, T Ogawa, H Tani, H Uno
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (15) 1905 - 1910 0300-922X 1996/08 Scientific journal 
    A new synthesis of push-pull dienes such as 4-nitro-1-phenylthiopenta-1,3-diene 4 and 1-dialkylamino-4-nitropenta-1, 3-diene 5, is described, The X-ray crystal analysis shows that 4-nitro-1-(pyrroidin-1-yl)penta-1,3-diene 5a is essentially planar in an E,E-configuration with r(C-C) = 1.42(1) Angstrom and r(C-C) = 1.35(1) and 1.371(9) Angstrom. Compounds 5 showed a large solvatochromic effect similar to that of merocyanine dyes. Molecule 5a exhibits second harmonic generation (SHG) activity whose efficiency is 2.5 times that of urea (determined by a powder method at 1064 nm). For 5a, the molecular nonlinearity mu beta is estimated to be 1200 x 10(-48) esu which is calculated from the Pocket coefficient (r(33)) determined by electrooptic measurements of poled polymers of 5a in poly(methyl methacrylate) at 1300 nm, This value is relatively large for such small conjugated molecules, where donors and accepters are bridged by only 4 pi electron systems.
  • H Uno, K Oka, H Tani, Y Kawada, N Ono
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 69 (6) 1763 - 1767 0009-2673 1996/06 Scientific journal 
    1-Phenylsulfanyl-2,2,2-trifluoroethyl isocyanide (2a) readily and selectively trimerized to 4,6-bis(phenylsulfanyl)-1- (1-phenylsulfanyl-2,2,2-trifluoroethyl)-5-(2,2,2- trifluoroethylideneamino)-2-trifluoromethyl-1,2-dihydropyrimidine (5) at room temperature, while other alpha-phenylsulfanyl isocyanides such as phenyl(phenylsulfanyl)methyl isocyanide (2b) are stable. Heating of 2b resulted in formation of the corresponding nitrile as well as diphenyl disulfide and [bis(phenylsulfanyl)methyl]benzene.
  • T Murashima, K Fujita, K Ono, T Ogawa, H Uno, N Ono
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (12) 1403 - 1407 0300-922X 1996/06 Scientific journal 
    Nitro heteroarenes react with ethyl isocyanoacetate in the presence of 1,8-diazabicyclo [5,4,0]undecene (DBU) to give pyrroles or pyrimidine N-oxide depending on the structure of the starting nitro compounds, For example, 4-nitro-2,1,3-benzothiadiazole 3a reacted with ethyl isocyanoacetate to give ethyl 2,1,3-benzothiadiazolo [3,4-c] pyrrole-2-carboxylate 4a (33%), while a similar reaction with 5-nitro-2,1,3-benzothiadiazole 3b gave the corresponding compound 4b (21%) as a sole product, A plausible mechanism for these reactions is presented.
  • T Murashima, Y Uchihara, N Wakamori, H Uno, T Ogawa, N Ono
    TETRAHEDRON LETTERS 37 (18) 3133 - 3136 0040-4039 1996/04 Scientific journal 
    Pyrroles fused with crown ethers are prepared by the reaction of 3,4-dihydroxy pyrrole 1 and polyethylene glycol ditosylate 2 in the presence of cesium fluoride using a convenient high dilution method. These pyrroles can be converted into the corresponding porphyrins with four crown ether moieties, which are expected to form ion channels. Copyright (C) 1996 Elsevier Science Ltd
  • H Uno, T Kinoshita, K Matsumoto, T Murashima, T Ogawa, N Ono
    JOURNAL OF CHEMICAL RESEARCH-S (2) 76 - & 0308-2342 1996/02 Scientific journal 
    The reaction of 2-nitroalkenyl sulfides 2 and 2-nitroenamines 3 with ethyl isocyanoacetate in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene gives ethyl 1-hydroxypyrazole-3-carboxylates 4 in moderate to good yields.
  • T Murashima, N Wakamori, Y Uchihara, T Ogawa, H Uno, N Ono
    MOLECULAR CRYSTALS AND LIQUID CRYSTALS SCIENCE AND TECHNOLOGY SECTION A-MOLECULAR CRYSTALS AND LIQUID CRYSTALS 278 165 - 171 1058-725X 1996 Scientific journal 
    Pyrroles substituted with long alkoxy groups are prepared by the reaction of iminodiacetic acid dimethyl ester and dimethyl oxalate and the subsequent alkylation. These pyrroles are good precursor molecules for the corresponding porphyrins, which are expected to form an ordered columnar mesophase and are able to co-ordinate to various metals.
  • Akira Kunugi, Shinya Mori, Seiji Komatsu, Hiroshi Matsui, Hidemitsu Uno, Katsuji Sakamoto
    Electrochimica Acta 40 (7) 829 - 835 0013-4686 1995 Scientific journal 
    The electrolytic reduction of 1-fluoro-2-(4-biphenylyl)vinyl phenyl sulphoxide (1) in nonaqueous media involves desulphinylation, defluorination followed by reduction of the sulphinyl group, and reduction to the corresponding sulphide, resulting in the formation of 1-fluoro-2-(4-biphenylyl)ethylene (2), 2-(4-biphenylyl)vinyl phenyl sulphide (3) and 1-fluoro-2-(4-biphenylyl)vinyl phenyl sulphide (4). Distribution of these products is greatly dependent on the proton donors such as phenol, acetic acid and benzoic acid. In the absence of proton donors, the yields of products are low. The controlled potential electrolysis of 1 in N,N-dimethylformamide containing carbon dioxide was subjected to a substituting carboxylation to afford 2-fluoro-3-(4-biphenylyl)-propenoic acid (6), with concomitant formation of 2 and 3. © 1995.
  • H UNO, JE BALDWIN, AT RUSSELL
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 116 (5) 2139 - 2140 0002-7863 1994/03
  • Akira Kunugi, Kenji Yamane, Mikito Yasuzawa, Hiroshi Matsui, Hidemitsu Uno, Katsuji Sakamoto
    Electrochimica Acta 38 (7) 1037 - 1041 0013-4686 1993 Scientific journal 
    The electrolytic reduction of 1-fluoro-2-arylvinyl phenyl sulphones in acetonitrile involves cleavage of carbon-sulphur and/or carbon-fluorine bonds, resulting in the formation of 1-fluoro-2-aryl-ethylenes and arylethylenes with a molar ratio of about 1:1. The coulometric n-values are about three electrons per molecule, in the presence of efficient proton donors such as phenol, acetic acid and benzoic acid, and at all the following electrodes: mercury, platinum, lead and glassy carbon. In the absence of proton donors, the yields of 1-fluoro-2-arylethylenes and arylethyelens are very low, the n-value be about 1. © 1993.
  • H UNO, A YAYAMA, H SUZUKI
    TETRAHEDRON 48 (39) 8353 - 8368 0040-4020 1992/09 Scientific journal 
    Heating a DMSO solution of 4-(perfluoro-n-alkyl)-4-hydroxy-2,5-cyclohexadien-1-one (4-perfluoroalkyl-4-quinols) in the presence of a catalytic amount of base brought about 1,2-migration of the perfluoroalkyl group to give 2-(perfluoro-n-alkyl)hydroquinone or 5-(perfluoro-n-alkyl)-2-cyclohexene-1,4-dione depending upon the substitution pattern of the quinol. The similar rearrangement of 4-perfluoroisopropyl-4-hydroxy-2,5-cyclohexadien-1-one occurred very smoothly at room temperature under the basic conditions. 5-Hydroxy-4-methyl-5-perfluorooctyl-1-propyl-3-pyrrolin-2-one underwent the base-induced rearrangement to afford a perfluorooctylated succinimide derivative. On the other hand, 5-hydroxy-3-methyl-5-perfluorooctyl-1-propyl-3-pyrrolin-2-one and 5-hydroxy-1-isobutyl-5-perfluorooctyl-3-pyrrolin-2-one did not suffer any rearrangement, although their structures were very similar to the 4-methylated one.
  • Hidemitsu Uno, Shin-ichiro Okada, Tetsushi Ono, Yasukazu Shiraishi, Hitomi Suzuki
    Journal of Organic Chemistry 57 (5) 1504 - 1513 1520-6904 1992/02 Scientific journal 
    In the presence of BF3·OEt2, (perfluoroalkyl)lithiums generated in situ from the reaction of primary perfluoroalkyl iodides and MeLi_‒LiBr reacted with imines, azines, and nitrones to afford perfluoroalkylated nitrogen-containing compounds in moderate to good yields. This method was successfully applied to the preparation of a (perfluoroalkyl) glycine and optically active perfluoroalkylated amines. © 1992, American Chemical Society. All rights reserved.
  • H UNO, S OKADA, H SUZUKI
    TETRAHEDRON 47 (32) 6231 - 6242 0040-4020 1991/08 Scientific journal 
    In the presence of boron trifluoride, perfluoroalkyllithiums generated in situ from the reaction of n-perfluoroalkyl iodides with methyllithium-lithium bromide smoothly added to a carbon-nitrogen double bond of bicyclic azaarenes and diazines to give the corresponding perfluoroalkylated dihydro heterocycles, which often underwent spontaneous aromatization in air. Perfluroalkylation occurred preferentially at the carbon next to nitrogen in azaarenes even when the carbon atom was occupied by an alkyl substituent. Only one exception observed was the reaction of acridine where a perfluoroalkyl group was introduced at 9 position.
  • Hidemitsu Uno, Shin‐Ichiro Okada, Hitomi Suzuki
    Journal of Heterocyclic Chemistry 28 (2) 341 - 346 1943-5193 1991 Scientific journal 
    1‐Substituted 1,2‐dihydroisoquinolines, derived from isoquinoline and organolithium reagents, readily undergo autoxidation to lead to 4‐isoquinolinols in moderate yields. Copyright © 1991 Journal of Heterocyclic Chemistry
  • H. Uno, Y. Matsushima, T. Tasaka, H. Suzuki
    Bulletin of the Chemical Society of Japan 63 (1) 293 - 295 0009-2673 1990 Scientific journal 
    Vinyl perfluoroalkyl ketones formed in situ from the reactions of perfluoroalkyllithiums with ethyl acrylate can easily be trapped with thiouronium and amidinium salts to give 4-(perfluoroalkyl)tetrahydropyrimidines in moderate to good yields. Similarly, ethynyl perfluoroalkyl ketones generated in situ can be converted to 4-(perfluoroalkyl)pyrimidines, although the yields are low.
  • Hidemitsu Uno, Ken Ichi Goto, Noriko Watanabe, Hitomi Suzuki
    Journal of the Chemical Society, Perkin Transactions 1 (2) 289 - 295 1472-7781 1989/12 
    The Lewis acid-promoted reaction of 1-nitroalka-1,5-(or 1,6-)dienes with allylic stannanes has been studied. In the presence of TiCl4′ 1-nitrohexa-1,5-diene reacted smoothly with allyltrimethylstannane to give a diastereoisomeric mixture of 6-allyl-3a,4,5,6-tetrahydro-3H-cyclopent[c] isoxazoles, while the reaction using AlCl3 as catalyst led to an allylated cyclohexanone oxime derivative in good yield. The similar reaction of 1-nitrohepta-1,6-diene, however, gave a bicyclic dihydroisoxazole irrespective of the Lewis acids employed. In the latter case, nitrite oxide equivalents derived from 1-nitroalka-1,6-dienes underwent a stepwise cycloaddition as shown by the lack of stereospecificity in the reactions of (1E,6Z)-1-nitro-7- phenylhepta-1,6-diene and (1E,6Z)-1-nitro-octa-1,6-diene.
  • H UNO, Y SHIRAISHI, H SUZUKI
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 62 (8) 2636 - 2642 0009-2673 1989/08 Scientific journal 
    © 1989 The Chemical Society of Japan. A variety of esters react with perfluoroalkyllithiums in situ generated from perfluoroalkyl iodides and methyllithium to give perfluoroalkyl ketones in good yields. Perfluoroalkyllithiums add to α,β-unsaturated esters only in the 1,2-addition mode even in the presence of copper salt. Exception was observed in the reaction with maleates where perfluoroalkylated succinic esters and normal 1,2-addition products are obtained in comparable amounts.
  • H UNO, K GOTO, N WATANABE, H SUZUKI
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (2) 289 - 295 0300-922X 1989/02 [Peer-reviewed]
     Scientific journal
  • H. Uno, T. Terakawa, H. Suzuki
    Synthesis (5) 381 - 382 0039-7881 1989/01
  • Hidemitsu Uno
    Journal of Organic Chemistry 51 (3) 350 - 358 1520-6904 1986 Scientific journal 
    Total syntheses of pyranonaphthoquinone antibiotics eleutherin, isoeleutherin, nanaomycin A, and deoxyfrenolicin are described. The crucial step in the route is a regioselective allylation of alkanoyl quinones with allylsilanes and allylstannanes. The allylated products are easily converted to pyranonaphthoquinones by either intramolecular Michael addition or oxymercuration or phenylseleno etherification. © 1986, American Chemical Society. All rights reserved.
  • H UNO, Y NARUTA, K MARUYAMA
    TETRAHEDRON 40 (22) 4725 - 4741 0040-4020 1984 Scientific journal 
    Efficient syntheses of(1+-)-aklavinones; (±)-aklavinone (1), (±)-auramycinone (2), and (±)-13-methylaklavinone (3), are described. A key process of the tetracyclic ring construction in these syntheses is ia stereocontrolled "zipper" bicyclo-cyclization using a KH-Kryptofix 222 (4,7,13,16,21,24-hexaoxa-1.10-diazabicyclo [8.8.8]hexacosane) cryptate as a base. The reaction mechanism is discussed, too. © 1984.
  • Y NARUTA, M KASHIWAGI, Y NISHIGAICHI, H UNO, K MARUYAMA
    CHEMISTRY LETTERS (11) 1687 - 1690 0366-7022 1983 [Peer-reviewed]
     Scientific journal
  • Y NARUTA, H UNO, K MARUYAMA
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS (24) 1277 - 1278 0022-4936 1981 Scientific journal 
    (±)-Eleutherin (1) and (±)-isoeleutherin (3) are prepared by intramolecular cyclization to the naph- thopyrans of 2-acetyl-3-allyl-8-methoxy-l,4-naphthoquin- one, which is itself obtained by the Lewis acid-mediated allylation of 2-acetyl-8-methoxy-l,4-naphthoquinone (5) with allyltrimethylstannane (7). © 1981, The Royal Society of Chemistry. All Rights Reserved.
  • Y NARUTA, H UNO, K MARUYAMA
    NIPPON KAGAKU KAISHI 1981 (5) 831 - 835 0369-4577 1981 Scientific journal 
    Lewis acid (BF3∗OEt2) mediated allylation of methoxy-p-benzoquinone [5] with trans-cin-namyltrimethyltin at low temperature and successive mild oxidation gives -4-methoxydal-bergione [3] an antibiotic, in high regioselectivity (77%) and good yield. The reaction system posesses the possibility of forming six regioisomers, and the present synthetic method is the first successful example for the synthesis of [3] from the corresponding quinone Other Lewis acids (SnCl4, A1C18) were ineffective for the reaction both in regioselectivity and in yield. The amount of BF3OEt2slightly affected the regioselectivity and the best selectivity was obtained when three equivalent of BFaOEt2was used. The selective coordination of BFa.OEt2to MeO group of the quinone is proposed for the explanation of the high selectivity. This method is suggested to be promising for the synthesis of important intermediates of versatile bioactive quinones. © 1981, The Chemical Society of Japan. All rights reserved.
  • Y NARUTA, H UNO, K MARUYAMA
    TETRAHEDRON LETTERS 22 (51) 5221 - 5224 0040-4039 1981 Scientific journal 
    Allyltrimethylstannane reacts uith 2-alkanoyl-1,4-quinones regioselectively to afford conjugate addition products which can be derived to 2-alkanoyl- 3-allylhydroquinone diacetate, while allyltriphenylsilane reacts with the quinone to give naphthofuran. © 1981.

