研究者データベース

菅原 卓也スガハラ タクヤ

所属部署名大学院農学研究科 生命機能学専攻
職名教授
Last Updated :2019/04/11

研究者基本情報

基本情報

氏名

  • 氏名

    菅原 卓也
  • 氏名(カナ)

    スガハラ タクヤ

基本情報

所属

所属・職名

  • 部署

    大学院農学研究科 生命機能学専攻 健康機能栄養科学特別コース
  • 職名

    教授

学歴等

学歴

  • 19930000, 九州大学, 農学研究科, 食糧化学工学専攻 博士課程修了
  • 19900000, 九州大学, 農学研究科, 食糧化学工学専攻 修士課程修了
  • 19880000, 九州大学, 農学部, 食糧化学工学科 卒業
  • 19930000
  • 19900000
  • 19880000

学位

  • 博士(農学)

その他基本情報

所属学協会

  • 日本黒酢研究会
  • 日本香辛料研究会
  • ノビレチン研究会
  • The INTERNATIONAL SOCIETY FOR NUTRACEUTICALS AND FUNCTIONAL FOODS (ISNFF)
  • 日本アレルギー学会
  • 日本フードファクター学会
  • 日本機能性食品医用学会
  • 日本食品免疫学会
  • 日本農芸化学会
  • 日本動物細胞工学会
  • 生物機能研究会
  • 日本食品科学工学会
  • 日本栄養・食糧学会

委員歴

  • 20180800, 99990000, Nプラス協議会, 会長
  • 20180400, 99990000, ノビレチン研究会, 幹事
  • 20150400, 99990000, 日本栄養・食糧学会, 参与
  • 20150400, 99990000, 日本動物細胞工学会, 幹事
  • 20120400, 99990000, 日本食品科学工学会, 評議委員
  • 20010000, 20020000, 日本農芸化学会, 中四国支部評議員, 日本農芸化学会
  • 20070400, 99990000, 日本農芸化学会, 中四国支部参与, 日本農芸化学会
  • 20010000, 20020000
  • 20070000, 20080000
  • 20110000, 20120000
  • 20090000, 20100000

経歴

  • 20160400, 99990000, 愛媛大学 大学院農学研究科(教授)
  • 20160400, 99990000, 愛媛大学(学長特別補佐)
  • 20130400, 99990000, 愛媛大学 農学部(センター長)
  • 20130200, 20160300, 愛媛大学 農学部(教授)
  • 20070400, 20130200, 愛媛大学 農学部(准教授)
  • 20060700, 20070300, 愛媛大学 農学部(助教授)
  • 20020200, 20021100, 米国テキサス大学ヘルスセンター
  • 19940100, 20060600, 愛媛大学 農学部(助教)
  • 20070000
  • 20060000, 20070000
  • 20020000
  • 19940000, 20060000

研究活動情報

研究分野等

研究分野

  • 農芸化学, 食品科学
  • プロセス・化学工学, 生物機能・バイオプロセス
  • 社会医学, 衛生学・公衆衛生学

研究キーワード

  • 抗炎症
  • オーラプテン
  • ノビレチン
  • ハイブリドーマ
  • 機能性食品
  • 抗体産生促進因子
  • モノクローナル抗体
  • 無血清培養
  • リゾチーム
  • TLR4
  • 構造活性相関
  • 抗アレルギー
  • 産生促進
  • アマニリグナン
  • サイトカイン産生
  • ヒト末梢血リンパ球
  • マクロファージ
  • 牛乳
  • 脂肪肝抑制
  • 脂肪蓄積抑制効果
  • 免疫促進効果
  • 自然免疫
  • アマニ
  • 脂肪蓄積抑制
  • JNK
  • プロテオースペプトン
  • セコイソラリシレジノール
  • 免疫調節
  • 抗ガン活性
  • ハイプリドーマ
  • 免疫促進
  • コラーゲン
  • 抗糖尿病効果
  • 細胞制御工学
  • 細胞生物学
  • 食品科学・栄養科学
  • 食品機能学
  • 環境毒性学

