Graduate School of Science and Engineering（Science）
理工学専攻（生物環境科学）
日本語
Update date：2025/01/08
Professor
Sato Yasushi

Affiliation

  1. Ehime University大学院理工学研究科 環境機能科学専攻教授

Research History

  1. 1995/06-1996/03Ehime UniversityFaculty of Science, Department of Biology助手
  2. 1996/04-2005/03Ehime UniversityFaculty of Science助手
  3. 2005/04-2006/03Ehime UniversityFaculty of Science, Department of Biology特任講師
  4. 2006/04-2007/03Ehime UniversityGraduate School of Science and Engineering, Chemistry and Biology助手
  5. 2007/04-2020/09Ehime UniversityGraduate School of Science and Engineering, Chemistry and Biology准教授
  6. 2020/10-presentEhime UniversityGraduate School of Science and Engineering, Chemistry and Biology教授

Education

  1. Tohoku University1985/041989/03
  2. 東北大学大学院1989/041991/03
  3. 東北大学大学院1991/041994/03
  4. 東北大学大学院1994/041995/05

Degree

  1. Doctor(science)Tohoku University

Research Areas

Research Interests

  1. UDP-N-acetylglucosamine (UDP-GlcNAc)
  2. lignin synthesis
  3. peroxidase
  4. laccase
  5. tracheary element differentiation
  6. cell wall
  7. morphogenesis
  8. environmental response
  9. リグニン合成
  10. ペルオキシダーゼ
  11. ラッカーゼ
  12. 管状要素分化
  13. 細胞壁
  14. 形態形成
  15. 環境応答

Research Projects

  1. Physiological significance of UDP-N-acetylglucosamine biosynthesis in plants基盤研究(C)2013/04-2016/03Principal investigator
  2. 日本学術振興会：科研費奨励研究(A)ヒャクニチソウ管状要素分化実験系を用いたリグニン合成ペルオキシダーゼ遺伝子の解析1997/04-1999/03Principal investigator
View details...

Books and Other Publications

  1. 木質の形成 第3版 (バイオマス科学への招待)福島 和彦 船田 良 杉山 淳司 高部 圭司 梅澤 俊明 山本 浩之 青木 弾4.3 リグニン形成の分子機構海青社2024/03/314860993748
  2. 木質の形成 第2版: バイオマス科学への招待福島 和彦 船田 良 杉山 淳司 高部 圭司 梅澤 俊明 山本 浩之細胞の分化とリグニン形成の分子機構海青社2011/104860992520
  3. Immunoelectron Microscopy. Methods and Protocols.SATO Seiichi SATO YasushiLocalization of rDNA at nucleolar structural components by immunoelectron microscopy.Springer20109781607617839
  4. 木質の形成－バイオマス科学への招待福島 和彦 船田 良 杉山 淳司 高部 圭司 梅澤 俊明 山本 浩之細胞の分化とリグニン形成の分子機構海青社2003/034860992024
  5. Molecular Breeding of Woody PlantsSATO YasushiSpatial and temporal regulation of lignifcation during tracheary element differentiation.Elsevier20019780080536750
View details...