Books etc

Conference Activities & Talks

  • 松崎悠也, 志田陽一, 森重樹, 高瀬雅祥, 宇野英満, 奥島鉄雄
    複素環化学討論会講演要旨集  2015/11
  • シクロ[8]ピロールホスホン酸塩の合成と物性  [Not invited]
    松本宏樹, 森重樹, 高瀬雅祥, 宇野英満, 奥島鉄雄
    基礎有機化学討論会要旨集  2015/09
  • ベンゾポルフィリン希土類金属錯体の合成  [Not invited]
    小林朋広, 森重樹, 奥島鉄雄, 高瀬雅祥, 宇野英満
    基礎有機化学討論会要旨集  2015/09
  • ポルフィリン‐ヘキサピロロヘキサアザコロネン二量体の合成と物性  [Not invited]
    田川和成, 森重樹, 奥島鉄雄, 高瀬雅祥, 宇野英満
    基礎有機化学討論会要旨集  2015/09
  • ピロロ[3,4‐f]イソインドール骨格を有する二重N‐混乱ポルフィリノイドの合成と物性  [Not invited]
    平岡尚悟, 奥島鉄雄, 森重樹, 高瀬雅祥, 宇野英満
    基礎有機化学討論会要旨集  2015/09
  • 愛媛県産海綿動物由来の生物活性物質探索  [Not invited]
    坂本求, 倉本誠, 黒川嘉彦, 森重樹, 宇野英満
    日本化学会講演予稿集  2015/03
  • 構成分子の形状を利用したシクロファンの合成  [Not invited]
    沖光脩, 田川和成, 安藤千恵, 森重樹, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2015/03
  • 塩化金(I)触媒を用いたフェナセン型縮環芳香族化合物の合成  [Not invited]
    佐藤詩織, 森重樹, 奥島鉄雄, 宇野英満, 中江隆博
    日本化学会講演予稿集  2015/03
  • ヘキサピロロヘキサアザコロネンオリゴマーの合成と物性  [Not invited]
    田川和成, 安藤千恵, 沖光脩, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2015/03
  • アニオン交換によるシクロ[8]ピロールホスホン酸塩の合成  [Not invited]
    松本宏樹, 森重樹, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2015/03
  • ベンゾポルフィリンLa錯体の合成と物性評価  [Not invited]
    小林朋広, 森重樹, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2015/03
  • オキソカーボン酸とピロール誘導体の反応による近赤外色素の合成  [Not invited]
    上代一貴, 北束政波, 森重樹, 奥島鉄雄, 宇野英満, 増田豪, 青木正矩
    日本化学会講演予稿集  2015/03
  • ベンゾポルフィリンLa錯体の合成  [Not invited]
    小林朋広, 森重樹, 奥島鉄雄, 宇野英満
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • アニオン交換によるシクロ[8]ピロールホスホン酸塩の合成と物性  [Not invited]
    松本宏樹, 森重樹, 宇野英満, 奥島鉄雄
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • ベンゼン骨格を環状環状共役系に含む二重N‐混乱ポルフィリノイドの合成  [Not invited]
    平岡尚悟, 奥島鉄雄, 森重樹, 高瀬雅祥, 宇野英満
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • ジヨウ素化フェナセン型多環式芳香族化合物の合成  [Not invited]
    佐藤詩織, 森重樹, 奥島鉄雄, 宇野英満, 中江隆博
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • 愛媛県産海洋生物由来の生物活性物質の構造解析  [Not invited]
    坂本求, 黒川嘉彦, 倉本誠, 森重樹, 宇野英満
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • チオフェンを含む新規シクロ[9]ピロールの合成  [Not invited]
    小積遼平, 森重樹, 高瀬雅祥, 宇野英満, 奥島鉄雄
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • [7]ヘリセン誘導体の合成  [Not invited]
    谷本拓磨, 高瀬雅祥, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • 構成分子の立体を利用したシクロファンの合成と物性  [Not invited]
    沖光脩, 田川和成, 高瀬雅祥, 森重樹, 奥島鉄雄, 宇野英満
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • β連結型シクロ[n]ピロールの合成  [Not invited]
    日浦暢大, 志田陽一, 中村純, 森重樹, 高瀬雅祥, 宇野英満, 奥島鉄雄
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • ピロール誘導体とオキソカーボン酸の反応による近赤外色素の合成と物性  [Not invited]
    上代一貴, 北束政波, 森重樹, 高瀬雅祥, 奥島鉄雄, 宇野英満, 青木正矩
    日本分析化学会有機微量分析研究懇談会・計測自動制御学会力学量計測部会合同シンポジウム講演要旨集  2015
  • syn‐ジエタノアントラセン縮環ジピロール骨格を有するシクロファンの合成  [Not invited]
    沖光脩, 田川和成, 安藤千恵, 森重樹, 奥島鉄雄, 宇野英満
    有機典型元素化学討論会講演要旨集  2014/11
  • 近赤外発光を示すπ拡張O‐キレートBODIPYの合成と物性  [Not invited]
    志田陽一, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    有機典型元素化学討論会講演要旨集  2014/11
  • 新規テトラベンゾポルフィリン錯体の合成  [Not invited]
    三上晃寛, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    有機典型元素化学討論会講演要旨集  2014/11
  • BCOD架橋ジピロールとヘキサフルオロベンゼンを用いたシクロファンの合成  [Not invited]
    田川和成, 森重樹, 奥島鉄雄, 宇野英満
    基礎有機化学討論会要旨集  2014/08
  • 多置換アレーンの1,3‐ジブロモ‐5,5‐ジメチルヒダントイン(DBDMH)による臭素化反応の検討  [Not invited]
    金田知子, 森重樹, 谷弘幸, 宇野英満, 福田晃大, 江崎孝二
    日本プロセス化学会サマーシンポジウム講演要旨集  2014/07
  • meso位に電子求引性基を導入した共役拡張ポルフィリンの合成と物性  [Not invited]
    三浦志朗, 中村純, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2014/03
  • Diels‐Alder反応によるポルフィリンベータ位への置換基導入の検討  [Not invited]
    芳之内友子, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2014/03
  • アセン架橋ポルフィリンオリゴマーの合成と物性  [Not invited]
    田川和成, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2014/03
  • 逆Diels‐Alder反応を用いたベンゾサフィリンの合成  [Not invited]
    安倍俊樹, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2014/03
  • ベンゾおよびナフト縮環ビアズレン分子の合成と特性  [Not invited]
    中江隆博, 菊地貴志, 森重樹, 奥島鉄雄, 宇野英満, 村藤俊宏
    日本化学会講演予稿集  2014/03
  • キラルなナノπ空間を有するポルフィリン二量体とフラーレン類との錯形成能の評価  [Not invited]
    河本直樹, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2014/03
  • 新規な大環状化合物,2‐スルファニルヒドロキノン三量体の合成  [Not invited]
    渡邊竜介, 石川万莉, 宇野英満, 上村明男
    日本化学会講演予稿集  2014/03
  • 共役拡張型Aza‐BODIPY類の合成  [Not invited]
    志田陽一, 富盛祐也, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2014/03
  • スルファニルヒドロキノン二量体を用いたジベンゾフランの合成  [Not invited]
    石川万莉, 渡邊竜介, 宇野英満, 上村明男
    日本化学会講演予稿集  2014/03
  • β‐アルキル置換シクロ[n]ピロールの合成  [Not invited]
    松本宏樹, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2014/03
  • ビシクロ[2.2.2]オクタジエン骨格を有するベンゾチオフェン前駆体の合成と応用  [Not invited]
    宮井裕紀, 森重樹, 谷弘幸, 宇野英満
    日本化学会講演予稿集  2014/03
  • 多置換アレーンの1,3‐ジブロモ‐5,5‐ジメチルヒダントイン(DBDMH)による臭素化反応の検討  [Not invited]
    金田知子, 砂田亮, 森重樹, 谷弘幸, 宇野英満, 福田晃大, 江崎孝二
    日本化学会講演予稿集  2014/03
  • 塩化金触媒をもちいる環化反応を利用した[5]ヘリセン類縁体の合成  [Not invited]
    中江隆博, 北畑吉晴, 森重樹, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2014/03
  • 大環状構造を有するスルファニルヒドロキノンジメチルエーテルオリゴマーの合成  [Not invited]
    渡邊竜介, 石川万莉, 那須浩太郎, 宇野英満, 上村明男
    有機典型元素化学討論会講演要旨集  2013/12
  • スルファニルヒドロキノン二量体を使った新しい水溶性の蛍光染料の創成  [Not invited]
    野首智美, 渡邊竜介, 那須浩太郎, 石川万莉, 宇野英満, 上村明男
    有機典型元素化学討論会講演要旨集  2013/12
  • キラルなナノπ空間を有するポルフィリン二量体による包接錯体の形成  [Not invited]
    河本直樹, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    錯体化学会討論会講演要旨集  2013/10
  • ベンゾサフィリンの合成  [Not invited]
    安倍俊樹, 中村純, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    複素環化学討論会講演要旨集  2013/10
  • ピロロ[2,3‐f]インドール類の合成とその反応  [Not invited]
    芳野真己, 森重樹, 中江隆博, 奥島鉄雄, 青木正矩, 増田豪, 宇野英満
    複素環化学討論会講演要旨集  2013/10
  • メソイオン性オキサゾールの2‐ピラジノンへの環変換反応  [Not invited]
    西條亮介, 栗原健一, 河瀬雅美, 宇野英満
    複素環化学討論会講演要旨集  2013/10
  • 周辺部にフェニル基を有するテトラベンゾポルフィリンの合成  [Not invited]
    三上晃寛, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    有機合成化学セミナー講演予稿集  2013/09
  • チアポルフィリンにおけるプロトン化の挙動  [Not invited]
    田川和成, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    有機合成化学セミナー講演予稿集  2013/09
  • 近赤外光を吸収するO‐キレートBODIPYの光物性  [Not invited]
    志田陽一, 富盛祐也, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    光化学討論会講演要旨集  2013/09
  • ベンゼン架橋されたbisBODIPY色素を組み込んだ近赤外色素の光物性  [Not invited]
    北束政波, 中江隆博, 森重樹, 奥島鉄雄, 宇野英満
    光化学討論会講演要旨集  2013/09
  • 2,2’‐ビアズレン拡張T字型分子の合成  [Not invited]
    菊地貴志, 中江隆博, 森重樹, 奥島鉄雄, 村藤俊宏, 宇野英満
    基礎有機化学討論会要旨集  2013/08
  • 共役拡張bisBODIPY色素の合成とその物性  [Not invited]
    北束政波, 中江隆博, 森重樹, 奥島鉄雄, 宇野英満
    基礎有機化学討論会要旨集  2013/08
  • Diels‐Alder反応を利用したβ位連結ポルフィリンオリゴマーの合成検討  [Not invited]
    芳之内友子, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    基礎有機化学討論会要旨集  2013/08
  • 白金テトラベンゾポルフィリンの合成と物性  [Not invited]
    古田智哉, 橋本祐介, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    基礎有機化学討論会要旨集  2013/08
  • 共役拡張型O‐キレートBODIPYの合成と物性  [Not invited]
    志田陽一, 富盛祐也, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    基礎有機化学討論会要旨集  2013/08
  • 熱変換可能な可溶性前駆体を用いたフタロシアニンおよびテトラベンゾポルフィリンの合成  [Not invited]
    奥島鉄雄, 古田智哉, 橋本祐介, JIN Guangnan, 森重樹, 中江隆博, 山田容子, 小野昇, 宇野英満
    基礎有機化学討論会要旨集  2013/08
  • 二環性骨格を持った新規ポルフィリン二量体の合成  [Not invited]
    山本翔吾, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2013/03
  • トリプルデッカー型モノベンゾポルフィリン金属錯体の合成と物性  [Not invited]
    渡部祐大, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2013/03
  • 共役拡張bisBODIPYの合成とその近赤外色素としての物性  [Not invited]
    北束政波, 中村光則, 中江隆博, 森重樹, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2013/03
  • キラルな連結部位を有するポルフィリン二量体の合成  [Not invited]
    河本直樹, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2013/03
  • B,O‐キレート型ジピロメテンホウ素錯体の合成  [Not invited]
    志田陽一, 富森裕也, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2013/03
  • 塩化金(I)触媒を用いたハロゲン化フェナセン類の合成  [Not invited]
    北畑吉晴, 大西竜二, 中江隆博, 森重樹, 奥島鉄雄, 宇野英満, 坂口浩司
    日本化学会講演予稿集  2013/03
  • ビシクロ[2.2.2]オクタジエン骨格を有する新規チオフェン誘導体の合成  [Not invited]
    宮井裕紀, 那佐翔太, 森重樹, 谷弘幸, 宇野英満
    日本化学会講演予稿集  2013/03
  • 愛媛県産海綿動物由来の含窒素化合物の探索  [Not invited]
    黒川嘉彦, 倉本誠, 横尾義貴, 森重樹, 宇野英満
    日本化学会講演予稿集  2013/03
  • ビシクロ[2.2.2]オクタジエン骨格で連結したπ共役拡張型ポルフィリンオリゴマーの合成検討  [Not invited]
    芳之内友子, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2013/03
  • フェノチアジン及びアントラセンを架橋基とする新規環状ポルフィリン二量体の合成とフラーレンの包接  [Not invited]
    坂口健一, 上村拓也, 信国浩文, 石田真敏, 成田吉徳, 宇野英満, 谷文都
    日本化学会講演予稿集  2013/03
  • テトラブロモビアズレンのビスアリール化反応および環化反応の検討  [Not invited]
    菊地貴志, 中江隆博, 森重樹, 奥島鉄雄, 宇野英満, 村藤俊宏
    日本化学会講演予稿集  2013/03
  • キラルグラフェンナノリボン構造モチーフ分子の合成  [Not invited]
    杉村卓哉, 矢野真葵, 中江隆博, 森重樹, 奥島鉄雄, 宇野英満, 坂口浩司
    日本化学会講演予稿集  2013/03
  • 周辺部に置換基を有するテトラベンゾポルフィリンの合成  [Not invited]
    三上晃寛, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2013/03
  • 構造解析技術の向上による新機能性物質の探索と創出の加速  [Not invited]
    宇野英満, 谷弘幸, 倉本誠, 森重樹, 伊藤智志, 上村明男, 古田弘幸, 伊藤敏幸, 加藤知香, 北条正司, 馮旗, 高木由美子
    愛媛大学社会連携推進機構研究成果報告書  2013/03
  • ペリ環状反応を用いたナフトイソインドールの合成とその物性  [Not invited]
    清家彩, 長岡伸一, 中江隆博, 森重樹, 奥島鉄雄, 宇野英満
    複素環化学討論会講演要旨集  2012/09
  • ビス(フェナントロリノポルフィリン)の合成と物性  [Not invited]
    田中章仁, 中江隆博, 森重樹, 宇野英満, 奥島鉄雄
    複素環化学討論会講演要旨集  2012/09
  • BisBODIPY近赤外色素の合成とその電子状態の解明  [Not invited]
    中村光則, 高橋功太郎, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    基礎有機化学討論会要旨集  2012/09
  • ブタジイン架橋環状ポルフィリン二量体とPCBMからなる包接錯体の超分子構造  [Not invited]
    上村拓也, 信国浩文, 宇野英満, 島崎優一, 成田吉徳, 谷文都
    基礎有機化学討論会要旨集  2012/09
  • メゾアリール置換型ポルフィリンを用いたサンドイッチ型新奇金属錯体の合成  [Not invited]
    三木邦力, 森重樹, 奥島鉄雄, 中江隆博, 宇野英満
    基礎有機化学討論会要旨集  2012/09
  • p‐ターフェニルの連結によるオリゴフェニレン分子の合成と化学酸化による脱水素共役拡張  [Not invited]
    石岩大敦, 矢野真葵, 中江隆博, 森重樹, 奥島鉄雄, 宇野英満, 坂口浩司
    基礎有機化学討論会要旨集  2012/09
  • 多環式芳香族縮環シクロ[8]ピロールの合成と物性  [Not invited]
    安藤千恵, 松本直樹, 森重樹, 小原敬士, 中江隆博, 宇野英満, 奥島鉄雄
    基礎有機化学討論会要旨集  2012/09
  • 単核アルミニウムサイトに有機ジルコニウム種が配位した新規ポリオキソメタレートの分子構造と物性  [Not invited]
    牧野裕輝, 海野航, 宇野英満, 加藤知香
    錯体化学会討論会講演要旨集  2012/09
  • ジエタノアントラセンで架橋されたビスポルフィリンとフラーレンとの錯体形成挙動  [Not invited]
    田川和成, 渡部甫, 奥島鉄雄, 中江隆弘, 森重樹, 宇野英満
    日本化学会講演予稿集  2012/03
  • 塩化金触媒を用いた分子内四点環化反応によるハロゲン化縮環化合物の高効率合成及び誘導体の物性  [Not invited]
    大西竜二, 北畑吉晴, 中江隆博, 佐藤久子, 森重樹, 奥島鉄雄, 宇野英満, 坂口浩司
    日本化学会講演予稿集  2012/03
  • トリプルデッカー型ビスポルフィリン金属錯体の合成  [Not invited]
    渡部祐大, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2012/03
  • フタロシアニン前駆体の合成と物性  [Not invited]
    古田智哉, 橋本祐介, 森重樹, 中江隆博, 山田容子, 宇野英満, 小野昇, 奥島鉄雄
    日本化学会講演予稿集  2012/03
  • 塩化金(I)触媒を用いた多点環化反応による縮環芳香族の高収率合成  [Not invited]
    北畑吉晴, 大西竜二, 中江隆博, 佐藤久子, 森重樹, 奥島鉄雄, 宇野英満, 坂口浩司
    日本化学会講演予稿集  2012/03
  • メゾアリール置換型ポルフィリンを用いたサンドイッチ型新奇金属錯体の合成  [Not invited]
    三木邦力, 森重樹, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2012/03
  • ナフタレン縮環シクロ[8]ピロールの合成と物性  [Not invited]
    安藤千恵, 松本直樹, 小原敬士, 森重樹, 中江隆博, 山田容子, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2012/03
  • ブタジイン架橋環状ポルフィリン二量体とフラーレン類からなる包接錯体の超分子構造  [Not invited]
    上村拓也, 信国浩文, 宇野英満, 島崎優一, 成田吉徳, 谷文都
    日本化学会講演予稿集  2012/03
  • ナフタレン縮環イソインドール前駆体の合成とその熱または光による変換反応  [Not invited]
    清家彩, 山上薫, 中江隆博, 森重樹, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2012/03
  • ビスジピロメテンホウ素錯体の合成と物性の評価  [Not invited]
    中村光則, 高橋功太郎, 田原寛之, 永田央, 中江隆博, 奥島鉄雄, 宇野英満
    有機典型元素化学討論会講演要旨集  2011/12
  • 改良が進む近赤外発光材料 より広い用途への展開を目指して  [Not invited]
    宇野英満, 奥島鉄雄
    化学  2011/12
  • ベンゼン連結bisBODIPYの合成と物性  [Not invited]
    高橋功太郎, 田原寛之, 中村光則, 中江隆博, 奥島鉄雄, 宇野英満
    日本化学会西日本大会講演要旨集  2011/11
  • フェナントロリノピロールを配位子とするランタノイド金属錯体の合成  [Not invited]
    田中章仁, 三藤彰洋, 森重樹, 中江隆博, 山田容子, 宇野英満, 奥島鉄雄
    日本化学会西日本大会講演要旨集  2011/11
  • β位置換シクロ[8]ピロールの合成  [Not invited]
    松本直樹, 金光男, 安藤千恵, 森重樹, 中江隆博, 宇野英満, 奥島鉄雄
    日本化学会西日本大会講演要旨集  2011/11
  • ジホルミルイソチアナフテン6量体の合成と物性  [Not invited]
    宮本智行, 山田容子, 宇野英満, 奥島鉄雄
    複素環化学討論会講演要旨集  2011/09
  • 9,10‐アントラセンおよびアセナフチレン縮環シクロ[8]ピロールの合成と物性  [Not invited]
    安藤千恵, 松本直樹, 森重樹, 宇野英満, 小原敬士, 中江隆博, 奥島鉄雄
    基礎有機化学討論会要旨集  2011/09
  • ペンタセンジイミドの合成と物性  [Not invited]
    田中和樹, 勝田修平, 葛原大軌, 森重樹, 奥島鉄雄, 宇野英満, 山田容子
    基礎有機化学討論会要旨集  2011/09
  • [30]オクタフィリン(0.0.0.0.0.0.0.0)の合成と物性  [Not invited]
    奥島鉄雄, 松本直樹, 安藤千恵, 森重樹, JIN Guangnan, 山田容子, 中江隆博, 宇野英満
    基礎有機化学討論会要旨集  2011/09
  • 種々の縮環部位を有するメゾアリール置換型ポルフィリンの合成  [Not invited]
    三木邦力, 森重樹, 奥島鉄雄, 山田容子, 宇野英満
    基礎有機化学討論会要旨集  2011/09
  • ジ(1‐アズレニル)メチリウムユニットを有するポルフィリンの合成と物性  [Not invited]
    小林和史, 伊東俊司, 中江隆博, 山田容子, 宇野英満, 奥島鉄雄
    基礎有機化学討論会要旨集  2011/09
  • トリピランを用いた[14]トリフィリン(2.1.1)の合成と物性  [Not invited]
    葛原大軌, 榊原由佳, 森重樹, 奥島鉄雄, 宇野英満, 山田容子
    基礎有機化学討論会要旨集  2011/09
  • アセンビスイミドの合成と半導体特性  [Not invited]
    勝田修平, 田中和樹, 丸屋侑大, 森重樹, 増尾貞弘, 葛原大軌, 奥島鉄雄, 宇野英満, 中山健一, 山田容子
    基礎有機化学討論会要旨集  2011/09
  • チアトリフィリン類縁体の合成と物性  [Not invited]
    榊原由佳, 葛原大軌, 森重樹, 奥島鉄雄, 宇野英満, 山田容子
    基礎有機化学討論会要旨集  2011/09
  • 環状ポルフィリン二量体のフラーレンC70包接挙動  [Not invited]
    上村拓也, 信国浩文, 宇野英満, 島崎優一, 成田吉徳, 谷文都
    基礎有機化学討論会要旨集  2011/09
  • 5,14‐ペンタセンジケトンの合成と光物性  [Not invited]
    青竹達也, 山下裕子, 森重樹, 奥島鉄雄, 宇野英満, 山田容子
    光化学討論会講演要旨集  2011/09
  • Synthesis and Properties of Functional .PI.-Expanded Compounds Prepared by Thermal or Photochemical Conversion of the Precursors  [Not invited]
    山田容子, 葛原大軌, 勝田修平, 奥島鉄雄, 宇野英満
    有機合成化学協会誌  2011/07
  • 環状ポルフィリン二量体とC70からなるπ複合体の超分子構造  [Not invited]
    谷文都, 信国浩文, 宇野英満, 島崎優一, 上村拓也, 成田吉徳
    有機電子移動化学討論会講演要旨集  2011/06
  • 共役拡張オクタフィリンの合成と物性  [Not invited]
    安藤千恵, 松本直樹, JIN Guangnan, 葛原大軌, 森重樹, 山田容子, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2011/03
  • ベンゾ[1,2‐c;4,5‐c’]ジピロール前駆体の合成とその反応  [Not invited]
    田原寛之, 山上薫, 桑島未紀, 森重樹, 奥島鉄雄, 山田容子, 宇野英満
    日本化学会講演予稿集  2011/03
  • ラジカル環化を用いた光学活性なピロロスタノランの新規合成法  [Not invited]
    石川慎吾, 野口史昭, 宇野英満, 上村明男
    日本化学会講演予稿集  2011/03
  • B,O‐キレート型ジピロメテンホウ素錯体の合成と物性  [Not invited]
    奥島鉄雄, 富盛祐也, 矢野友子, 森重樹, 小野昇, 山田容子, 宇野英満
    日本化学会講演予稿集  2011/03
  • 電子吸引基を有するアセンの合成と物性  [Not invited]
    勝田修平, 宮城大地, 山田容子, 田中和樹, 奥島鉄雄, 森重樹, 中山健一, 宇野英満
    日本化学会講演予稿集  2011/03
  • β位で縮環したbis‐BODIPYの合成と物性  [Not invited]
    中村光則, 田原寛之, 魚山大樹, 山田容子, 森重樹, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2011/03
  • チオフェン骨格をもつトリフィリン類縁体の合成  [Not invited]
    榊原由佳, 葛原大軌, 宇野英満, 奥島鉄雄, 山田容子, 森重樹
    日本化学会講演予稿集  2011/03
  • ペンタセンビスイミドの合成と構造  [Not invited]
    田中和樹, 勝田修平, 山田容子, 奥島鉄雄, 森重樹, 宇野英満
    日本化学会講演予稿集  2011/03
  • メゾアリール置換型モノベンゾポルフィリンの合成  [Not invited]
    三木邦力, 森重樹, 奥島鉄雄, 山田容子, 宇野英満
    日本化学会講演予稿集  2011/03
  • 5,14‐ペンタセンジケトンの合成と光物性の比較  [Not invited]
    青竹達也, 山下裕子, 山田容子, 森重樹, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2011/03
  • ベンゼン架橋オリゴポルフィリンの合成と物性  [Not invited]
    魚山大樹, 奥島鉄雄, 山田容子, 宇野英満
    日本化学会講演予稿集  2011/03
  • ジホルミルイソチアナフテンオリゴマーの合成と物性  [Not invited]
    宮本智行, 奥島鉄雄, 山田容子, 宇野英満
    日本化学会講演予稿集  2011/03
  • 環状ポルフィリン二量体へのフラーレンC70の包接挙動  [Not invited]
    上村拓也, 信国浩文, 宇野英満, 島崎優一, 成田吉徳, 谷文都
    日本化学会講演予稿集  2011/03
  • [14]トリフィリン(2.1.1.)金属錯体の合成  [Not invited]
    葛原大軌, XUE ZhaoLi, 山田容子, 森重樹, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2011/03
  • 愛媛県産海綿動物由来の含窒素化合物の探索  [Not invited]
    横尾義貴, 倉本誠, 宇野英満
    日本化学会講演予稿集  2011/03
  • Synthesis Of pi-Expanded O-Chelated Boron?Dipyrromethene As An NIR Dye  [Not invited]
    ElsevierTetrahedron  2011
  • Ultrafast Intramolecular Energy Relaxation Dynamics of Benzoporphyrins: Influence of Fused Benzo Rings on Singlet Exited States  [Not invited]
    American Chemical SocietyJ. Phys. Chem. B  2011
  • Stellettazole D, a Cytotoxic Imidazole Alkaloid from the Marine Sponge Jaspis duoaster  [Not invited]
    日本化学会  2011
  • Identification of Geometrical Isomers Using Vibrational Circular Dichroism Spectroscopy: A Series of Mixed-Ligand Complexes of Diamagnetic Co(III) Ions  [Not invited]
    SATO Hisako, UNO Hidemitsu, NAKANO Haruyuki
    Dalton Transactions  2011
  • 混合配位子錯体の幾何異性に対する振動円二色性分光法による研究  [Not invited]
    佐藤久子, 宇野英満, 中野晴之, 山岸晧彦
    錯体化学討論会講演要旨集  2010/09
  • ナフトポルフィリン2量体の構造と物性  [Not invited]
    魚山大樹, 山田容子, 奥島鉄雄, 宇野英満
    複素環化学討論会講演要旨集  2010/09
  • ビシクロ[2.2.2]オクタジエン架橋ジピロールを用いた新規ポルフィリノイドの探索  [Not invited]
    田原寛之, 魚山大樹, 森重樹, 奥島鉄雄, 山田容子, 宇野英満
    複素環化学討論会講演要旨集  2010/09
  • 共役拡張ポルフィリン‐フラーレン付加体の合成と光ダイナミクス  [Not invited]
    葛原大軌, 大久保敬, 山田容子, 奥島鉄雄, 宇野英満, 福住俊一
    光化学討論会講演要旨集  2010/09
  • α‐ジケトン骨格を有するアセンモノマーユニットの合成  [Not invited]
    加藤竜太, 葛原大軌, 山田容子, 奥島鉄雄, 宇野英満
    光化学討論会講演要旨集  2010/09
  • 発光性ナフタセン誘導体の合成と光物性  [Not invited]
    青竹達也, 山田容子, 奥島鉄雄, 宇野英満
    光化学討論会講演要旨集  2010/09
  • McMurryカップリングを用いた[14]トリフィリン(2.1.1)の合成  [Not invited]
    葛原大軌, 山田容子, 森重樹, 奥島鉄雄, 宇野英満
    基礎有機化学討論会要旨集  2010/09
  • 官能基化アセン中間体として有用なジホルミルアセンの合成と物性  [Not invited]
    勝田修平, 山田容子, 奥島鉄雄, 森重樹, 宇野英満
    基礎有機化学討論会要旨集  2010/09
  • イソチアナフテンオリゴマーの合成と物性  [Not invited]
    宮本智行, 奥島鉄雄, 山田容子, 宇野英満
    基礎有機化学討論会要旨集  2010/09
  • ポルフィリン互変異性体の吸収および発光挙動  [Not invited]
    中村純, 奥島鉄雄, 小野昇, 細川清正, 鈴木健吾, 森重樹, 山田容子, 宇野英満, 小林長夫
    基礎有機化学討論会要旨集  2010/09
  • B,O‐キレート型ジピロメテンホウ素錯体の合成と物性  [Not invited]
    富盛祐也, 矢野友子, 森重樹, 山田容子, 宇野英満, 小野昇, 奥島鉄雄
    基礎有機化学討論会要旨集  2010/09
  • 環状ポルフィリン二量体のフラーレンC70包接  [Not invited]
    信国浩文, 谷文都, 島崎優一, 成田吉徳, 宇野英満
    基礎有機化学討論会要旨集  2010/09
  • フェナントロリノピロール‐ユウロピウム錯体の合成と物性  [Not invited]
    奥島鉄雄, 三藤彰洋, 大久保敬, 田中章仁, 山田容子, 宇野英満, 福住俊一
    配位化合物の光化学討論会講演要旨集  2010/08
  • 皮膚科受診患者の健康食品・サプリメント摂取調査  [Not invited]
    町野博, 倉本誠, 宇野英満
    皮膚病診療  2010/08
  • 振動円二色性分光法の混合配位子錯体への応用  [Not invited]
    佐藤久子, 宇野英満, 山岸皓彦
    シンポジウム「モレキュラー・キラリティー」講演要旨集  2010/07
  • フラーレン類を包接した環状ポルフィリン二量体の超分子構造とその光・電子物性  [Not invited]
    信国浩文, 谷文都, 島崎優一, 成田吉徳, 宇野英満, 大久保敬, 中西達昭, 小島隆彦, 福住俊一, 関修平
    日本化学会講演予稿集  2010/03
  • ビシクロ[2.2.2]オクタジエン縮環ピロールの分子内酸化カップリング反応を利用した高共役π電子系化合物の合成  [Not invited]
    魚山大樹, 滝上貴大, 増田豪, 宇野英満
    日本化学会講演予稿集  2010/03
  • 愛媛県産海洋生物由来の生物活性物質  [Not invited]
    横尾義貴, 三宅教道, 二宮高裕, 倉本誠, 宇野英満
    日本化学会講演予稿集  2010/03
  • 2,2’‐ビピロールを用いた拡張ポルフィリン類の合成  [Not invited]
    奥島鉄雄, JIN Guangnan, 葛原大軌, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2010/03
  • メソ置換型ポルフィセンの合成  [Not invited]
    葛原大軌, 矢野敬子, 奥島鉄雄, 山田容子, 宇野英満
    日本化学会講演予稿集  2010/03
  • α‐ジケトン前駆体の光反応を用いた置換テトラセンの合成と物性  [Not invited]
    青竹達也, 山田容子, 奥島鉄雄, 宇野英満
    日本化学会講演予稿集  2010/03
  • 共役拡張ペリレン系化合物の合成と物性  [Not invited]
    中村純, 小野昇, 山田容子, 宇野英満, 奥島鉄雄
    日本化学会講演予稿集  2010/03
  • 共役拡張アザピロメテン色素の合成と物性  [Not invited]
    富盛祐也, JIN Guangnan, 奥島鉄雄, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2010/03
  • ビシクロ[2,2,2]オクタジエン骨格を有するベンゾ‐1,4‐ジチイン誘導体の合成と性質  [Not invited]
    越智元気, 谷弘幸, 宇野英満
    日本化学会講演予稿集  2010/03
  • ビシクロ[2.2.2]オクタジエン環を組み込んだポルフィリノイドの合成と物性  [Not invited]
    田原寛之, 魚山大樹, 森重樹, 奥島鉄雄, 山田容子, 宇野英満
    日本化学会講演予稿集  2010/03
  • 可溶性前駆体からのフタロシアニン類の合成と塗布変換型OFET  [Not invited]
    奥島鉄雄, 橋本祐介, JIN Guangnan, 吉川侑, 中村純, 酒井良正, 大野玲, 大坪才華, 荒牧晋司, 山田容子, 宇野英満, 小野昇
    応用物理学関係連合講演会講演予稿集(CD-ROM)  2010/03
  • Preparation of highly conjugated oligoaza-PAHs based on the oxidative intramolecular coupling of bicyclo[2.2.2]octadiene-fused pyrrole  [Not invited]
    UNO Hidemitsu, TAKIUE Takahiro, UOYAMA Hiroki, OKUJIMA Tetsuo, YAMADA Hiroko, MASUDA Go
    Heterocycles  2010
  • Photophysical insights into supramolecular interaction of a designed bisporphyrin with fullerenes C60 and C70  [Not invited]
    PAL Debabrata, FURUKAWA Mina, KOMATSU Naoki, UNO Hidemitsu, BHATTACHARYA Sumanta
    ElsevierSpectrochim. Acta A  2010
  • Supramolecular Structures and Photoelectronic Properties of the Inclusion Complex of a Cyclic Free-Base Porphyrin Dimer and C60  [Not invited]
    NOBUKUNI Hirofumi, SHIMAZAKI Yuichi, UNO Hidemitsu, NARUTA Yoshinori, OHKUBO Kei, KOJIMA Takahiko, FUKUZUMI Shunichi, FUKUZUMI Shunichi, SEKI Shu, SEKI Shu, SAKAI Hayato, HASOBE Taku, TANI Fumito
    Wiley InetrscienceChem. Eur. J.  2010
  • Synthesis, Crystal Structure, and Photodynamics of π-Expanded Porphyrin−Fullerene Dyads Synthesized by Diels−Alder Reaction  [Not invited]
    YAMADA Hiroko, YAMADA Hiroko, OHKUBO Kei, KUZUHARA Daiki, TAKAHASHI Tetsuro, SANDANAYAKA Atula S. D, OKUJIMA Tetsuo, OHARA Keishi, ITO Osamu, UNO Hidemitsu, ONO Noboru, FUKUZUMI Shunichi, FUKUZUMI Shunichi
