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岩田 久人イワタ ヒサト

所属部署
沿岸環境科学研究センター
職名教授
メールアドレスiwata.hisato.mz[at]ehime-u.ac.jp ※[at]を@に書き換えて送信して下さい
ホームページURLhttp://ecotoxiwata.jp/
生年月日
Last Updated :2017/09/02

研究者基本情報

所属学協会

  • 環境毒性学と環境化学の会(Society of Environmental Toxicology and Chemistry)
  • 日本環境化学会
  • 環境科学会
  • 日本獣医学会
  • 日本内分泌攪乱化学物質学会
  • 日本環境毒性学会
  • 日本BICER協議会
  • 日本生化学会
  • 日本分子生物学会
  • Society of Toxicology

研究活動情報

研究分野

  • 環境影響評価・環境政策
  • 放射線・化学物質影響科学
  • 応用ゲノム科学
  • 資源保全学
  • 環境農学

研究キーワード

    生態系影響評価, 環境分析, 環境汚染, リスク評価, 環境毒性学, 環境化学, 生物遺伝子資源保全, エコトキシコゲノミクス, 水圏環境保全学

MISC

  • 有機スズ化合物による海洋汚染と生物への蓄積
    NETWORK, 36,   1994年
  • バイカル湖における有機塩素化合物汚染
    日本BICER協議会1993年度年報,   1994年
  • 有機塩素化合物によるバイカル湖の汚染
    文部省国際学術研究(1992-1993)研究成果報告書,   1994年
  • 強毒性有機化合物の指標動物-環境汚染を検知するためのバイオマーカーの有効性について-
    獣医畜産新報, (8月号) 665 - 669,   1996年
  • 野生高等動物における有機スズ化合物の蓄積
    東京大学海洋研究所大槌臨海研究センター報告書第21号, (21) 61 - 62,   1996年
  • 知床半島に飛来したオオワシの有機塩素化合物汚染
    知床博物館研究報告,   1997年
  • 環境庁の「ダイオキシンのリスク評価」では野生動物を保護できない
    哺乳類科学, 38, (1) 93 - 95,   1998年
  • 残留性有機塩素化合物の水生生物への影響-特にダイオキシン類に着目して-
    水環境学会誌7月号, 21, (7) 13 - 17,   1998年
  • 内分泌撹乱化学物質による海棲哺乳類・鳥類への生体影響
    海洋と生物, 117, (20) 270 - 276,   1998年
  • 猛禽類オオワシ、オジロワシおよびイヌワシにおける微量元素の蓄積特性
    安永 玄太, 田辺 信介, 金 恩英, 岩田 久人, 須藤 明子, 増田 泰, 藤田 正一, 神 和夫, 環境科学会誌, 13, (1) 51 - 59,   2000年
  • 有機塩素化合物による鳥類の汚染および影響の実態解明
    科学技術庁復興調整費、生活・社会基盤研究のうちの生活者ニーズ対応研究、「内分泌撹乱物質による生殖への影響とその作用機構に関する研究」研究報告書,   2001年
  • 薬物代謝酵素誘導を用いたバイオアッセイの環境研究への適用
    革新的技術開発研究推進費補助金総合研究、「ダイオキシン類・PCBの分解処理とバイオアッセイモニタリング」平成12年度研究報告書,   2001年
  • 水圏生物への環境汚染物質の影響とその評価
    日本環境毒性学会主催、生態影響試験と評価に関するセミナー2001、「環境中化学物質の生態影響に関する最近の研究と動向」,   2001年
  • 薬物代謝酵素誘導系を用いたバイオアッセイによる環境生態研究
    革新的技術開発研究推進費補助金総合研究、「ダイオキシン類・PCBの分解処理とバイオアッセイモニタリング」(課題番号12321)平成13年度研究報告書,   2002年
  • 残留性有機汚染物質による水圏野生生物のチトクロムP450発現系への影響
    生活衛生,   2002年
  • 薬物代謝酵素の測定
    野生生物のダイオキシン類蓄積状況等調査マニュアル、(財)自然環境研究センター,   2002年
  • ブラジル沿岸に座礁した小型鯨類の有機塩素化合物汚染
    平成13年度内分泌攪乱物質問題に関する日英共同研究報告書、(株)みなまた環境テクノセンター,   2002年
  • 平成13年度内分泌攪乱化学物質問題に関する日英共同研究 派遣研究者報告書
    平成13年度内分泌攪乱物質問題に関する日英共同研究報告書、(株)みなまた環境テクノセンター,   2002年
  • クロアシアホウドリの微量元素蓄積に関与するメタロチオネインの役割とMT cDNAのクローニング
    Biomed. Res. Trace Elements,   2002年
  • D-2 有害化学物質による地球規模の海洋汚染評価手法の構築に関する研究,(3)有害化学物質の地球規模での時空間変動機構および分解過程に関する研究
    地球環境研究総合推進費平成13年度研究成果―中間成果報告集―,環境省地球環境局研究調査室,   2002年
  • 薬物代謝酵素誘導系を用いたバイオアッセイの環境生態研究
    産学官連携イノベーション創出事業費補助金、「ダイオキシン類・PCBの分解処理とバイオアッセイモニタリング」(課題番号12321)平成14年度研究成果報告書,   2003年
  • 第7章 薬物代謝酵素誘導系を用いたバイオアッセイの環境生態研究
    産学官連携イノベーション創出事業費補助金、「ダイオキシン類・PCBの分解処理とバイオアッセイモニタリング」(課題番号12321)平成14年度研究成果総合研究報告書,   2003年
  • Seasonal variation of persistent organochlorine insecticide residues in Vellar river waters in Tamil Nadu,South India.
    RAMESH A, TANABE S, IWATA H, TATSUKAWA R, SUBRAMANIAN A N, MOHAN D, VENUGOPALAN V K, Environ.Pollut., 67, (4) 289 - 304,   1990年
  • Fate of the insecticide HCH in the tropical coastal area of South India.
    TAKEOKA H, RAMESH A, IWATA H, TANABE S, SUBRAMANIAN A N, MOHAN D, MAGENDRAN A, TATSUKAWA R, Mar.Pollut.Bull., 22, (6) 290 - 297,   1991年
  • Fate of HCH (BHC) in tropical paddy field : Application test in South India.
    TANABE S, RAMESH A, SAKASHITA D, IWATA H, TATSUKAWA R, MOHAN D, SUBRAMANIAN A N, Intern.J.Environ.Anal.Chem., 45, (1) 45 - 53,   1991年
  • Current status of contamination by persistent organochlorines in the lower Chao Phraya River,Thailand.
    Wat.Sci.Tech., 25, (11) 17 - 24,   1992年
  • Role of oceans in the fate of persistent organochlorines.
    In Proceedings of the International Symposium on Global Change (IGBP),   1993年
  • Distribution of persistent organochlorines in the oceanic air and surface seawater and the role of ocean on their global transport and fate
    IWATA H, TANABE S, SAKAI N, TATSUKAWA R, Environ.Sci.Technol., 27, (6) 1080 - 1098,   1993年
  • A new view on the divergence of HCH isomer compositions in oceanic air.
    IWATA H, TANABE S, TATSUKAWA R, Mar.Pollut.Bull., 26, (6) 302 - 305,   1993年
  • Geographical distribution of persistent organochlorines in air, water and sediments from Asia and Oceania, and their implications for global redistribution from lower latitudes.