著書・発表論文等

論文

  • Inhibitory effect of aqueous extract of Cuminum cyminum L. seed on degranulation of RBL-2H3 cells and passive cutaneous anaphylaxis reaction in mice., M. Hada, K. Nishi, M. Ishida, H. Onda, S. Nishimoto and T. Sugahara, Cytotechnology, In press, 20190000
  • Lysozyme from hen egg white ameliorates lipopolysaccharide-induced systemic inflammation in mice, A. Tagashira, K. Nishi and T. Sugahara, Cytotechnology, In press, 20190000
  • Anti-allergy potential of petis extract on immunoglobulin E production by U266 cells, R.V. Tansy, A.B.N. Putra, T. Sugahara, Canrea Journal, 2, 2, 136, 142, 20181200
  • IgE production-suppressing effect of asam kandis (dried Garcinia xantochymus) extracts by mouse hybridoma aDNP-Hy Cells., N. Supardi, A. Sumarpo, R. Sutejo, A.B.N. Putra, N. Kageyama, M. Kawano and T. Sugahara, Biodiversitas, 19, 1, 330, 335, 20180100
  • Immunostimulatory effect of tempoyak (fermented durian) on inducing cytokine production (IL-6 and TNF- ) by RAW 264.7 cells., S. Susanto, A. Sumarpo, A.A. Parikesit, A.B.N. Putra, E. Ishii, K. Tabuchi and T. Sugahara, Biodiversitas, 19, 1, 318, 322, 20180100
  • Inhibitory effect of Japanese black vinegar on IgE-mediated degranulation of RBL-2H3 cells and a murine model of Japanese cedar pollinosis., S. Awane, K. Nishi, M. Ishida, M. Nagano, K. Hashiguchi, A. Fujiic and T. Sugahara, Cytotechnology, 70, 3, 961, 974, 20180600
  • Anti-inflammatory effect of lysozyme from hen egg white on mouse peritoneal macrophages., A. Tagashira, K. Nishi, S. Matsumoto, M. Ishida and T. Sugahara, Cytotechnology, 70, 3, 929, 938, 20180600
  • Immunomodulatory activity of octenyl succinic anhydride modified porang (Amorphophallus oncophyllus) glucomannan on mouse macrophage-like J774.1 cells and mouse primary peritoneal macrophages., S. Gurusmatika, K. Nishi, E. Harmayani, Y. Pranoto and T. Sugahara, Molecules, 22, 7, E1187, 20170700
  • Suppressive effect of ethanol extract from passion fruit seeds on IgE production., A. Mizusaki, K. Nishi, H. Nishiwaki, M. Ishida, T. Tamamoto and T. Sugahara, J. Funct. Foods, 32, 176, 184, 20170500, 10.1016/j.jff.2017.02.030
  • Immunostimulatory effect of dried bonito extract on mouse Macrophage cell lines and mouse primary peritoneal macrophages., M. Ishida, K. Nishi, K. Shinohara, N. Kunihiro, K. Osajima, T. Suemitsu and T. Sugahara, Cytotechnology, 69, 2, 229, 244, 20170400, 10.1007/s10616-016-0053-4
  • Effect of mandarin orange yogurt on allergic conjunctivitis induced by conjunctival allergen challenge., Y. Hara, A. Shiraishi, Y. Sakane, Y. Takezawa, T. Kamao, Y. Ohashi, S. Yasunaga and T. Sugahara, Invest. Ophth. Vis. Sci., 58, 7, 2922, 2929, 20170600
  • Suppressive effect of ethanol extract from mango (Mangifera indica L.) peel on IgE production in vitro and in vivo., M. Ishida, T. Sasaki, K. Nishi, T. Tamamoto and T. Sugahara, Biosci. Biotechnol. Biochem., 82, 4, 732, 739, 20180500
  • Syntheses of cytotoxic novel arctigenin derivatives bearing halogen and alkyl groups on aromatic rings., S. Yamauchi, T. Wukirsari, Y. Ochi, H. Nishiwaki, K. Nishi, T. Sugahara, K. Akiyama and T. Kishida, Bioorg. Med. Chem. Lett., 27, 17, 4199, 4203, 20170900, 10.1016/j.bmcl.2017.06.070
  • Immunostimulatory effect of aqueous extract of Coriandrum sativum L. seed on macrophages., M. Ishida, K. Nishi, N. Kunihiro, H. Onda, S. Nishimoto and T. Sugahara, J. Sci. Food Agr., 97, 14, 4727, 4736, 20171100, 10.1002/jsfa.8341
  • Efficacy of chlorophyll c2 for seasonal allergic rhinitis; single-center double blind randomized control trial., T. Fujiwara, N. Nishida, J. Nota, T. Kitani, K. Aoishi, H. Takahashi, T. Sugahara and N. Hato, Eur. Arch. Oto Rhino Laryngol., 273, 2, 4289, 4294, 20161200, 10.1007/s00405-016-4133-z
  • Immunostimulatory activity of snake fruit peel extract on murine macrophage-like J774.1 cells., S. Wijanarti, A.B.N. Putra, K. Nishi, E. Harmayani and T. Sugahara, Cytotechnology, 68, 5, 1737, 1745, 20161000, 10.1007/s10616-015-9925-2
  • Enantioselective syntheses of both enantiomers of 9'-dehydroxyimperanene and 7,8-dihydro-9'-dehydroxyimperanene and the comparison of biological activity between 9-norlignans and dihydroguaiaretic acids., S. Yamauchi, R. Tanimura, H. Nishiwaki, K. Nishi, T. Sugahara, M. Maruyama, Y. Ano, K. Akiyama and T. Kishida, Bioorg. Med. Chem. Lett., 26, 13, 3019, 3023, 20160700, 10.1016/j.bmcl.2016.05.020
  • Immunostimulatory effect of spinach aqueous extract on mouse macrophage-like J774.1 cells and mouse primary peritoneal macrophages., M. Ishida, S. Ose, K. Nishi and T. Sugahara, Biosci. Biotechnol. Biochem., 80, 7, 1393, 1402, 20160600, 0916-8451, 10.1080/09168451.2016.1146068
  • Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells., S. Yasunaga, M. Domen, K. Nishi, A. Kadota and T. Sugahara, J. Funct. Foods, 27, 406, 415, 20161200, 10.1016/j.jff.2016.09.025
  • Effect of the structure of dietary epoxylignan on its cytotoxic activity: relationship between the structure and the activity of 7,7'-epoxylignan and the introduction of apoptosis by caspase 3/7., T. Wukirsari, H. Nishiwaki, K. Nishi, T. Sugahara, K. Akiyama, T. Kishida and S. Yamauchi, Biosci. Biotechnol. Biochem., 80, 4, 669, 675, 20160400, 10.1080/09168451.2015.1123603
  • Effect of concurrent administration of nobiletin and β-lactoglobulin on the symptoms of Japanese cedar pollinosis models in mice., S. Yasunaga, A. Kadota, T. Kikuchi, C. Kubo, K. Nishi and T. Sugahara, J. Funct. Foods, 22, 389, 397, 20160400, 10.1016/j.jff.2016.01.045
  • Inhibitory effects of enzyme-treated dried sardine extract on IgE-mediated degranulation of RBL-2H3 cells and a murine model of Japanese cedar pollinosis., S. Awane, M. Nakamoto, K. Nishi, K. Osajima, T. Suemitsu and T. Sugahara, RSC Advances, 6, 85718, 85726, 20160000, 10.1039/c6ra14967g
  • Effects of an equol-producing bacterium isolated from human feces on isoflavone and lignan metabolism in mice., Tamura M, Hori S, Nakagawa H, Yamauchi S, Sugahara T, J. Sci. Food Agr., 96, 9, 3126, 3132, 20160700, 0022-5142, 10.1002/jsfa.7490
  • Methoxychlor enhances degranulation of murine mast cells by regulating FcεRI-mediated signal transduction., Yasunaga S, Nishi K, Nishimoto S, Sugahara T, Journal of Immunotoxicology, 12, 3, 283, 289, 20150700, 1547-691X, 10.3109/1547691X.2014.962122
  • Jellyfish collagen stimulates maturation of mouse bone marrow-derived dendritic cells., A.B.N. Putra, K. Nishi, R. Shiraishi, M. Doi and T. Sugahara, J. Funct. Foods, 14, 308, 317, 20150400, 10.1016/j.jff.2015.02.008
  • Ishizuchi dark tea suppresses IgE-mediated degranulation of RBL-2H3 cells and nasal rubbing behavior of pollinosis in mice., M. Kondo, K. Nishi and T. Sugahara, J. Funct. Foods, 14, 659, 669, 20150400, 10.1016/j.jff.2015.02.045
  • Acute larvicidal activity against mosquitoes and oxygen consumption inhibitory activity of dihydroguaiaretic acid derivatives., Nishiwaki H, Tabara Y, Kishida T, Nishi K, Shuto Y, Sugahara T, Yamauchi S, Journal of agricultural and food chemistry, 63, 9, 2442, 2448, 20150300, 0021-8561, 10.1021/jf504816a
  • Revised stereochemistry of ficifolidione and its biological activities against insects and cells., Nishiwaki H, Fujiwara S, Wukirsari T, Iwamoto H, Mori S, Nishi K, Sugahara T, Yamauchi S, Shuto Y, Journal of natural products, 78, 1, 43, 49, 20150100, 0163-3864, 10.1021/np5006746
  • Gene transfection into HeLa cells by vesicles containing cationic peptide lipid., Y. Ohama, Y. Heike, T. Sugahara, K. Sakata, N. Yoshimura, Y. Hisaeda, M. Hosokawa, S. Takashima and K. Kato, Biosci. Biotechnol. Biochem., 69, 8, 1453, 1458, 20150000, 10.1271/bbb.69.1453
  • Isoflavone changes during fermentation of kerandang (Canavalia virosa) milk using Lactobacillus plantarum-pentosus and its anticancer activity., D.T. Farianti, T. Sugahara, E.S. Rahayu, M.N. Cahyanto , U. Santoso and K. Nishi, Agriculture and Natural Resources, 49, 441, 450, 20150000
  • Activation of J774.1 murine macrophages by lactate dehydrogenase., Daifuku M, Nishi K, Okamoto T, Sugahara T, Cytotechnology, 66, 6, 937, 943, 20141200, 0920-9069, 10.1007/s10616-013-9646-3
  • The major whey protein -lactoglobulin inhibits IgE-mediated degranulation of RBL-2H3 cells and passive cutaneous anaphylaxis in mice., K. Nishi, M. Teranishi, S. Yasunaga, M. Iitsuka, S. Matsumoto and T. Sugahara, Int. Dairy J., 39, 1, 89, 95, 20141100, 10.1016/j.idairyj.2014.05.006
  • Studies on anti-allergic activity of Sargassum horneri extract., H. Yoshioka, M. Ishida, K. Nishi, H. Oda, H. Toyohara and T. Sugahara, J. Funct. Foods, 10, 1, 154, 160, 20140900, 10.1016/j.jff.2014.06.002
  • Cytotoxic activity of butane type of 1,7-seco-2,7'-cyclolignanes and apoptosis induction by Caspase 9 and 3., Wukirsari T, Nishiwaki H, Nishi K, Sugahara T, Akiyama K, Kishida T, Yamauchi S, Bioorganic & Medicinal Chemistry Letters, 24, 17, 4231, 4235, 20140900, 0960-894X, 10.1016/j.bmcl.2014.07.033
  • Nobiletin, a polymethoxy flavonoid, exerts anti-allergic effect by suppressing activation of phosphoinositide 3-kinase., S. Onishi, K. Nishi, S. Yasunaga, A. Muranaka, K. Maeyama, A. Kadota and T. Sugahara, J. Funct. Foods, 6, 1, 606, 614, 20140700, 10.1016/j.jff.2013.12.005