    American Chemical SocietyJ. Phys. Chem. B  2010
  • Pentacene precursors for solution-processed OFETs  [Not invited]
    UOYAMA Hiroki, YAMADA Hiroko, OKUJIMA Tetsuo, UNO Hidemitsu
    PergamonTetrahedron  2010
  • Intramolecular Pauson-Khand reaction of optically active axa-Baylis-Hillman adducts  [Not invited]
    ISHIKAWA Shingo, NOGUCHI Fumiaki, UNO Hidemitsu, KAMIMURA Akio
    PergamonTetrahedron Lett.  2010
  • Synthesis of 2,3-dihydrobenzo[1,4]dithiin-fused porphyrins  [Not invited]
    JIN Guangnan, OKUJIMA Tetsuo, HASHIMOTO Yusuke, YAMADA Hiroko, YAMADA Hiroko, UNO Hidemitsu, ONO Noboru
    Taylor and FrancisPhosphorus, Sulfur Silicon Relat. Elem.  2010
  • Protonation-Induced Formation of a Stable Singlet Biradicaloid Derived from a Modified Sapphyrin Analogue  [Not invited]
    WileyAngew. Chem. Int. Ed.  2010
  • Highly Pure Synthesis, Spectral Assignments, and Two-Photon Properties of Cruciform Porphyrin Pentamers Fused with Benzene Units  [Not invited]
    Wiley InterScienceChem. Eur. J.  2010
  • Thermal Behabior of Bicyclo[2.2.2]octadiene-Installed Precursors for 2H-Anthra[2,3-c]pyrroles and Anthra[2,3-c]thiophene  [Not invited]
    UOYAMA Hiroki, CAI Chenxin, CAI Chenxin, TAHARA Hiroyuki, SHIMIZU Yusuke, HAGIWARA Hideki, HANASAKI Yasuaki, YAMADA Hiroko, YAMADA Hiroko, OKUJIMA Tetsuo, UNO Hidemitsu, UNO Hidemitsu
    Institute of Heterocyclic ChemistryHeterocycles  2010
  • Synthesis and photochemical properties of α-diketoporphyrins as precursors for π-expanded porphyrins.  [Not invited]
    YAMADA Hiroko, YAMADA Hiroko, KUZUHARA Daiki, OHKUBO Kei, TAKAHASHI Tetsuro, OKUJIMA Tetsuo, UNO Hidemitsu, ONO Noboru, FUKUZUMI Shunichi, FUKUZUMI Shunichi
    J. Mater. Chem.  2010
  • Photochemical synthesis of tetraaryl-substituted pentacenes  [Not invited]
    KATSUTA Shuhei, YAMADA Hiroko, YAMADA Hiroko, OKUJIMA Tetsuo, UNO Hidemitsu
    Tetrahedron Lett.  2010
  • 光変換型ベンゾポルフィリン前駆体の合成と光反応  [Not invited]
    加藤竜太, 奥島鉄雄, 山田容子, 小野昇, 宇野英満
    日本化学会西日本大会講演要旨集  2009/11
  • 溶液法を用いた有機薄膜トランジスタ作成のためのペンタセン前駆体の熱及び光変換の研究  [Not invited]
    魚山大樹, 山田容子, 奥島鉄雄, 宇野英満
    日本化学会西日本大会講演要旨集  2009/11
  • 海洋生物に含まれる生体機能分子の探索  [Not invited]
    二宮高裕, 横尾義貴, 三宅教道, 倉本誠, 宇野英満
    日本化学会西日本大会講演要旨集  2009/11
  • ビシクロ[2.2.2]オクタジエン骨格を持つアザピロメテン色素の合成と物性  [Not invited]
    富盛祐也, 金光男, 宇野英満, 小野昇, 山田容子, 奥島鉄雄
    日本化学会西日本大会講演要旨集  2009/11
  • ベンゼン架橋十字型ポルフィリン5量体の合成と物性  [Not invited]
    魚山大樹, 永田央, 奥島鉄雄, 山田容子, 宇野英満
    日本化学会西日本大会講演要旨集  2009/11
  • ビシクロ[2.2.1]ヘプタジエン‐7‐オンのキレトロピー反応を用いた新規π電子系化合物の合成  [Not invited]
    桑島未紀, 垣谷兆政, 奥島鉄雄, 山田容子, 宇野英満
    日本化学会西日本大会講演要旨集  2009/11
  • ジ(1‐アズレニルメチリチウム)ユニットを有するポルフィリンの合成  [Not invited]
    小林和史, 吉川侑, 伊東俊司, 山田容子, 宇野英満, 奥島鉄雄
    日本化学会西日本大会講演要旨集  2009/11
  • 共生微生物由来の生物活性物質の探索  [Not invited]
    横尾義貴, 中島隼紀, 佐藤誠造, 倉本誠, 宇野英満
    日本化学会西日本大会講演要旨集  2009/11
  • ビシクロ骨格を有する1,4‐ジチイン誘導体の合成と性質  [Not invited]
    越智元気, 谷弘幸, 宇野英満
    日本化学会西日本大会講演要旨集  2009/11
  • ハロゲン化アリールの効率的なアミノ化反応の検討  [Not invited]
    岸本皇治, 横山未来, 谷弘幸, 宇野英満, 萩原秀樹, 田中亮宜, 花崎保彰
    日本化学会西日本大会講演要旨集  2009/11
  • 逆Diels‐Alder反応を利用した5,15‐ジアザテトラベンゾポルフィリンの合成と物性  [Not invited]
    金光男, 富盛祐也, 奥島鉄雄, 山田容子, 宇野英満, 小野昇
    日本化学会西日本大会講演要旨集  2009/11
  • フラーレン類を包接した環状ポルフィリン二量体の超分子構造とその光・電子物性  [Not invited]
    信国浩文, 谷文都, 島崎優一, 成田吉徳, 大久保敬, 中西達昭, 小島隆彦, 福住俊一, 関修平, 宇野英満
    基礎有機化学討論会要旨集  2009/09
  • 熱変換型前駆体を用いたフタロシアニン類の高純度合成  [Not invited]
    奥島鉄雄, JIN Guangnan, 吉川侑, 橋本祐介, 中村純, 山中梨津子, 山田容子, 宇野英満, 小野昇
    基礎有機化学討論会要旨集  2009/09
  • フェナントロリノピロールおよびその誘導体を用いたランタニド錯体の合成と光物性  [Not invited]
    三藤彰洋, 奥島鉄雄, 山田容子, 宇野英満
    光化学討論会講演要旨集  2009/09
  • 光変換型前駆体を利用した溶液塗布によるアセン薄膜の作成と伝導度特性の検討  [Not invited]
    山田容子, 橋詰純平, 河野裕郎, 楠貴博, 本庄義人, 関修平, 中山健一, 小野昇, 宇野英満
    光化学討論会講演要旨集  2009/09
  • 光反応を用いた置換ペンタセンの合成と物性  [Not invited]
    勝田修平, 山田容子, 宇野英満, 奥島鉄雄
    光化学討論会講演要旨集  2009/09
  • 溶液中におけるアセナフトポルフィリンの光物性(2)  [Not invited]
    中村純, 鈴木健吾, 細川清正, 山田容子, 宇野英満, 奥島鉄雄
    光化学討論会講演要旨集  2009/09
  • Synthesis and Properties of Benzoazuliporphyrins  [Not invited]
    吉川侑, 宇野英満, 小野昇, 山田容子, 奥島鉄雄
    日本化学会講演予稿集  2009/03
  • Synthesis of quinoxalinoporphyrins from their soluble precursors.  [Not invited]
    松本直樹, 菊池誠, 宇野英満, 小野昇, 山田容子, 奥島鉄雄
    日本化学会講演予稿集  2009/03
  • Photophysical Properties of acenaphthoporphyrins in solution  [Not invited]
    中村純, 小野昇, 宇野英満, 鈴木健吾, 山田容子, 奥島鉄雄
    日本化学会講演予稿集  2009/03
  • Synthesis and photochemical properties of diketone-linked porphyrins  [Not invited]
    山田容子, 村岸優, 葛原大軌, 宇野英満, 小野昇
    日本化学会講演予稿集  2009/03
  • Synthesis of bicyclo[2.2.2]octadiene-fused 1,4-dithiin derivatives by Ring-Expansion reaction.  [Not invited]
    越智元気, 小笠原崇, 谷弘幸, 宇野英満
    日本化学会講演予稿集  2009/03
  • Searching for bioactive compounds from symbiotic microorganisms  [Not invited]
    横尾義貴, 佐藤誠造, 倉本誠, 宇野英満
    日本化学会講演予稿集  2009/03
  • Synthesis of fluoranthene-fused boron-dipyrromethene dyes and their optical properties in the VIS-NIR region  [Not invited]
    富盛祐也, 宇野英満, 小野昇, 山田容子, 奥島鉄雄
    日本化学会講演予稿集  2009/03
  • Synthesis of bicyclo[2.2.2]octadiene-bridged hexaphyrin  [Not invited]
    魚山大樹, 滝上貴大, 宇野英満
    日本化学会講演予稿集  2009/03
  • Synthesis and luminescence behavior of rare earth complexes containing 1,10-phenanthroline ligands fused with porphyrins and pyrroles  [Not invited]
    三藤彰洋, 奥島鉄雄, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2009/03
  • Synthesis and FET-characteristics of phthalocyanine and benzoporphyrin derivatives by the solution process  [Not invited]
    奥島鉄雄, 橋本祐介, 大野玲, 酒井良正, 秋山誠治, 荒牧晋司, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2009/03
  • Synthesis and Properties of Benzothiophene Derivatives Involving Linear Alkyls in Both Ends  [Not invited]
    北野智也, 谷弘幸, 宇野英満
    日本化学会講演予稿集  2009/03
  • Structures of cylindradines from Axinella cylindratus  [Not invited]
    三宅教道, 倉本誠, 石丸恵久, 小野昇, 宇野英満
    日本化学会講演予稿集  2009/03
  • Synthesis and properties of meso-unsubtituted (fluoronaphtho)porphyrins  [Not invited]
    JIN Guangnan, 橋本祐介, 奥島鉄雄, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2009/03
  • Complexation between diethanoacene-fused diporphyrin and fullerenes  [Not invited]
    古川美奈, 橋本昌和, 小松直樹, 宇野英満
    日本化学会講演予稿集  2009/03
  • Synthesis and reaction of pyrroles fused with 7-tert-butoxybicyclo[2.2.1]heptadiene  [Not invited]
    宇野英満, 垣谷兆政
    日本化学会講演予稿集  2009/03
  • Chemo-enzymatic synthesis of spiro type gem-difluorocyclopropane as core molecule candidate for liquid crystal compounds  [Not invited]
    Wiley-VCHJ. Fluorine Chem.  2009
  • First Synthesis of meso-Chlorinated Tetrabenzoporphyrins  [Not invited]
    ITO Satoshi, PHONG Le Thanh, KOMATSU Takuya, IGARASHI Nagisa, OTSUBO Saika, SAKAI Yoshimasa, OHNO Akira, ARAMAKI Shinji, TANAKA Yousuke, UNO Hidemitsu, OBA Toru, HIRATANI Kazuhisa
    Wiley-VCHEur. J. Org. Chem.  2009
  • Stereoselective Synthesis of Bicyclic Nitrocyclopropanes by a Radical-Anion Domino Reaction  [Not invited]
    KAMIMURA Akio, KADOWAKI Ayako, YOSHIDA Takayuki, TAKEUCHI Ryota, UNO Hidemitsu
    Wiley-VCHChem. Eur. J.  2009
  • Pt(II) N-confused porphyrin: An expanded pyrrole that affords a stable pi-anion  [Not invited]
    Royal Chemical SocietyDalton Trans.  2009
  • Triply N-Confused Hexaphyrins: Near-Infrared Luminescent Dyes with a Triangular Shape  [Not invited]
    Wiley-VCHAngew. Chem. Int. Ed.  2009
  • 1-Aminoisoindole as a useful ?-system elongation unit  [Not invited]
    AKIYAMA Taiji, UOYAMA Hiroki, OKUJIMA Tetsuo, YAMADA Hiroko, YAMADA Hiroko, ONO Noboru, UNO Hidemitsu
    Elsevier  2009
  • Synthesis, Structures, and Optical and Electrochemical Properties of Benzoporphycenes  [Not invited]
    KUZUHARA Daiki, MACK John, YAMADA Hiroko, YAMADA Hiroko, OKUJIMA Tetsuo, ONO Noboru, KOBAYASHI Nagao
    Chem. Eur. J.  2009
  • First Synthesis of Porphyrin-Fused 1,10-Phenanthroline?Ruthenium(II) Complexes  [Not invited]
    OKUJIMA Tetsuo, MIFUJI Akihiro, NAKAMURA Jun, YAMADA Hiroko, YAMADA Hiroko, UNO Hidemitsu, ONO Noboru
    American Chemical SocietyOrg. Lett.  2009
  • アロエサポナリンIの紫外線防御と一重項酸素消去機能  [Not invited]
    日本ビタミン学会ビタミン  2009
  • Organic Thin-Film Transistor from a Pentacene Photo Precursor  [Not invited]
    Jpn J. Appl. Phys  2009
  • Synthesis, structures, and properties of BCOD-fused porphyrins and benzoporphyrins  [Not invited]
    UOYAMA Hiroki, TAKIUE Takahiro, TOMINAGA Kazuyuki, ONO Noboru, UNO Hidemitsu
    J. Porphyrins Phthalocyanines  2009
  • The Dakin-West reaction of n-acylprolines in the presence of inorganic bases: unexpected formation of enol esters  [Not invited]
    SAEKI Momoko, HAGIMOTO Yuri, UNO Hidemitsu, KAWASE Masami
    Heterocycles  2009
  • Synthesis and properties of benzene-fused diporphyrins with various metals  [Not invited]
    UNO Hidemitsu, HASHIMOTO Masakazu, FUJIMOTO Akiko
    Heterocycles  2009
  • テトラフルオロチアベンゾポルフィリン類の合成  [Not invited]
    古川美奈, 魚山大樹, 増田豪, 宇野英満
    フッ素化学討論会講演要旨集  2008/11
  • ニトロ基の特性を活かしたCalystegine類の合成的研究  [Not invited]
    鈴木秀三, 石川慎吾, 宇野英満, 上村明男
    日本化学会西日本大会講演要旨集  2008/11
  • .PI.-Expanded thioindigo precursors and their thermal behavior  [Not invited]
    西岡由維子, 宇野英満
    複素環化学討論会講演要旨集  2008/10
  • Synthesis and properties of F16 and F48 benzoporphyrins.  [Not invited]
    滝上貴大, 増田豪, 飯田俊也, 垣谷兆政, 宇野英満
    複素環化学討論会講演要旨集  2008/10
  • Synthesis and structural analysis of diporphyrins fused with cis and trans diethanotetracene  [Not invited]
    古川美奈, 藤本明子, 宇野英満
    複素環化学討論会講演要旨集  2008/10
  • A new stereoselective highly domino-cyclopropanation of nitro alkenes  [Not invited]
    吉田隆行, 竹内良太, 門脇亜矢子, 宇野英満, 上村明男
    複素環化学討論会講演要旨集  2008/10
  • Synthetic investigation of diporphyrins fused with diethanoanthracene for molecular recognition  [Not invited]
    橋本昌和, 宇野英満
    複素環化学討論会講演要旨集  2008/10
  • Structures and properties of bicyclo[2.2.2]octadiene- and benzene-fused oligoporphyrins  [Not invited]
    魚山大樹, 宇野英満
    複素環化学討論会講演要旨集  2008/10
  • 無置換ベンゾポルフィリン類の合成と構造  [Not invited]
    魚山大樹, 滝上貴大, 富永和孝, 小野昇, 宇野英満
    基礎有機化学討論会要旨集  2008/09
  • 分子エレクトロニクスの基盤技術―7 分子ドット  [Not invited]
    宇野英満
    機能材料  2008/04
  • 両端にフェニル基を有するチオフェン縮環‐1,2‐ジチインの合成と性質  [Not invited]
    越智元気, 大谷崇晃, 谷弘幸, 宇野英満, 小野昇
    日本化学会講演予稿集  2008/03
  • 可溶性前駆体を用いたテトラベンゾポルフィリンおよびフタロシアニン類の合成  [Not invited]
    奥島鉄雄, 橋本祐介, 小川大策, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2008/03
  • ジエタノアントラキノン架橋ポルフィリンダイマーの合成と構造  [Not invited]
    橋本昌和, 宇野英満
    日本化学会講演予稿集  2008/03
  • 愛媛県産海綿動物由来のフラノテルペン類の合成研究  [Not invited]
    高木貴浩, 稲葉正樹, 倉本誠, 宇野英満, 小野昇
    日本化学会講演予稿集  2008/03
  • チエノビス(ベンゾチオフェン)の合成と性質  [Not invited]
    大谷崇晃, 谷弘幸, 宇野英満, 小野昇
    日本化学会講演予稿集  2008/03
  • ビシクロ[2,2,2]オクタジエン骨格を組込んだポルフィリノイドの合成  [Not invited]
    滝上貴大, 宇野英満
    日本化学会講演予稿集  2008/03
  • ニトロアルカンの新規高度ドミノ反応用いたビシクロ[3.1.0]ヘキサンの立体選択的合成  [Not invited]
    吉田隆行, 門脇亜矢子, 宇野英満, 上村明男
    日本化学会講演予稿集  2008/03
  • ポルフィリン誘導体とオリゴチオフェンの反応  [Not invited]
    魚山大樹, 田中彰治, 宇野英満
    日本化学会講演予稿集  2008/03
  • 可溶性前駆体を用いたベンゾポルフィリン類の合成  [Not invited]
    橋本祐介, JIN Guangnan, 奥島鉄雄, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2008/03
  • ビスエタノテトラセン縮合ポルフィリンダイマーの合成と構造解析  [Not invited]
    古川美奈, 藤本明子, 宇野英満
    日本化学会講演予稿集  2008/03
  • プロリンの新規なDakin‐West反応:N‐アシル転位によるエノールの生成  [Not invited]
    佐伯もも子, 萩本有理, 河瀬雅美, 宇野英満
    日本薬学会年会要旨集  2008/03
  • スピロ‐ビス‐gem‐ジフルオロシクロプロパンのChemo‐enzymatic合成  [Not invited]
    伊藤敏幸, 菅原学, 中嶋紫野, 安倍良和, 早瀬修一, 川面基, 宮沢和利, 加藤孝, 宇野英満
    生体触媒化学シンポジウム講演要旨集  2008/01
  • Cylindradines A and B: Novel Bromopyrrole Alkaloids from Marine Sponge Axinella cylindratus  [Not invited]
    KURAMOTO Makoto, MIYAKE Norimichi, ISHIMARU Yoshihisa, ONO Noboru, UNO Hidemitsu
    Org. Lett.  2008
  • Stereoselective synthesis of azepines through the conjugate addition of formamides to nitroalkenes and subsequent intramolecular nitrile oxide cycloaddition reaction  [Not invited]
    KAMIMURA Akio, YOSHIDA Takayuki, UNO Hidemitsu
    Tetrahedron  2008
  • Doubly N-Fused Porphyrin  [Not invited]
    TOGANOH Motoki, KIMURA Tomoyuki, UNO Hidemitsu, FURUTA Hiroyuki
    Angew. Chem. Int. Ed.  2008
  • Preparation of 1,3,3a,7a-tetrahydroisothianaphthene and its application to tetrahydrothiophene-fused porphyrin  [Not invited]
    Heterocycles  2008
  • Near-Infrared Emission from Bis-PtII Complexes of Doubly N-Confused Calix[6]phyrins(1.1.1.1.1.1)  [Not invited]
    WON Dong‐Hoon, TOGANOH Motoki, TERADA Yosuke, FUKATSU Susumu, UNO Hidemitsu, FURUTA Hiroyuki
    Angew. Chem. Int. Ed.  2008
  • Synthesis and Characterization of Tetraanthroporphyrins  [Not invited]
    YAMADA Hiroko, YAMADA Hiroko, KUZUHARA Daiki, TAKAHASHI Tetsuro, SHIMIZU Yusuke, UOTA Keisuke, OKUJIMA Tetsuo, UNO Hidemitsu, ONO Noboru
    Org. Lett.  2008
  • Selective synthesis of 5-alkenyl-15-alkynyl-porphyrin and 5,15-dialkynyl-porphyrin by 2+2 acid-catalyzed condensation of dipyrrylmethane and TMS propynal  [Not invited]
    YAMADA Hiroko, YAMADA Hiroko, KUSHIBE Kayo, MITSUOGI Satoshi, OKUJIMA Tetsuo, UNO Hidemitsu, ONO Noboru
    Tetrahedron Lett.  2008
  • Linker-Oriented Design of Binaphthol Derivatives for Optical Resolution Using Lipase-Catalyzed Reaction  [Not invited]
    TANIGUCHI Tomohiro, FUKUBA Taka‐aki, NAKATSUKA Shuhei, HAYASE Shuichi, KAWATSURA Motoi, UNO Hidemitsu, ITOH Toshiyuki
    J. Org. Chem.  2008
  • Photophysical properties of a novel Ni(II)-diporphyrin in presence of fullerenes: Insights from experimental and theoretical studies  [Not invited]
    BHATTACHARYA Sumanta, HASHIMOTO Masakazu, FUJIMOTO Akiko, KIMURA Takahide, UNO Hidemitsu, KOMATSU Naoki
    Spectrochim. Acta, Part A  2008
  • 分子ドット  [Not invited]
    機能材料  2008
  • Soluble precursors of 2,3-naphthalocyanine and phthalocyanine for use in thin film transistors  [Not invited]
    HIRAO Atsuko, AKIYAMA Taiji, OKUJIMA Tetsuo, YAMADA Hiroko, YAMADA Hiroko, UNO Hidemitsu, SAKAI Yoshimasa, ARAMAKI Shinji, ONO Noboru
    The Royal Society of ChemistryChem. Commun.  2008
  • Application of MCD spectroscopy and TD-DFT to Nonplanar Core-Modified Tetrabenzoporphyrins: Effect of Reduced Symmetry on Nonplanar Porphyrinoids  [Not invited]
    MACK John, MACK John, BUNYA Masaru, SHIMIZU Yusuke, UOYAMA Hiroki, UOYAMA Hiroki, KOMOBUCHI Naoki, OKUJIMA Tetsuo, UNO Hidemitsu, UNO Hidemitsu, ITO Satoshi, STILLMAN Martin J, ONO Noboru, KOBAYASHI Nagao
    Wiley-VCHChem. Eur. J.  2008
  • Regioselective beta-Metalation of meso-Phosphanylporphyrins. Structure and Optical Properties of Porphyrin Dimers Linked by Peripherally Fused Phosphametallacycles  [Not invited]
    MATANO Yoshihiro, MATSUMOTO Kazuaki, NAKAO Yoshihide, UNO Hidemitsu, SAKAKI Shigeyoshi, IMAHORI Hiroshi
    American Chemical SocietyJ. Am. Chem. Soc.  2008
  • Thermal behavior of free-base and core-modified bicyclo[2.2.2]octadiene-fused porphyrins  [Not invited]
    UNO Hidemitsu, UNO Hidemitsu, SHIMIZU Yusuke, UOYAMA Hiroki, UOYAMA Hiroki, TANAKA Yousuke, TANAKA Yousuke, OKUJIMA Tetsuo, ONO Noboru
    WileyEur. J. Org. Chem.  2008
  • Synthesis of extremely soluble precursors of tetrabenzoporphyrins  [Not invited]
    OKUJIMA Tetsuo, HASHIMOTO Yusuke, JIN Guangnan, YAMADA Hiroko, YAMADA Hiroko, UNO Hidemitsu, ONO Noboru
    ELSEVIERTetrahedron  2008
  • 高共役π電子系化合物の高純度合成法の開発 平成17‐19年度  [Not invited]
    宇野英満
    高共役π電子系化合物の高純度合成法の開発 平成17-19年度 No.17350022  2008
  • 酸化銀/ヨウ素を用いたニトロアルカンの立体選択的新規ドミノシクロプロパン化反応  [Not invited]
    門脇亜矢子, 宇野英満, 上村明男
    有機典型元素化学討論会講演要旨集  2007/12
  • ビス(チエノベンゾ)‐1,2‐ジチイン及びチオフェンの合成とその物性  [Not invited]
    大谷崇晃, 石井尚志, 谷弘幸, 宇野英満, 小野昇
    有機典型元素化学討論会講演要旨集  2007/12
  • 南米産植物Huamanripaの成分研究  [Not invited]
    川井美貴子, 城戸雅裕, 谷弘幸, 高岡大輔, 宇野英満, 小野昇, 野崎浩
    日本化学会西日本大会講演要旨集  2007/11
  • 縮合多環型1,2‐ジチインおよびチオフェンの合成と性質  [Not invited]
    石井尚志, 大谷崇晃, 谷弘幸, 宇野英満, 小野昇
    日本化学会西日本大会講演要旨集  2007/11
  • 愛媛県産海洋生物由来の生物活性物質の探索  [Not invited]
    三宅教道, 倉本誠, 宇野英満
    日本化学会西日本大会講演要旨集  2007/11
  • 異種金属中心を持つビスポルフィリンの合成と物性  [Not invited]
    橋本昌和, 宇野英満
    日本化学会西日本大会講演要旨集  2007/11
  • 共役拡張チオインジゴの合成とその物性  [Not invited]
    西岡由維子, 宇野英満
    日本化学会西日本大会講演要旨集  2007/11
  • ビシクロ[2,2,2]オクタジエン縮環ポルフィリン類の熱的挙動  [Not invited]
    魚山大樹, 清水祐介, 田中洋輔, 奥島鉄雄, 宇野英満, 小野昇
    構造有機化学討論会講演予稿集  2007/10
  • スピロ‐ビス‐gem‐ジフルオロシクロプロパンのChemo‐enzymatic合成  [Not invited]
    伊藤敏幸, 菅原学, 中嶋紫野, 安倍良和, 早瀬修一, 川面基, 宮澤和利, 加藤孝, 宇野英満
    フッ素化学討論会講演要旨集  2007/10
  • フッ素化ベンゾ[c]複素5員環化合物の合成とその反応性  [Not invited]
    宇野英満, 吉田栄太, 築地真利江, 魚山大樹, 増田豪, 竹井一男
    フッ素化学討論会講演要旨集  2007/10
  • Synthesis and reaction of tetrafluorobenzo[c] pyrrole and thiophene  [Not invited]
    宇野英満, 新居資一郎, 築地真利江, 魚山大樹, 増田豪, 竹井一男
    複素環化学討論会講演要旨集  2007/09
  • 効率の良いアリールホモピペラジンの合成  [Not invited]
    横山未来, 谷弘幸, 宇野英満, 舘教智, 月田雅昭, 花崎保彰
    日本化学会講演予稿集  2007/03
  • 愛媛県産海洋生物由来の生物活性物質の探索  [Not invited]
    三宅教道, 石丸恵久, 倉本誠, 宇野英満, 小野昇
    日本化学会講演予稿集  2007/03
  • 新規可溶性前駆体を用いたテトラベンゾポルフィリンの合成と物性  [Not invited]
    橋本祐介, JIN Guangnan, 奥島鉄雄, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2007/03
  • Retro Diels‐Alder反応による可溶な前駆体からのフタロシアニン類の合成  [Not invited]
    平尾敦子, 小野昇, 宇野英満
    日本化学会講演予稿集  2007/03
  • フルオランテン縮環ベンゾポルフィリンの合成と物性  [Not invited]
    中村純, 奥島鉄雄, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2007/03
  • 単一分子デバイス作成に向けた分子ドット用ポルフィリンの合成  [Not invited]
    魚山大樹, CAI Chenxin, 宇野英満
    日本化学会講演予稿集  2007/03
  • フッ素化イソインドール合成法の開発研究  [Not invited]
    築地真利江, 増田豪, 飯田俊哉, 宇野英満
    日本化学会講演予稿集  2007/03
  • 制限された空孔を持つビシクロ[2.2.2]オクタジエン縮環ポルフィリンダイマーの合成  [Not invited]
    橋本昌和, 藤本明子, 宇野英満
    日本化学会講演予稿集  2007/03
  • ビシクロ[2.2.2]オクタトリエン縮環ピロールを用いたポルフィリン合成におけるretro‐Diels‐Alder反応  [Not invited]
    佐原由里, 宇野英満, 小野昇
    日本化学会講演予稿集  2007/03
  • ヘキサデカフルオロテトラベンゾポルフィリン類の合成  [Not invited]
    西岡由維子, 築地真利江, 増田豪, 飯田俊哉, 宇野英満
    日本化学会講演予稿集  2007/03
  • Synthesis of phthalocyanine fuzed with bicyclo[2.2.2]octadienes and thermal conversion into naphthalocyanine  [Not invited]
    Heterocycles  2007
  • Derivatization of tetrafluorobenzo[c]thiophene. Preparation of thiabenzoporphyrin  [Not invited]
    複素環研究所Heterocycles  2007
  • Stereoselective conjugated addition of lactams to nitroalkenes and formal total synthesis of indolizidine 167B  [Not invited]
    KAMIMURA Akio, NAGATA Yoshiaki, KADOWAKI Ayako, UCHIDA Kosuke, UNO Hidemitsu
    ElseierTetrahedron  2007
  • Retro-Diels-Alder reaction using bicyclo[2.2.2]octatriene-fused pyrrole during porphyrin synthesis  [Not invited]
    UNO Hidemitsu, UNO Hidemitsu, SAHARA Yuri, SAHARA Yuri, TAKIUE Takahiro, TAKIUE Takahiro
    ElsevierTetrahedron Lett.  2007
  • gem-Difluorocyclopropane as core molecule candidate for liquid crystal compounds  [Not invited]
    J. Fluorine Chem.  2007
  • Intravenous Infusion of Dihydroginsenoside Rb1 Prevents Compressive Spinal Cord Injury and Ischemic Brain Damage through Upregulation of VEGF and Bcl-XL  [Not invited]
    J. Neurotrauma  2007
  • Novel preparation of fluorinated isoindoles and their conversion to fluorinated benzoporphyrins  [Not invited]
    UNO Hidemitsu, MASUDA Go, TUKIJI Marie, NISHIOKA Yuiko, IIDA Toshiya
    ElsevierTetrahedron Lett.  2007
  • UV Protection and Singlet Oxygen Quenching Activity of Aloesaponarin I  [Not invited]
    NAGAOKA Shin‐ichi, FUJII Akiko, HINO Megumi, TAKEMOTO Mai, YASUDA Misaki, MISHIMA Mariko, OHARA Keishi, MASUMOTO Akane, UNO Hidemitsu, NAGASHIMA Umpei
    American Chemical SocietyJ. Phys. Chem. B  2007