    IWATA H, TANABE S, SAKAI N, NISHIMURA A, TATSUKAWA R, Environ.Pollut., 85, (1) 15 - 33,   1994年
  • Detection of butyltin compound residues in the blubber of marine mammals.
    IWATA H, TANABE S, MIYAZAKI N, TATSUKAWA R, Mar.Pollut.Bull., 28, (10) 607 - 612,   1994年
  • Global contamination by persistent organochlorines and its ecotoxicological impacts on marine mammals.
    Sci.Total Environ., 154,   1994年
  • Persistent organochlorine residues in sediments from the Chukchi Sea, Bering Sea and Gulf of Alaska.
    IWATA H, TANABE S, ARAMOTO M, SAKAI N, TATSUKAWA R, Mar.Pollut.Bull., 28, (12) 746 - 753,   1994年
  • Global monitoring of toxic contaminants with use of fishing vessels.
    In Proceedings of International Workshop on Techniques of Persistent Organic Pollutant Measurements in Northern Environments,Waterloo,Ontario,Canada,   1994年
  • Persistent organochlorine residues in air, water, sediments, and soils from the Lake Baikal Region, Russia.
    IWATA H, TANABE S, UEDA K, TATSUKAWA R, Environ.Sci.Technol., 29, (3) 792 - 801,   1995年
  • Environmental contamination by persistent toxic chemicals in Lake Baikal.
    In Proceeding of 6th International Conference on the Conservation and Management of Lake-Kasumigaura'95,Vol.2,Ibaragi,Japan,,   1995年
  • Concentrations of heavy metals, organochlorines and organotins in horseshoe crab,Tachypleus tridentatus,from Japanese coastal waters.
    KANNAN K, YASUNAGA Y, IWATA H, ICHIHASHI H, TANABE S, TATSUKAWA R, Arch.Environ.Contam.Toxicol., 28, (1) 40 - 47,   1995年
  • Butyltins in muscle and liver of fish collected from certain Asian and Oceanian countries.
    KANNAN K, TANABE S, IWATA H, TATSUKAWA R, Environ.Pollut., 90, (3) 279 - 290,   1995年
  • High accumulation of toxic butyltins in marine mammals from Japanese coastal waters
    IWATA H, TANABE S, MIZUNO T, TATSUKAWA R, Environ.Sci.Technol., 29, (12) 2959 - 2962,   1995年
  • Enantiomeric ratios of α-hexachlorocyclohexane in blubber of small cetaceans.
    TANABE S, KUMARAN P, IWATA H, TATSUKAWA R, MIYAZAKI N, Mar.Pollut.Bull., 32, (1) 27 - 31,   1996年
  • Specific accumulation and distribution of butyltin compounds in various organs and tissues of steller sea lion (Eumetopias jubatus) ; Comparison with organochlorine accumulation pattern
    KIM G B, LEE J S, TANABE S, IWATA H, TATSUKAWA R, SHIMAZAKI K, Mar. Pollut. Bull., 32, (7) 558 - 563,   1996年
  • Distribution, biomagnification, and elimination of butyltin compound residues in common cormorant (Phalacrocorax carbo) from Lake Biwa, Japan.
    Arch.Environ. Contam. Toxicol., 31, (2) 210 - 217,   1996年
  • Bioaccumulation of butyltin compounds in marine mammals : Their tissue distribution and composition.
    IWATA H, TANABE S, MIZUNO T, TATSUKAWA R, Appl. Organomet. Chem., 11, (4) 257 - 264,   1997年
  • Accumulation of butyltins in the liver and kidney of seabirds.
    Mar. Environ. Res., 44, (2) 191 - 199,   1997年
  • Isozyme selective alterations of the expression of cytochrome P450 during regeneration of male rat liver following partial hepatectomy.
    ISHIZUKA M, YOSHINO S, YAMAMOTO Y, YAMAMOTO H, IMAOKA S, FUNAE Y, MASUDA M, IWATA H, FUJITA S, Xenobiotica, 27, (9) 923 - 931,   1997年
  • Organochlorine pesticides and polychlorinated biphenylcongeners in wild terrestrial mammals and birds from Chubu region,Japan : Interspecies comparison of the residue levels and compositions.
    HOSHI H, MINAMOTO N, IWATA H, SHIRAKI K, TATSUKAWA R, TANABE S, FUJITA S, HIRAI K, KINJO T, Chemosphere, 36, (15) 3211 - 3221,   1998年
  • Accumulation of halogenated aromatic hydrocarbons and activities of cytochrome P450 and glutathione S-transferase in crabs from Japanese rivers.
    ISHIZUKA M, SAKIYAMA T, IWATA H, FUKUSHIMA M, KAZUSAKA A, FUJITA S, Environ. Toxicol. Chem., 17, (8) 1490 - 1498,   1998年
  • Molecular basis of the Dark Agouti rat drug oxidation polymorphism : Involvement of CYP2D1 and CYP2D2.
    Pharmacogenetics, 8,   1998年
  • Butyltin contamination in marine mammals from North Pacific and Asian coastal waters
    TANABE S, PRUDENTE M, MIZUNO T, HASEGAWA J, IWATA H, MIYAZAKI N, Environ. Sci. Technol., 32, (2) 193 - 198,   1998年