  • Activation of macrophages stimulated by the bengkoang fiber extract through toll-like receptor 4., Kumalasari ID, Nishi K, Putra AB, Sugahara T, Food & Function, 5, 7, 1403, 1408, 20140700, 2042-6496, 10.1039/c3fo60360a
  • Cytotoxic activity of dietary lignan and its derivatives: structure-cytotoxic activity relationship of dihydroguaiaretic acid., Wukirsari T, Nishiwaki H, Nishi K, Sugahara T, Akiyama K, Kishida T, Yamauchi S, Journal of Agricultural and Food Chemistry, 62, 23, 5305, 5315, 20140600, 0021-8561, 10.1021/jf5010572
  • Tributyltin induces cell cycle arrest at G1 phase in the yeast Saccharomyces cerevisiae., Sekito T, Sugimoto N, Ishimoto M, Kawano-Kawada M, Akiyama K, Nishimoto S, Sugahara T, Kakinuma Y, The Journal of Toxicological Sciences, 39, 2, 311, 317, 20140400, 0388-1350, 10.2131/jts.39.311
  • Jellyfish collagen stimulates production of TNF-α and IL-6 by J774.1 cells through activation of NF-κB and JNK via TLR4 signaling pathway., Putra AB, Nishi K, Shiraishi R, Doi M, Sugahara T, Molecular Immunology, 58, 1, 32, 37, 20140300, 0161-5890, 10.1016/j.molimm.2013.11.003
  • Immunomodulatory activity of Bengkoang (Pachyrhizus erosus) fiber extract in vitro and in vivo., Kumalasari ID, Nishi K, Harmayani E, Raharjo S, Sugahara T, Cytotechnology, 66, 1, 75, 85, 20140100, 0920-9069, 10.1007/s10616-013-9539-5
  • Antiproliferative activity and its underlying mechanisms of methanol extract from leaves of Saururus chinensis (Lour.) Baill. on mouse Colon-26 carcinoma cells., M. Daifuku, K. Nishi, H. Nishiwaki, I.-H. Kim, S. Kim and T. Sugahara, J. Appl. Res. Nat. Prod., 7, 17, 27, 20140000
  • Cellular mechanism of the cytotoxic effect of extracts from Syzygium polyanthum leaves., Sulistiyani, S. Falah, W.T. Wahyuni, T. Sugahara, S. Tachibana and Syaefudin, Am. J. Drug Discov. Dev., 4, 2, 90, 101, 20140000, 10.3923/ajdd.2014.90.101
  • Structure-cytotoxic activity relationship of sesquilignan, morinol A., Yamauchi S, Kawahara S, Wukirsari T, Nishiwaki H, Nishi K, Sugahara T, Akiyama K, Kishida T, Bioorganic & Medicinal Chemistry Letters, 23, 17, 4923, 4930, 20130900, 0960-894X, 10.1016/j.bmcl.2013.06.067
  • Quantitative structure-activity relationship analysis of antifungal (+)-dihydroguaiaretic acid using 7-phenyl derivatives., Hasebe A, Nishiwaki H, Akiyama K, Sugahara T, Kishida T, Yamauchi S, Journal of Agricultural and Food Chemistry, 61, 36, 8548, 8555, 20130900, 0021-8561, 10.1021/jf4015526
  • Effect of bengkoang (Pachyrhizus erosus) fiber extract on murine macrophage-like J774.1 cells and mouse peritoneal macrophages., I.D. Kumalasari, K. Nishi, E. Harmayani, S. Raharjo and T. Sugahara, J. Funct. Foods, 5, 2, 582, 589, 20130400, 10.1016/j.jff.2012.12.005
  • Inhibitory effect of chlorophyll c2 from brown algae, Sargassum horneri, on degranulation of RBL-2H3 cells., H. Yoshioka, A. Kamata, T. Konishi, J. Takahashi, H. Oda, T. Tamai, H. Toyohara and T. Sugahara, J. Funct. Foods, 5, 1, 204, 210, 20130100, 10.1016/j.jff.2012.10.006
  • Inhibitory effect of aqueous spinach extract on degranulation of RBL-2H3 cells., Ishida M, Nishi K, Watanabe H, Sugahara T, Food Chemistry, 136, 2, 322, 327, 20130100, 0308-8146, 10.1016/j.foodchem.2012.08.079
  • Phenylhydroquinone induces loss of thymocytes through cell cycle arrest and apoptosis elevation in p53-dependent pathway., Nakata Y, Nishi K, Nishimoto S, Sugahara T, The Journal of Toxicological Sciences, 38, 3, 325, 335, 20130000, 0388-1350, 10.2131/jts.38.325
  • Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs., Kurogi K, Alazizi A, Liu MY, Sakakibara Y, Suiko M, Sugahara T, Liu MC, Biochemical Pharmacology, 84, 9, 1186, 1195, 20121100, 0006-2952, 10.1016/j.bcp.2012.08.009
  • Effect of substituents at phenyl group of 7,7'-dioxo-9,9'-epoxylignane on antifungal activity., Nishiwaki H, Ouchi M, Matsugi J, Akiyama K, Sugahara T, Kishida T, Yamauchi S, Bioorganic & Medicinal Chemistry Letters, 22, 21, 6740, 6744, 20121100, 0960-894X, 10.1016/j.bmcl.2012.08.078
  • Immunomodulatory effects of citrus fruit auraptene in vitro and in vivo., S. Nishimoto, A. Muranaka, K. Nishi, A. Kadota and T. Sugahara, J. Funct. Foods, 4, 4, 883, 890, 20121000, 10.1016/j.jff.2012.06.005
  • Immunomodulatory effects of lactate dehydrogenase in vitro and in vivo., M. Daifuku, K. Nishi, T. Okamoto, S. Nishimoto and T. Sugahara, J. Funct. Foods, 4, 4, 972, 978, 20121000, 10.1016/j.jff.2012.07.005
  • Immunochromatographic assay of cadmium levels in oysters., Nishi K, Kim IH, Itai T, Sugahara T, Takeyama H, Ohkawa H, Talanta, 97, 262, 266, 20120800, 0039-9140, 10.1016/j.talanta.2012.04.028
  • Immunostimulatory effect of b-cryptoxanthin in vitro and in vivo., K. Nishi, A. Muranaka, S. Nishimoto, A. Kadota and T. Sugahara, J. Funct. Foods, 4, 3, 618, 625, 20120700, 10.1016/j.jff.2012.04.001
  • Effect of collagens from jellyfish and bovine Achilles tendon on the activity of J774.1 and mouse peritoneal macrophage cells., A.B.N. Putra, H. Morishige, S. Nishimoto, K. Nishi, R. Shiraishi, M. Doi and T. Sugahara, J. Funct. Foods, 4, 2, 504, 512, 20120400, 10.1016/j.jff.2012.02.011
  • Nobiletin suppresses adipocyte differentiation of 3T3-L1 cells by an insulin and IBMX mixture induction., Kanda K, Nishi K, Kadota A, Nishimoto S, Liu MC, Sugahara T, Biochimica et Biophysica Acta, 1820, 4, 461, 468, 20120400, 0006-3002, 10.1016/j.bbagen.2011.11.015
  • Evaluation of immunostimulatory effect of the arrowroot (Maranta arundinacea. L) in vitro and in vivo., Kumalasari ID, Harmayani E, Lestari LA, Raharjo S, Asmara W, Nishi K, Sugahara T, Cytotechnology, 64, 2, 131, 137, 20120300, 0920-9069, 10.1007/s10616-011-9403-4
  • Immunostimulatory effects of water extract from bulbus arteriosus in tuna in vitro., M. Daifuku, K. Nishi, T. Okamoto, H. Nakano, S. Nishimoto and T. Sugahara, J. Funct. Foods, 4, 1, 263, 270, 20120100, 10.1016/j.jff.2011.12.002
  • (-)-Secoisolariciresinol attenuates high-fat diet-induced obesity in C57BL/6 mice., Tominaga S, Nishi K, Nishimoto S, Akiyama K, Yamauchi S, Sugahara T, Food & Function, 3, 1, 76, 82, 20120100, 2042-6496, 10.1039/c1fo10166h
  • Immunostimulatory effects of collagen from jellyfish in vivo., Morishige H, Sugahara T, Nishimoto S, Muranaka A, Ohno F, Shiraishi R, Doi M, Cytotechnology, 63, 5, 481, 492, 20111000, 0920-9069, 10.1007/s10616-011-9371-8
  • Heavy oil fraction induces the dysplastic sperm in male mouse., S. Nishimoto, K. Akiyama, Y. Kakinuma, S. Kitamura and T. Sugahara, J. Toxicol. Sci., 36, 4, 487, 491, 20110800, 10.2131/jts.36.487
  • Immunomodulatory effect of (-)-matairesinol in vivo and ex vivo., M. Yamawaki, K. Nishi, S. Nishimoto, S. Yamauchi, K. Akiyama, T. Kishida, M. Maruyama, H. Nishiwaki and T. Sugahara, Biosci. Biotechnol. Biochem., 75, 5, 859, 863, 20110000, 0916-8451|1347-6947, 10.1271/bbb.100781
  • Disruption of ion homeostasis by verrucosin and its related compound., K. Akiyama, J. Tone, S. Yamauchi, T. Sugahara, M. Maruyama and Y. Kakinuma, Biosci. Biotechnol. Biochem., 75, 5, 1000, 1002, 20110000, 0916-8451|1347-6947, 10.1271/bbb.110004
  • Inhibition of myotube formation by paraquat in the myoblast cell line C2C12., K. Akiyama, J. Tone, M. Okabe, S. Nishimoto, T. Sugahara and Y. Kakinuma, J. Toxicol. Sci., 36, 2, 243, 246, 20110400, 0388-1350|1880-3989, 10.2131/jts.36.243
  • Immunostimulation effects of yellowtail heart extracts in vitro and in vivo., M. Daifuku, Y. Yaguchi, K. Nishi, T. Okamoto, H. Nakano, S. Nishimoto, S. Nishikawa, H. Yamashita, S. Takimoto and T. Sugahara, Biosci. Biotechnol. Biochem., 75, 4, 638, 645, 20110000, 0916-8451|1347-6947, 10.1271/bbb.100713
  • Bfr1p is responsible for tributyltin resistance in Schizosaccharomyces pombe., K. Akiyama, T. Iwaki, N. Sugimoto, S. Chardwiriyapreecha, M. Kawano, S. Nishimoto, T. Sugahara, T. Sekito and Y. Kakinuma, J. Toxicol. Sci., 36, 1, 117, 120, 20110200, 0388-1350|1880-3989, 10.2131/jts.36.117
  • Immunostimulatory in vitro and in vivo effects of a water-soluble extract from kale., K. Nishi, A. Kondo, T. Okamoto, H. Nakano, M. Daifuku, S. Nishimoto, K. Ochi, T. Takaoka and T. Sugahara, Biosci. Biotechnol. Biochem., 75, 1, 40, 46, 20110000, 0916-8451|1347-6947, 10.1271/bbb.100490
  • Antifungal activity of morinol B derivatives of tetrahydropyran sesquilignan., K. Masuda, H. Nishiwaki, K. Akiyama, S. Yamauchi, M. Maruyama, T. Sugahara and T. Kishida, Biosci. Biotechnol. Biochem., 74, 10, 2071, 2076, 20100000, 0916-8451|1347-6947, 10.1271/bbb.100422
  • Zebrafish as a model for the study of the phase II cytosolic sulfotransferases., T.-A. Liu, S. Bhuiyan, M.-Y. Liu, T. Sugahara, Y. Sakakibara, M. Suiko, S. Yasuda, Y. Kakuta, M. Kimura, F.E. Williams and M.-C. Liu, Curr. Drug Metab., 11, 6, 538, 546, 20100000, 10.2174/138920010791636158
  • IgE suppressive activity of (-)-matairesinol and structure-activity relationship., S. Kawahara, I. Iwata, E. Fujita, M. Yamawaki, H. Nishiwaki, T. Sugahara, S. Yamauchi, K. Akiyama and T. Kishida, Biosci. Biotechnol. Biochem., 74, 9, 1878, 1883, 20100000, 0916-8451|1347-6947, 10.1271/bbb.100275
  • Improved syntheses of morinol C and D by employing Mizoroki-Heck 4 reaction and their cytotoxic and antimicrobial activities., K. Ogura, T. Sugahara, M. Maruyama, K. Akiyama and S. Yamauchi, Biosci. Biotechnol. Biochem., 74, 8, 1641, 1644, 20100000, 0916-8451|1347-6947, 10.1271/bbb.100255