  • Synthesis of porphyrin dimers fused with a benzene unit  [Not invited]
    UNO Hidemitsu, NAKAMOTO Ken‐ichi, KUROKI Kenji, FUJIMOTO Akiko, ONO Noboru
    Wiley-VCHChem. Eur. J.  2007
  • Preparation of Biphenylene- and Benzocyclooctene-fused Heterocycles  [Not invited]
    The Japan Institute of Heterocyclic ChemistryHeterocycles  2007
  • Benzene Ring Trimer Interactions Modulate Supramolecular Structures  [Not invited]
    MORIMOTO Tatsuki, UNO Hidemitsu, FURUTA Hiroyuki, FURUTA Hiroyuki
    Wiley-VCHAngew. Chem. Int. Ed.  2007
  • Stereoselective intramolecular 1,3-dipolar nitrile oxide cycloaddition reaction of N-formyl-β-nitroamides  [Not invited]
    KADOWAKI Ayako, NAGATA Yoshiaki, UNO Hidemitsu, KAMIMURA Akio
    PergamonTetrahedron Lett.  2007
  • Ruthenium-catalyzed Linear-selective Allylic Alkylation of Allyl Acetates  [Not invited]
    KAWATSURA Motoi, ATA Fumio, WADA Shohei, HAYASE Shuichi, UNO Hidemitsu, ITOH Toshiyuki
    Royal Society of ChemistryChem. Commun.  2007
  • A new metalloporphyrin dimer: Effective and selective molecular tweezers for fullerenes  [Not invited]
    BHATTACHARYA Sumanta, TOMINAGA Kazuyuki, KIMURA Takahide, UNO Hidemitsu, KOMATSU Naoki
    ElsevierChem. Phys. Lett.  2007
  • Diels‐Alder反応によるポルフィリン‐フラーレン化合物の合成と結晶構造  [Not invited]
    高橋哲郎, 山田容子, 奥島鉄雄, 宇野英満, 小野昇
    有機結晶部会ニュースレター  2006/11
  • テトラフルオロイソインドールの新規合成法  [Not invited]
    宇野英満, 築地真利江, 西岡由維子, 増田豪, 飯田俊哉
    フッ素化学討論会講演要旨集  2006/11
  • Synthesis and Properties of Benzocyclobutadienoquinazoline  [Not invited]
    魚山大樹, 宇野英満, 小野昇
    複素環化学討論会講演要旨集  2006/11
  • 共役拡張アズリポルフィリンの合成と物性  [Not invited]
    奥島鉄雄, 久保田浩, 中村純, 大石章博, 山田容子, 宇野英満, 小野昇
    基礎有機化学連合討論会予稿集  2006/10
  • ビシクロ[2.2.2]オクタジエン融合ポルフィリントリマーの逆Diels‐Alder反応  [Not invited]
    藤本明子, 宇野英満
    基礎有機化学連合討論会予稿集  2006/10
  • 新規ポルフィリン‐フラーレン化合物の合成と分子内電子移動反応  [Not invited]
    高橋哲郎, 山田容子, SANDANAYAKA Atula, 伊藤攻, 大久保敬, 福住俊一, 宇野英満, 小野昇
    基礎有機化学連合討論会予稿集  2006/10
  • Isolation and Structure Elucidation of Cytotoxic Compounds from Marine Sponge  [Not invited]
    中鋪愛, 佐藤誠造, 倉本誠, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • Synthesis of pyrroloisoxazoles via Michael addition/1,3-dipolar cycloaddition of formamides to nitroalkenes  [Not invited]
    門脇亜矢子, 永田義明, 宇野英満, 上村明男
    日本化学会講演予稿集  2006/03
  • A synthesis of phthalocyanines fused with bicycle[2,2,2]octadiene  [Not invited]
    平尾敦子, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • Conformational analyses of ortho-substituted 1,5-diarylvinamidines  [Not invited]
    鈴川博之, 宇野英満, 上村明男
    日本化学会講演予稿集  2006/03
  • Synthesis and reactions of 2-nitrobiphenylene  [Not invited]
    魚山大樹, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • Synthetic study of a triptycene-type tripyrrole.  [Not invited]
    佐原由里, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • Selective synthesis of 5-alkenyl-15-alkynyl-benzoporphyrins and a development to butadiyne dimer  [Not invited]
    櫛部加代, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • The synthesis of soluble precursor of .PI.-conjugated compound derivatives  [Not invited]
    坂本定章, 河村恵美, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • Structures of Novel Phakellins from Marine Sponge  [Not invited]
    石丸恵久, 倉本誠, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • Heterocyclic synthesis through Michael addition of alicyclic amides to nitroalkenes  [Not invited]
    永田義明, 門脇亜矢子, 宇野英満, 上村明男
    日本化学会講演予稿集  2006/03
  • Synthesis of Conjugation-expanded Azuliporphyrin Derivatives  [Not invited]
    久保田浩, 奥島鉄雄, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • The structure elucidation of furanoterpenes from the marine sponge  [Not invited]
    稲葉正樹, 倉本誠, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • Synsthesis of new .PI.-conjugated compounds containing isothianaphtene  [Not invited]
    神田真太郎, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • Synthesis of Tetrafluoroisothianaphthene derivatives  [Not invited]
    築地真利江, 宇野英満
    日本化学会講演予稿集  2006/03
  • Interaction between Vinamidine-crown hybrid compound and 1,n-diammonium salt  [Not invited]
    松山敬満, 宇野英満, 上村明男
    日本化学会講演予稿集  2006/03
  • Synthesis and Properties of Porphyrin Dimers with Various Center Metals  [Not invited]
    藤本明子, 宇野英満, 小野昇
    日本化学会講演予稿集  2006/03
  • Synthesis of 4,7-Dihydro-2H-isoindole Derivatives via Diels-Alder Reaction of Tosylacetylene  [Not invited]
    The Japan Institute of Heterocyclic ChemistryHeterocycles  2006
  • A New Synthesis of Tetra(quinoxalino)tetraazaporphyrin by retro Diels-Alder Reaction of a Soluble Precursor  [Not invited]
    Society of Porphyrins and PhthalocyaninesJ. Porphyrins Phthalocyanines  2006
  • Effective photochemical synthesis of an air-stable anthracene-based organic semiconductor from its diketone precursor  [Not invited]
    YAMADA Hiroko, KAWAMURA Emi, SAKAMOTO Sadaaki, YAMASHITA Yuko, OKUJIMA Tetsuo, UNO Hidemitsu, ONO Noboru
    Tetrahedoron Letters  2006
  • Formamide as an Efficient Nitrogen Nucleophile for the Michael Addition to Nitoalkenes  [Not invited]
    KAMIMURA Akio, KADOWAKI Ayako, NAGATA Yoshiaki, UNO Hidemitsu
    ElsevierTetrahedron Lett.  2006
  • A New Synthesis of Acenaphthobenzoporphyrin and Fluoranthobenzoporphyrin  [Not invited]
    The Japan Institute of Heterocyclic ChemistryHeterocycles  2006
  • Novel one-pot synthesis of 5-alkenyl-15-alkynylporphyrins and their derivatization to a butadiyne-linked benzoporphyrin dimer  [Not invited]
    YAMADA Hiroko, KUSHIBE Kayo, OKUJIMA Tetsuo, UNO Hidemitsu, UNO Hidemitsu, ONO Noboru
    The Royal Society of ChemistryChem. Commun.  2006
  • イソチアナフテンオリゴマーの合成と機能  [Not invited]
    渡辺達央, 清水祐介, 宇野英満, 小野昇
    ヘテロ原子化学討論会講演要旨集  2005/12
  • 2―ニトロビフェニレンの合成と反応  [Not invited]
    魚山大樹, 宇野英満, 小野昇
    日本化学会西日本大会講演予稿集  2005/10
  • 1,5‐ジアリールビナミジンの機能化に向けたコンホメーション解析  [Not invited]
    鈴川博之, 永田義明, 宇野英満, 上村明男
    日本化学会西日本大会講演予稿集  2005/10
  • イソチアナフテン誘導体の合成と反応  [Not invited]
    築地真利江, 清水祐介, 宇野英満, 小野昇
    日本化学会西日本大会講演予稿集  2005/10
  • ニトロアルケンへのアミド求核剤のマイケル付加反応  [Not invited]
    永田義明, 門脇亜矢子, 宇野英満, 上村明男
    日本化学会西日本大会講演予稿集  2005/10
  • Synthesis of Benzosapphyrin  [Not invited]
    川上沙織, 清水祐介, 宇野英満, 小野昇
    複素環化学討論会講演要旨集  2005/10
  • Syntheses of doubly N-fused-hexabenzohexaphyrin and tetrabenzo(triply linked porphyrin dimer) via retro Diels-Alder reaction and their properties  [Not invited]
    猪熊泰英, 小野昇, 宇野英満, 大須賀篤弘
    複素環化学討論会講演要旨集  2005/10
  • Stereoselective Michael addition of amide nucleophiles to nitroalkenes  [Not invited]
    門脇亜矢子, 永田義明, 宇野英満, 上村明男
    複素環化学討論会講演要旨集  2005/10
  • 発光分光法とab initio分子軌道計算を用いたアロエサポナリンの励起状態の研究  [Not invited]
    竹本真唯, 日野めぐみ, 桝本茜, 宇野英満, 長嶋雲兵, 長岡伸一
    分子構造総合討論会講演要旨集(CD-ROM)  2005/09
  • 逆Diels‐Alder反応を利用した共役拡張型ポルフィリン類の合成  [Not invited]
    奥島鉄雄, 久保田浩, 中村純, 菰淵直樹, 宇野英満, 小野昇
    構造有機化学討論会講演予稿集  2005/08
  • 共役拡張ポルフィリンオリゴマーの構造と物性  [Not invited]
    藤本明子, 宇野英満, 小野昇
    構造有機化学討論会講演予稿集  2005/08
  • Synthesis of Benzosapphyrin Derivatives  [Not invited]
    川上沙織, 清水祐介, 宇野英満, 小野昇
    日本化学会講演予稿集  2005/03
  • Synthesis of a bicyclo[2.2.2]octatriene-fused pyrrole and its reactions  [Not invited]
    佐原由里, 宇野英満, 小野昇
    日本化学会講演予稿集  2005/03
  • Development of a specific synthesis of 5-alkenyl-15-alkynyl bicycloporphyrins  [Not invited]
    櫛部加代, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2005/03
  • The synthesis soluble precursors of pentacene  [Not invited]
    坂本定章, 宇野英満, 小野昇
    日本化学会講演予稿集  2005/03
  • Syntheses and properties of doubly N-fused-.BETA.-benzohexaphyrins  [Not invited]
    猪熊泰英, 大須賀篤弘, 小野昇, 宇野英満
    日本化学会講演予稿集  2005/03
  • Stereoselective Michael addition of amide nucleophiles to nitroalkenes  [Not invited]
    永田義明, 門脇亜矢子, 宇野英満, 上村明男
    日本化学会講演予稿集  2005/03
  • Study on the introduction of an amino group to the pyrrole ring fused with bicyclo[2.2.2]octadiene  [Not invited]
    田中洋輔, 宇野英満, 小野昇
    日本化学会講演予稿集  2005/03
  • Synthesis of highly pure .PI.-system-fused porphyrin oligomers  [Not invited]
    藤本明子, 宇野英満, 小野昇
    日本化学会講演予稿集  2005/03
  • Synthesis of novel .PI.-expanded isothianaphthene derivatives terminated with electron-withdrawing groups  [Not invited]
    渡辺達央, 清水祐介, 宇野英満, 小野昇
    日本化学会講演予稿集  2005/03
  • Synthesis, crystal structure and magnetic susceptibility of a novel binuclear complex: [Cu2(phen)2(4,4′-dpy)3(OH)2]?2NO3?5.5H2O  [Not invited]
    J. Coord. Chem.  2005
  • Enlarged pi-Electronic Network of a meso-meso, beta-beta, beta-beta Triply Linked Dibenzoporphyrin Dimer that Exhibits a Large Two-electron Absorption Cross Section  [Not invited]
    INOKUMA Yasuhide, INOKUMA Yasuhide, ONO Noboru, UNO Hidemitsu, KIM Deok Yun, NOH Soo Bum, KIM Dongho, OSUKA Atsuhiro, OSUKA Atsuhiro
    Royal Society of Chemistry  2005
  • Photochemical Synthesis of Pentacene and its Derivatives  [Not invited]
    YAMADA Hiroko, YAMASHITA Yuko, KIKUCHI Makoto, WATANABE Hikaru, OKUJIMA Tetsuo, UNO Hidemitsu, UNO Hidemitsu, OGAWA Takuji, OHARA Keishi, ONO Noboru
    Wiley-VCHChem. Eur. J.  2005
  • Photo precursor for pentacene  [Not invited]
    UNO H, YAMASHITA Y, KIKUCHI M, WATANABE H, YAMADA H, OKUJIMA T, OGAWA T, ONO N
    ELSEVIERTetrahedron Lett.  2005
  • A Doubly N-Fused Benzohexaphyrin and Its Rearrangement to a Fluorescent Macrocycle Containing Two Indol[[2,1-a]isoquinolin-5-one Subunits Upon DDQ Oxidation  [Not invited]
    INOKUMA Yasuhide, MATSUNARI Takahiro, ONO Noboru, UNO Hidemitsu, OSUKA Atsuhiro
    Angew. Chem. Int. Ed.  2005
  • Extremely large cavity assembled by self-interlocking of distorted biconcave porphyrins  [Not invited]
    UNO H, WATANABE H, YAMASHITA Y, ONO N
    Royal Society of ChemistryOrg. Biomol. Chem.  2005
  • Synthesis of Water-soluble Porphyrin and the Corresponding Highly Planar Benzoporphyrin without meso-Substituents  [Not invited]
    MURASHIMA T, TSUJIMOTO S, YAMADA T, MIYAZAWA T, UNO H, ONO N, SUGIMOTO N
    Tetrahedron Lett.  2005
  • Kinetic Study of the Mechanism of Free-Radical Scavenging Action in Curcumin: Effects of Solvent and pH  [Not invited]
    OHARA Keishi, MIZUKAMI Wataru, TOKUNAGA Aiko, NAGAOKA Shin‐ichi, UNO Hidemitsu, MUKAI Kazuo
    日本化学会  2005
  • 逆Diels‐Alder反応によるベンゾ[b]チオフェン誘導体の合成  [Not invited]
    岩品真悟, 石川貴之, 宇野英満, 小野昇
    ヘテロ原子化学討論会講演要旨集  2004/12
  • Synthesis of novel benzoporphyrin derivatives and their application  [Not invited]
    櫛部加代, SHEN Z, 山田容子, 宇野英満, 奥島鉄雄, 小野昇
    複素環化学討論会講演要旨集  2004/11
  • 含酸素複素環縮環生理活性キノン類の合成研究  [Not invited]
    村上誠也, 宇野英満, 藤本明子, 小野昇
    日本化学会西日本大会講演予稿集  2004/10
  • ビシクロ[2.2.2]オクタジエン縮環トリピランを用いた共役拡張型ポルフィリン類の合成  [Not invited]
    菰淵直樹, 清水祐介, 奥島鉄雄, 宇野英満, 小野昇
    基礎有機化学連合討論会予稿集  2004/09
  • 逆Diels‐Alder反応を利用した共役拡張型ヘテロポルフィリン類の合成  [Not invited]
    奥島鉄雄, 菰淵直樹, 清水祐介, 宇野英満, 小野昇
    基礎有機化学連合討論会予稿集  2004/09
  • アロエサポナリンの光化学反応の研究  [Not invited]
    日野めぐみ, 竹本真唯, 倉光誠, 藤井亜紀子, 長岡伸一, 桝本茜, 宇野英満, 長嶋雲兵
    分子構造総合討論会講演要旨集(CD-ROM)  2004/09
  • Synthesis of meso-alkynyl substituted benzoporphyrins  [Not invited]
    櫛部加代, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • Synthesis of novel isothianapthene oligomers terminated with electron-withdrowing groups.  [Not invited]
    渡辺達央, 清水祐介, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • Solvent Dependence on Free-Radical Scavenging Activities of Curcumin and its Related Compounds  [Not invited]
    水上渉, 小原敬士, 徳永愛子, 向井和男, 宇野英満
    日本化学会講演予稿集  2004/03
  • Synthesis and properties of pi-extended Porphyrin  [Not invited]
    松成恭博, 荒谷直樹, 大須賀篤弘, 小野昇, 宇野英満
    日本化学会講演予稿集  2004/03
  • Synthesis of conjugation-expanded arenes with fused thiophene  [Not invited]
    岩品真悟, 小野昇, 宇野英満, 森山佳奈
    日本化学会講演予稿集  2004/03
  • A new synthesis of anthraporphyrin and their properties  [Not invited]
    魚田啓介, 山田容子, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • Synthesis and Property of Porphyrin Dimers Fused with Anthracene Bridge  [Not invited]
    富永和孝, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • Synthesis and Properties of Novel .PI.-expanded Azuliporphyrin  [Not invited]
    福上将正, 菰淵直樹, 奥島鉄雄, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • Synthesis properties of porphyrins with sulfur substituents  [Not invited]
    松本真吾, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • Synthesis and properties of benzosapphyrin.  [Not invited]
    川上沙織, 黒木健司, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • Synthesis of conjugated porphyrin derivatives using tripyrrane fused with bicyclo[2.2.2]octadiene rings  [Not invited]
    菰淵直樹, 奥島鉄雄, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • Synthesis of novel .PI.-expanded core-modified porphyrin derivatives  [Not invited]
    清水祐介, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • Synthesis of pyranoanthraquinone AH-1763IIa by utilizing intramolecular cyclization reactions  [Not invited]
    村上誠也, 宇野英満, 小野昇
    日本化学会講演予稿集  2004/03
  • A new synthesis of polyacenes  [Not invited]
    山下裕子, 小野昇, 宇野英満
    日本化学会講演予稿集  2004/03
  • Thioindigo Precursor: Control of Polymorph of Thioindigo  [Not invited]
    UNO H, MORIYAMA K, ISHIKAWA T, ONO N, YAHIRO H
    Tetrahedron Lett.  2004
  • Controlling Conformations and Physical Properties of meso-Tetrakis- (phenylethynyl)porphyrins by Ring Fusion: Synthesis, Properties and Structural Characterizations  [Not invited]
    SHEN Z, UNO H, SHIMIZU Y, ONO N
    Royal Society of ChemistryOrg. Biomol. Chem.  2004
  • Boro-Diindomethene (BDI) Dyes and Their Tetrahydrobicyclo Precursors?en Route to a New Class of Highly Emissive Fluorophores for the Red Spectral Range  [Not invited]
    SHEN Z, ROEHR H, RURACK K, UNO H, SPIELES M, SCHULZ B, RECK G, ONO N
    Chem. Eur. J.  2004
  • An Efficient Synthesis of Conjugation-expanded Carba- and Azuliporphyrins Using a Bicyclo[2.2.2]octadiene Fused Tripyrrane  [Not invited]
    OKUJIMA T, KOMOBUCHI N, SHIMIZU Y, UNO H, ONO N
    Tetrahedron Lett.  2004
  • First Synthesis of a Series of Core-modified Tetrabenzoporphyrins  [Not invited]
    SHIMIZU Y, SHEN Z, OKUJIMA T, UNO H, ONO N
    Royal Society of ChemistryChem. Comm.  2004
  • A New Synthesis of Mono- and Dibenzosapphyrins  [Not invited]
    Heterocycles  2004
  • Antifungal Activity of Organobismuth Compounds against the Yeast Saccharomyces cerevisiae: Structure Activity Relationship and Crystal Structure,  [Not invited]
    J. Inorg. Biochem.  2004
  • 超分子シントンを有するビスムタン類の会合構造  [Not invited]
    村藤俊宏, 藤本直樹, 三好洋平, 占部祐子, 杉原美一, 宇野英満
    ヘテロ原子化学討論会講演要旨集  2003/12
  • ベンゾチオフェン誘導体を用いた新規共役拡張分子の合成と物性  [Not invited]
    清水祐介, 奥島鉄雄, 宇野英満, 小野昇
    ヘテロ原子化学討論会講演要旨集  2003/12
  • β位にカルボキシル基を持つポルフィリンの合成と物性  [Not invited]
    西岡祐子, 宇野英満, 井上健太郎, 小野昇
    日本化学会西日本大会講演予稿集  2003/10
  • カリックス型ポルフィリン環の結晶構造: 積み重ねにより誘起されたポルフィリン環のゆがみ  [Not invited]
    宇野英満, 山下裕子, 渡辺光, 小野昇
    構造有機化学討論会講演予稿集  2003/10
  • ニトロニルニトロキシド基を有するアズレン類の合成,構造ならびに性質  [Not invited]
    三原聡, 黒飛敬, MUSTAFIZUR, R A F M, 薬師時里子, 村藤俊宏, 杉原美一, 宇野英満
    構造有機化学討論会講演予稿集  2003/10
  • 安定ラジカルで置換されたアズレン類の合成と構造,ならびに性質  [Not invited]
    三原聡, 黒飛敬, 薬師寺里子, 村藤俊宏, 杉原美一, 宇野英満
    有機反応化学討論会研究発表・講演予稿集  2003/09
  • 逆Diels-Alder反応を利用した共役拡張分子の合成  [Not invited]
    黒木健司, 桝本茜, 中元健一, 宇野英満, 小野昇
    有機反応化学討論会研究発表・講演予稿集  2003/09
  • アロエサポナリンの励起状態プロトン移動における節面モデル  [Not invited]
    長岡伸一, 藤井亜紀子, 倉光誠, 日野めぐみ, 桝本茜, 宇野英満, 長嶋雲兵
    分子構造総合討論会講演要旨集(CD-ROM)  2003/09
  • ネオリグナンであるmorinol C及びmorinol Dの光学活性体の合成  [Not invited]
    山内聡, 宇野英満
    日本農芸化学会大会講演要旨集  2003/03
  • Synthetic study of property-changeable functional dyes  [Not invited]
    森山佳奈, 宇野英満, 小野昇, 石川貴之
    日本化学会講演予稿集  2003/03
  • Synthesis and properties of novel isothianaphthene derivatives  [Not invited]
    清水祐介, 宇野英満, 小野昇
    日本化学会講演予稿集  2003/03
  • Syntheses and properties of octaalkoxyporphyrins and thier polymers  [Not invited]
    岩品真悟, 小野昇, 村嶋貴之, 宇野英満
    日本化学会講演予稿集  2003/03
  • Synthesis of Porphyrin Oligomers from Pyrrole-fused Porphyrins  [Not invited]
    黒木健司, 宇野英満, 小野昇
    日本化学会講演予稿集  2003/03
  • Synthesis of novel and soluble cyclic oligomer of pyrroles  [Not invited]
    秋山泰士, 宇野英満, 小野昇
    日本化学会講演予稿集  2003/03
  • Synthesis and Structure of Porphyrin Dimers Fused with Acene Bridges  [Not invited]
    宇野英満, 桝本茜, 小野昇
    日本化学会講演予稿集  2003/03
  • Synthetic study of Pyranoanthoraqinone AH-1763IIa  [Not invited]
    村上誠也, 宇野英満, 井門弓子, 小野昇
    日本化学会講演予稿集  2003/03
  • Synthesis of Tetrabenzoporphyrins by the Retro-Diels-Alder Reaction at Room Temperature  [Not invited]
    石川貴之, 星徹, 宇野英満, 小野昇
    日本化学会講演予稿集  2003/03
  • Synthesis of pentacene derivatives based on the retro-Diels-Alder reaction  [Not invited]
    山下裕子, 宇野英満, 小野昇
    日本化学会講演予稿集  2003/03
  • Synthesis and reaction of 5-membered heterocyclic compounds fused with a bicyclo[2.2.2]octadiene system.  [Not invited]
    勝山由来子, 宇野英満, 清水祐介, 小野昇
    日本化学会講演予稿集  2003/03
  • Synthesis of unsubstituted benzoporphyrin based on the retro Deils-Alder reactions.  [Not invited]
    富永和孝, 宇野英満, 黒木健司, 小野昇
    日本化学会講演予稿集  2003/03
  • A New Synthesis of Functional Dyes from 2-Acenaphtho[1,2-c]pyrrole  [Not invited]
    Heterocycles  2003
  • Oligocyclization of 2-(Hydroxymethyl)pyrroles with Electron-withdrawing Groups at beta-Positions: Formation and Structural Elucidation of Porphyrinogens and Hexaphyrinogens, "Jointly authored"  [Not invited]
    UNO H, INOUE K, INOUE T, ONO N
    Org. Biomol. Chem.  2003
  • Hexagonal Columnar Porphyrin Structure by Unique Trimeric Assembly of Porphyrin Dimer with pi-pi Stacking: Remarkable Thermal Behavior in a Solid, "Jointly authored"  [Not invited]
    UNO H, MASUMOTO A, ONO N
    J. Am. Chem. Soc.  2003
  • Soluble precursors convertible to tetrabenzoporphyrins below room temperature, "Jointly authored"  [Not invited]
    UNO H, ISHIKAWA T, HOSHI T, ONO N
    Tetrahedron Lett.  2003
  • Syntheses of the Stereoisomers of Neolignans Morinol C and D, "Jointly authored"  [Not invited]
    YAMAUCHI S, UNO H
    Org. Biomol. Chem.  2003
  • NMR and X-ray analyses of triethyl 3,7,11-triphenylcyclonona[1,2-b;4,5-b';7,8-b'']- tripyrrole-2,6,10-tricarboxylate: Reinvestigation of crown vs saddle conformation of cyclononatripyrroles,  [Not invited]
    UNO H, FUMOTO Y, INOUE K, ONO N
    Tetrahedron  2003
  • Synthesis of Porphyrin Oligomers from Pyrrole-fused Porphyrins.  [Not invited]
    黒木健司, 桝本茜, 宇野英満, 小野昇
    複素環化学討論会講演要旨集  2002/11
  • 深いキャビティーを有するポルフィリン類の合成と物性  [Not invited]
    宇野英満
    日本化学会西日本大会講演予稿集  2002/11
  • 新規ベンゾ[c]チオフェン誘導体の合成と物性  [Not invited]
    清水祐介, 伊藤智志, 小野昇, 宇野英満
    基礎有機化学連合討論会予稿集  2002/10
  • アセン融合ポルフィリン二量体の合成と物性  [Not invited]
    宇野英満, 桝本茜, 黒木健司, 富永和孝, 小野昇
    基礎有機化学連合討論会予稿集  2002/10
  • 接触皮膚炎 2002 臨床例 (4) 抗菌デスクマットによる接触皮膚炎  [Not invited]
    町野博, 八幡陽子, 宇野英満
    皮膚病診療  2002/10
  • Synthesis of Conjugation-expanded Porphyrins Based on the Retro Diels-Alder Reaction.  [Not invited]
    宇野英満, 小野昇
    有機合成化学協会誌  2002/06 
    Bicyclo-, benzobicyclo-, and naphthobicyclo- [2.2.2] octadiene-fused porphyrins were prepared from ethano-bridged isoindole derivatives via the common methods such as cyclic tetramerization, MacDonald [2+2], and [3+1] porphyrin syntheses. Heating these porphyrins over 200°C caused the retro Diels-Alder reaction leading to quantitative extrusion of ethylene to give the corresponding benzo-, naphtho-, and anthra-fused porphyrins, UV absorption of which showed efficient red-shift compared to those of the starting porphyrins. Upon the thermal treatment, the very bulky bicyclic-ring-fused porphyrins readily soluble in common solvents were converted to the flat, insoluble, conjugation-expanded porphyrins, purification of which often encountered difficulty. This methodology provides not only an easy access to highly conjugated porphyrins and related chromophores in very high quality, but also a significant conversion of soluble dyestuffs to insoluble pigments.