  • Enantioselective accumulation of alpfa-hexachlorocyclohexane in northern fur seals and double-crested cormorants : Effects of biological and ecological factors in the higher trophic levels.
    IWATA H, TANABE S, IIDA T, BABA N, LUDWIG J P, TATSUKAWA R, Environ. Sci. Technol., 32, (15) 2244 - 2249,   1998年
  • Effects of the agrochemicals butachlor, pretilachlor and isoprothiolane on rat liver xenobiotic-metabolizing enzymes.
    ISHIZUKA M, IWATA H, KAZUSAKA A, HATAKEYAMA S, FUJITA S, Xenobiotica, 28, (11) 1029 - 1039,   1998年
  • Expression and characterization of dog CYP2D15 using baculovirus expression system.
    J.Biochem., 123,   1998年
  • Regio-and stereoselectivity in propranolol metabolism by dog liver microsomes and dog CYP2D15.
    J.Biochem.,, 123,   1998年
  • Polychlorinated biphenyls (PCBs) and organochlorines (OCs) in water of the Vistula River at the Kiezmark site, Poland.
    Organohalogen Compounds, 39,   1998年
  • Seasonal concetrations of PCBs and organochlorine pesticides (OCs) in the ambient air in the city of Gdansk, Poland.
    Organohalogen Compounds, 39,   1998年
  • Butyltin and organochlorine contamination in marine mammals from the North Pacific and Asian coastal waters.
    In Proceedings of the Fourth Intemational Scientific Symposium IOC/WESTPAC,Okinawa,Japan,   1998年
  • Preliminary survey of lead poisoning of steller's sea eagle (Haliaeetus pelagicus) and white tailed eagle (Haliaeetus albicilla) in Hokkaido,Japan.
    KIM E‐Y, GOTO R, IWATA H, MASUDA Y, TANABE S, FUJITA S, Environ.Toxicol.Chem.,, 18, (3) 448 - 451,   1999年
  • Organochiorine pesticides and polychlorinated biphenyls in the Vistula river water.
    Rocz.Panstw.Zakl.Hig.,, 50, (2) 123 - 30,   1999年
  • Orgabichlorine pesticides and polychlorinated biphenyls in ambient air in the city of Gdansk.
    Rocz.Panstw.Zakl.Hig.,, 50, (1) 39 - 47,   1999年
  • Characterization of hepatic cytochrome P450 isozyme composition in the transgenic rat expressing low level human growth hormone.
    TAKAHASHI J, FURUHATA Y, IKEDA A, TAKAHASHI M, IWATA H, KAZUSAKA A, FUJITA S, Xenobiotica, 29, (12) 1203 - 1212,   1999年
  • Effects of concurrent exposure to 3-methylcholanthrene and vitamin A on fetal development in rats
    Jpn J Vet Res., 47, (1-2) 13 - 23,   1999年
  • Contamination by chlorinated hydrocarbons and lead in Steller's sea eagle and white-tailed sea eagle from Hokkaido,Japan.
    In:Ueta,M. & McGrady,M.J.(eds).First Symposium on Steller's and White-tailed Sea Eagles in East Asia.Wild Bird Society of Japan,Tokyo.Japan.,   2000年
  • In situ RT-PCR detection of CYP1A in pharyngeal epithelium and chondroid cells from chemically untreated fish : involvement in vertebrate craniofacial skeletal development?
    IWATA H, STEGEMAN J J, Biochem.Biophys.Res.Commun., 271, (1) 130 - 137,   2000年
  • Identification of novel cytochrome P450 1A genes from five marine mammal species.
    TERAMITSU I, YAMAMOTO Y, CHIBA I, IWATA H, TANABE S, FUJISE Y, KAZUSAKA A, AKAHORI F, FUJITA S, Aquatic Toxicol., 51, (2) 145 - 153,   2000年
  • Negative correlation between plasma thyroid hormone levels and chlorinated hydrocarbon levels accumulated in seals from the coast of Hokkaido, Japan.
    CHIBA I, SAKAKIBARA A, GOTO Y, ISONO T, YAMAMOTO Y, IWATA H, TANABE S, SHIMAZAKI K, AKAHORI F, Environ. Toxicol. Chem., 20, (5) 1092 - 1097,   2001年
  • Inhibitory effects of endogenous dopaminergic neurotoxin, norsalsolinol on dopamine secretion in PC12 rat pheochromocytoma cells.
    Neurochem. Int., 38, (7) 567 - 572,   2001年
  • P450 in wild animals as biomarker of environmental impact
    Biomarkers,   2001年
  • Hepatic microsomal cytochrome P450s and chlorinated hydrocarbons in largha and ribbon seals from Hokkaido, Japan: Differential response of seal species to Ah receptor agonist exposure
    Environ. Toxicol. Chem.,   2002年
  • Accumulation of coplanar PCB congeners, and induction of cytochrome P450 in seabirds
    Proceedings of International Workshop on marine pollution by persistent organic pollutants (POPs),   2002年
  • Accumulation patterns of polychlorinated biphenyl congeners and organochlorine pesticides in Steller's Sea eagles and White-tailed sea eagles, threatened species, in Hokkaido, Japan