  • Proteose peptone fraction of bovine milk depressed IgE production in vitro and in vivo., F. Ohno, T. Sugahara, K. Kanda and S. Nishimoto, Biosci. Biotechnol. Biochem., 74, 7, 1332, 1337, 20100000, 0916-8451|1347-6947, 10.1271/bbb.90809
  • In vitro and in vivo anti-tumor effects of novel Span 80 vesicles containing immobilized Eucheuma serra agglutinin., Y. Omokawa, T. Miyazaki, P. Walde, K. Akiyama, T. Sugahara, S. Masuda, A. Inada, Y. Ohnishi, T. Saeki and K. Kato, Int. J. Pharm., 389, 1-2, 157, 167, 20100000, 0378-5173, 10.1016/j.ijpharm.2010.01.033
  • Oral administration of paraquat perturbs immunoglobulin productivity in mouse., M. Okabe, S. Nishimoto, T. Sugahara, K. Akiyama and Y. Kakinuma, J. Toxicol. Sci., 35, 2, 257, 263, 20100400, 0388-1350|1880-3989, 10.2131/jts.35.257
  • The differentiation of myoblast cells to myotube by paraquat., M. Okabe, K. Akiyama, S. Nishimoto, T. Sugahara and Y. Kakinuma, Animal Cell Technology: Basic & Applied Aspects, 16, 215, 219, 20100000
  • The Effect of secoisolariciresinol on 3T3-L1 adipocytes and the relationship between molecular structure and the activity., S. Tominaga, T. Sugahara, S. Nishimoto, M. Yamawaki, Y. Nakashima, T. Kishida, K. Akiyama, M. Maruyama and S. Yamauchi, Animal Cell Technology: Basic & Applied Aspects, 16, 345, 351, 20100000
  • The effects of pesticides on immune cells., S. Nishimoto, K. Kanda, M. Okabe, K. Akiyama, Y. Kakinuma and T. Sugahara, Animal Cell Technology: Basic & Applied Aspects, 16, 377, 382, 20100000
  • Heavy oil fractions induce negative influences on mouse immune system., S. Nishimoto, K. Kanda, M. Yamawaki, M. Okabe, K. Akiyama, Y. Kakinuma and T. Sugahara, J. Toxicol. Sci., 34, 5, 459, 468, 20091000, 0388-1350, 10.2131/jts.34.459
  • Tributyltin induces Yca1p-dependent cell death of yeast Saccharomyces cerevisiae., T. Chahomchuen, K. Akiyama, T. Sekito, N. Sugimoto, M. Okabe, S. Nishimoto, T. Sugahara and Y. Kakinuma, J. Toxicol. Sci., 34, 5, 541, 545, 20091000, 0388-1350, 10.2131/jts.34.541
  • Severe abnormalities in the reproductive organs of mice caused by chemical substances contained in heavy oil., S. Nishimoto, M. Yamawaki, K. Akiyama, S. Kitamura and T. Sugahara, J. Toxicol. Sci., 34, 2, 239, 244, 20090400, 0388-1350, 10.2131/jts.34.239
  • Paraquat modulates the differentiation of C2C12 cells to myotube., M. Okabe, K. Akiyama, S. Nishimoto, T. Sugahara and Y. Kakinuma, Interdisciplinary Studies on Environmental Chemistry: Environmental Research in Asia for Establishing a Scientist's Network, 2, 219, 226, 20090000
  • Abnormal response induced by pesticides on mammalian immune system., S. Nishimoto, K. Kanda, M. Okabe, K. Akiyama, Y. Kakinuma and T. Sugahara, Interdisciplinary Studies on Environmental Chemistry: Environmental Research in Asia for Establishing a Scientist's Network, 2, 211, 218, 20090000
  • White sorghum (Sorghum bicolor (L.) Moench) bran extracts suppressed IgE production by U266 cells., T. Sugahara, S. Nishimoto, Y. Morioka, K. Nakano and K. Nakano, Biosci. Biotechnol. Biochem., 73, 9, 2043, 2047, 20090000, 0916-8451|1347-6947, 10.1271/bbb.90245
  • Inhibition of discoloration of yellowtail dark muscle by lignan., S. Yamauchi, T. Kishida, T. Sugahara, M. Yamawaki, S. Nishimoto, Y. Shinomiya and T. Yamamoto, Biosci. Biotechnol. Biochem., 73, 8, 1718, 1721, 20090000, 0916-8451|1347-6947, 10.1271/bbb.80830
  • Antimicrobial activity of stereoisomers of butane type of lignans., Y. Kawaguchi, S. Yamauchi, K. Masuda, H. Nishiwaki, K. Akiyama, M. Maruyama, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 73, 8, 1806, 1810, 20090000, 0916-8451|1347-6947, 10.1271/bbb.90167
  • Syntheses and antimicrobial activity of tetrasubstituted tetrahydrofuran lignan stereoisomers., T. Nakato, S. Yamauchi, R. Tago, K. Akiyama, M. Maruyama, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 73, 7, 1608, 1617, 20090000, 0916-8451|1347-6947, 10.1271/bbb.90107
  • The Effect of secoisolariciresinol on 3T3-L1 adipocytes and the relationship between molecular structure and the activity., S. Tominaga, T. Sugahara, S. Nishimoto, M. Yamawaki, Y. Nakashima, T. Kishida, K. Akiyama, M. Maruyama and S. Yamauchi, Biosci. Biotechnol. Biochem., 73, 1, 35, 39, 20090000, 0916-8451|1347-6947, 10.1271/bbb.80393
  • Antimicrobial activity of stereoisomers of morinol A and B, tetrahydropyran sesquineolignan., K. Akiyama, S. Yamauchi, M. Maruyama, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 73, 1, 129, 133, 20090000, 0916-8451|1347-6947, 10.1271/bbb.80536
  • Characterization of amino acid recycling process in yeast autophagy., T. Chahomchuen, T. Sekito, K. Hondo, S. Nishimoto, T. Sugahara and Y. Kakinuma, Interdisciplinary Studies on Environmental Chemistry: Biological Responses to Chemical Pollutants, 1, 251, 261, 20080000
  • Vacuolar-type H+-translocating ATPase is the target of tributylin Chloride., K. Akiyama, S. Chardwiriyapreecha, T. Chahomchuen, N. Sugimoto, T. Sekito, S. Nishimoto, T. Sugahara and Y. Kakinuma, Interdisciplinary Studies on Environmental Chemistry: Biological Responses to Chemical Pollutants, 1, 241, 249, 20080000
  • Risk assessment of heavy oil on terrestrial mammals., S. Nishimoto, M. Yamawaki, S.-I. Kitamura, K. Akiyama, Y. Kakinuma and T. Sugahara, Interdisciplinary Studies on Environmental Chemistry: Biological Responses to Chemical Pollutants, 1, 269, 274, 20080000
  • The structure-activity relationship of flaxseed lignan, secoisolariciresinol., T. Sugahara, S. Yamauchi, S. Nishimoto, A. Kondo, F. Ohno, S. Tominaga, Y. Nakashima, T. Kishida, K. Akiyama, M. Maruyama and Y. Kakinuma, Interdisciplinary Studies on Environmental Chemistry: Biological Responses to Chemical Pollutants, 1, 263, 268, 20080000
  • Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid., S. Yamauchi, T. Masuda, T. Sugahara, Y. Kawaguchi, M. Ohuchi, T. Someya, J. Akiyama, S. Tominaga, M. Yamawaki, T. Kishida, K. Akiyama and M. Maruyama, Biosci. Biotechnol. Biochem., 72, 11, 2981, 2986, 20080000, 0916-8451|1347-6947, 10.1271/bbb.80461
  • The mode of action of the immunostimulatory effect of collagen from jellyfish., S. Nishimoto, Y. Goto, H. Morishige, R. Shiraishi, M. Doi, K. Akiyama, S. Yamauchi and T. Sugahara, Biosci. Biotechnol. Biochem., 72, 11, 2806, 2814, 20080000, 0916-8451|1347-6947, 10.1271/bbb.80154
  • Syntheses of all stereoisomers of goniodiol from yeast-reduction products and their antimicrobiological activity., T. Yoshida, S. Yamauchi, R. Tago, M. Maruyama, K. Akiyama, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 72, 9, 2342, 2352, 20080000, 0916-8451|1347-6947, 10.1271/bbb.80262
  • Structure-antibacterial activity relationship of 9-O,9'-O-demethyl (+)-virgatusin., R. Tago, M. Maruyama, K. Akiyama, T. Sugahara, T. Kishida, Y. Koba and S. Yamauchi, Biosci. Biotechnol. Biochem., 72, 4, 1032, 1037, 20080000, 0916-8451|1347-6947, 10.1271/bbb.70783
  • Effects of polyamines on proliferation and IgM productivity of human-human hybridoma, HB4C5 cells., T. Sugahara, S. Nishimoto and Y. Miyazaki, Cytotechnology, 57, 2, 115, 122, 20080000, 0920-9069, 10.1007/s10616-007-9115-y
  • Stereoselective construction of tetra-substituted tetrahydrofuran compounds from benzylic hemiacetal in the presence of H2 and Pd catalyst: stereoselective synthesis of stereoisomer of (-)-virgatusin and antimicrobiological activity., T. Nakato, S. Yamauchi, R. Tago, K. Akiyama, M. Maruyama, T. Sugahara and T. Kishida, Biosci. Biotechnol. Biochem., 72, 1, 197, 203, 20080000, 0916-8451|1347-6947, 10.1271/bbb.70554
  • Immunostimulation effect of the jellyfish collagen., T. Sugahara, M. Ueno, Y. Goto, K. Akiyama, S. Yamauchi, R Shiraishi and M. Doi, Animal Cell Technology: Basic & Applied Aspects, 15, 307, 313, 20080000
  • First stereoselective synthesis of meso-secoisolariciresinol and comparison of biological activity with (+) and (-)-secoisolariciresinol., T. Sugahara, S. Yamauchi, A. Kondo, F. Ohno, S. Tominaga, Y. Nakashima, T. Kishida, K. Akiyama and M. Maruyama, Biosci. Biotechnol. Biochem., 71, 12, 2962, 2968, 20070000, 0916-8451|1347-6947, 10.1271/bbb.70358
  • Use of benzyl mesylate for the synthesis of tetrahydrofuran lignan: syntheses of 7,8-trans, 7',8'-trans, 7,7'-cis, 8,8'-cis-virgatusin stereoisomers., S. Yamauchi, T. Nakato, M. Tsuchiya, K. Akiyama, M. Maruyama, T. Sugahara and T. Kishida, Biosci. Biotechnol. Biochem., 71, 9, 2248, 2255, 20070000, 0916-8451|1347-6947, 10.1271/bbb.70236
  • Effect of benzylic structure of lignan on antioxidant activity., S. Yamauchi, T. Sugahara, J. Matsugi, T. Someya, T. Masuda, T. Kishida, K. Akiyama and M. Maruyama, Biosci. Biotechnol. Biochem., 71, 9, 2283, 2290, 20070000, 0916-8451|1347-6947, 10.1271/bbb.70275
  • Determination of the stereochemistry of the tetrahydropyran sesquineolignans morinols A and B., S. Yamauchi, T. Sugahara, K. Akiyama, M. Maruyama and T. Kishida, J. Nat. Prod., 70, 4, 549, 556, 20070000, 0163-3864, 10.1021/np060461j
  • Antimicrobiological activity of lignan: effect of benzylic oxygen and stereochemistry of 2,3-dibenzyl-4-butanolide and 3,4-dibenzyltetrahydrofuran lignans on activity., K. Akiyama, M. Maruyama, S. Yamauchi, Y. Nakashima, T. Nakato, R. Tago, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 71, 7, 1745, 1751, 20070000, 0916-8451|1347-6947, 10.1271/bbb.70168