  • Synthesis Study of Pyranoanthraquinone Premithramycinone H.  [Not invited]
    森山佳奈, 宇野英満, 小野昇
    日本化学会講演予稿集  2002/03
  • Synthesis and structural analysis of pyrrole oligomers substituted with bulky electron-withdrawing groups.  [Not invited]
    井上健太郎, 宇野英満, 村嶋貴之, 小野昇
    日本化学会講演予稿集  2002/03
  • Synthesis of hydrophilic porphyrins which can extrude the hydrophilic groups by retro Diels-Alder reaction.  [Not invited]
    宇野英満, 星徹, 小野昇, 石川貴之
    日本化学会講演予稿集  2002/03
  • Synthesis of .pai.-system-expanded compounds using Diels-Alder reactins.  [Not invited]
    秋山泰士, 渡辺光, 小野昇, 宇野英満
    日本化学会講演予稿集  2002/03
  • Synthesis and structure of porphyrins with deep concaves.  [Not invited]
    渡辺光, 小野昇, 宇野英満
    日本化学会講演予稿集  2002/03
  • Synthesis of expanded porphyrin analogues.  [Not invited]
    黒木健司, 村嶋貴之, 宇野英満, 小野昇
    日本化学会講演予稿集  2002/03
  • Synthesis Study of Pyranoanthraquinone AH-1763IIa.  [Not invited]
    井門弓子, 宇野英満, 小野昇
    日本化学会講演予稿集  2002/03
  • Synthesis of porphyrins with sulfur substituents.  [Not invited]
    村嶋貴之, 岡野仁美, 宇野英満, 小野昇
    日本化学会講演予稿集  2002/03
  • Synthesis of 5-membered heterocyclic compounds fused with a bicyclo[2.2.2]octadiene system.  [Not invited]
    宇野英満, 勝山由来子, 星徹, 小野昇
    日本化学会講演予稿集  2002/03
  • Synthesis of bisporphyrins linked with bicyclo[2.2.2]octadiene skeleton.  [Not invited]
    宇野英満, 桝本茜, 中元健一, 小野昇
    日本化学会講演予稿集  2002/03
  • Synthesis and liquid crystalline properties of chiral alkoxy porphyrin.  [Not invited]
    村嶋貴之, 太田光宣, 大島紗智子, 宇野英満, 小野昇
    日本化学会講演予稿集  2002/03
  • Synthesis of thiophene derivatives fused with bicyclo[2.2.2]octadiene.  [Not invited]
    清水祐介, 伊藤智志, 勝山由来子, 宇野英満, 小野昇
    日本化学会講演予稿集  2002/03
  • A Convenient Synthesis of Isothianaphthene Oligomers and their Electrochemical Studies,  [Not invited]
    SHIMIZU Y, SHEN Z, ITO S, UNO H, DAUB J, ONO N
    Tetrahedron Lett.  2002
  • Preparation of Novel Heteroisoindoles from Nitropyridines and Nitropyridones, "Jointly authored"  [Not invited]
    Heterocycles  2002
  • Novel Preparation of beta,beta'-Connected Porphyrin Dimers  [Not invited]
    UNO H, KITAWAKI Y, ONO N
    Chem. Commun.  2002
  • 抗菌デスクマットによる接触皮膚炎、(共著)  [Not invited]
    皮膚病診療  2002
  • Synthesis and Reactivity of Thiophenes Fused with Rigid Bicyclic Ring.  [Not invited]
    宇野英満, 星徹, 勝山由来子, 小野昇
    ヘテロ原子化学討論会講演要旨集  2001/12
  • Synthesis and structure of porphyrins fused with rigid bicyclic ring.  [Not invited]
    渡辺光, 宇野英満, 小野昇
    構造有機化学討論会講演予稿集  2001/10
  • Synthesis of porphyrin containing fused heterocyclic moieties.  [Not invited]
    中元健一, 村嶋貴之, 小野昇, 宇野英満
    構造有機化学討論会講演予稿集  2001/10
  • Synthesis and property of pyrrole oligomers substituted with bulky electron-withdrawing groups at .BETA. position.  [Not invited]
    井上健太郎, 小野昇, 宇野英満
    構造有機化学討論会講演予稿集  2001/10
  • クルクミン類の抗酸化反応のメカニズム  [Not invited]
    水上渉, 徳永愛子, 小原敬士, 長岡伸一, 向井和男, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  2001/10
  • Synthesis and properties of thiophene derivatives fused with bicyclo[2.2.2]octadiene.  [Not invited]
    清水祐介, 伊藤智志, 小川琢治, 村嶋貴之, 小野昇, 宇野英満
    構造有機化学討論会講演予稿集  2001/10
  • Synthesis, structure and function of metalloporphyrins fused with bicyclo[2.2.2]octene frameworks.  [Not invited]
    小野昇, 宇野英満, 伊藤智志, 渡辺光
    錯体化学討論会講演要旨集  2001/09
  • Synthesis and properties of new conjugated systems from π-extended pyrroles  [Not invited]
    Ono Noboru, Ito Satoshi, Uno Hidemitsu
    Technical report of IEICE. OME  2001/05 
    Organic materials containing pyrrole rings such as porphyrins, phtalocynines and poly/oligopyrroles are the most attractive among numerous organic materials. They possess a number of futures that are attractive to material science such as environmental stability, good redox properties, and good electrical conductivity. In this paper we present a brief review of our recent progress of the preparation of pyrrole derivatives, which have potential utility in the field of organic electronics.
  • Synthesis of bispyrroles and bisporphyrins fixed by bicyclic skeleton.  [Not invited]
    中元健一, 伊藤智志, 村嶋貴之, 宇野英満, 小野昇
    日本化学会講演予稿集  2001/03
  • Synthesis of Pyrrole Macrocycles and Their Structures and Properties.  [Not invited]
    麓由美子, 小野昇, 宇野英満
    日本化学会講演予稿集  2001/03
  • Synthesis of compounds having an anthraquinone skeleton fused with a .GAMMA.-pyron ring.  [Not invited]
    井門弓子, 宇野英満, 本田絵里奈, 福原香里, 小野昇
    日本化学会講演予稿集  2001/03
  • Synthesis and reactions of .BETA.,.BETA.'-bis(pentafluorophenyl)pyrroles.  [Not invited]
    井上健太郎, 麓由美子, 小野昇, 宇野英満
    日本化学会講演予稿集  2001/03
  • Synthesis of beta.-beta. linked bis-porphyrin and their properties.  [Not invited]
    北脇有希子, 麓由美子, 小野昇, 宇野英満
    日本化学会講演予稿集  2001/03
  • Synthesis of pyrroles and their oligomers fused with rigid bicyclic rings.  [Not invited]
    渡辺光, 伊藤智志, 小野昇, 宇野英満
    日本化学会講演予稿集  2001/03
  • Synthesis of 1,6- and 1,8-dihydroxyanthraquinones via biomimetic routes.  [Not invited]
    桝本茜, 宇野英満, 長町裕美, 本田絵里奈, 小野昇
    日本化学会講演予稿集  2001/03
  • Synthesis of a Gable Bis-pophyrin Linked with a Bicyclo[2.2.2]octadiene Ring and Its Conversion into a Conjugated Planar Bis-porphyrin,"Jointly authored"  [Not invited]
    ITO S, NAKAMOTO K, UNO H, MURASHIMA T, ONO N
    Chem. Commun.  2001
  • Intramolecular Aldol-type Condensation between Side Chains of Naphthoquinones: Biomimetic Synthesis of 1,6- and 1,8-Dihydroxyanthraquinones, "jointly authored"  [Not invited]
    UNO H, MASUMOTO A, HONDA E, NAGAMACHI Y, YAMAOKA Y, ONO N
    J. Chem. Soc., Perkin Trans. 1  2001
  • Preparation of alpha-Free Pyrroles with Perfluorinated Groups at beta-Positions, "Jointly authored"  [Not invited]
    UNO H, INOUE K, INOUE T, FUMOTO Y, ONO N
    Synthesis  2001
  • Synthesis and Optical Properties of a New Class of Pyrromethene-BF3 Complexes Fused with Rigid Bicyclo Rings and Benzo Derivatives, "Jointly authored"  [Not invited]
    WADA M, ITO S, UNO H, MURASHIMA T, ONO N, URANO T, URANO Y
    Tetrahedron Lett.  2001
  • Electroreduction of β-Hydroxy Phenyl Sulfones in Acetonitrile"Jointly Authored"  [Not invited]
    KUNUGI A, KUDO Y, UNO H
    J. Electroanal. Chem.  2001
  • Cathodic Elimination of β-Acetoxy Phenyl Sulfones in Acetonitrile"Jointly Authored"  [Not invited]
    UNO H, SANO Y, KUNUGI A
    Electrochim. Acta  2001
  • Synthesis of β, β'-(Phenylene)diporphyrins"Jointly Authored"  [Not invited]
    FUMOTO Y, UNO H, TANAKA K, TANAKA M, MURASHIMA T, ONO N
    Synthesis  2001
  • Preparation of (meso)■.-.-Unsubstituted Porphyrins Substituted with Mono- and Tetraformyl and Other Electron-withdrawing Groups"Jointly Authored"  [Not invited]
    Heterocyeles  2001
  • Synthesis and Properties of Polypyrrole Annelated with Bicyclo[2.2.2]octene Units"Jointly Authored"  [Not invited]
    ITO S, WATANABE H, UNO H, MURASHIMA T, ONO N, TSAI Y C, COMPTON R G
    Tetrahedron Lett.  2001
  • Synthesis of Benzoporphyrins Functionalized with Octaester Groups"Jointly Authored"  [Not invited]
    ITO S, UNO H, MURASHIMA T, ONO N
    Tetrahedron Lett.  2001
  • Synthesis of Espicufolin Based on (6-Endo)■.-. Ring Closure of (o)■.-.-Alkynoylnaphthols"Jointly Authored"  [Not invited]
    UNO H, SAKAMOTO K, HONDA E, FUKUHARA K, ONO N, TANAKA J, SAKANAKA M
    J. Chem. Soc., Perkin Trans. 1  2001
  • Synthesis of photo-responsive molecular wire bearing ruthenium complex chromophore.  [Not invited]
    小川琢治, 清水祐介, 増田豪, 前田誠亮, 宇野英満, 小野昇
    ヘテロ原子化学討論会講演要旨集  2000/11
  • Synthesis and discotic liquid crystalline property of Porphyrins with Long Alkoxy and Polyether Chains.  [Not invited]
    伊藤あづさ, 村嶋貴之, 宇野英満, 小川琢治, 小野昇
    ヘテロ原子化学討論会講演要旨集  2000/11
  • Synthesis and Structures of Porphyrinogens and Hexaphyrinogens.  [Not invited]
    宇野英満, 麓由美子, 井上卓思, 井上健太郎, 小野昇
    基礎有機化学連合討論会予稿集  2000/09
  • Synthesis of structure-controlled polypyrroles and the application to modified electrode.  [Not invited]
    小野昇, 伊藤智志, 渡辺光, 落直之, 宇野英満
    エレクトロオーガニックケミストリー討論会講演要旨集  2000/06
  • Cathodic Elimination of .BETA.-Hydroxy and .BETA.-Acetoxy Phenyl Sulfones in Acetonitrile.  [Not invited]
    くぬぎ章, 工藤康洋, 宇野英満
    エレクトロオーガニックケミストリー討論会講演要旨集  2000/06
  • 活性硫黄によるクムレン誘導体への硫黄原子の導入  [Not invited]
    樋口明房, くぬぎ章, 宇野英満
    電気化学会大会講演要旨集  2000/03
  • Synthesis of thiophene .PI.-electronic compounds bearing phenanthroline moiety.  [Not invited]
    小川琢治, 清水祐介, 増田豪, 宇野英満, 小野昇
    日本化学会講演予稿集  2000/03
  • Synthetic Study of Abnormal Amino Acids Based on the Mukaiyama-type Aldol Reaction of the Chiral Siloxypyrroles with Chiral Aldehydes.  [Not invited]
    若狭邦彦, 西原康昭, 宇野英満, 小野昇
    日本化学会講演予稿集  2000/03
  • Synthesis of .BETA.-.BETA. Linked Porphyrin Dimer.  [Not invited]
    北脇有希子, 麓由美子, 小野昇, 宇野英満
    日本化学会講演予稿集  2000/03
  • Synthesis of benzo[h]chromones based on intramolecular alkynoyl transfer followed by ring closure.  [Not invited]
    本田絵里奈, 坂本克治, 宇野英満, 小野昇
    日本化学会講演予稿集  2000/03
  • New Synthesis of Various Benzoporphyrins.  [Not invited]
    落直之, 伊藤智志, 宇野英満, 村嶋貴之, 小野昇
    日本化学会講演予稿集  2000/03
  • Synthesis of Pyrroles and Porphyrins with Long Alkoxy, Crown Ether and Binaphthyl Groups.  [Not invited]
    村嶋貴之, 伊藤あづさ, 小野昇, 宇野英満
    日本化学会講演予稿集  2000/03
  • Synthesis and Physical Properties of Organic Molecules having Photo-Switching Function.  [Not invited]
    小川琢治, 増田豪, 宇野英満, 小野昇
    日本化学会講演予稿集  2000/03
  • A new synthesis of pyrroles fused with rigid bicyclic rings.  [Not invited]
    渡辺光, 伊藤智志, 小野昇, 宇野英満
    日本化学会講演予稿集  2000/03
  • Synthesis of Porphyrin Dimer Linked With p- or m-Benzene Ring.  [Not invited]
    麓由美子, 小野昇, 宇野英満
    日本化学会講演予稿集  2000/03
  • Synthesis and Properties of Tetra-2,3-naphthoporphyrins.  [Not invited]
    伊藤智志, 村嶋貴之, 小野昇, 宇野英満
    日本化学会講演予稿集  2000/03
  • Electrosynthesis of Sulfur-containing Organic Fluorine Compounds from Trifluoromethylated Alkenyl Sulfones and Chlorides Using a Reactive Sulfur-Graphite Electrode"Jointly Authored"  [Not invited]
    Electrochemistry  2000
  • Synthesis and Structures of Pyrroles Fused with Rigid Bicy clic Ring Systems at β-Positions"Jointly Authored"  [Not invited]
    UNO H, ITO S, WADA M, WATANABE H, NAGAI M, HAYASHI A, MURASHIMA T, ONO N
    J. Chem. Soc., Perkin Trans. 1  2000
  • Synthesis and Characterization of N-Confused Porphyrinatoantimony((]G0005[)) : toward a Low Energy Gap Molecular Wire"Jointly Authored"  [Not invited]
    OGAWA T, FURUTA H, TAKAHASHI M, MORINO A, UNO H
    J. Organomet Chem.  2000
  • On the Antioxidant Mechanism of Curcumin : Classical Methods Are Needed to Determine Antioxidant Mechanism and Activity"Jointly Authored"  [Not invited]
    BARCLAY L R C, VINQVIST M R, MUKAI K, GOTO H, HASHIMOTO Y, TOKUNAGA A, UNO H
    Org. Lett.  2000
  • Regioselective Preparation of 1, 6-and 1, 8-Dihydroxy-9, 10-anthraquinones from the Common Intermediates : Synthesis of Aloesaponarin and K1115A"Jointly Authored"  [Not invited]
    Chem. Lett.  2000
  • Preparation of 5-Unsubstituted 4-Formylpyrrole-2-carboxylates and Conversion to Cycloalkano-oligopyrroles"Jointly Authored"  [Not invited]
    FUMOTO Y, UNO H, ITO S, TSUGUMI Y, SASAKI M, KITAWAKI Y, ONO N
    J. Chem. Soc., Perkin Trans. 1  2000
  • Synthesis and Coplanarity-dependent HOMO-LUMO Separation of π-Conjugated Dimers, "Jointly Authored"  [Not invited]
    MURASHIMA T, SHIGA D, NISHI K, UNO H, ONO N
    J. Chem. Soc., Perkin Trans. 1  2000
  • Meso-Unsubstituted Porphyrinogens and Hexaphyrinogens : The First X-Ray Characterization  [Not invited]
    UNO H, INOUE T, FUMOTO Y, SHIRO M, ONO N
    J. Am. Chem. Soc  2000
  • A New Synthesis of [2,3]naphthoporphyrins  [Not invited]
    ITO S, OCHI N, UNO H, MURASHIMA T, ONO N
    Chem Commun  2000
  • A New Approach for Construction of Quarternary Chiral Centers : Preparation of α-Branched Serine Derivatives  [Not invited]
    Heterocycles  2000
  • A Novel Synthetic Approach to Benzo[h]chromones via Sequential Intramolecular Alkynoyl Transfer Followed by 6-endo Ring Closure  [Not invited]
    SAKAMOTO K, HONDA E, ONO N, UNO H
    Tetrahedron Lett  2000
  • Synthesis and X-ray Structure of Stable 2H-Isoindoles  [Not invited]
    MURASHIMA T, TAMAI R, NISHI K, NOMURA K, FUJITA K, UNO H, ONO N
    J. Chem. Soc., Perkin Trans.1  2000
  • Thermal and Photochemical Isomerization of Tetraaryl Tetrakistrifluoromethyl [4]Radialenes  [Not invited]
    UNO H, KASAHARA K, NIBU N, NAGAOKA S, ONO N
    J. Org. Chem  2000
  • A New Synthesis of Benzoporphyrins Using 4,7-Dihydro-4,7-ethano-2H-isoindole as an Isoindole Equivalent  [Not invited]
    Heterocycles  2000
  • Synthesis of Pyrroles Based on the Barton-Zard Reaction Using Vinyl Sulfones.  [Not invited]
    宇野英満, 伊藤智志, 麓由美子, 井上卓思, 小野昇
    ヘテロ原子化学討論会講演要旨集  1999/11
  • Study on photo- and electric properties of functional thiol molecules by using nano-gap gold electrodes.  [Not invited]
    小川琢治, 増田豪, 宇野英満, 小野昇
    ヘテロ原子化学討論会講演要旨集  1999/11
  • Synthetic Study of Abnormal Amino Acids Based on Michael Addition of the Siloxypyrrole with Nitro Olefins.  [Not invited]
    笠原健一, 宇野英満, 小野昇
    複素環化学討論会講演要旨集  1999/11
  • Synthesis of pyrrole oligomers and porphyrins fused with bicyclo[2.2.2]octane units and a new synthesis of benzoporphyrins using pyrrole fused with bicyclo[2.2.2]octadiene ring.  [Not invited]
    伊藤智志, 落直之, 村嶋貴之, 小野昇, 宇野英満
    複素環化学討論会講演要旨集  1999/11
  • Rearrangement of [4]Radialenes.  [Not invited]
    宇野英満, 笠原健一, 小野昇
    日本化学会講演予稿集  1999/09
  • ジヒドロキシアントラキノン類の合成研究  [Not invited]
    宇野英満, 長町裕美, 本田絵里奈, 小野昇
    日本化学会中国四国・同九州支部合同大会講演要旨集  1999/09
  • 反応性硫黄電極を用いてのCF3基を有するエチレン誘導体からの含硫黄有機化合物の電解合成  [Not invited]
    内藤修一, JABBAR M A, くぬぎ章, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  1999/09
  • Electrosynthesis of sulfur-containing organic compounds from sulfonyl-substituted 2-alkenenitriles using a reactive sulfur electrode.  [Not invited]
    くぬぎ章, 井辻一成, 森和代, 宇野英満
    エレクトロオーガニックケミストリー討論会講演要旨集  1999/07
  • β‐ヒドロキシおよびβ‐アセトキシスルホンの電解還元脱硫反応  [Not invited]
    くぬぎ章, 工藤康洋, 佐野祥嗣, 宇野英満
    電気化学会大会講演要旨集  1999/03
  • Synthesis of a Novel Meso-Unsubstituted Calix[4]Pyrrole and Its Property.  [Not invited]
    麓由美子, 村嶋貴之, 小野昇, 宇野英満
    日本化学会講演予稿集  1999/03
  • Synthetic Study of Abnormal Amino Acids by Michael Addition of the Siloxypyrrole with Nitro Olefins.  [Not invited]
    笠原健一, 宇野英満, 小野昇
    日本化学会講演予稿集  1999/03
  • Synthesis of Novel Porphyrins and Porphyrinogens Substituted with Trifluoromethyl Group.  [Not invited]
    井上卓思, 村嶋貴之, 小野昇, 宇野英満
    日本化学会講演予稿集  1999/03
  • Preparation of Long-Chain Porphyrin Arrays by Step-Wise Oxidative Couplings.  [Not invited]
    小川琢治, 高上拓也, 宇野英満, 小野昇, 大須賀篤弘
    日本化学会講演予稿集  1999/03
  • Synthetic Study of Espicufolin. (4).  [Not invited]
    本田絵里奈, 坂本克治, 宇野英満, 小野昇
    日本化学会講演予稿集  1999/03
  • Construction of Highly Functional Photo-Switching Molecular Electronics Devices Using Gold Nano Particles and Ruthenium Complexes.  [Not invited]
    小川琢治, 増田豪, 宇野英満, 小野昇
    日本化学会講演予稿集  1999/03
  • Synthesis of porphyrin Mn complex with Bitetralin Substituent as Chiral Auxiliary.  [Not invited]
    村嶋貴之, 伊藤あづさ, 小野昇, 宇野英満
    日本化学会講演予稿集  1999/03
  • Synthesis of .ALPHA.,.BETA.-linked Calix[3]Pyrroles from .BETA.-Formyl Pyrrol and their Structures.  [Not invited]
    佐々木真紀, 麓由美子, 小野昇, 伊藤智志, 村嶋貴之, 宇野英満
    日本化学会講演予稿集  1999/03
  • Synthesis of bismuth porphyrin derivatives and their electrochemical oxidation.  [Not invited]
    小川琢治, 平田慈, 宇野英満, 小野昇
    日本化学会講演予稿集  1999/03
  • Synthesis and Properties of Rigid Porphyrins fused with Bicyclo[2.2.2]octene Units  [Not invited]
    ITO S, UNO H, MURASHIMA T, ONO N
    J. Chem. Soc., Chem. Commun  1999
  • Electrosynthesis of Isothiazoles from Sulfonyl-substituted 2-Alkenenirile Using a Reactive Sulfur-Graphite Electrode  [Not invited]
    KUNUGI A, JABBAR M A, MORI K, UNO H
    Electrochim. Acta  1999
  • Synthesis of Pyrrolostatin and its Analogues"Jointly Authored"  [Not invited]
    FUMOTO Y, EGUCHI T, UNO H, ONO N
    J. Org. Chem.  1999
  • Total Synthesis of (S)-Espicufolin and Absolute Structure Retermination of Espicufolin. "Jointly Authored"  [Not invited]
    J. Chem. Soc. , Chem. Commun.  1999
  • Stereochemical Study of a Lewis Acid-promoted Reaction of Silyloxypyrrole with Aliphatic and Aromatic Aldehyokes "Jointly Authored"  [Not invited]
    Bull. Chem. Soc. Jpn  1999
  • Reinrestigation of the Coupling Reaction of 2-Aryl-1,1-dibromo-3,3,3-trifluoropropenes. Preparation of Perfluoroalkylated [3]Cunulenes. "Jointly Authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1999
  • Electrosynthesis of Sulfur-containing Organic Fluorine compounds from Trifluoromethyl-substituted Cumulene Derivatives using a sacrificial sultur-Graphite Electrode"Jointly Authored"  [Not invited]
    KUNUGI A, HAYASHI K, YUMOTO H, UNO H
    Electrochim. Acta  1999
  • Preparation of Pyrrole-2-carboxylates with Electron-withdrawing Groups at the 4-Position"Jointly authored"  [Not invited]
    UNO H, TANAKA M, INOUE T, ONO N
    Synthesis  1999
  • 消耗性電極を用いた含フッ素オレフィンの変換反応の開発 (文部省S)  [Not invited]
    宇野英満
    有機化学新現象-多元素協同作用に基づく炭素共有結合形成の新機軸 平成10年度成果報告書  1999
  • Synthesis of New Bismuth Porphyrins and their Electrochemistry.  [Not invited]
    小川琢治, 平田慈, 小野昇, 宇野英満
    ヘテロ原子化学討論会講演要旨集  1998/12
  • メソ‐無置換‐β‐アリールポルフィリンの合成とその機能  [Not invited]
    麓由美子, 村嶋貴之, 小野昇, 宇野英満
    複素環化学討論会講演要旨集  1998/11
  • Electrosynthesis of Sulfur-Containing Organic Compounds from Vinyl Sulfones having a CN group using a S-C Electrode.  [Not invited]
    くぬぎ章, 森和代, JABBAR A, 本田絵理奈, 宇野英満
    電気化学秋季大会講演要旨集  1998/10
  • Isomerization of Radialenes Bearing Trifluoromethyl Groups.  [Not invited]
    宇野英満, 笠原健一
    日本化学会講演予稿集  1998/09
  • Preparation of Bismuth(V) Porphyrin Derivatives by Electrochemical Oxidation.  [Not invited]
    小川琢治, 平田慈, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/09
  • Synthetic Study of 4H-Naphtho[2,3-h]chromen-4-one.  [Not invited]
    本田絵里奈, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/09
  • Synthetic study of Espicufolin. (3).  [Not invited]
    坂本克治, 本田絵里奈, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/09
  • Synthesis of the 15th Group Element N-Confused Porphyrins.  [Not invited]
    小川琢治, 森野綾子, 宇野英満, 小野昇, 古田弘幸
    日本化学会講演予稿集  1998/09
  • Construction of Photo-Switching Molecular Devices Using Gold Nano Particles and Ruthenium Complexes.  [Not invited]
    小川琢治, 増田豪, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/09
  • A New Symthesis of Beta-Trifluoromethylpyrroles.  [Not invited]
    井上卓思, 村嶋貴之, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/09
  • Michael Addition of Optically Active Siloxypyrrole with Nitro Olefins.  [Not invited]
    笠原健一, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/09
  • Double Stereoselection in the Reaction of Optically Active Siloxypyrrole with Chiral Aldehydes.  [Not invited]