    Environ. Toxicol. Chem.,   2002年
  • Species-specific responses of constitutively active receptor (CAR)-CYP2B coupling: Lack of CYP2B inducer-responsive nuclear translocation of CAR in marine teleost, scup (Stenotomus chrysops)
    Comp. Biochem. Physiol. Part C,   2002年
  • cDNA cloning of an aryl hydrocarbon receptor from Baikal seals (Phoca sibirica)
    Mar. Environ. Res.,   2002年
  • Specific accumulation of persistent organochlorines in bluefin tuna collected from Japanese coastal waters
    Mar. Pollut. Bull.,   2002年
  • Organochlorine and butyltin residues in deep-sea organisms collected from the western North Pacific, off-Tohoku, Japan
    Mar. Pollut. Bull.,   2002年
  • Accumulation of persistent organochlorines in resident white-breasted waterhens (Amaurornis phoenicurus) from Cambodia
    MONIRITH I, KUNISUE T, IWATA H, TANABE S, TANA T S, Mar. Pollut. Bull., 46, (10) 1341 - 1348,   2003年
  • Gene expression profiling in common cormorant liver with an oligo array: assessing the potential toxic effects of environmental contaminants
    NAKAYAMA Kei, IWATA Hisato, KIM Eun‐Young, TASHIRO Kosuke, TANABE Shinsuke, Environmental Science and Technology, 40, (3) 1076 - 1083,   2006年
  • Influence of endocrine disruptors on reproduction of aquatic animals in Indochina
    Proceeding of "Internatinal Symposium on the Development Water Resource Management System in Mekong Watershed Hanoi, Vietnam, December 2004",   2004年
  • 環境データの解析と環境中生物影響評価―生体汚染の実態解明とその影響評価に関する研究
    環境省環境技術開発等推進事業研究平成14年度報告書「環境中複合化学物質による次世代影響リスクの評価と,   2003年
  • カワウのダイオキシン類汚染と肝チトクロームP-450 系への影響
    平成14年度野生生物のダイオキシン類蓄積状況及び影響調査報告書,   2003年
  • 東京産ハシブトガラスのダイオキシン類汚染と肝チトクローム P-450 系への影響
    平成14年度野生生物のダイオキシン類蓄積状況及び影響調査報告書,   2003年
  • Accumulation of persistent organochlorines in resident white-breasted waterhens (Amaurornis phoenicurus) from Cambodia.
    MONIRITH I, KUNISUE T, IWATA H, TANABE S, TANA T S, Marine Pollution Bulletin, 46, (10) 1341 - 1348,   2003年
  • Contamination by persistent organochlorines in cetaceans incidentally caught along Brazilian coastal waters.
    KAJIWARA N, MATSUOKA S, IWATA H, TANABE S, ROSAS F C W, FILLMANN G, READMAN J W, Archives of Environmental Contamination and Toxicology, 46, (1) 124 - 134,   2004年
  • Contamination of butyltin compounds in Malaysian marine environments.
    SUDARYANTO A, TAKAHASHI S, IWATA H, TANABE S, ISMAIL A, Environmental Pollution, 130, (3) 347 - 358,   2004年
  • Identification of constitutive androstane receptor cDNA in northern fur seal (Callorhinus ursinus).
    Marine Environmental Research, 58, (2-5) 107 - 111,   2004年
  • Identification of aryl hydrocarbon receptor 2 in aquatic birds: cDNA cloning of AHR1 and AHR2 and characteristics of their amino acid sequences.
    Marine Environmental Research, 58, (2-5) 113 - 118,   2004年
  • Searching for novel CYP members using cDNA library from a minke whale liver.
    Marine Environmental Research, 58, (2-5) 495 - 498,   2004年
  • Toxicokinetics of PCDD, PCDF, and coplanar PCB congeners in Baikal seals, Pusa sibirica: age-related accumulation, maternal transfer, and hepatic sequestration.
    IWATA H, WATANABE M, OKAJIMA Y, TANABE S, AMANO M, MIYAZAKI N, PETROV E A, Environmental Science and Technology, 38, (13) 3505 - 3513,   2004年
  • Levels and toxicokinetic behaviors of PCDD, PCDF, and coplanar PCB congeners in common cormorants from Lake Biwa, Japan.
    KUBOTA A, IWATA H, TANABE S, YONEDA K, TOBATA S, Environmental Science and Technology, 38, (14) 3853 - 3859,   2004年
  • Dioxins and related compounds in human breast milk collected around open dumping sites in Asian developing countries: bovine milk as a potential source.
    Archives of Environmental Contamination and Toxicology, 47, (3) 414 - 426,   2004年
  • Mercury contamination in human hair and fish from Cambodia: levels, specific accumulation and risk assessment.
    AGUSA Tetsuro, KUNITO Takashi, IWATA Hisato, MONIRITH In, TANA Touch Seang, SUBRAMANIAN Annamalai, TANABE Shinsuke, Environmental Pollution, 134, (1) 79 - 86,   2004年
  • Contamination by trace elements in groundwater of Vietnam.