  • Antifungal activity of tetra-substituted tetrahydrofuran lignan, (-)-virgatusin, and its structure-activity relationship., K. Akiyama, S Yamauchi, T. Nakato, M. Maruyama, T. Sugahara and T. Kishida, Biosci. Biotechnol. Biochem., 71, 4, 1028, 1035, 20070000, 0916-8451|1347-6947, 10.1271/bbb.60696
  • Antibacterial activity of virgatusin-related compound., M. Maruyama, S. Yamauchi, K. Akiyama, T. Sugahara, T. Kishida and Y. Koba, Biosci. Biotechnol. Biochem., 71, 3, 677, 680, 20070000, 0916-8451|1347-6947, 10.1271/bbb.60429
  • The anti-tumor effect of Euchema serra agglutinin on colon cancer cells in vitro and in vivo., Y. Fukuda, T. Sugahara, M. Ueno, Y. Fukuta, Y. Ochi, K. Akiyama, T. Miyazaki, S. Masuda, A. Kawakubo and K. Kato, Anti-cancer Drugs, 17, 8, 943, 947, 20060900, 0959-4973, 10.1097/01.cad.0000224458.13651.b4
  • Effect of benzylic oxygen on the cytotoxic activity for Colon 26 cell line of phenolic lignans., S. Yamauchi, T. Sugahara, Y. Nakashima, K. Abe, Y. Hayashi, K. Akiyama, T. Kishida and M. Maruyama, Biosci. Biotechnol. Biochem., 70, 12, 2942, 2947, 20060000, 0916-8451|1347-6947, 10.1271/bbb.60353
  • Radical and superoxide scavenging activity of matairesinol and oxidized matairesinol., S. Yamauchi, T. Sugahara, Y. Nakashima, A. Okada, K. Akiyama, T. Kishida, M. Maruyama and T. Masuda, Biosci. Biotechnol. Biochem., 70, 8, 1934, 1940, 20060000, 0916-8451|1347-6947, 10.1271/bbb.60096
  • Immunostimulation effect of the jellyfish collagen., T. Sugahara, M. Ueno, Y. Goto, R Shiraishi, M. Doi, K. Akiyama and S. Yamauchi, Biosci. Biotechnol. Biochem., 70, 9, 2131, 2137, 20060000, 0916-8451|1347-6947, 10.1271/bbb.60076
  • Molecular composition of non-ionic vesicles prepared from Span 80 or Span 85 by a two-step emulsification method., K. Kato, P. Walde, K. Akiyama and T. Sugahara, J. Disper. Sci. Technol., 27, 1217, 1222, 20060000, 10.1080/01932690600859903
  • Immunostimulation effect of the fermented milk on human hybridomas and peripheral blood lymphocytes., T. Sugahara, K. Nakamoto and K. Hara, Animal Cell Technology: Basic & Applied Aspects, 14, 185, 191, 20060000
  • Preparation of cationic immunovesicles containing cationic peptide lipid for specific drug delivery to target cells., T. Sugahara, S. Kawashima, A. Oda, Y. Hisaeda and K. Kato, Cytotechnology, 47, 1/3, 51, 57, 20050000, 0920-9069, 10.1007/s10616-005-3764-5
  • Gene transfection into HeLa cells by vesicles containing cationic peptide lipid., Y. Ohama, Y. Heike, T. Sugahara, K. Sakata, N. Yoshimura, Y. Hisaeda, M. Hosokawa, S. Takashima and K. Kato, Biosci. Biotechnol. Biochem., 69, 8, 1453, 1458, 20050000, 0916-8451|1347-6947, 10.1271/bbb.69.1453
  • Immunostimulation effects of proteose-peptone component 3 fragment on human hybridomas and peripheral blood lymphocytes., T. Sugahara, H. Onda, Y. Shinohara, M. Horii, K. Akiyama, K. Nakamoto and K. Hara, Biochim. Biophys. Acta, 1725, 233, 240, 20050000, 10.1016/j.bbagen.2005.05.008
  • First enantioselective synthesis of (-)- and (+)-virgatusin,tetra-substituted tetrahydrofuran lignan., S. Yamauchi, M. Okazaki, K. Akiyama, T. Sugahara, T. Kishida and T. Kashiwagi, Org. Biomol. Chem., 3, 9, 1670, 1675, 20050000, 1477-0520, 10.1039/b501151e
  • Identification of a novel zebrafish SULT1 cytosolic sulfotransferase: cloning, expression, characterization, and developmental expression study., M.-Y. Liu, Y.-S. Yang, T. Sugahara, S. Yasuda and M.-C. Liu, Arch. Biochem. Biophys., 437, 1, 10, 19, 20050000, 0003-9861, 10.1016/j.abb.2005.02.029
  • Specific targeting at ERM5-1 cell as a model human-brain tumor cell and the anti-tumor effect by using immunovesicles., K. Kato, T. Manabe, T. Sugahara, K. Akiyama, Y. Omokawa, N. Kamata and H. Yamazaki, Congress Proceedings of 10th The Asian Pacific Confederation of Chemical Engineering Congress, 1P-01-032, 1, 9, 20040000
  • Anti-cancer effect to colon cancer in either vitro or vivo using lipid vesicle combined with alga lectin ESA., K. Kato, Y. Omokawa, K. Akiyama, T. Sugahara, A. Kawakubo and T. Saeki, Congress Proceedings of 10th The Asian Pacific Confederation of Chemical Engineering Congress, 1P-01-033, 1, 10, 20040000
  • Lactate dehydrogenase enhances immunoglobulin production by human hybridoma and human peripheral blood lymphocytes., S. Takenouchi and T. Sugahara, Cytotechnology, 42, 3, 133, 143, 20030000, 0920-9069, 10.1023/B:CYTO.0000015838.06536.de
  • Sulphonation of dehydroepiandrosterone and neurosteroids: molecular cloning, expression, and functional characterization of a novel zebrafish SULT2 cytosolic sulphotransferase., T. Sugahara, Y.S. Yang, C.-C. Liu, T.G. Pai and M.-C. Liu, Biochem. J., 375, 3, 785, 791, 20030000, 0264-6021, 10.1042/BJ20031050
  • Sulfonation of environmental estrogens by zebrafish cytosolic sulfotransferases., K. Ohkimoto, T. Sugahara, Y. Sakakibara, M. Suiko, M.-Y. Liu, G. Carter and M.-C. Liu, Biochem. Biophys. Res. Commun., 309, 1, 7, 11, 20030000, 0006-291X, 10.1016/S0006-291X(03)01524-9
  • Sulfation of hydroxychlorobiphenyls: molecular cloning, expression, and functional characterization of zebrafish SULT1 sulfotransferases., T. Sugahara, C.-C. Liu, T.G. Pai, P. Collodi, M. Suiko, Y. Sakakibara, K. Nishiyama and M.-C. Liu, Eur. J. Biochem., 270, 11, 2404, 2411, 20030000, 0014-2956, 10.1046/j.1432-1033.2003.03608.x
  • cDNA cloning, expression, and functional characterization of a zebrafish SULT1 cytosolic sulfotransferase., T. Sugahara, C.-C. Liu, G. Carter, T.G. Pai and M.-C. Liu, Arch. Biochem. Biophys., 414, 1, 67, 73, 20030000, 0003-9861, 10.1016/S0003-9861(03)00172-3
  • High IgM production by human-human hybridoma HB4C5 cells cultured in microtubes., T. Sugahara, S. Yano and T. Sasaki, Biosci. Biotechnol. Biochem., 67, 2, 393, 395, 20030000, 0916-8451|1347-6947, 10.1271/bbb.67.393
  • Differential roles of human monoamine (M)-form and simple phenol (P)-form phenol sulfotransferases in drug metabolism., T. Sugahara, T.G. Pai, M. Suiko, Y. Sakakibara and M.-C. Liu, J. Biochem.-Tokyo, 133, 2, 259, 262, 20030000, 0021-924X|1756-2651, 10.1093/jb/mvg033
  • Molecular cloning, expression, and functional characterization of a novel zebrafish cytosolic sulfotransferase., T. Sugahara, C.-C. Liu, T.G. Pai and M.-C. Liu, Biochem. Biophys. Res. Commun., 300, 3, 725, 730, 20030000, 0006-291X, 10.1016/S0006-291X(02)02915-7
  • Structure-function relationships in the stereospecific and manganese-dependent 3,4-dihydroxyphenylalanine/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase, SULT1A3., T.G. Pai, I. Oxendine, T. Sugahara, M. Suiko, Y. Sakakibara and M.-C. Liu, J. Biol. Chem., 278, 3, 1525, 1532, 20030000, 0021-9258, 10.1074/jbc.M203108200
  • Manganese stimulation and stereospecificity of the Dopa (3,4-dihydroxyphenylalanine)/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase. Kinetic studies of the mechanism using wild-type and mutant enzymes., T.G. Pai, K. Ohkimoto, Y. Sakakibara, M. Suiko, T. Sugahara and M.-C. Liu, J. Biol. Chem., 277, 46, 43813, 43820, 20020000, 0021-9258, 10.1074/jbc.M200785200
  • Increase of immunoglobulin productivity of human-human hybridoma HB4C5 cells by histone., T. Okamoto, T. Sugahara, H. Tachibana and K. Yamada, Biosci. Biotechnol. Biochem., 66, 6, 1241, 1245, 20020000, 0916-8451|1347-6947, 10.1271/bbb.66.1241
  • Differential xenoestrogen-sulfating activities of the human cytosolic sulfotransferases: molecular cloning, expression, and purification of human SULT2B1a and SULT2B1b sulfotransferases., T.G. Pai, T. Sugahara, M. Suiko, Y. Sakakibara, F. Xu and M.-C. Liu, Biochim. Biophys. Acta, 1573, 165, 170, 20020000, 10.1016/S0304-4165(02)00416-6
  • Heat denaturation enhanced immunoglobulin production stimulating activity of lysozyme from hen egg white., T. Sugahara, Y. Yamada, S. Yano and T. Sasaki, Biochim. Biophys. Acta, 1572, 19, 24, 20020000, 10.1016/S0304-4165(02)00272-6
  • The cytotoxic effect of Eucheuma serra agglutinin (ESA) on cancer cells and its application to molecular probe for drug delivery system using lipid vesicles., T. Sugahara, Y. Ohama, A. Fukuda, M. Hayashi, A. Kawakubo and K. Kato, Cytotechnology, 36, 1/3, 93, 99, 20010000, 0920-9069, 10.1023/A:1014057407251
  • Immunoglobulin production stimulating activity of heat-denatured lysozyme., T. Sugahara, Y. Yamada, Y. Ueda, S. Matsubara and T. Sasaki, Animal Cell Technology: Basic & Applied Aspects, 12, 179, 183, 20010000
  • Alcohol dehydrogenase-I from horse liver serves as an immunoglobulin production stimulating factor., OKAMOTO T, FURUTANI H, SASAKI T, SUGAHARA T, Enzyme Microb. Technol., 29, 2/3, 136, 143, 20010000, 0141-0229, 10.1016/S0141-0229(01)00371-4
  • Application of the lipid vesicle immobilized Eucheuma serra lectin for target-specific drug delivery., T. Sugahara, K. Kato, A. Fukuda, A. Yoshihiro, N. Yohimura, N. Tateishi, and A. Kawakubo, Proc. of Biotechnology 2000 (The World Congress on Biotechnology), 83, 85, 20000000
  • Preparation of an immunovesicle for specific combining to target cells toward either DDS or gene transfection., K. Kato, T. Sugahara, S. Kawashima, Y. Hayashi, A. Oda, Y. Hisaeda, T. Hayashi and T. Sasaki, Proc. of Biotechnology 2000 (The World Congress on Biotechnology), 79, 81, 20000000