    西原康昭, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/09
  • Synthetic Study of Espicufolin. (2) Synthesis of Anthraquinone Moiety.  [Not invited]
    山岡陽太郎, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • Stereoselectivity in the Alkylation of Optically Active Bicyclic Siloxypyrroles.  [Not invited]
    笠原健一, 西原康昭, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • Construction of Photo-switching Molecular Devices Using Gold Nano Particles and Ruthenium Complexes.  [Not invited]
    小川琢治, 増田豪, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • Synthesis and Properties of 5,6-Disubstituted Acenaphtho 1,2c pyrrole Monomers and Their Polymers.  [Not invited]
    白石篤志, 村嶋貴之, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • A New Synthesis of .BETA.-Trifluoromethylpyrroles.  [Not invited]
    井上卓思, 村嶋貴之, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • Structure of Neoilludin from Lampteromyces japonicus.  [Not invited]
    月原拓也, 倉本誠, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • Synthesis of D4 Symmetrical Porphyrin with Binaphthyl Substituent as Chiral Auxiliary.  [Not invited]
    村嶋貴之, 内原有紀, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • Electrochemistry of Bismuth Porphyrin Derivatives.  [Not invited]
    小川琢治, 平田慈, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • Synthesis of .BETA.-Formylpyrroles and Application to Synthesis of Novel Pyrroles.  [Not invited]
    麓由美子, 伊藤智志, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • Stereospecific Isomerization of Cumulenes and Radialenes Bearing Trifluoromethyl Groups.  [Not invited]
    宇野英満, 山岡陽太郎, 笠原健一
    日本化学会講演予稿集  1998/03
  • Stereochemical Selectivity in the Lewis Acid-Promoted Reaction of 2-Siloxy-pyrrole and -Furan with Various Adehydes. (2).  [Not invited]
    西原康昭, 溝部昇, 宇野英満, 小野昇
    日本化学会講演予稿集  1998/03
  • A New Synthesis of Benzoporphyrins Using 4,7-Dihydro-4,7-ethano-2H-isoindole as a Synthon of Isoindole "jointly authored"  [Not invited]
    ITO S, MURASHIMA T, UNO H, ONO N
    J. Chem. Soc. , Chem. commun.  1998
  • Highly Soluble Poly(1,3,4-trisubstituted-2,5-pyrrolenevinylenes) "jointly authored"  [Not invited]
    MURASHIMA T, HIRAI K, UNE Y, UCHIHARA Y, UNO H, ONO N
    Tetrahedron Lett.  1998
  • Cathodic Cleavage of 1-Trifluoromethyl Alkenyl Sulfone and Sulfoxide "jointly authored"  [Not invited]
    JABBAR M A, BITO S, KUNUGI A, UNO H
    Electrochim. Acta  1998
  • Stereochemical Change in the Lewis Acid-promoted Reaction of 2-Siloxypyrrole Derived from (L)-Glutamic Acid. Synthesis of a Lactacyptin Analogue "Jointly authored"  [Not invited]
    Heterocycles  1998
  • Stereoselective Isomerization of Tetrakistrifluoromethyl Tetraaryl [4] Radialenes to the Type II (All-Z) Isomers "jointly authored"  [Not invited]
    UNO H, NIBU N, YAMAOKA Y, MIZOBE N
    Chem. Lett.  1998
  • Synthetic Study on the Compounds with Neurotrophic Activity.  [Not invited]
    宇野英満
    旭硝子財団助成研究成果報告(Web)  1997/12
  • 硫黄‐炭素電極を用いてのシアノ基を有するビニルスルホン類からの含硫黄有機化合物の合成  [Not invited]
    くぬぎ章, 森和代, 山岡陽太郎, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  1997/11
  • Vilsmeier reaction.  [Not invited]
    宇野英満
    化学  1997/09
  • Electrosynthesis of Sulfur-Containing Organic Compounds from Cumulenes having CF3 Using a Sacrificial Sulfur-Graphite Electrode.  [Not invited]
    くぬぎ章, 林圭一, 溝淵昇, 宇野英満
    電気化学秋季大会講演要旨集  1997/08
  • Synthetic Study of Broussonetines, a Pyrrolidine Alkaloid Family with Glycosidase Inhibitory Activities. (2).  [Not invited]
    湯本裕之, 宇野英満
    日本化学会講演予稿集  1997/03
  • Electroreductive Elimination of .BETA.-Acetoxy Sulfones.  [Not invited]
    くぬぎ章, 佐野祥嗣, 宇野英満
    電気化学会大会講演要旨集  1997/03
  • Study on Stereoselective Synthesis of Trifluoromethylated Cumulenes and Their Thermal Dimerization to 4 Radialenes.  [Not invited]
    二歩伸匡, 宇野英満, 溝部昇
    日本化学会講演予稿集  1997/03
  • Electrochemical Desulfurization of .ALPHA.-Trifluoromethyl Vinyl Sulfone and Sulfoxide.  [Not invited]
    くぬぎ章, 尾藤誠二, JABBAR M A, 宇野英満
    電気化学会大会講演要旨集  1997/03
  • Synthesis and Evaluation of Antioxidant Activity of Pyrrolostatin and its Derivatives.  [Not invited]
    麓由美子, 江口智美, 小野昇, 宇野英満
    日本化学会講演予稿集  1997/03
  • Stereoselectivity in the Reaction of Siloxy-pyrrole and-furan with Various Aldehydes.  [Not invited]
    溝部昇, 宇野英満
    日本化学会講演予稿集  1997/03
  • Synthetic Study of BU-4514N.  [Not invited]
    山岡陽太郎, 宇野英満
    日本化学会講演予稿集  1997/03
  • Synthesis of Crowned Porphyrins with Chiral Cavity.  [Not invited]
    村嶋貴之, 内原有紀, 宇野英満, 小野昇
    日本化学会講演予稿集  1997/03
  • Electrosynthesis of Sulfur-containing Organic Fluorine Compounds from Trifluoromethyl-substituted 1,1-Dibromoalkenes Using a Sacrificial Sulfur-Graphite Electrode "jointly authored"  [Not invited]
    "Electrochemistry in the Preparation of Fluorine and its compounds" The Electrochenical Society, Inc.  1997
  • Electrosynthesis of Sulfur-containing Organic Compounds from Cumulene Derivatives Using a Sacrificial Sulfur-graphite Electrode "Jointly authored"  [Not invited]
    KUNUGI A, KUWAMURA K, UNO H
    Electrochim. Acta  1997
  • Stereocontrolled Mukaiyama-type Aldol Reaction of Siloxypyrroles Derived from (S)-Glutamic Acid "Jointly authored"  [Not invited]
    Synlett  1997
  • Ambident Reactivity of Nitro Heteroaromatic Anions "Jointly authored"  [Not invited]
    MURASHIMA T, TAMAI R, FUJITA K, UNO H, ONO N
    Tetrahedron Lett.  1997
  • Electrosynthesis of Sulfur-Containing Organic Compounds from Bromoalkenes Using a Sacrificial Sulfur-Graphite Electrode.  [Not invited]
    越智誠, くぬぎ章, 宇野英満
    エレクトロオーガニックケミストリー討論会講演要旨集  1997
  • Synthesis of Pyrroles Having Oxygen Substituents at 3,4-Position.  [Not invited]
    村嶋貴之, 内原有紀, 宇野英満, 小野昇
    日本化学会講演予稿集  1996/09
  • Electrochemical Reduction of 1,1-Dibromoalkenes Using a Sacrificial Mixed Sulfur/Graphite Electrode.  [Not invited]
    くぬぎ章, 越智誠, 宇野英満
    電気化学秋季大会講演要旨集  1996/09
  • Synthesis of Porphyrins and pyrroles with Electron withdrawing groups at .BETA.-position.  [Not invited]
    小野昇, 田中正則, 村嶋貴之, 宇野英満
    日本化学会講演予稿集  1996/09
  • Crown Ether-Annulated Porphyrins Designed as the Multi Ion Receptors.  [Not invited]
    村嶋貴之, 内原有紀, 宇野英満, 小川琢治, 小野昇
    日本化学会講演予稿集  1996/09
  • Synthesis of antioxidant active pyrroles substituted with unsaturated long alkyl chains.  [Not invited]
    小野昇, 麓由美子, 村嶋貴之, 小川琢治, 宇野英満
    日本化学会講演予稿集  1996/09
  • Synthetic Study of Broussonetines, a Pyrrolidine Alkaloid Family with Glycosidase Inhibitory Activities.  [Not invited]
    湯本裕之, 宇野英満, 小野昇
    日本化学会講演予稿集  1996/03
  • The Regio- and Stereoselectivities in the Reaction of Optically Active, 3-Substituted 5-Siloxy-1H-pyrrolo 1,2-c oxazoles.  [Not invited]
    山岡陽太郎, 溝部昇, 宇野英満
    日本化学会講演予稿集  1996/03
  • Synthesis of Porphyrins with Electron withdrawing groups at .BETA.-position.  [Not invited]
    田中正則, 村嶋貴之, 宇野英満, 小野昇
    日本化学会講演予稿集  1996/03
  • Synthesis of Pyrroles and Porphyrins with Long Alkoxyl Groups or Crown Ethers.  [Not invited]
    村嶋貴之, 内原有紀, 宇野英満, 小野昇
    日本化学会講演予稿集  1996/03
  • A New Synthesis of 1-Phenylthio-and 1-Alkylamino-4-nitrobuta-1,3-dienes "Jointly authored"  [Not invited]
    J. Chem. Soc. , Perkin Trans. 1  1996
  • A New Facet of the Reaction of Nitro Heteroaromatic Compounds with Ethyl Isocyanoacetate "Jointly authored"  [Not invited]
    J. Chem. Soc. , Perkin Trans. 1  1996
  • A Norel Trimerization of 1-Phenylsulfany 1-2,2,2-trigluoroethyl Isocyanide Giving a Dihydropyrimidine Derivative "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1996
  • The First Preparation of Crown Ether-Annulated Porphyrin "Jointly authored"  [Not invited]
    MURASHIMA T, UCHIHARA Y, WAKAMORI N, UNO H, OGAWA T, ONO N
    Tetrahedron Lett.  1996
  • A New Route to Porphyrins Substituted with Long Alkoxy Groups, Attempts to Prepare the Discotic Liquid Crystals "Jointly authored"  [Not invited]
    Mol. Cryst. Lig. Cryst.  1996
  • Reaction of 2-Nitroenamines and 2-Nitroalkenyl Sulides with Ethyl Isocyanoacetate : Novel Synthesis of 1-Hydroxypyrazoles "Jointly authored"  [Not invited]
    J. Chem. Research  1996
  • A New Route to Porphyins Substituted with Long Alkoxy Groups.  [Not invited]
    村嶋貴之, 若森尚子, 内原有紀, 宇野英満, 小川琢治, 小野昇
    有機反応化学討論会研究発表・講演予稿集  1995/10
  • Synthesis of a porphyrin and zinc complex with a long chain alkoxyl group.  [Not invited]
    村嶋貴之, 内原有紀, 若森尚子, 宇野英満, 小野昇
    日本化学会中国四国・同九州支部合同大会講演要旨集  1995/09
  • Synthetic research of 7-desmethyl lactacysteine.  [Not invited]
    山岡陽太郎, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  1995/09
  • Synthesis of an aromatic condensed ring thiophene with conductivity and optical functions by the control of a bandgap.  [Not invited]
    小野昇, 田中桂, 村嶋貴之, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  1995/09
  • Synthesis of lactacysteine analogue with a different hydrophobic side-chain.  [Not invited]
    溝部昇, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  1995/09
  • Synthesis of 3 - alkyl and 3,4 - dialkyl pyrroles.  [Not invited]
    小野昇, 村嶋貴之, 江口智美, 小川琢治, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  1995/09
  • Synthetic research of 3,4 - dihydroxy - 5 - oxo prolinal.  [Not invited]
    湯本裕之, 宇野英満, 小野昇
    日本化学会中国四国・同九州支部合同大会講演要旨集  1995/09
  • 硫黄‐炭素混合電極を用いたクムレンの電解還元  [Not invited]
    桑村貴実子, 河村保彦, くぬぎ章, 宇野英満
    エレクトロオーガニックケミストリー討論会講演要旨集  1995/06
  • Synthesis of 3,4-Dialkoxypyrroles.  [Not invited]
    小野昇, 若森尚子, 村嶋貴之, 小川琢治, 宇野英満
    日本化学会講演予稿集  1995/03
  • Synthesis of Lactacystin Analogues with Neurotrophic Activity.  [Not invited]
    溝部昇, 宇野英満, 小野昇
    日本化学会講演予稿集  1995/03
  • Trimerization of (1-Phenylthio)-2,2,2-trifluoroethyl Isonitrile.  [Not invited]
    宇野英満, 岡健嗣, 小野昇
    日本化学会講演予稿集  1995/03
  • Stereocontrol on Introduction of Methyl and Hydroxyl Groups in .GAMMA.-Lactam Ring.  [Not invited]
    宇野英満, 津崎誠
    日本化学会講演予稿集  1995/03
  • Synthesis of Pyrazoles from Nitroenamines and Isonitriles.  [Not invited]
    小野昇, 木下智仁, 村嶋貴之, 小川琢治, 宇野英満
    日本化学会講演予稿集  1995/03
  • Electrochemical Method to Vinyl Fluorides (II). Cathodic Cleavage and Carboxylation of 1-Fluoro-2-(4-biphenylyl)vinyl Phenyl Sulphoxide in Nonaqueous Media "Jointly authored"  [Not invited]
    KUNUGI A, MORI S, KOMATSU S, MATSUI H, UNO H, SAKAMOTO K
    Electrochimica Acta  1995
  • Electrochemical Method to Vinyl Fluorides III. Electrochemical Cleavage of 1-Fluoro-2-arylvinyl Phenyl Sulfoxides in Acetonitrile. "Jointly authored"  [Not invited]
    DENKI KAGAKU  1995
  • ニトロエナミンとイソニトリルの反応を利用したピラゾールの合成  [Not invited]
    小野昇, 木下智仁, 村嶋貴之, 小川琢治, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  1994/10
  • トリフルオロメチル基を持つイソニトリル類の合成と反応  [Not invited]
    宇野英満, 岡健嗣, 小野昇
    日本化学会中国四国・同九州支部合同大会講演要旨集  1994/10
  • L‐グルタミン酸を出発原料とする生理活性ピロリジン化合物の合成  [Not invited]
    津崎誠, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  1994/10
  • 3,4‐ジアルコキシピロール及びポリピロールの合成  [Not invited]
    小野昇, 若森尚子, 村嶋貴之, 小川琢治, 宇野英満
    日本化学会中国四国・同九州支部合同大会講演要旨集  1994/10
  • Total Synthesis of Lactacystin.  [Not invited]
    宇野英満, BALDWIN J E
    日本化学会講演予稿集  1994/03
  • Synthesis of Lactacystin Analogues with Neurotrophic Activity.  [Not invited]
    岩井樹, 宇野英満, 小野昇, BALDWIN J E
    日本化学会講演予稿集  1994/03
  • Total Synthesis of (+)-Lactacystin from (R)-Glutamate "Jointly authored"  [Not invited]
    UNO H, BALDWIN J E, RUSSELL A T
    J. Am. Chem. Soc  1994
  • A New Approach to β-Fluoropyrroles Based on the Michael Addition of Isocyanomethylide Anions to α-Fluoroalkenyl Sulfones and Sulfoxides "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn  1994
  • Nucleophilic Perfluoroalkylation Using Perfluoroalkyllithiums. "Jointly authored"  [Not invited]
    Synlett  1993
  • Electrochemical Method to Vinyl Fluorides-1. Cathodic Elimination of 1-Fluoro-2-Arylvinyl Phenyl Sulphones in Acetonitrile. "Jointly authored"  [Not invited]
    KUNUGI A, YAMANE K, YASUZAWA M, MATSUI H, UNO H, SAKAMOTO K
    Electrochimica Acta  1993
  • Reaction of 2-Isoxazolines with Organolithiums in the Presence of Boron Trifluoride. "Jointly authored"  [Not invited]
    UNO H, TERAKAWA T, SUZUKI H
    Bull. Chem. Soc. Jpn.  1993
  • Behaviors of α-Fluorocarbenoids Derived from the Nucleophilic Desulfinylation of α-Chloro-α-fluoroalkyl Sulfoxides. "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1992
  • Nucleophilic Desulfinylation of α-Fluoro-β-(alkoxy and siloxy) Sulfoxides. Effects of the β-Oxy Substituents on Protonation, 1,2-Hydrogen Migration, and Nucleophile Addition to the Fluorocarbenoid Centers. "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1992
  • Boron Trifluoride-assisted Perfluoroalkylation of Carbon-Nitrogen Double Bonds.  [Not invited]
    UNO H, OKADA S, ONO T, SHIRAISHI Y, SUZUKI H
    J. Org. Chem.  1992
  • Perfluoroalkyl Migration in the Rearrangement of 4-Perfluoroalkyl-4-quinols."Jointly authored"  [Not invited]
    UNO H, YAYAMA A, SUZUKI H
    Tetrahedron  1992
  • α‐フルオロアルケニルスルホン及びスルホキシドのMichael付加反応による含フッ素化合物の合成  [Not invited]
    富永貴司, 坂本克治, 宇野英満, 小野昇
    日本化学会中国四国・同九州支部合同大会講演要旨集  1991/10
  • 4‐ペルフルオロアルキルキノールの塩基触媒転位反応  [Not invited]
    宇野英満, 矢山亜由美, 鈴木仁美
    日本化学会講演予稿集  1991/03
  • オキシムエーテルと有機リチウムの反応を利用したヒドロキシルアミン類の合成  [Not invited]
    寺川哲也, 宇野英満, 鈴木仁美
    日本化学会講演予稿集  1991/03
  • α‐フルオロアルケニルスルホンを用いた4‐フルオロピロールの合成  [Not invited]
    坂本克治, 宇野英満, 小野昇
    日本化学会講演予稿集  1991/03
  • 1,2-Migration of Perfluoroalkyl Groups in Anionotropic Rearrangement. The Acyloin Rearrangement of 4-Perfluoroalkyl-4-quinols. "Jointly authored"  [Not invited]
    Chem. Lett.  1991
  • Rearrangement of 4-Perfluoroalkyl Quinols "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1991
  • A Novel Method for the Synthesis of 4-Isoquirolinols "Jointly authored"  [Not invited]
    UNO H, OKADA S, SUZUKI H
    J. Heterocycl. Chem.  1991
  • Boron Trifluoride-promoted Addition of Organolithiums to Oxime Ethers. A Facile Synthesis of Substituted Hydroxylamines. "Jointly authored"  [Not invited]
    UNO H, TERAKAWA T, SUZUKI H
    Synlett  1991
  • Preparation of Perfluoroalkyl Azaarenes with a Perfluoroalkyllithium-Boron Trifluoride System. "Jointly authored"  [Not invited]
    UNO H, OKADA S, SUZUKI H
    Tetrahedron  1991
  • ペルフルオロアルキルキノールの転位反応における位置選択性  [Not invited]
    矢山亜由美, 宇野英満, 鈴木仁美
    日本化学会講演予稿集  1990/09
  • Cathodic desulfonylation of 1-fluoro-1-phenylsulfonyl-2-p-tolylethene.  [Not invited]
    わぬぎ章, 山根賢治, 安沢幹人, 坂本克治, 宇野英満
    電気化学協会大会講演要旨集  1990/03
  • A Conbenient Synthesis of 4-(Perfluoroalkyl)pyrimidines and 4-(Perfluoroalkyl) tetrahydropyrimidines "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1990
  • Preparation of Perfluoroalkyl Ketones by the Reaction of Perfluoroalkyllithiums with Esters "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1989
  • Boron Trifluoride-Assisted Alkylation of 2-Isoxazolines. A Novel Route to N-Unsubstituted Isoxazolidines "Jointly authored"  [Not invited]
    Chem. Lett.  1989
  • A Novel Route to 6-Perfluoroalkyluracils "Jointly authored"  [Not invited]
    UNO H, TERAKAWA T, SUZUKI H
    Synthesis  1989
  • A Novel Generation and Behavior of Alkylfluorocarbenoids from α,α-Chlorofluoroalkyl Sulfoxides "Jointly authored"  [Not invited]
    UNO H, SEMBA F, TASAKA T, SUZUKI H
    Chem. Lett.  1989
  • Stepwise Intromolecular Cycloaddition of Nitrile Oxide Equivalents Derived from the Lewis Acid-promoted Reaction of 1-Nitroalkadienes and Allylic Stannanes "Jointly authored"  [Not invited]
    UNO H, GOTO K, WATANABE N, SUZUKI H
    J. Chem. Soc. Perkin Trans. 1  1989
  • Boron Trifluoride-Assisted Ziegler-Zeiser Reaction of Perfluoroalkyllithiums. An Efficient Synthesis of Perfluoroalkylated Heterocycles "Jointly authored"  [Not invited]
    Chem. Lett  1988
  • Boron Trifluoride-Assisted Reaction of Perfluoro-alkyllithiums with Imines. A Novel Route to Perfluoroalkylated Amines "Jointly authored"  [Not invited]
    Chem. Lett.  1988
  • Perfluoroalkyl-thwarted Rearrangement of Quinol Esters. Formation of Catechol Derivatives via 1,3-Migration of Acyloxy Group "Jointly authored"  [Not invited]
    Chem. Lett  1988
  • Fluorinated Tertiary Thio and Selenoethers from the Reaction of Sulfenyl or Selenenyl Chloride with Perfluoropropene Dimers in the Presence of Alkali Fluoride "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1987
  • A Novel Synthesis of Bicyclic Isoxazolines via Sequential Michael and Intramolecular 1,3-Dipolar Additions "Jointly authored"  [Not invited]
    UNO H, WATANABE N, FUJIKI S, SUZUKI H
    Synthesis  1987
  • An Efficient Synthesis of Perfluoroalkyl Ketones Using Perfluoroalkyllithiums "Jointly authored"  [Not invited]
    Chem. Lett.  1987
  • Bis[perfluoro(1,1-dimethylbutyl] Trisulfide from the Cesium Fluoride-Assisted Reaction of Hexafluoro-Propene Dimers with Disulfur Dichloride "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1987
  • Regioselective Carboxylation of Silicon-Stabilized Allylic Carbanions and the Synthetic Utility of 2-Silyl-3-butenoates  [Not invited]
    Bull. Chem. Soc. Jpn.  1986
  • A New Synthesis of α-Phenylhomoallylnitriles from β-Nitrostyrene and Allylic Silanes "Jointly authored"  [Not invited]
    Bull. Chem. Soc. Jpn.  1986
  • Allylation of 2-Alkanoyl 1,4-Qninones with Allylsilanes and Allylstannanes. Efficient Synthesis of Pyranonaphtno-quinone Antibiotics  [Not invited]
    J. Org. Chem  1986
  • Synthesis of Aklavinones. Application of the Stereocontrolled "Zipper" Bicyclo-Cyclization Reaction "Jointly authored"  [Not invited]
    Tetrahedron  1984
  • Total Synthesis of (±)-Aklavinone via Biomimetic Route. Application of an Efficient "Zipper" Reaction-Stereocontrolled One-Step Bicyclo-Cyclization "Jointly authored"  [Not invited]
    Chem. Lett.  1983
  • Synthesis of 11-Deoxyanthracyclinone Precursor. A Nes Strategy toward Tetracyclic System via Tandem 1,4/[4+2] Addition "Jointly authored"  [Not invited]
    Chem. Lett.  1983
  • Synthetic Approach toward Mitomycins. Efficient Synthesis of Mitosane Precursors from (2,4-Pentaclienyl)-p-quinones "Jointly authored"  [Not invited]
    Chem. Lett.  1982
  • New Synthesis of Methyl 2-Triorganosilyl-3-butenoates as a New Synthon of 3-Methoxycarbonylallyl Anion "Jointly authored"  [Not invited]
    Chem. Lett.  1982
  • New Synthetic Approach to Pyranonaphthoquinone Antibiotics, (±)-Deoxyfrenolicin "Jointly authored"  [Not invited]
    Chem. Lett.  1982
  • シンナミルトリメチルすずによるキノンの位置選択的アリル化反応 ルイス酸を用いるアリル化位置の制御による(±)‐4‐メトキシダルベルジオンの合成  [Not invited]
    成田吉徳, 宇野英満, 丸山和博
    日本化学会誌  1981/05
  • Regioselective Allylation of Methoxy-p-benzoquinone by trans-Cinnamyltrimethyltin-Control of Regio-Chemistry of Allylation by Use of BF3・OE+2 and Synthesis of (±)-4-Methoxydalbergione "Jointly authored"  [Not invited]
    Journal of the Chemical Society of Japan, Chemistry and Industrial Chemistry  1981
  • Lewis Acid Mediated Allylation of 2-Alkanoyl-1,4-quinones with Allylsilane and Allylstannane "Jointly authored"  [Not invited]
    NARUTA Y, UNO H, MARUYAMA K
    Tetrahedron Lett.  1981
  • Synthesis of (±)-Eleutherin, (±)-Isoeleutherin, and their Demethoxy Analogues. A Novel Synthetic Approach "Jointly authored"  [Not invited]
    NARUTA Y, UNO H, MARUYAMA K
    J. Chem. Soc., Chem Commun.  1981