    AGUSA T, KUNITO T, FUJIHARA J, KUBOTA R, MINH T B, TRANG P T K, SUBRAMANIAN A, IWATA H, VIET P H, Biomedical Research on Trace Elements, 15, (4) 339 - 341,   2004年
  • バイカルアザラシCYP1A1/1A2の同定およびダイオキシン類蓄積濃度と各mRNA発現量の関係
    平川 周作, 岩田 久人, 金 恩英, 田辺 信介, 宮崎 信之, 環境毒性学会誌, 7, (2) 55 - 59,   2004年
  • Thyroid lesions and dioxin accumulation in the livers of jungle crows (Corvus macrorhynchos) in urban and suburban Tokyo
    KOBAYASHI M., KASHIDA Y., YONEDA K., IWATA H., WATANABE M., TANABE S., FUKATSU H., MACHIDA N., MITSUMORI K., Arch Environ Contam Toxicol, 48, (3) 424 - 432,   2005年
  • Hepatic CYP1A induction by dioxin-like compounds, and congener-specific metabolism and sequestration in wild common cormorants from Lake Biwa, Japan
    KUBOTA Akira, IWATA Hisato, TANABE Shinsuke, YONEDA Kumiko, TOBATA Sachiko, Environ Sci Technol, 39, (10) 3611 - 3619,   2005年
  • Induction of cytochrome P450 1A5 mRNA, protein and enzymatic activities by dioxin-like compounds, and congener-specific metabolism and sequestration in the liver of wild jungle crow (Couvus macrorhynchos) from Tokyo, Japan
    Toxicological Sciences, 88, (2) 384 - 399,   2005年
  • Molecular cloning and mRNA expression of cytochrome P4501A1 and 1A2 in the liver of common minke whales (Balaenoptera acutorostrata)
    NIIMI Satoko, WATANABE Michio X., KIM Eun‐Young, KIM Eun‐Young, IWATA Hisato, YASUNAGA Genta, FUJISE Yoshihiro, TANABE Shinsuke, Marine Pollution Bulletin, 51, (8-12) 784 - 793,   2005年
  • Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels
    Comp Biochem Physiol C Toxicol Pharmacol, 141, (3) 281 - 291,   2005年
  • Molecular characterization of the aryl hydrocarbon receptors (AHR1 and AHR2) from red seabream (Pagrus major)
    Comp Biochem Physiol C Toxicol Pharmacol, 141, (2) 177 - 187,   2005年
  • ダイオキシン暴露によるマダイ胚発生への毒性影響:形態異常の分子メカニズムの解明を目指して
    中毒研究, 18, (4) 333 - 347,   2005年
  • Monitoring of gene expression profiles related to chemical contamination in common cormorant (Phalacrocorax carbo) liver with an oligo array
    Proceedings of COE 1st International Symposium on Environmental Behavior and Ecological Impacts of Persistent Toxic Substances,   2004年
  • Effects of PCDDs/DFs/Co-PCB on hepatic protein expression profile in common cormorant population
    Proceedings of COE 1st International Symposium on Environmental Behavior and Ecological Impacts of Persistent Toxic Substances,   2004年
  • Cytochrome P450 1A4 and 1A5 in common cormorant (Phalacrocorax carbo): evolutionary relationships and functional implications associated with dioxin and related compounds
    Oxford JournalsToxicological Sciences, 92, (2) 394 - 408,   2006年
  • Urinary 8-hydroxy-2'-deoxyguanosine in inhabitants chronically exposed to arsenic in groundwater in Cambodia
    KUBOTA Reiji, KUNITO Takashi, AGUSA Tetsuro, FUJIHARA Junko, MONIRITH In, IWATA Hisato, SUBRAMANIAN Annamalai, TANA Touch Seang, TANABE Shinsuke, Journal of Environmental Monitoring, 8, (2) 293 - 299,   2006年
  • Congener-specific toxicokinetics of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls in black-eared kites (Milvus migrans): cytochrome P4501A-dependent hepatic sequestration
    KUBOTA Akira, IWATA Hisato, TANABE Shinsuke, YONEDA Kumiko, TOBATA Sachiko, Environmental Toxicology and Chemistry, 25, (4) 1007 - 1016,   2006年
  • Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level and ligand profiling in Baikal seal (Pusa sibirica)
    Oxford JournalsToxicological Sciences, 94, (1) 57 - 70,   2006年
  • Toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in developing red seabream (Pagrus major) embryo: an association of morphological deformities with AHR1, AHR2 and CYP1A expressions
    YAMAUCHI Masanobu, YAMAUCHI Masanobu, KIM Eun−young, IWATA Hisato, SHIMA Yasuhiro, TANABE Shinsuke, Elsevier ScienceAquatic Toxicology, 80, (2) 166 - 179,   2006年
  • Contamination by polybrominated diphenyl ethers and persistent organochlorines in catfish and feed from Mekong River Delta, Vietnam.
    HUNG MINH Nguyen, BINH MINH Tu, KAJIWARA Natsuko, KUNISUE Tatsuya, IWATA Hisato, HUNG VIET Pham, CAM TU Nguyen Phuc, CACH TUYEN Bui, TANABE Shinsuke, Environ Toxicol Chem, 25, (10) 2700 - 2708,   2006年