  • The mode of actions of lysozyme as an immunoglobulin production stimulating factor., T. Sugahara, F. Murakami, Y. Yamada and T. Sasaki, Biochim. Biophys. Acta, 1475, 27, 34, 20000000, 10.1016/S0304-4165(00)00041-6
  • Study of the specific binding between lipid vesicles and human-human hybridoma toward either DDS or gene transfection., K. Kato, T. Sugahara, S. Kawashima, Y. Hayashi, A. Yoshihiro and T. Sasaki, Animal Cell Technology: Products from Cells, Cells as Products, 433, 435, 19990000
  • Study of DDS for cancer therapy applying lipid vesicle immobilizing Eucheuma Serra lectin., K. Kato, T. Sugahara, Y. Maruyama, N. Yoshimura, A. Yoshihiro, N. Tateishi, Y. Suzuki, A. Kawakubo and T. Sasaki, Animal Cell Technology: Products from Cells, Cells as Products, 429, 431, 19990000
  • Effects of DNA on immunoglobulin production stimulating activity of alcohol dehydrogenase., T. Okamoto, H. Furutani, T. Sasaki and T. Sugahara, Cytotechnology, 31, 1/2, 95, 102, 19990000, 0920-9069, 10.1023/A:1008024322602
  • The mode of actions of lysozyme as an immunoglobulin production stimulating factor (IPSF)., T. Sugahara, F. Murakami and T. Sasaki, Animal Cell Technology: Products from Cells, Cells as Products, 43, 45, 19990000
  • Aldolase from rabbit muscle enhances immunoglobulin production by human hybridoma and human peripheral blood lymphocytes., T. Sugahara, F. Moriya, H. Myoga, T. Uchiyama and T. Sasaki, Enzyme Microb. Technol., 24, 1/2, 41, 47, 19990000, 0141-0229, 10.1016/S0141-0229(98)00087-8
  • Inhibition of immunoglobulin production stimulating activity of glyceraldehyde-3-phosphate dehydrogenase by nucleotides., T. Sugahara and T. Sasaki, Biosci. Biotechnol. Biochem., 62, 6, 1237, 1239, 19980000, 0916-8451|1347-6947, 10.1271/bbb.62.1237
  • A novel function of enolase from rabbit muscle; an immunoglobulin production stimulating factor., T. Sugahara, S. Shimizu, M. Abiru, S. Matsuoka and T. Sasaki, Biochim. Biophys. Acta, 1380, 163, 176, 19980000, 10.1016/S0304-4165(97)00137-2
  • Spermine enhances IgM productivity of human-human hybridoma HB4C5 cells and human peripheral blood lymphocytes., Y. Miyazaki, S. Nishimoto, T. Sasaki and T. Sugahara, Cytotechnology, 26, 2, 111, 118, 19980000, 0920-9069, 10.1023/A:1007939213564
  • Enhancement of immunoglobulin production of hybridomas and lymphocytes by alcohol dehydrogenase-I., T. Sugahara, H. Furutani, F. Murakami, S. Shimizu, F. Moriya, Y. Miyazaki, S. Nishimoto and T. Sasaki, Biochemical Engineering: Marching Toward The Century of Biotechnology, 157, 160, 19970000
  • Alcohol dehydrogenase-I from horse liver stimulates immunoglobulin production by human hybridoma and human peripheral blood lymphocytes., T. Sugahara, H. Furutani and T. Sasaki, Mol. Cell. Biochem., 173, 113, 119, 19970000
  • Immunoglobulin production stimulating activities of basic proteins., T. Sugahara, M. Fujisawa, S. Matsuoka, F. Murakami, H. Furutani, M. Abiru, T. Uchiyama and T. Sasaki, Animal Cell Technology: Basic & Applied Aspects, 8, 209, 215, 19970000
  • Lysozyme stimulates immunoglobulin production by human-human hybridoma and human peripheral blood lymphocytes., F. Murakami, T. Sasaki and T. Sugahara, Cytotechnology, 24, 117, 182, 19970000, 10.1023/A:1007936629501
  • Enhancement of IgM production of human peripheral blood lymphocytes by rice fermented seasoning under serum-free cultivation., T. Sugahara, K. Fukaya and T. Sasaki, J. Ferment. Bioeng., 82, 1, 77, 79, 19960000, 0922-338X, 10.1016/0922-338X(96)89459-1
  • Effects of sodium poly(styrene sulfonate) on antibody production and cell growth HB4C5 hybridoma cells., K. Nagira, M. Hayashida, M. Shiga, K. Sasamoto, K. Kina, K. Osada, T. Sugahara, T. Hara, Y. Yamamoto and H. Murakami, Polym. J., 27, 7, 719, 727, 19950000, 0032-3896|1349-0540, 10.1295/polymj.27.719
  • Immunoglobulin production stimulating activities of nucleic acid-binding proteins., T. Sugahara, S. Shirahata, T. Sasaki and H. Murakami, Animal Cell Technology: Developments towards the 21st Century, 501, 507, 19950000
  • Effects of organic pH buffers on cell growth and antibody production of human-human hybridoma HB4C5 cells in a serum-free culture., K. Nagira, M. Hayashida, K. Sasamoto, K. Kina, K. Osada, T. Sugahara and H. Murakami, Cytotechnology, 17, 2, 117, 125, 19950000, 0920-9069, 10.1007/BF00749399
  • The mode of actions of glyceraldehyde-3-phosphate dehydrogenase identified as an immunoglobulin production stimulating factor, T. Sugahara, S. Shirahata, T. Sasaki and H. Murakami, FEBS Letters, 368, 1, 92, 96, 19950000, 0014-5793, 10.1016/0014-5793(95)00607-B
  • Removability and permeability of DNA in protein solution using BMM., T. Hirasaki, K. Yamaguchi, A. Kono, T. Noda, T. Sugahara, N. Yamamoto and H. Murakami, Animal Cell Technology: Basic & Applied Aspects, 6, 543, 547, 19940000
  • Synthesis of bis-piperazine-type pH buffer agents and their application to mammalian cell cultures., K. Nagira, M. Shiga, K. Sasamoto, K. Kina, M. Hayashida, T. Sugahara and H. Murakami, Biosci. Biotechnol. Biochem., 58, 8, 1370, 1375, 19940000, 0916-8451|1347-6947, 10.1271/bbb.58.1370
  • Enhancement of immunoglobulin productivity of human-human hybridoma HB4C5 cells by basic proteins and poly-basic amino acids., T. Sugahara, T. Sasaki and H. Murakami, Biosci. Biotechnol. Biochem., 58, 12, 2212, 2214, 19940000, 10.1271/bbb.58.2212
  • Immunoglobulin production stimulating factors., H. Murakami, T. Sugahara and H. Nakajima, Cell Biology and Biotechnology: Novel Approaches to Increased Cellular Productivity, 35, 62, 19930000
  • Immunoglobulin production stimulating factor (IPSF) derived from Namalwa cells., T. Sugahara, H. Nakajima, S. Shirahata, K. Nagamine and Murakami, Animal Cell Technology: Basic & Applied Aspects, 5, 601, 607, 19930000
  • Serum-free culture of human-human hybridoma secreting monoclonal antibody against stomach cancer., A.M. Ali, M. Hayashida, T. Sugahara, K. Akiyama, M.M. Dahan and H. Murakami, Animal Cell Technology: Basic & Applied Aspects, 4, 321, 326, 19920000
  • Virus containment continuous culture of animal cells., T. Sugahara, T. Noda, T. Tsuboi, T. Hirasaki, N. Yamamoto, S. Sakaeda and H. Murakami, Animal Cell Technology: Basic & Applied Aspects, 4, 233, 237, 19920000
  • Purification and characterization of immunoglobulin production stimulating factor-IIβ derived from Namalwa cells., T. Sugahara, H. Nakajima, S. Shirahata and H. Murakami, Cytotechnology, 10, 2, 137, 146, 19920000, 0920-9069, 10.1007/BF00570890
  • Purification and characterization of immunoglobulin production stimulating factor IIα derived from Namalwa cells., H. Murakami, T. Sugahara, S. Shirahata and K. Yamada, Production of Biologicals from Animal Cells in Culture, 735, 741, 19910000
  • Immunoglobulin production stimulating factor-IIα (IPSF-IIα) is glyceraldehyde-3-phosphate dehydrogenase like protein., T. Sugahara, S. Shirahata, K. Akiyoshi, T. Isobe, T. Okuyama and H. Murakami, Cytotechnology, 6, 2, 115, 120, 19910000, 0920-9069, 10.1007/BF00373028
  • Large-scale, high-density freezing of hybridomas and its application to high-density culture., N. Ninomiya, T. Sugahara, S. Shirahata and H. Murakami, Biotechnol. Bioeng., 38, 9, 1110, 1113, 19910000, 0006-3592, 10.1002/bit.260380920
  • Purification of immunoglobulin production stimulating factor IIα derived from Namalwa cells., T. Sugahara, S. Shirahata, K. Yamada and H. Murakami, Cytotechnology, 5, 3, 255, 263, 19910000, 0920-9069, 10.1007/BF00556295
  • Enhancement of immunoglobulin production of human-human hybridomas by immunoglobulin production stimulating factors., Trends in Animal Cell Culture Technology, 291, 297, 19900000
  • Relationship between oxygen consumption rate and cellular activity of mammalian cells culturedin serum-free media., K. Yamada, S. Furushou, T. Sugahara, S. Shirahata and H. Murakami, Biotechnol. Bioeng., 36, 7, 759, 762, 19900000, 0006-3592, 10.1002/bit.260360715
  • Purification and characterization of immunoglobulin production stimulating factor derived from human B lymphoblastoid HO-323 cells., K. Toyoda, T. Sugahara, K. Inouye, K. Yamada, S. Shirahata and H. Murakami, Cytotechnology, 3, 189, 197, 19900000
  • Stimulation of proliferation and immunoglobulin M production by lactoferrin in human-human and mouse-mouse hybridomas cultures in serum-free conditions., K. Yamada, I. Ikeda, T. Sugahara, S. Hashizume, S. Shirahata and H. Murakami, Cytotechnology, 3, 123, 131, 19900000
  • Screening of immunoglobulin production stimulating factor (IPSF) in foodstuffs using human-human hybridoma HB4C5 cells., K. Yamada, I. Ikeda, T. Sugahara, S. Shirahata and H. Murakami, Agric. Biol. Chem., 53, 11, 2987, 2991, 19890000, 0002-1369|1881-1280, 10.1271/bbb1961.53.2987
  • Stimulation of monoclonal antibody production by human-human hybridoma cells with an elevated concentration of potassium or sodium phosphate in serum-free medium., S. Sato, H. Murakami, T. Sugahara, T. Ikegami, K. Yamada, H. Omura and S. Hashizume, Cytotechnology, 2, 63, 67, 19890000
  • Partial purification and characterization of immunoglobulin production stimulating factor derived from Namalwa cells., K. Yamada, K. Akiyoshi, H. Murakami, T. Sugahara, I. Ikeda, K. Toyoda and H. Omura, In Vitro Cell. Develop. Biol., 25, 243, 247, 19890000