Works

  • フタロシアニンブランチポリマーの開発
    2010 -2011
  • 超耐熱性可視光吸収色素及び色素増感用赤外吸収色素の開発
    2010 -2011
  • 臭素を含む機能材料の探索研究
    2009 -2010
  • 有機EL発光材料の可溶化と塗布型プロセスへの適用
    2009 -2010
  • 前駆体塗布法有機電界効果型トランジスタ作成用試薬の開発
    2009 -2009
  • キシレン類の選択的ハロゲン化とその誘導体に関する研究
    2007 -2009
  • 前駆体塗布法による有機電界効果型トランジスタの開発
    2008 -2008
  • オルト置換芳香族ハロゲン化合物の高効率アミノ化の研究
    2007 -2008
  • 電極/有機分子完全コンジュゲート系の有機合成的手法による実現
    2007 -2007
  • オルト置換芳香族ハロゲン化合物の高効率アミノ化の研究
    2006 -2007
  • 含フッ素芳香族ニトリル化合物誘導体合成に関する研究
    2006 -2006
  • 電極/有機分子完全コンジュゲート系の有機合成的手法による実現
    2006 -2006
  • 共役拡張分子の新合成とエレクトロニクスへの応用
    2005 -2006
  • 含フッ素芳香族ニトリル化合物誘導体合成に関する研究
    2005 -2005
  • 電極/有機分子完全コンジュゲート系の有機合成的手法による実現
    2005 -2005
  • Study on synthesis of fluorine-containing aromatic derivatives
    2005 -2005
  • 共役拡張分子の新合成とエレクトロニクスへの応用
    2004 -2005
  • 電極/有機分子完全コンジュゲート系の有機合成的手法による実現
    2004 -2004
  • 電極/有機分子完全コンジュゲート系の有機合成的手法による実現
    2004 -2004
  • 共役拡張分子の新合成とエレクトロニクスへの応用
    2003 -2003
  • 電極/有機分子完全コンジュゲート系の有機合成的手法による実現
    2003 -2003
  • 共役拡張分子の新合成とエレクトロニクスへの応用
    2002 -2002
  • 電極/有機分子完全コンジュゲート系の有機合成的手法による実現
    2002 -2002
  • New synthesis of conjugation-expanded molecules and their application for electronic devices
    2002 -2002
  • 前駆体型有機エレクトロニクス材料の開発

MISC

Industrial Property Rights

Awards & Honors

  • 1989/11 有機合成協会中国四国支部 有機合成協会中国四国支部奨励賞
     JPN 
    受賞者: 宇野 英満
  • 1989 Aword of Synthetic Organic Chemistry Chugoku-Shikoku Division
  • 1984/07 野津奨励賞
     
    受賞者: 宇野 英満

Research Grants & Projects

  • Construction of optically-active distorted pi-conjugated systems and their properties
    Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
    Date (from‐to) : 2019/04 -2023/03 
    Author : 宇野 英満
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    Date (from‐to) : 2013/06 -2018/03 
    Author : TADA Hirokazu
     
    We promoted joint studies by researchers in molecular design / synthesis, surface physics, molecular nanotechnology, semiconductor physics, information technology and theoretical physics, and published 591 papers on the following topics: (1) Precise design of molecules and molecular aggregates, (2) Structure and electronic state molecules on various electrodes, (3) Guiding principles for single molecular junctions showing nonlinear / asymmetrical current-voltage characteristics and switching characteristics by electric and magnetic field, and (4)Preparation of stochastic resonance devices utilizing the inherent noise of the element and the self-pulsating induced by voltage application. These results greatly contribute to progress in the field of single molecular electronics and open up research strategies on novel memory and computing systems based on molecular networks.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    Date (from‐to) : 2013/06 -2018/03 
    Author : Uno Hidemitsu, MORI Shigeki, OGAWA Takuji, IE Yutaka, SUGIMOTO Nobuaki
     
    Electric measurement of single molecules which pi-systems were altered by external stimuli such as heat, light, acid, etc. was planned. Bicyclo[2.2.2]octadiene ring system was chosen as such an external-stimulus-changeable moiety and porphyrin, and hexapyrrolohexaazacoronene (HPHAC) were chosen as such pi-systems. In bisthiaporphyrins fused with BCOD and benzene rings, their macrocyclic ring current routes were altered from on a long axis to on short axes by protonation.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    Date (from‐to) : 2013/04 -2014/03 
    Author : 宇野 英満
     
    「2,5-シクロヘキサジエン-1,4-ジラジカルの生成とその応用研究」の採択を受けて、当初予定していた下記3課題の解決に取り組んだ。 課題① ピロロ[3,4-f]イソインドール前駆体の分解挙動とその生成物分析 課題② ピロロ[3,4-f]イソインドール–金属カルボニル錯体の合成 課題③ チオフェノ[3,4-f]イソインドール前駆体及びチオフェノ[3,4-f]イソチアナフテン前駆体の合成と反応およびその物性とそれらを用いた新奇π電子系化合物の合成 9-ヒドロキシ-4,8-メタノピロロ[3,4-f]イソインドールの酸化反応ではポリマーしか生成しない事がすでに判明していたので、この化合物のピロール窒素をメチル保護し、Parikh-Doeling酸化することでカルボニル架橋体を得て、熱挙動及び光分解挙動を検討するための合成を開始した。7-tert-ブトキシノルボルナジエンより誘導したジエチル=9-ヒドロキシ-4,8-メタノピロロ[3,4-f]イソインドール-1,7-ジカーボキシレートを、NaHで処理ののちヨードメタンと反応させることによりN,N-ジメチル体を得た。これをParikh-Doeling酸化すると、徐々に分解反応が進行し混合物が得られた。この混合物の構造解析をしているところで、補助金事業の中止が決定した。当該申請のプロジェクトは、今後他の補助金事業により継続していくこととしている。
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
    Date (from‐to) : 2011/04 -2014/03 
    Author : UNO Hidemitsu, MORI Shigeki, OKUJIMA Tetsuo, YAMADA Hiroko, KOBAYASHI Nagao
     
    We investigated synthesis of pi-system-fused porphyrin oligomers, bisthiaporphyrin, cyclo[n]pyrroles, picenes, [5]helicenes, bisBODIPYs, and naphth[2,3-f]isoindoles mainly based on the pericyclic cycloreversion as the key step and analyzed their electronic properties. The two-photon absorption property of pi-system-fused porphyrin oligomers is proven to be affected not by the numbers but mostly by the shapes of their pi systems. Stable bisBODIPYs bearing strong absorptions only in the NIR region have been explored.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
    Date (from‐to) : 2011/04 -2014/03 
    Author : KOMATSU Naoki, UNO Hidemitu, MORI Shigeki
     
    We have been developing the methodology to discriminate the handedness and diameter of single-walled carbon nanotubes (SWNTs) through molecular recognition using chiral diporphyrin nanotweezers. Although relatively small diameters of SWNTs (less than 1.0 nm) were recognized well, nanotweezers were not able to form stable complexes with the SWNTs with the diameters larger than 1.0 nm. In this context, we designed chiral diporphyrin with much larger cavity; namely "nanocalipers". As expected, we obtained optically active SWNTs with more than 1.0 nm in diameter and, unexpectedly, enriched metallic SWNTs over semiconducting ones. The optically active metallic SWNTs are identified for the first time, in addition to the optically active semiconducting SWNTs with such large diameters. Higher selectivity to metallic SWNTs are observed in the case of pyrene-based nanocalipers.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    Date (from‐to) : 2011/04 -2013/03 
    Author : 宇野 英満
     
    申請者は,逆Diels-Alder反応によりπ電子系を融合させる方法を開発し,「ペリ環状分解反応による新しいπ電子系化合物の創出と有機電子機能材料への応用」関する研究を強力に推進してきた.今年度の研究では、1.7-オキソビシクロ[2.2.1]ヘプタジエン縮環ピロールの分解挙動の検討,2.二重混乱フロリン誘導体の物性検討,3.ベンゼン環構造を大環状共役系内に有する物質の合成,4. 近赤外色素の合成を行った. 1.の課題では7-オキソビシクロ[2.2.1]ヘプタジエンによりピロールとナフタレンの縮環した化合物の熱及び光による分解挙動を検討したところ,逆Diels-Alder反応の起こらない系でも反応が速やかに進行することが判明した.7-オキソビシクロ[2.2.1]ヘプタジエン縮環ジピロールでは,プロトン移動が起こると速やかに分解が進行することが判明した.2.の課題では,二重混乱フロリン錯体の合成を検討したが,環内径が小さいため錯体は得ることができなかった.3.の課題については,現在も継続中であるが7-オキソビシクロ[2.2.1]ヘプタジエン骨格で両端をつないだπ電子系の構築を行っている.4.の課題では,近赤外にのみ吸収を有するBisBODIPYの合成に成功した.現在は応用に向けて,JSRおよび日本触媒と共同で研究を進めている. また,本領域班員の谷文都九州大学准教授とは,フラーレン類とポルフィリン二量体の包摂挙動についての共同研究を行い,種々の包接錯体の結晶構造を明らかにした.本領域班員の小林長夫東北大学教授とは,フロリンの電子線スペクトル解析において共同研究を行った。
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research
    Date (from‐to) : 2011 -2012 
    Author : UNO Hidemitsu, OKUJIMA Tetsuo, MORI Shigeki, YAMADA Hiroko, KOBAYASHI Nagao
     
    Highly conjugated organic compounds absorbing near-infrared light are essential materials for improvement of organic photovoltaic cells. In this study, we synthesize dyes with a novel skeleton bearing near-infrared absorption and investigate their electronic properties as well as potentials for organic photovoltaic-cell materials by the solution-processed fabrication of their precursors. When the two-dimensional πsystems such as porphyrins are fused with a benzene unit, there must be two major transitions: a longitudinal transition directed along the fused rings and short transitions due to the individual porphyrin rings. Therefore, strong absorption remains in a visible region, even if the absorption with the longest wavelength reaches to the near-infrared region. On the other hand, the πsystem of boron-dipyrromethene (BODIPY) spreads one-dimensionally and has one strong absorption band at ca. 500 nm. We succeeded in the synthesis of bisBODIPY dyes having absorption only in the near-infrared region due to the longitudinal transition by fusion of the BODIPY chromophores in the longitudinal fashion. In addition, we succeeded inthe preparation of stable near-infrared dyes under air by introduction of electron-withdrawing groups. Now, the application studies for near-infrared specific filters, organic photovoltaic cells, etc. are underway in the cooperative companies.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
    Date (from‐to) : 2010 -2012 
    Author : YAMADA Hiroko, NAKAYAMA Ken-ichi, UNO Hidemitsu, OKUJIMA Tetsuo
     
    In order to confirm therelevance of the photoprecursor method, the preparation procedure of organic field effect transistor (OFET)devices of pentacene by the solution processof the photoprecursor of pentacene (PDK) followed by the photoirradiationwas optimized. The best FET mobility was 0.86 cm2V-1s-1, which is one of the best perforamance of pentacene prepared by the thermal-or photo-precursor methods. Furthermore a various new acene filmswereprepared usingthe photoprecursor method andthe correlation between the compound structures, the film structures, and the photovoltaic performances were investigated in detail.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    Date (from‐to) : 2009 -2010 
    Author : 宇野 英満
     
    申請者は、逆Diels-Alder反応によりπ電子系を融合させる方法を開発し、さまざまな高共役π電子系化合物の合成に成功してきた。この方法を用いてベンゼン環を内部や環系に融合した拡張ポルフィリン類の合成や様々な新規π電子系の構築に挑戦した。いかに結果を記す。 1.前年までの研究でジヒドロビシクロ[2.2.2]オクタジエン(BCOD)渡環ヘキサフィリンを0.2%の収率で得ることに成功している。この収率向上のための条件検討を行ったが、良い条件を見つけるには至っていない。現在置換パターンを変えたもので合成の検討を行っている。 2.BCOD環連結ジピロールは、アセトキシメチルピロールと反応することにより、ビス(ジピロメタン)とすることができた。これをアルデヒドと反応させることにより二重NC反転フロリンの電子系をもつ化合物の合成に成功し、この化合物の熱挙動を検討したが、逆Diels-Alder反応は進行しなかった。分解の条件を変えるために、7-オキソビシクロ[2.2.1]ヘプタジエン縮環ジピロールを合成したところ、室温でも容易に分解した。現在この骨格を有する二重NC反転フロリンの合成を行っている。 3.BCODで連結されたBODIPY色素を加熱すると、容易にπ電子系の融合したBisBODIPYを合成することに成功した。この新しい色素は、近赤外に強い吸収を持つが、可視領域にはほとんど吸収を持たないことが分かった。近赤外選択的フィルター用の色素として大変有望であることが分かった。 4.ポルフィセンやトリフィリンなどのポルフィリノイド色素の合成法を開発した。
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
    Date (from‐to) : 2008 -2010 
    Author : UNO Hidemitsu, YAMADA Hiroko, OKUJIMA Tetsuo, KOBAYASHI Nagao, MORI Shigeki, KIM DongHo
     