  • Pollution sources and occurrences of selected persistent organic pollutants (POPs) in sediments of the Mekong River delta, South Vietnam
    Chemosphere, 67, (9) 1794 - 1801,   2007年
  • Mercury in hair and blood from residents of Phnom Penh (Cambodia) and possible effect on serum hormone levels
    Chemosphere, xx,   2007年
  • Molecular characterization of two metallothionein isoforms in avian species: Evolutionary history, tissue distribution profile, and expression associated with metal accumulation
    Comp Biochem Physiol C Toxicol Pharmacol, 145, (3) 295 - 305,   2007年
  • Chemical contamination in aquatic ecosystems
    岩田 久人, 金 恩英, 山内 正信, 井上 英, 阿草 哲郎, 田辺 信介, Yakugaku Zasshi, 127, (3) 417 - 428,   2007年
  • Molecular characterization and tissue distribution of aryl hydrocarbon receptor nuclear translocator isoforms, ARNT1 and ARNT2, and identification of novel splice variants in common cormorant (Phalacrocorax carbo)
    Comp Biochem Physiol C Toxicol Pharmacol, 145, (3) 379 - 393,   2007年
  • Persistent Organic Pollutants in Sediments from Sai Gon-Dong Nai River Basin, Vietnam: Levels and Temporal Trends
    Arch Environ Contam Toxicol, xx,   2007年
  • Molecular Characterization of Cytochrome P450 1A1, 1A2 and 1B1, and Effects of Polychlorinated Dibenzo-p-dioxin, Dibenzofuran and Biphenyl Congeners on their Hepatic Expression in Baikal Seal (Pusa sibirica)
    Toxicol Sci, xx,   2007年
  • Toxicogenomic analysis of immune system-related genes in Japanese flounder (Paralichthys olivaceus) exposed to heavy oil
    Marine Pollution Bulletin, 57, (6-12) 445 - 452,   2008年
  • Potential effects of perfluorinated compounds in common cormorants from Lake Biwa, Japan: an implication from the hepatic gene expression profiles by microarray
    NAKAYAMA Kei, IWATA Hisato, TAO Lin, KANNAN Kurunthachalam, IMOTO Mai, KIM Eun‐Young, TASHIRO Kosuke, TANABE Shinsuke, Environmental Toxicology and Chemistry, 27, (11) 2378 - 2386,   2008年
  • カワウ野生個体と培養細胞における遺伝子発現プロファイルの比較
    仲山 慶, 酒井 大樹, 北村 真一, 須藤 明子, 金 恩英, 田辺 信介, 岩田 久人, 環境毒性学会誌, 11, (2) 75 - 81,   2008年
  • Contamination and effects of perfluorochemicals in Baikal seal (Pusa sibirica). 1. Residue level, tissue distribution, and temporal trend.
    ISHIBASHI Hiroshi, IWATA Hisato, KIM Eun−Young, TAO Lin, KANNAN Kurunthachalam, AMANO Masao, MIYAZAKI Nobuyuki, TANABE Shinsuke, BATOEV Valeriy B, PETROV Evgeny A, Environmental Science and Technology, 42, (7) 2295 - 2301,   2008年
  • Contamination and effects of perfluorochemicals in Baikal seal (Pusa sibirica). 2. Molecular characterization, expression level, and transcriptional activation of peroxisome proliferator-activated receptor α.
    ISHIBASHI Hiroshi, IWATA Hisato, KIM Eun−Young, TAO Lin, KANNAN Kurunthachalam, TANABE Shinsuke, BATOEV Valeriy B, PETROV Evgeny A, Environmental Science and Technology, 42, (7) 2302 - 2308,   2008年
  • Specific accumulation of arsenic compounds in green turtles (Chelonia mydas) and hawksbill turtles (Eretmochelys imbricata) from Ishigaki Island.
    AGUSA Tetsuro, TAKAGI Kozue, KUBOTA Reiji, ANAN Yasumi, IWATA Hisato, TANABE Shinsuke, Environmental Pollution, 153, (1) 127 - 136,   2008年
  • Arsenic species and their accumulation features in green turtles (Chelonia mydas).
    Marine Pollution Bulletin, 57, (6-12) 782 - 789,   2008年
  • Interelement relationships and age-related variation of trace element concentrations in liver of striped dolphins (Stenella coeruleoalba) from Japanese coastal waters.
    Marine Pollution Bulletin, 57, (6-12) 807 - 815,   2008年
  • Relationship of urinary arsenic metabolites to intake estimates in residents of the Red River Delta, Vietnam.
    AGUSA Tetsuro, AGUSA Tetsuro, KUNITO Takashi, MINH Tu Binh, MINH Tu Binh, KIM TRANG Pham Thi, IWATA Hisato, VIET Pham Hung, TANABE Shinsuke, Environmental Pollution, 157, (2) 396 - 403,   2009年
  • Dioxin activation of CYP1A5 promoter/enhancer regions from two avian species, common cormorant (Phalacrocorax carbo) and chicken (Gallus gallus) : Association with aryl hydrocarbon receptor 1 and 2 isoforms.
    Toxicology and Applied Pharmacology, 234, (1) 1 - 13,   2009年