書籍等出版物

講演・口頭発表等

  • Anti-allergy effect of nobiletin from citrus peel and development of functional food, T. Sugahara, K. Nishi, M. Ishida, 9th International Conference on Nutrition and Physical Activity (NAPA 2018), 20181217, 招待有り
  • 柑橘成分の抗アレルギー効果とそれを活用した機能性食品開発, 菅原 卓也, 第38回日本看護科学学会学術集会, 20181215, 招待有り
  • Anti-metabolic syndrome activity of flaxseed lignan., Sugahara T., ASEAN - Japan Network for Transdisciplinary Research and Practice for Reducing Environmental Problems (TRPNEP2018), 20181209, 招待有り
  • Development of functional foods., Sugahara T., ASEAN - Japan Network for Transdisciplinary Research and Practice for Reducing Environmental Problems (TRPNEP2018), 20181208, 招待有り
  • 柑橘成分の機能性評価と機能性食品開発, 菅原卓也, 平成30年度「知」の集積による産学連携支援事業 新品種「阿波すず香」をはじめとする徳島県産香酸柑橘類の機能を活かした事業化・商品化の可能性調査第1回検討会, 20181204, 招待有り
  • クミン種子抽出物の脱顆粒抑制効果に関する研究, 秦 麻琴・石田萌子・西 甲介・恩田浩幸・西本壮吾・菅原卓也, 20181109
  • Anti-allergic effect of citrus component and development of functional foods, Sugahara T., Functional food: Potency, reseach and commercialutilization, 20181102, 招待有り
  • ノビレチンの脂肪細胞に対する抗炎症効果, 菅原卓也・道免未来・石田萌子・西 甲介, ノビレチン研究会, 20181019
  • Anti-allergic effect of water-soluble extract of cumin seeds., Hada M, Ishida M., Onda H., Nishimoto S., Nishi K., Sugahara T., The 11th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2018), 20181015
  • Effect of lysozyme on lipopolysaccharide-induced inflammation model mice., Tagashira A., Nishi K., Matsumoto S., Sugahara T., The 11th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2018), 20181015
  • Evaluation of food functions., Sugahara T., Udayana University, Guest lecture, 20180928, 招待有り
  • Health function of citrus and development of functional foods., Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 20180926, 招待有り
  • Immature black vinegar extract activates macrophages., Ishii E., Nishi K., Ishida M., Nagano M., Hashiguchi K., Fujii A. Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 20180926
  • Anti-inflammatory effect of placenta water-soluble extract on macrophages., Yokotani M., Nishi K., Sasaki Y. and Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 20180926
  • Anti-allergic effect of clove., Murielle D.T.A., Ishida M. Onda H., Nishi K. and Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 20180926
  • Anti-inflammatory effect of aqueous extract from Kawachi-bankan peel on lipopolysaccharide-induced inflammatory responses in RAW264.7 cells., Ishida M., Takekuni C., Nishi K., Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 20180926
  • Anti-inflammatory effect of lysozyme from hen egg white., Tagashira A., Nishi K., Matsumoto S. and Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 20180926
  • Inhibitory effect of caffeine on degranulation of RBL-2H3 cells., Nugrahini A.D., Ishida M., Nishi K. and Sugahara T., The 5th International Conference on Agro-Industry (ICoA2018), 20180926
  • Functional foods in Japan., Sugahara T., Gadjah Mada University Guest lecture, 20180829, 招待有り
  • Health functions of Indonesian local crops., Sugahara T., Airlangga University Seminar, 20180814, 招待有り
  • The suppressive effect of tropical fruits on IgE production., Sugahara T., Recent trends and future prespectives on functional food ingredients, 20180811, 招待有り
  • Anti-metabolic syndrome activity of foods., Sugahara T., 1st International Nutrition Science Conference (INSC2018), 20180801, 招待有り
  • Health functions of Indonesian local crops., Sugahara T., Seminr National, 20180712, 招待有り
  • 乳酸菌TJ515菌の抗アレルギー効果に関する研究, 菅原卓也・井上愛理・西 甲介・石田萌子, 日本アレルギー学会, 20180622
  • The suppressive effect of ethanol extract from passion fruit seeds on IgE production, Sugahara T., Mizusaki A., Nishi K., HiSEA 2018, Opportunities in Developing & Implementing Sustainable Functional Foods and Nutraceuticals, 20180328, 招待有り
  • パッションフルーツ種子エタノール抽出物のIgE産生抑制効果, 菅原卓也・水崎 愛・石田萌子・西 甲介, 第6回あしなが予防医学研究会, 20180303
  • Evaluation of food functions and development of functional foods. - Anti-allergic effect of citrus -., Sugahara T., General lecture, Hasanuddin University., 20171130, 招待有り
  • ノビレチンの抗アレルギー効果と機能性食品開発, 菅原卓也, ノビレチン研究会 第1回学術研究会 シンポジウム, 20171125, 招待有り
  • 柑橘成分の機能性評価と機能性食品開発, 菅原卓也, 平成29年度近畿中国四国農業試験研究推進会議作物生産推進部会 食品流通問題別研究会, 20171116, 招待有り
  • Suppressive effect of ethanol extract from mango (Mangifera indica L.) peel on IgE production in vitro and in vivo., Ishida M., Sasaki T., Nishi K., Tamamoto T., Sugahara T., The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), 20171022
  • Anti-inflammatory effect of lysozyme from hen egg white on macrophages., Tagashira A., Nishi K., Mastumoto S., Sugahara T., The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), 20171022
  • Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells., Sugahara T., Domen M., Yasunaga S., Nishi K., Ishida M., Kadota A., The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), 20171022
  • Anti-allergic effect of Coriandrum sativum L. leaf extract., Kitamura Y., Ishida M., Onda H., Nishimoto S., Nishi K., Sugahara T., The 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), 20171022
  • 柑橘成分の健康機能とそれを活用した商品開発, 菅原卓也, 平成29年度コミュニティーカレッジ11 愛媛の研究機関講座, 20171017, 招待有り
  • Development of functional foods based on health function research on foods. - Anti-allergic effect of citrus -., Sugahara T., Guest lecture, Widya Mandala Catholic University, 20170915, 招待有り
  • 柑橘果皮成分の抗アレルギー効果と機能性食品開発について, 菅原卓也, 日本農芸化学会 サイエンスカフェ2017 in 松山 みかんを食べて健康になろう ー柑橘成分の健康効果ー, 20170913
  • クミン種子水溶性抽出物がマクロファージ活性化に与える影響, 中山大輔・石田萌子・西 甲介・恩田浩幸・西本壮吾・菅原卓也, 第32回日本香辛料研究会, 20170901
  • パクチー抽出物の脱顆粒抑制メカニズムの解明, 北村優莉佳・石田萌子・西 甲介・恩田浩幸・西本壮吾・菅原卓也, 第32回日本香辛料研究会, 20170901
  • Evaluation of food functions and development of functional foods.,, Sugahara T., Guest lecture, Ahmad Dahlan University, 20170831, 招待有り
  • Evaluation of food functions and development of functional foods., Sugahara T., Focus Group Discussion on International Collaborative Research, Jember University, 20170810, 招待有り
  • Health Functions of Indonesian Local Crops., Sugahara T., Focus Group Discussion on International Collaborative Research, Jember University, 20170810, 招待有り
  • 食物アレルギーモデルマウスに対する黒酢の摂取効果, 石田萌子・粟根聖次・西 甲介・長野正信・橋口和典・藤井 暁・菅原卓也, 日本動物細胞工学会2017年度大会(JAACT2017), 20170720
  • パクチー水溶性抽出物の抗アレルギー効果に関する研究, 北村優莉佳・石田萌子・西 甲介・恩田浩幸・西本壮吾・菅原卓也, 日本動物細胞工学会2017年度大会(JAACT2017), 20170720
  • 卵白由来リゾチームのマクロファージに対する抗炎症効果, 田頭歩佳・西 甲介・松本真弥・菅原卓也, 日本動物細胞工学会2017年度大会(JAACT2017), 20170720
  • プラセンタ水溶性抽出物の抗炎症効果, 横谷みゆき・西 甲介・佐々木義晴・菅原卓也, 日本動物細胞工学会2017年度大会(JAACT2017), 20170720
  • 柑橘果皮配合ヨーグルトの抗アレルギー効果, 菅原卓也・安永 翔・原 裕子・白石 敦・坂根由梨・鎌尾知行・竹澤由起・大橋裕一・菊池泰三・窪 千明・門田 歩・西 甲介, 日本動物細胞工学会2017年度大会(JAACT2017), 20170720
  • クミン種子水溶性抽出物の脱顆粒抑制メカニズムの解明, 秦 麻琴・石田萌子・西 甲介・恩田浩幸・西本壮吾・菅原卓也, 日本動物細胞工学会2017年度大会(JAACT2017), 20170720
  • クミン種子のマクロファージ活性化作用とその活性因子の同定, 中山大輔・石田萌子・西 甲介・恩田浩幸・西本壮吾・菅原卓也, 日本動物細胞工学会2017年度大会(JAACT2017), 20170720
  • 黒酢のアレルギー症状緩和効果に関する研究, 菅原 卓也, 第4回日本黒酢研究会, 20170623, 招待有り
  • コリアンダー(Coriandrum sativum L.)種子水溶性抽出物の免疫賦活活性に関する研究, 石田萌子・國廣菜波・西 甲介・恩田浩幸・西本壮吾・菅原卓也, 第71回日本栄養・食糧学会大会, 20170519
  • クミン種子水溶性抽出物の免疫賦活効果に関する研究, 中山大輔・石田萌子・西 甲介・恩田浩幸・西本壮吾・菅原卓也, 第71回日本栄養・食糧学会大会, 20170519
  • Functional foods with the anti-allergy activity., Health Ingredients South East Asia -International Conference on Revitalising & Repositioning Functional Foods and Neutraceuticals as Essential Indicator of Wellness., 20170323, 招待有り
  • パッションフルーツ種子エタノール抽出物のIgE産生抑制効果に関する研究, 水崎 愛・西 甲介・玉元武司・菅原卓也, 日本農芸化学会2017年度大会, 20170318
  • ナツメグエタノール抽出物が示す貪食活性のメカニズム解析, 平野里枝・佐々木藍美・恩田浩幸・菅原卓也・西本壮吾, 日本農芸化学会2017年度大会, 20170318
  • ブタン型リグナン、ノルリグナン、ネオリグナンの生物活性の比較, 西本明日香・西脇 寿・西 甲介・菅原卓也・秋山浩一・山内 聡, 日本農芸化学会2017年度大会, 20170318
  • ミカンを食べて健康維持 ~柑橘成分の保健機能性について~, 菅原 卓也, 神戸薬科大学 第17回健康食品講座, 20170219, 招待有り
  • 柑橘成分の抗アレルギー効果と機能性食品開発, 菅原卓也, 第5回あしなが予防医学研究会, 20170218
  • 水産物の機能性評価, 菅原卓也, 平成28年度水産イノベーションスキル修得講座, 20170121
  • Immunostimulatory effect of jellyfish collagen., Sugahara T., Workshop on Food Function, 20161219
  • ポリメトキシフラボノイドの抗アレルギー効果, 菅原卓也, 第14回機能性食品医用学会総会, 20161210, 招待有り
  • Academic writing and publishing for international journals., Sugahara T., University of Pembangunan Nasional “Veteran” Jawa Timur, 20161202, 招待有り
  • The suppressive effect of ethanol extract from passion fruit seeds on IgE production., The 29th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2016), 20161109
  • Anti-allergic effect of Awabancha-tea., The 29th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2016), 20161109
  • Functional Foods with the antiallergy activity., The 29th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2016), 20161109, 招待有り
  • Effect of major spice extracts on response of mammalian immune cells., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 20161024
  • Immunostimulatory effect of dried coriander seed extract on mouse macrophage-like RAW264.7 cells and mouse peritoneal macrophages., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 20161024
  • Effects of 3-phenylamino-L-alanine (PAA) and 4-aminophenol (4-AP) on chemotaxis and expression of chemokine receptors in human eosinophils., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 20161024
  • Immunostimulatory effect of dried bonito extract on mouse macrophage-like J774.1 cells and mouse peritoneal macrophages., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 20161024
  • Effect of lysozyme on RAW264.7 cells stimulated by lipopolysaccharide., Sugahara T., Matsumoto S. and Nishi K., The 17th International Biotechnology Symposium and Exhibition (IBS2016), 20161024
  • ミカンの皮の驚くべき健康効果 ~花粉症対策機能性食品の開発~, 菅原卓也, 日本家政学会中国・四国支部/日本調理科学会中国・四国支部合同公開講演会, 20161001, 招待有り
  • The development of functional foods: from bench to mass production., Sugahara T., Indonesia International Institute for Life Science , 20160927, 招待有り
  • カカオ抽出物の免疫機能に及ぼす効果, 菅原卓也, 第21回チョコレート・ココア国際栄養シンポジウム, 20160916, 招待有り
  • 黒酢のスギ花粉症症状緩和効果に関する研究, 粟根聖次・石田萌子・西 甲介・長野正信・橋口和典・藤井 暁・菅原卓也, 日本農芸化学会2016年度中四国支部大会, 20160915
  • 温州ミカン果皮水溶性抽出物の抗アレルギー効果に関する研究, 中田晶大・西 甲介・門田 歩・菅原卓也, 日本農芸化学会2016年度中四国支部大会, 20160915
  • パッションフルーツ種子エタノール抽出物のIgE産生抑制効果に関する研究, 水崎 愛・西 甲介・玉元武司・菅原卓也, 日本農芸化学会2016年度中四国支部大会, 20160915
  • コリアンダー(Coriandrum sativum L.)種子水溶性抽出物の免疫賦活活性に関する研究, 石田萌子・國廣菜波・西 甲介・恩田浩幸・西本壮吾・菅原卓也, 日本農芸化学会2016年度中四国支部大会, 20160915
  • パクチーエタノール抽出物のHeLa細胞に対する細胞増殖抑制効果に関する研究, 細谷美沙・恩田浩幸・西 甲介・西本壮吾・菅原卓也, 日本農芸化学会中四国支部例会第45回講演会, 20160915
  • 産学官による機能性食品開発, 菅原卓也, 日本学術会議若手アカデミー公開シンポジウム 世代の知をつなぐ地域創生とイノベーション, 20160822, 招待有り
  • 柑橘成分の抗アレルギー効果とそれを活用した商品開発, 菅原卓也, 2016年度第39回日本ライセンス協会年次大会 招待講演, 20160701, 招待有り
  • 柑橘成分の抗アレルギー効果と商品開発, 菅原卓也, 第12回医食農連携プラットフォーム研究会, 20160515
  • Nプラスヨーグルト! 花粉症緩和に効果あり!?, 菅原卓也, JA厚生連健康まつり2016 らくれん健康セミナー, 20160508, 招待有り
  • 香辛料による免疫賦活効果の検討, 西本壮吾・佐々木藍美・平野里枝・恩田浩幸・菅原卓也, 日本農芸化学会2016年度大会, 20160327
  • 温州ミカン果皮及び摘果ポンカン配合ヨーグルト中のノビレチンの分析, 福田直大・玉井敬久・永田洋子・菅 忠明・門家重治・菅原卓也・菊池泰三・門田 歩, 日本農芸化学会2016年度大会, 20160327
  • マタイレジノール誘導体緒細胞毒性, 越智吉明・トゥッティ ウキルサリ・西脇 寿・西 甲介・菅原卓也・山内 聡, 日本農芸化学会2016年度大会, 20160327
  • 河内晩柑果皮水溶性抽出物の抗炎症作用に関する研究, 竹國千尋・西 甲介・福田直大・玉井敬久・菅原卓也, 日本農芸化学会2016年度大会, 20160327
  • Anti-allergic function of microbial-fermented tea, Ishiduchi black tea, Sugahara T., Kondo M. and Nishi K., 国際シンポジウム 発酵茶に関する複合領域的研究, 20160325, 招待有り
  • 水産物のブランド戦略, 菅原卓也, 平成27年度水産イノベーションスキル修得講座, 20160206
  • Anti-allergic function of microbial-fermented tea in Ehime, Japan., Sugahara T., i3L Half-day Food Science Seminar, 20151222, 招待有り
  • 黒酢の抗アレルギー効果, 菅原卓也、粟根聖次、石田萌子、西 甲介、長野正信、橋口和典、藤井 暁, 第4回あしなが予防医学研究会 , 20151128
  • Anti-allergic effect of a microbial-fermented tea, Ishizuchi dark tea., Sugahara T., Kondo M., Ishida M. and Nishi K., The 6th International Conference on Food Factors (ICoFF 2015), 20151122
  • 柑橘成分の機能性とそれを活用した商品開発, 菅原卓也, 食と健康を学ぶ会 第12回講演会, 20151115, 招待有り
  • 河内晩柑果皮水溶性抽出物の過剰炎症モデルマウスに対する効果, 菅原卓也, 第3回 河内晩柑「食と健康セミナー」, 20151109
  • Immunological functions of bengkoang fiber extracts., Sugahara T., The second International Conference on Agro-industry (ICoA 2015), 20151107, 招待有り
  • Health functions of Indonesian local crops: insight from biomolecular perspective., Sugahara T., i3L Power Talk, 20151019, 招待有り
  • Immunostimulatory effect of jellyfish collagen., Sugahara T., Putra A.B.N., Nishi K. and Doi M., Bali International Seminar on Science and Technology (BISSTECH 3 2015) (October 15-16, Bali, Indonesia), 20151015, 招待有り
  • Effect of bengkoang (Pachyrhizus erosus) fiber extract on murine macrophage-like J774.1 cells and mouse peritoneal macrophages., Sugahara T., Kumalasari I.D., Nishi K. and Putra A.B.N., 7th International Conference and Exhibition on Nutraceuticals and Functional Foods (ISNFF 2014), 20151014
  • Anti-allergic function of microbial-fermented tea produced in Ehime, Japan., Sugahara T., Kondo M., Putra A.B.N. and Nishi K., Bali International Seminar on Science and Technology II 2014 (BISSTECH 2014), 20150902, 招待有り
  • Studies on the stimulatory effects of jellyfish collagen on innate immune system., Sugahara T., The 3rd Third International Conference on Sustainable Agriculture and Natural Recourses Management, 20150806, 招待有り
  • Health function of lignan from flaxseeds., Sugahara T., 12th Asian Congress of Nutrition (ACN2015), 20150515, 招待有り
  • 柑橘成分の保健機能性解明研究, 菅原卓也, 福井県立大学生物資源学特別セミナー, 20150207, 招待有り
  • 河内晩柑果皮の抗炎症効果について, 菅原卓也, 食品健康科学研究センター第3回食と健康市民セミナー, 20141212
  • かんきつ類など地元食材を活用した機能性食品の開発促進に向けて, 菅原卓也, 四国経済連合会四国西南開発特別委員会 講演会, 20141125, 招待有り
  • Immunological functions of Indonesian local crops., Sugahara T., Synergy of Food, Feed, and Renewable Energy 2014 (SPRINT 2014), 20141021, 招待有り
  • Immunological functions of Indonesian local crops., Sugahara T., University of Pembangunan Nasional Veteran East Java, 20140908, 招待有り
  • アマニリグナンであるSecoisolariciresinolの脂肪蓄積抑制効果に関する研究, 菅原卓也, 第11回日本機能性食品医用学会総会, 20131207
  • 河内晩柑果皮の免疫促進効果と抗アレルギー効果について, 菅原卓也, 食品健康科学研究センター第1回食と健康市民セミナー, 20131101
  • 二段発酵茶の抗アレルギー効果に関する研究, 菅原卓也, 2013年度生物機能研究会, 20130720
  • Studies on immunotoxicity of o-phenylphenol (OPP) and metabolite., Sugahara T., Nakata Y., Nishi K. and Nishimoto S., The 25th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2012), 20121127
  • 食品開発における栄養と機能, 菅原卓也, 平成24年度えひめ新事業創出人材育成講座, 20121110, 招待有り
  • Effect of flaxseed lignan on lipid accumulation in adipocytes., Sugahara T., Tominaga S., Yamauchi S., Nishimoto S. and Nishi K., International Conference on Food Factors (ICoFF) 2011, 20111120
  • Effect of secoisolariciresinol on adipogenesis., Sugahara T., Tominaga S., Yamauchi S., Maruyama M., The 14th International Biotechnology Symposium and Exhibition (IBS2010), 20110914
  • Effects of endosulfan on allergic response., Sugahara T., Nishimoto S., Atobe S., Hosoba K., Okabe M. and Kakinuma Y., The 23rd Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2010), 20110901
  • Evaluation of food functions by animal cell culture and experimental animals., Sugahara T., Nishi K. and Nishimoto S., Gadjah Mada-Ehime Network (GEN) 2010, 20110807
  • Anti-cancer effect of lectin from red sea alga., Sugahara T., Tominaga S., Yamauchi S., Nishimoto S. and Nishi K., The 2nd International Symposium on Temulawak, 20110525, 招待有り
  • 9-norlignanの7位のphenyl基上の構造と細胞毒性活性との関係, 庄司有璃子・谷村僚亮・西脇 寿・西 甲介・菅原卓也・山内 聡, 日本農芸化学会2016年度大会