    I have explored the methodology for synthesis of highly conjugated compounds applying the pericyclic cycloreversion of the precursors in the final step such as thermal retro-Diels-Alder reaction and photo de-thiocarbonylation. These precursors are easily purified due to high solubility toward common solvents and high stability toward oxidation. The targeted highly conjugated compounds can be obtained in a highly pure form by the thorough purification of the precursors. I have developed this methodology, prepared the π-fused compounds, and then clarified their intrinsic properties.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
    Date (from‐to) : 2008 -2010 
    Author : KOMATSU Naoki, UNO Hidemitu, BAURI Ajoy Kumar
     
    Since the electrical and optical properties of SWNTs are closely correlated to their structures, structural control of SWNTs is important for their applications. Therefore, we have been developing host-guest methodology to separate single-walled carbon nanotubes (SWNTs). In this study, we designed and synthesized chiral diporphyrin nanotweezers consisting of two chiral porpyrins and rigid spacer in between, and applied them to selective extraction of SWNTs, realizing high selectivity to the diameter and handedness of SWNTs.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)
    Date (from‐to) : 2005 -2007 
    Author : UNO Hidemitsu
     
    Highly p-conjugated compounds have attracted great attention as highly functional organic materials such as field-effect transistors and sensors. However, there are many cases that fundamental properties of these compounds such as electronic and optical properties are unknown due to the difficulty of their preparation. I planned to solve this problem by developing highly pure synthesis of these largely π-conjugated compounds based on the pericyclic cycloreversion reactions in the final synthetic stages. First, I planned to prepare the soluble pentacene precursors bearing removable bridging parts at the 6,13-positions in pericyclic cycloreversion reactions initiated by heat or light, because pentacene derivatives were reported to show high electron mobility in FET devices. By using these precursors, I succeeded in pentacene FET device preparation by Tin-coating the precursors on substrates followed by the cycloreversion to pentacene derivatives. Second, I explore the synthon of very unstable isoindoles, namely bicyclo[2.2.2]octadiene-fused pyrroles, which quantitatively gave the isoindole derivatives via the cycloreversion by heat. This synthon opened the synthetic utility of isoindoles, which could have not been applicable for synthetic purpose. Starting from these synthons, I succeeded in preparation of porphyrinoids with novel is-systems and π-system-fused porphyrin oligomers. In these multi-step cycloreversion reactions of the precursors, the intermediary molecular structures were very important and the pericyclic cycloreversion reactions occurred sequentially. The precursors were proved to have a large cavity between the porphyrin rings and show a good molecular recognition with the fairly rigid cavities. For an example, they can distinguish the molecular sizes of fullerenes such as C60 and C70. I explored a new synthesis of 4,5,6,7-tetrafluoroisoindole which was one of the stable isoindoles bearing no substituent on the five-membered ring. I succeeded to rationalize the remarkable stability of 4,5,6,7-tetrafluoroisoindole by its X-ray crystallographic analysis and employ the compound for the synthesis of a variety of highly π-conjugated compounds.
  • 電極・有機分子完全コンジュゲート系の構築
    JST戦略的創造研究推進制度(研究チーム型) (戦略的基礎研究推進事業:CREST)
    Date (from‐to) : 2002 -2007
  • Preparation of Completely Conjugated Electrodes with Organic Compounds
    JST Basic Research Programs (Core Research for Evolutional Science and Technology :CREST)
    Date (from‐to) : 2002 -2007
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Priority Areas
    Date (from‐to) : 2005 -2005 
    Author : 宇野 英満
     
    本研究では海綿動物や海藻類など,未利用の海洋生物を対象として生物活性物質の探索研究を行ってきた.本年度は,愛媛県佐田岬の三崎漁協の協力により,水深200m付近より採集した7種の海綿動物ついて探索研究を展開した.これまでに分析を行った物質について以下に報告する. 本年度は,マウスリンパ性白血病細胞P388に対する活性および抗菌・抗カビ活性を指標として機能分子の探索研究を行った.その結果,一種類の抽出液に非常に強力な活性が認められた.活性を指標として精製を進めた結果,分子量1009,IC_<50>>0.1ng/mlを示す分子を見出した.本物質は,高速液体クロマトグラフを用いて分離した3画分が互いに異性化する分子であった.各種NMRスペクトルの解析を進めたところ,本物質はカリキュリンA^<1)>であった.この他の画分からも分子量1000を越える物質が確認しているが,これまでのところカリキュリンアミドAを始めとするカリキュリン類であると考えている.現在,微量同族体の分離と詳細な構造の解析を進めている. さらに別の海綿動物の抽出液について質量分析を試みたところ,一臭化物および二臭化物の分子イオンピークを観測した.質量分析を指標として分析を進め,マンザシジン類およびジブロモファケリンを単離した.さらに分析を進め,新規化合物であるジブロモジヒドロファケリンとジブロモジヒドロイソファケリンを単離し,その平面構造を明らかとした.現在のところ,さらなる微量同族体の分離と共に立体化学の解析を進めている.また,本物質については共に約70mgを得ており,他の活性試験に供することを検討している.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Exploratory Research
    Date (from‐to) : 2003 -2004 
    Author : 宇野 英満
     
    共役系の広がった有機色素化合物は、光電子材料や分子素子などとして大変注目を集めている。本課題の研究では、高度に共役系の広がった有機色素化合物の合成に際し、精製容易な前駆体化合物を合成し、これを最終段階で逆Diels-Alder反応を起こさせることで、これまで精製上の問題から高純度のものが得られなかった色素剤を高純度高効率的に合成する手法を開発した。この方法を利用して、ビシクロオクタジエン縮環ポルフィリンの熱分解により除去されるエチレン部分を修飾することで、熱分解温度の制御を目指した。まずヒドロキシル基を2つ導入しただけでは分解温度にさほど変化はなかったが、これを強アルカリやアルミナと処理することで、室温以下でテトラベンゾポルフィリンに変換することに成功した。これについては、すでに論文発表をおこなっているが、そのほかの置換基を有するものについての熱分解反応を検討したところ、イソプロピリデンジオキシ基を有するものに関しては、分解温度が、約30度上昇することを見出した。また、チオインジゴの逆Diels-Alder反応前駆体の合成を達成し、この前駆体は加熱によりP21/cの結晶形のチオインジゴに定量的に変化することを見出した。市販のチオインジゴはP21/nの結晶系であることから、チオインジゴを可溶化しただけでなく、固体の結晶系についても制御することに成功したことになる。この反応を、TG-XRDで詳細に検討したところ、前駆体の結晶相は、チオインジゴP21/c結晶相に直接なるのではなく、中間に別の結晶相を経ていることが明らかになった。これは、エチレンが一分子だけ脱離した化合物の結晶相であると考えられるが、現在詳細を検討中である。
  • 複素環化合物の新規合成法の開発
    Date (from‐to) : 2004
  • 高共役π電子系化合物の高純度合成法の開発とその物性
    Date (from‐to) : 2004
  • Study on novel synthesis of heterocyclic compounds
    Date (from‐to) : 2004
  • Synthesis and properties of highly pure and pi-conjugated compounds.
    Date (from‐to) : 2004
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
    Date (from‐to) : 2000 -2002 
    Author : UNO Hidemitsu, SAKANAKA Masahiro
     
    Recently, compounds with an anthraquinone skeleton have been reported to have many interesting activities such as neuronal cell-protecting activity (espicufolin), anti-helpetic activity (AH-1763 IIa), and carbon clearance activity (SS43405E). We planned not only to prepare the bioactive anthraquinones and their analogs, but also to create highly active compounds by elucidation of their in vivo action mechanisms on neuronal cells. In this research, we achieved the synthesis and absolute structure determination of espicufolin, the synthesis and absolute structure determination of SS43405E, and establishment of the synthetic routes to dihydroxyanthraquinones represented by K1115A. Racemic and S-espicfolins were subject to bioassay by using mouse embryonic neuronal cells. The espicufolins showed no protecting activity for the toxicity of glutamate but weak cytotoxiciry to the cells employed. In the synthetic approach for antihelpetic AH-1763 IIa, two different routes were examined, but total synthesis has not been achieved, yet. We now intended to prepare the side chain of AH-1763 IIa by asymmetric aldol condensation.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Priority Areas (A)
    Date (from‐to) : 1999 -1999 
    Author : 宇野 英満, 椚 章
     
    種々のトリフルオロメチル置換オレフィンやフルオロメチルスルフィドの合成素子としての有用性を確立するために、電解による変換反応を検討した。硫黄ー炭素混合電極を陰極に用いて電解する方法は、効率よくS_8^<2->,S_6^<2->,S_3^-等の化学種を発生できることが報告されている。この方法を用いてα-スルホニルシンナモニトリル誘導体を電解するとイソチアゾール誘導体が生成することを見出した。 この手法をトリフルオロメチル基を有するアクリロニトリル誘導体1に対して用いると、ビスイソチアゾールではなくイソチアゾール環とジチオール環を有する2が生成した。一方、スルホニル基の代わりに塩素を有する化合物3を同様に処理したところ、2の様なタイプの化合物は生成せずチイラノチオフェン4が生成した。また、アクリル酸誘導体5で行うと加硫化還元された生成物6を与え、本反応が基質オレフィンの還元電位と立体障害により主生成物が大きく変わることを見いだした。パラアルキル置換フェノール類を塩基性条件下二塩化硫黄と処理すると興味深い錯形成能を有するチアカリックス[4]および[6]アレーンが生成することが報告されている。4位にペルフルオロアルキル鎖を持つフェノール7は、ベンゾキノンから容易に合成できるため、ペルフルオロアルキル鎖を有するチアカリックスアレーン類の合成を目指して検討を行った。 ペルフルオロアルキルチアカリックスアレーン合成の予備実験として7a(R=t-Bu)及び7b(R=CH_2CH_2C_6F_<13>)を基質とし、硫黄ー炭素混合電極を陽極に用いて加硫化反応を行った。しかしながら支持電解質等の条件を変えて反応を行っても、原料が回収されるか、複雑な反応混合物が得られたに過ぎず、生成物の単離構造決定には到っていない。
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Priority Areas (A)
    Date (from‐to) : 1999 -1999 
    Author : 小川 琢治, 宇野 英満
     
    単分子で高い電導性を示す分子ワイヤーは、分子エレクトロニクス素子の重要な構成要素である。一般的に分子はトンネリングにより電気を通すと考えられており、トンネリング抵抗はエネルギーギャップが小さいほど低い。半経験的分子軌道計算を行った結果、アンチモンやビスマスなどの重たい第15族元素のポルフィリンやN-混乱ポルフィリンは、かなり小さなエネルギーギャップを持つことがわかった。 中でもビスマスは低いエネルギーギャップを持つ可能性があるが、これまでに5価のビスマスポルフィリンは知られていなかった。そこで3価のビスマスポルフィリンの電気化学酸化を試みた。第1酸化電位で定電位酸化を行い、得られた化合物の吸収、NMR、エレクトロンスプレーマススペクトルなどの結果からは、5価のビスマスポルフィリンが得られたと思われたが、安定性に欠け確認できなかった。更に安定なビスマスポルフィリンを得るために各種置換基を持つポルフィリンや大きな内孔を持つヘキサフィリンを合成しビスマスを導入後、電気化学酸化を行ったが安定な化合物を得るには至らなかった。 N-混乱ポルフィリンに第15族元素が入った場合、もしこれが3価のアニオンとして働くと中心元素は中性となり、2価のアニオンとして働くとカチオンになる。臭化アンチモンとの反応で得られた生成物のX線単結晶解析を行ったところ中性の5価化合物であることが確認できた。この化合物は、対応するアンチモンポルフィリンよりも長波長に吸収を持っている。電気化学測定において、アンチモンN-混乱ポルフィリンはアンチモンポルフィリンよりも第1酸化電位と第1還元電位の差が小さかった。これらの実験結果から、アンチモンN-混乱ポルフィリンは、対応するアンチモンポルフィリンエネルギーギャップが低いことが明らかとなった。また、軸配位子交換も容易であった。この性質を利用し長い分子ワイヤーを合成可能である。
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
    Date (from‐to) : 1998 -1999 
    Author : KUNUGI Akira, UNO Hidemitsu
     
    Sulfur-containing organic compounds could be transformed to an aimed compound by applying the fruitful sulfur chemistry. Therefore, it is interesting to study incorporation of sulfur functionality into the organic compounds using a reactive sulfur-graphite electrode (S-C electrode). In the present work, we carried out introducing of sulfur functionality into the following compounds : cumulenes havingtrifluoromethyl groups, phenylsulfonylpropennitriles, and phenylsulfonylpropennitriles having a trifluoromethyl group. The present work leads to the following conclusions. (1) Electroreduction of cumulenes with trifiuoromethyl groups using the S-C electrode afforded dimeric compounds with a 1,2,5,6-tetrathiocin skeleton as the major products. There was a large difference in the main product between the cumulenes with and without trifluoromethyl groups, cumulenes without trifluoromethyl groups yielding 7-membered ring compounds with five sulfur atoms such as pentathiepins. (2) 3-Aryl-2-phenylsulfonylpropenenitriles having geminal cyano and sulfonyl groups gave dimeric 5-arylisothiazoles bridged with two or three sulfur atoms at the 3-position in moderate yields. 2-Phenyl-3-phenylsulfonylpropenenitrile havingvicinal cyano and sulfonyl groups yielded dimeric 4-phenylisothiazole bridged with two sulfur atoms together with 3-[(Z)-2-cyano-2-phenylethenylthio]-5-phenylisothiazole. This electrosynthesis of sulfur-containing compounds is characterized as elimination of a phenylsulfonyl group accompanying the addition of polysulfide anion(s) produced by electroreduction of elemental sulfur. (3) 2-(4-Biphenylyl)-3-phenylsulfonyl-3-trifluoromethylpropenenitrile afforded a coupling compound bridged with a nitrogen atom of isothiazole and 1,2-dithiolane skeleton.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
    Date (from‐to) : 1997 -1999 
    Author : UNO Hidemitsu
     
    In order to develop a method for preparation of bioactive seine derivatives from glutamic acid as a chiral source, stereoselective alkylation of (3R)-5-TBSoxy-3-phenyl-1H-pyrrolo[1,2-c]oxazole (1) has been investigated. Before the investigation, stereoselectivity in the reaction of TBSOP (N-t-butoxycarbony1-2-t-butyldimethylsiloxypyrrole) with aldehydes was examined as the model reaction. In the presence of boron trifluoride etherate, TBSOP reacted with aromatic aldehydes preferrably to give threo products, while erythro products were mainly obtained in the presence of tin tetrachloride. The comlpetely reverse selectivity was observed in the reaction of TBSOP with aliphatic aldehydes. This selectivity could be reasonably explained by considering the transition states, similar discussion of which could be expanded to the reaction of 1 with aldehydes. Next, the reaction of 1 with nitroethylene was carried out to give the product which was derived from the same face attack of nitrcethylene with the 3-phenyl group. On the other hand, the opposite face-attacked product was preferrably obtained in the reaction with other nitro olefins. The nitro group was removed from these major products in good yields. The products were successfully transformed to the aimed alpha-alkylserine derivatives via dihydoxylation with osmium tetroxide followed by the lactam ring cleavage with lead tetraacetate. In order to prepare thermozymocidin and ISP-I, double stereoselection in the reaction of 1 with chiral glyceraldehyde derivative was investigated. In the presence of titanium tetrachloride, the reaction of 1 with R-2-TBSoxy-propionaldehyde gave the desired product which had the required stereochemistry for thermozymocidin in 55% yield. On the other hand, the reaction of I with (S)-2-TBSoxy-propionaldehyde in the presence of zinc chloride gave the product with the required stereochemistry for ISP-I in 60% yield. This method was proved to be applicable for introduction of required stereochemistries for thermozymocidin and ISP-I and the adducts were successfully converted to the basic skeleton of thermozymocidin and ISP-I by the similar method described above.
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Priority Areas (A)
    Date (from‐to) : 1998 -1998 
    Author : 宇野 英満, 椚 章
     
    種々のトリフルオロメチル置換オレフィンやフルオロメチルスルフィドの合成素子としての有用性を確立するために、電解による変換反応を検討した。トリフルオロメチル基とスルホニル基を有するオレフィンをプロトンドナー存在下に反応を行うと単に脱硫化生成物のみが得られるが、陽極にMgを用いるとhead-to-headカップリングの後、部分脱フッ素化が起こり、フルオロシクロペンテン誘導体が収率よく生成した。 次に、硫黄炭素混合電極を陰極に用いて電解する方法を検討した。トリフルオロメチル基を有するクムレンを基質に用いて反応を行うとクムレン炭素への付加反応が起こり、8員環化合物1,2,5,6-テトラチオシン誘導体を収率よく与えた。一方、テトラアリールクムレンは同条件下で7員環化合物1,2,3,4,5-ペンタチエピンを優先的にあたえた。トリフルオロメチル基を有するジブルモメチレン誘導体を電解還元すると、収率よくモノ臭素化物の異性体混合物を与える。この電解反応においては、プロトンドナーが存在していない場合でも同様の結果を与え、FBWタイプの転位反応や、アルキリデンカルベンの二量化反応などは全く見られなかった。硫黄・炭素混合電極で処理すると中間体としてチオケテン等価体が生成し、これがさらに反応したと考えられる様々な含硫黄複素環化合物を与えることを見いだした。
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Priority Areas (A)
    Date (from‐to) : 1998 -1998 
    Author : 小川 琢治, 宇野 英満
     
    (1)5価ビスマスポルフィリンの研究 アンチモンまでの第15族の軽い元素のポルフィリンは一般に5価の状態が安定で、3価の化合物は空気酸化されて5価になる。ところが、唯一ビスマスポルフィリンだけは3価の化合物しか知られておらず、5価の化合物は合成不可能と思われていた。3価のビスマスポルフィリンを電気化学的に酸化すると新しい化合物が得られ、その種々のスペクトルデータからこの化合物が5価のビスマスポルフィリンではないかと考えている。この化合物の、安定性を支配する要因を研究したところ、以下のことが判った。 ・ 酸素が存在しないと、プロトン性溶媒中でもこの化合物は非常に安定である。 ・ 電子供与性基をポルフィリンに導入しても安定化には寄与しない。 ・ コア半径の大きなポルフィリンを用いても安定化には寄与しない。 (2) 第15族元素N-混乱ポルフィリンの合成 第15族元素N-混乱ポルフィリンは以下の性質から、分子スケールエレクトロニクスに置ける分子ワイヤーとして有望な化合物である。 ・アキシャル位に結合を延ばすことができる。・ポルフィリンと異なり、中心元素が中性となリアニオンが存在しないためHOMO-LUMOギャップが小さくなる。・芳香族性が弱まる可能性が有り、HOMO-LUMOギャップが小さくなる。 アンチモンN-混乱ポルフィリンを合成し、そのX線構造解析や電気・光特性を調べた結果、期待通りに中心元素が中性であること、小さなHOMO-LUMOギャップを持つことが確認できた。また、軸配位子が容易に交換可能であるため、この性質を利用して分子ワイヤーを作ることが可能である。 また、リンN-混乱ポルフィリンも合成し、軸配位子は(=O)で有ることが判った。
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research on Priority Areas
    Date (from‐to) : 1997 -1997 
    Author : 小川 琢治, 宇野 英満
     
    1)5価ビスマスポルフィリンの研究: アンチモンまでの軽い元素のポルフィリンは一般に5価の状態が安定で、3価の第15鉄元素ポルフィリンは空気酸化されて5価になることが多い。ところが、唯一ビスマスポルフィリンだけは3価の化合物しか知られておらず、5価の化合物は合成不可能と思われていた。Bi(III)-TPP(No_3)(1)のCVスペクトルは、銀標準電極に対して+844,+962mVにピークを持つ半可逆の酸化波を示した。そこで、900mVで定電位電解を行いながら可視吸収を測定すると、1の470nmのソーレー帯の吸収が減少し442nmの吸収が増大した。この吸収の変化はSb(III)TPPがSb(V)TPPに酸化されるときの変化と非常に類似している。完全に470nmの吸収が消失した後、生成物を単離し黄緑色の固体(2)を得た。CV,UV,NMRの結果から、化合物2は5価のビスマスポルフィリンである可能性が高い。 (2)第15族元素N-混乱ポルフィリンの合成: N-混乱ポルフィリンは、ポルフィリンのピロール環のひとつが反転して窒素原子がβ-位に位置しているポルフィリン異性体の1種である。従来の第15族元素ポルフィリンではポルフィリン環が2価の配位子であるため、中心の第15族元素はカチオン状態となり対アニオンを持たざるを得ない。ところが、N-混乱ポルフィリンは構造上二価・三価のどちらの配位子としても働く可能が有り、電荷的に中性の第15族元素ポルフィリン類縁体得ることができる。Sb(V)(OMe)_2-N-混乱ポルフィリンを合成し、その単結晶X線結晶解析をおこなったところ対アニオンが無いことから、N-混乱ポルフィリンは三価の配位子として働いており中性の分子であることが確認できた。
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for General Scientific Research (C)
    Date (from‐to) : 1995 -1995 
    Author : 宇野 英満
     
    ターゲットとしていたラクタシスチン類縁体のうち、側鎖がヒドロキシベンジルとなっている化合物1の合成を完了し、昨年12月に開かれた環太平洋化学会議で発表した。しかし最終生成物の量は3mgであり、現在生理活性試験に出せるだけの量を合成しているところである。 我々の合成経路の重要中間体である(3S)-3-フェニル-5-(t-ブチルジメチルシロキシ)-6-メチル-1H-ピロロ[1、2-c]オキサゾール(2、シロキシピロール2)とベンズアルデヒドの反応は、イソブチルアルデヒドとの反応の時の立体選択性と全く異なる結果が得られた。ルイス酸として三フッ化ホウ素を用いると望む立体化学と完全に反対の絶対配置を持つ異性体が主に生成した。四塩化スズを用いて反応を行っても選択性は低いものの同じ異性体が主生成物として得られた。構造に関してはX線結晶構造解析により最終に決定した。この問題を解決するためにシロキシピロール2の3位エナンチオマーであるシロキシピロール3で合成を行う事とし、L-グルタミン酸から化合物3を合成した。化合物3とベンズアルデヒドとの反応で望む立体化学を持つ4を得た後、ラクタシスチン合成の経路と同様の経路で目的物1とした。 この合成経路で用いたシロキシピロール類とアルデヒドとの反応は、ルイス酸のみならずアルデヒドの種類が変わっても、反応の面選択性が変化するというたいへん興味深いものである事が分かった。現在この面選択性に寄与する因子を解明すべく、種々のシロキシピロール及びそのリチオ誘導体と親電子試剤の反応を検討中であり、結果については3月下旬に開かれる日本化学会第70春季年会で発表予定である。
  • 含フッ素光学材料の合成
    官民連帯共同研究
    Date (from‐to) : 1993
  • 機能性色素の合成研究
    Date (from‐to) : 1993
  • Synthesis of Fluoro-organic Compounds for Optical Materials
    Public/Private Cooperative Joint Researches
    Date (from‐to) : 1993
  • Synthetic Study on Functional Dyes
    Date (from‐to) : 1993
  • ポリフルオロアルキル鎖を有する機能材料の合成
    Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Encouragement of Young Scientists (A)
    Date (from‐to) : 1990 -1990 
    Author : 宇野 英満
  • Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Developmental Scientific Research (B).
    Date (from‐to) : 1989 -1990 
    Author : SUZUKI Hitomi, KITAHARA Katsuhiko, UNO Hidemitsu
     
    A variety of heteroaromatic amides having a general formula [1] Have been synthesized and their herbicidal activities examined. After extensive screening for paddy field herbicide, N-[alpha-(2-thienyl)-ethyl]-4-isopropylbenzamide [2] Was found to exhibit a high growth-inhibiting activity toward green and blue algae. A concise and economical four-step route to amide [2] has been developed starting from cumene and thiophene. A key step involves the direct three-component condensation of 4-isopropylbenzamide, thiophene and paraaldehyde in the presence of formic acid/phosphoric acid. A novel methodology for introducing perfluoroalkyl group directly into a variety of molecular frames has been developed and successfully employed to the synthesis of fluorine-containing heteroaromatic amides.
  • アントラサイクリン類の合成的研究
    Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research Grant-in-Aid for Encouragement of Young Scientists (A)
    Date (from‐to) : 1985 -1985 
    Author : 宇野 英満

Committee Membership

  • 2009 -2011   Synthetic Organic Chemistry   評議員   Synthetic Organic Chemistry

愛媛大学教員活動実績

教育活動(B)

担当授業科目(B01)

  • 2019, the first semester, under graduate, 有機化学Ⅱ
  • 2019, the first semester, under graduate, 卒業研究Ⅰ
  • 2019, the first semester, master course, 化学ゼミナールⅢ
  • 2019, the first semester, under graduate, 有機化学IIA


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