  • Functional analysis of avian metallothionein isoforms: An ecotoxicological approach for assessing potential tolerability to element exposure
    NAM Dong‐Ha, KIM Eun‐Young, IWATA Hisato, Environmental Science and Technology, 42, (24) 9391 - 9396,   2008年
  • Alkoxyresorufin (methoxy-, ethoxy-, pentoxy- and benzyloxyresorufin) O-dealkylase activities by in vitro expressed cytochrome P450 1A4 and 1A5 from common cormorant (Phalacrocorax carbo)
    Comparative Biochemistry and Physiology. Toxicology & Pharmacology Part C, 149, (4) 544 - 551,   2009年
  • Accumulation features and temporal trends of PCDDs, PCDFs and PCBs in Baikal seals (Pusa sibirica)
    IMAEDA Daisuke, KUNISUE Tatsuya, KUNISUE Tatsuya, OCHI Yoko, IWATA Hisato, TSYDENOVA Oyuna, TAKAHASHI Shin, AMANO Masao, PETROV Evgeny A., BATOEV Valeriy B., TANABE Shinsuke, Environmental Pollution, 157, (3) 737 - 747,   2009年
  • 8-hydroxy-2’ –deoxyguanosine (8-OHdG) as a possible marker of arsenic posoning: A clinical case study on the relationship between concentrations of 8-OHdG and each arsenic compound in urine of an acute promyelocytic leukemia patient being treated with ・・・
    FUJIHARA Junko, AGUSA Tetsuro, TANAKA Junko, FUJII Yoshimi, MORITANI Tamami, HASEGAWA Masanori, IWATA Hisato, TANABE Shinsuke, TAKESHITA Haruo, Forensic Toxicology, 27, (1) 41 - 44,   2009年, 8-hydroxy-2’ –deoxyguanosine (8-OHdG) as a possible marker of arsenic posoning: A clinical case study on the relationship between concentrations of 8-OHdG and each arsenic compound in urine of an acute promyelocytic leukemia patient being treated with arsenic trioxide
  • Effects of co-exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and perfluorooctane sulfonate or perfluorooctanoic acid on expression of cytochrome P450 isoforms in chicken (Gallus gallus) embryo hepatocyte cultures
    Comparative Biochemistry and Physiology. Toxicology & Pharmacology Part C, 149, (4) 605 - 612,   2009年
  • Transactivation potencies of Baikal seal constitutive active/androstane receptor by persistent organic pollutants and brominated flame retardants.
    SAKAI Hiroki, KIM Eun−Young, PETROV Evgeny A, TANABE Shinsuke, IWATA Hisato, Environmental Science and Technology, 43, (16) 6391 - 6397,   2009年
  • Genetic polymorphisms in AS3MT and arsenic metabolism in residents of the red river delta, vietnam.
    Toxicology and Applied Pharmacology, 236, (2) 131 - 141,   2009年
  • Human exposure to arsenic from groundwater in the red river and mekong river deltas in vietnam.
    International Journal of Environmental Studies, 66, (1) 49 - 57,   2009年
  • Genetic polymorphisms in glutathione S-transferase(GST) superfamily and arsenic metabolism in residents of the Red River Delta, Vietnam.
    AGUSA T., FUJIHARA J., TAKESHITA H., AGUSA T., IWATA H., TANABE S., KUNITO T., MINH T.B., TRANG P.T.K., VIET P.H., Toxicology and Applied Pharmacology, 242, (3) 352 - 362,   2010年
  • Dioxin-like and perfluorinated compounds in pigs in an Indian open waste dumping site: toxicokinetics and effects on hepatic cytochrome P450 and blood plasma hormones.
    WATANABE Michio X., KUNISUE Tatsuya, TAO Lin, KANNAN Kurunthachalam, SUBRAMANIAN Annamalai, TANABE Shinsuke, IWATA Hisato, Environmental Toxicology and Chemistry, 29, (7) 1551 - 1560,   2010年
  • Accumulation features of arsenic in hawksbill turtles and green turtles.
    Biomedical Research on Trace Elements, 19, (1) 63 - 66,   2008年
  • Relationship between genetic polymorphism of arsenic (+3 oxidation state) methyltransferase (AS3MT) and profile of urinary arsenic compounds in Vietnamese.
    Biomedical Research on Trace Elements, 19, (3) 265 - 267,   2008年
  • A microarray data analysis method to evaluate the impact of contaminants on wild animals
    NAKAYAMA Kei, HANDOH Itsuki C., KITAMURA Shin−ichi, KIM Eun−young, IWATA Hisato, TANABE Shinsuke, Science of the Total Environment, 408, (23) 5824 - 5827,   2010年
  • Hepatic CYP1A introduction by chlorinated dioxins and related compounds in the endangered black-footed albatross from the North Pacific.
    KUBOTA Akira, WATANABE Mafumi, KUNISUE Tatsuya, KIM Eun−Young, TANABE Shinsuke, IWATA Hisato, Environmental Science & Technology, 44, (9) 3559 - 3565,   2010年