Papers

  1. THESEUS1 is involved in tunicamycin-induced root growth inhibition, ectopic lignin deposition, and cell wall damage-induced unfolded protein response2022/06/25Masato Nakamura Mamoru Nozaki Yuji Iwata Nozomu Koizumi Yasushi SatoPlant Biotechnology39/ 2, 129-138Research paper (scientific journal)10.5511/plantbiotechnology.21.1224aURLJapanese Society for Plant Cell and Molecular Biology
  2. Interference of Arabidopsis N-Acetylglucosamine-1-P Uridylyltransferase Expression Impairs Protein N-Glycosylation and Induces ABA-Mediated Salt Sensitivity During Seed Germination and Early Seedling Development2022/06/07Ya-Huei Chen Hwei-Ling Shen Shu-Jen Chou Yasushi Sato Wan-Hsing ChengFrontiers in Plant Science13Research paper (scientific journal)10.3389/fpls.2022.903272URLFrontiers Media SAN-acetylglucosamine (GlcNAc) is the fundamental amino sugar moiety that is essential for protein glycosylation. UDP-GlcNAc, an active form of GlcNAc, is synthesized through the hexosamine biosynthetic pathway (HBP). Arabidopsis N-acetylglucosamine-1-P uridylyltransferases (GlcNAc1pUTs), encoded by GlcNA.UTs, catalyze the last step in the HBP pathway, but their biochemical and molecular functions are less clear. In this study, the GlcNA.UT1 expression was knocked down by the double-stranded RNA interference (dsRNAi) in the glcna.ut2 null mutant background. The RNAi transgenic plants, which are referred to as iU1, displayed the reduced UDP-GlcNAc biosynthesis, altered protein N-glycosylation and induced an unfolded protein response under salt-stressed conditions. Moreover, the iU1 transgenic plants displayed sterility and salt hypersensitivity, including delay of both seed germination and early seedling establishment, which is associated with the induction of ABA biosynthesis and signaling. These salt hypersensitive phenotypes can be rescued by exogenous fluridone, an inhibitor of ABA biosynthesis, and by introducing an ABA-deficient mutant allele nced3 into iU1 transgenic plants. Transcriptomic analyses further supported the upregulated genes that were involved in ABA biosynthesis and signaling networks, and response to salt stress in iU1 plants. Collectively, these data indicated that GlcNAc1pUTs are essential for UDP-GlcNAc biosynthesis, protein N-glycosylation, fertility, and the response of plants to salt stress through ABA signaling pathways during seed germination and early seedling development.
  3. Temperature-dependent fasciation mutants provide a link between mitochondrial RNA processing and lateral root morphogenesis2021/01/14Kurataka Otsuka Akihito Mamiya Mineko Konishi Mamoru Nozaki Atsuko Kinoshita Hiroaki Tamaki Masaki Arita Masato Saito Kayoko Yamamoto Takushi Hachiya Ko Noguchi Takashi Ueda Yusuke Yagi Takehito Kobayashi Takahiro Nakamura Yasushi Sato Takashi Hirayama Munetaka SugiyamaeLife10/ e61611, 1-26Research paper (scientific journal)10.7554/elife.61611URLURL_2eLife Sciences Publications, LtdAlthough mechanisms that activate organogenesis in plants are well established, much less is known about the subsequent fine-tuning of cell proliferation, which is crucial for creating properly structured and sized organs. Here we show, through analysis of temperature-dependent fasciation (TDF) mutants of Arabidopsis, <italic>root redifferentiation defective 1</italic> (<italic>rrd1</italic>), <italic>rrd2</italic>, and <italic>root initiation defective 4</italic> (<italic>rid4</italic>), that mitochondrial RNA processing is required for limiting cell division during early lateral root (LR) organogenesis. These mutants formed abnormally broadened (i.e. fasciated) LRs under high-temperature conditions due to extra cell division. All TDF proteins localized to mitochondria, where they were found to participate in RNA processing: RRD1 in mRNA deadenylation, and RRD2 and RID4 in mRNA editing. Further analysis suggested that LR fasciation in the TDF mutants is triggered by reactive oxygen species generation caused by defective mitochondrial respiration. Our findings provide novel clues for the physiological significance of mitochondrial activities in plant organogenesis.
  4. Image analysis of stress-induced lignin deposition in Arabidopsis thaliana using the macro program LigninJ for ImageJ software2020/03/25Masato Nakamura Tomoaki Kamehama Yasushi SatoPlant Biotechnology37/ 1, 105-109Research paper (scientific journal)10.5511/plantbiotechnology.20.0110aURLJapanese Society for Plant Cell and Molecular Biology
  5. Establishment of an aseptic culture system and analysis of the effective growth conditions for Eleocharis acicularis ramets for use in phytoremediation2017/06Sato Y Goto S Teraoka S Takagaki K Takehara A Sano S Sakakibara MEnvironments4/ 2, 40Research paper (scientific journal)10.3390/environments4020040
View details...

Presentations

  1. ヘキソサミン経路の植物特異的機能解明に向けたシロイヌ ナズナ・ホスホアセチルグルコサミンムターゼの解析日本植物学会 第88回大会2024/09/16Poster presentation
  2. ヘキソサミン異化経路導入シロイヌナズナにおけるグルコサミン類及びキチン・キトサン利用能力の変化日本植物学会 第88回大会2024/09/16Poster presentation
  3. シロイヌナズナにおけるヘキソサミン経路の適度な活性化による，非生物ストレス 耐性向上と内生物質量の変化日本植物学会 第88回大会2024/09/14Oral presentation(general)
  4. ヘキソサミン異化経路導入シロイヌナズナにおけるグルコサミン類及びそのポリマーの影響中国四国植物学会 第80回大会2024/05/11Poster presentation
  5. フィードバック制御抑制GFAT導入シロイヌナズナが示す非生物的ストレス耐性の向上日本植物学会第87回大会2023/09/04Poster presentation
View details...

Allotted Class

  1. 2024Basic Experiments in Biology
  2. 2024Experiment in BiologyⅢ
  3. 2024Basic Experiments in Biology
  4. 2024Perspectives for Modern BiologyⅠ
  5. 2024Special Lecture on BiologyⅠ
View details...

Social Activities

  1. 親子で楽しむ科学実験2019/08/24-2019/08/25
  2. 親子で楽しむ科学実験2016/08/20-2016/08/21
  3. 親子で楽しむ科学実験2015/08/22-2015/08/23
View details...

Academic_Activities

  1. The 29th Biennial Conference of the Asian Association for Biology Education (AABE2024), Conference AdministrationPlanning,management,etc.,Panel moderator,session chair,etc.The Asian Association for Biology Education (AABE)2024/10/12-2024/10/14
View details...

Professional Memberships

  1. 日本植物バイオテクノロジー学会
  2. 中国四国植物学会
  3. The Japanese Society of Plant Physiologists
  4. The Botanical Society of Japan
  5. American Society of Plant Biologists
View details...