作品

MISC

  • ミカン酢ヨーグルト, 菅原 卓也, マキノ出版ムック ミカン酢でやせる!美肌に変身!, 30, 322, 20190300
  • 花粉症に特効のミカンの皮ヨーグルトに酢が加わればさらに効果アップと期待!, 菅原 卓也, 安心, 37, 3, 33, 36, 20190300
  • 果物の健康効果は、果皮にあり!, 菅原 卓也, 果実日本, 74, 2, 1, 1, 20190200
  • 連載・愛媛大学における特色有る取り組み6:最先端研究の推進~リサーチユニットの形成, 菅原 卓也, 文部科学教育通信, 452, 1, 22, 23, 20190100
  • 青ポンカンノビレチンの抗アレルギー効果, 菅原 卓也, Food Style 21, 22, 7, 47, 49, 20180700
  • ミカンの皮とヨーグルトの組み合わせは花粉症の症状を一掃する, 菅原 卓也, 安心, 36, 2, 94, 98, 20180200
  • あなたの暮らす街の特産品が秘めたチカラをどれだけ知っていますか エントリーNo. 50 愛媛県 ハマチ, 菅原 卓也, 健康365, 14, 9, 161, 161, 20170900
  • あなたの暮らす街の特産品が秘めたチカラをどれだけ知っていますか エントリーNo. 49 愛媛県 温州ミカン, 菅原 卓也, 健康365, 14, 9, 160, 161, 20170900
  • ポリメトキシフラボノイドの抗アレルギー活性, 菅原 卓也, 機能性食品と薬理栄養, 10, 6, 354, 359, 20170600
  • ミカンの皮に豊富な特効成分で花粉症の目のかゆみを撃退 丸ごとミカンスムージー, 菅原 卓也, わかさ, 28, 9, 63, 64, 20170500
  • ミカンの皮+飲むヨーグルトの相乗効果, 菅原卓也, 現代農業, 96, 3, 190, 193, 20170300
  • 産学官連携における機能性食品開発, 菅原 卓也, 学術の動向, 22, 2, 56, 58, 20170200
  • ミカン果皮の機能性と商品開発, 菅原卓也, 食品と開発, 51, 10, 64, 66, 20161000
  • 愛媛大学における機能性食品開発, 菅原卓也, 栄養教諭, 45, 10, 42, 45, 20161000
  • 愛媛の柑橘果皮を活用した機能性食品開発, 菅原卓也, 地方創生に関わる生物工学の取り組み ー日本各地の活動とネットワークの必要性ー, 58, 60, 20161000
  • アマニ(亜麻仁)リグナンの保健機能の解明と機能性食品開発, 菅原卓也, JATAFFジャーナル, 3, 8, 35, 40, 20150800
  • 温州ミカン果皮を用いた花粉症対策商品開発, 菅原卓也、門田 歩, 月刊FOOD STYLE 21, 19, 8, 38, 41, 20150800
  • 柑橘果皮成分の抗アレルギー効果の解明, 安永 翔、門田 歩、菅原卓也, 生物機能研究, 19, 1, 1, 6, 20150000
  • ブリ心臓でヒトの免疫促進 ~加工残渣の有効活用~, 菅原卓也、岡本威明, 月刊養殖, 49, 3, 30, 33, 20130300
  • ホウレンソウ由来脱顆粒抑制物質に関する研究, 石田萌子、西 甲介、菅原卓也, 生物機能研究, 17, 1, 13, 19, 20130000
  • ラット好塩基球様細胞株RBL-2H3の脱顆粒に及ぼすカゼイン由来ペプチドおよび関連アミノ酸の影響, 田中 守, 山岸賢司, 菅原卓也, 廣内智子, 岡本威明, 日本食品科学工学会誌, 59, 11, 556, 561, 20121200, 10.3136/nskkk.59.556
  • 温州ミカン果皮成分の免疫促進活性, 菅原卓也、門田 歩, 月刊FOOD STYLE 21, 16, 2, 45, 47, 20120200
  • 水産物資源の有効活用に関する研究 ~ハマチ心臓、マグロ動脈球の免疫促進活性について~, 大福美帆、岡本威明、菅原卓也, 生物機能研究, 15, 1, 24, 30, 20110000
  • 動物細胞と実験動物を用いた生理活性物質の機能解明, 菅原卓也, 月刊愛媛ジャーナル, 22, 8, 60, 63, 20090800
  • 良くわかる界面化学 界面活性剤を利用したナノカプセルによる薬物運搬体および遺伝子導入体の開発, 菅原卓也、加藤敬一, 化学と教育, 55, 184, 187, 20070000, 10.20665/kakyoshi.55.4_184
  • 食品タンパク質およびペプチドの免疫調節機構, 岡本威明、菅原卓也、立花宏文、山田耕路, 生物機能研究会誌, 6, 25, 31, 20020000
  • 癌細胞への標的機能を有する脂質膜ベシクルの創製, 加藤敬一、菅原卓也、佐々木毅、丸山祐樹、吉村和憲、川久保明宏, 化学工学シンポジウムシリーズ76 高機能界面・分子集合体の基礎構築と応用分野の新展開, 230, 238, 20010000
  • ヒト型ハイブリドーマの抗体産生促進機構に関する研究, 菅原卓也, 日本農芸化学会誌, 74, 10, 1107, 1112, 20001000, 0002-1407|1883-6844, 10.1271/nogeikagaku1924.74.1107
  • ハイブリドーマによるモノクローナル抗体の効率的生産に関する研究, 菅原卓也, 日本農芸化学会誌, 74, 9, 986, 989, 20000000, 0002-1407|1883-6844, 10.1271/nogeikagaku1924.74.986
  • 癌治療DDSへの利用を目指した脂質ベシクルの創製, 加藤敬一、川嶋真一、菅原卓也, ケミカルエンジニアリング, 45, 457, 463, 20000000
  • モノクローナル抗体生産性の増強, 菅原卓也, 生物機能研究会誌, 2, 18, 23, 19980000
  • レーザー共焦点顕微鏡による蛍光観察, 菅原卓也, 生物機能研究会誌, 2, 60, 64, 19980000
  • コメ発酵エキス中の増殖促進因子、および抗体産生促進因子の検索, 菅原卓也, 日本農芸化学会誌, 70, 801, 802, 19960000

その他研究情報

特許

受賞

  • 20170700, 日本動物細胞工学会2017年度大会(JAACT2017), 日本動物細胞工学会2017年度大会優秀ポスター賞, パクチー水溶性抽出物の抗アレルギー効果に関する研究
  • 20161100, 国立研究開発法人農業・食品産業総合研究機構, 平成28年度全国食品技術研究会賞 優秀賞
  • 20161100, 愛媛新聞社, 愛媛農林水産賞 技術開発賞, エヌプラスドリンクヨーグルト
  • 20150300, 日本農芸化学会2015年度大会, 日本農芸化学会2015年度大会トピックス賞, 温州ミカン果皮配合ヨーグルトのアレルギー症状緩和効果の検討
  • 20111100, International Conference on Food Factors (ICoFF) 2011, Poster Award, Effect of flaxseed lignan on lipid accumulation in adipocytes.
  • 20000300, 日本農芸化学会, 日本農芸化学会 農芸化学奨励賞, ヒト型ハイブリドーマの抗体産生促進機構に関する研究
  • 20171000, 10th International Conference and Exhibition on Nutraceuticals & Functional Foods (ISNFF2017), ISNFF2017 Poster Award, Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells.


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