  • Effects of in ovo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic AHR/ARNT-CYP1A signaling pathways in common cormorants (Phalacrocorax carbo)
    IWATA H., NAGAHAMA N., WATANABE M.X., KIM E.‐Y., SUDO A., Comparative Biochemistry and Physiology, Part C, 152, (2) 224 - 231,   2010年
  • Exposure, metabolism, and health effects of arsenic in residents from arsenic-contaminated groundwater areas of Vietnam and Cambodia: A review
    AGUSA Tetsuro, AGUSA Tetsuro, KUNITO Takashi, KUBOTA Reiji, INOUE Suguru, FUJIHARA Junko, MINH Tu Binh, HA Nguyen Ngoc, CAM TU Nguyen Phuc, TRANG Pham Thi Kim, CHAMNAN Chhoun, TAKESHITA Harao, IWATA Hisato, TUYEN Bui Cach, VIET Pham Hung, TANA Touch Seang, TANABE Shinsuke, Reviews on Environmental Health, 25, (3) 193 - 220,   2010年
  • Evaluation of relative potencies for in vitro transactivation of the baikal seal aryl hydrocarbon receptor by dioxin-like compounds
    KIM Eun‐Young, SUDA Tomoko, TANABE Shinsuke, BATOEV Valeriy B., PETROV Evgeny A., IWATA Hisato, Environmental Science & Tochnology, 45, (4) 1652 - 1658,   2011年
  • Molecular and functional characterization of aryl hydrocarbon receptor nuclear translocator 1 (ARNT1) and ARNT2 in chicken (Gallus gallus)
    LEE Jin‐Seon, IWABUCHI Kohei, IWATA Hisato, KIM Eun‐Young, Comparative Biochemistry and Physiology, Part C, 153, (3) 269 - 279,   2010年
  • Cytochrome P450 CYP2 genes in the commnon cormorant: Evolutionary relationiships with 130 diapsid CYP2 clan sequences and chemical effects on their expression
    KUBOTA Akira, TANABE Shinsuke, IWATA Hisato, KUBOTA Akira, STEGEMAN John J., GOLDSTONE Jared V., NELSON David R., KIM Eun‐Young, Comparative Biochemistry and Physiology, Part C, 153, (3) 280 - 289,   2010年
  • Molecular and functional characterization of aryl hydrocarbon receptor repressor from the chicken (Gallus gallus): interspecies similarities and differences
    LEE Jin−Seon, KIM Eun−Young, NOMARU Koji, IWATA Hisato, Toxicological Sciences, 119, (2) 319 - 334,   2011年
  • Intake and excretion of arsenicals in green (Chelonia mydas) and hawksbill turtles (Eretmochelys imbricata)
    Environmental Chemistry, 8, (1) 19 - 29,   2011年
  • 8-Hydroxy-2'-deoxyguanosine and arsenic compounds in urine and serum of a 4-year-old child suffering from acute promyelocytic leukemia during treatment with arsenic trioxide
    FUJIHARA Junko, HASEGAWA Masanori, KANAI Rie, AGUSA Tetsuro, IWATA Hisato, TANABE Shinsuke, YASUDA Toshihiro, YAMAGUCHI Seiji, TAKESHITA Haruo, Forensic Toxicology, 29, (1) 65 - 68,   2011年
  • ベトナム人におけるAS3MT遺伝子多型とヒ素代謝能の関係
    東洋出版DNA多型, 18,   2010年
  • Molecular and functional characterization of aryl hydrocarbon receptor nuclear translocator 1 (ARNT1) and ARNT2 in chicken (Gallus gallus)
    LEE Jin‐Seon, IWABUCHI Kohei, IWATA Hisato, KIM Eun‐Young, Comparative Biochemistry and Physiology, Part C, 153, (3) 269 - 279,   2011年
  • Cytochrome P450 CYP2 genes in the commnon cormorant: Evolutionary relationiships with 130 diapsid CYP2 clan sequences and chemical effects on their expression
    KUBOTA Akira, TANABE Shinsuke, IWATA Hisato, KUBOTA Akira, STEGEMAN John J., GOLDSTONE Jared V., NELSON David R., KIM Eun‐Young, Comparative Biochemistry and Physiology, Part C, 153, (3) 280 - 289,   2011年

書籍等出版物

作品

  • 野生生物のリスク評価を目指した核内受容体リガンドの網羅的解析法の開発
      2007年 - 2009年

受賞

  •   1994年, 環境汚染と毒性学の分野における優秀論文賞(SCIPRESS) (Quintessence, Excellence in Environmental Contamination and Toxicology (SCIPRESS))
  •   2004年, 1st International Symposium on Environmental Behavior and Ecological Impacts of Persistent Toxic Substances ベストポスター賞
  •   2004年, 7th International Symposium on Cytochrome P-450 Biodiversity and Biotechnology 優秀ポスター賞
  •   2004年, 日本環境毒性学会奨励賞
  •   2005年, 13th Pollutants Response in Marine Organisms (PRIMO13) Best Presentation Award
  •   2005年, 日本環境毒性学会奨励賞
  •   2006年, International Symposium 2006; Pioneering Studies of Young Scientists on Chemical Pollution and Environmental Changes Best Presentation Award
  •   2009年, 15th Pollutants Response in Marine Organisms (PRIMO15) Best Presentation Award
  •   2011年, 第16回琵琶湖生態学賞

競争的資金



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